Tcirg1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3) - Rat Genome Database

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Gene: Tcirg1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3) Heterocephalus glaber
Analyze
Symbol: Tcirg1
Name: T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
RGD ID: 18929796
Description: ENCODES a protein that exhibits ATPase binding (inferred); proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN apoptotic process (ortholog); autophagosome assembly (ortholog); autophagy (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); autosomal recessive osteopetrosis 1 (ortholog); choreaacanthocytosis (ortholog); FOUND IN apical plasma membrane (ortholog); late endosome (ortholog); lysosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: V-type proton ATPase 116 kDa subunit a
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476718,809,689 - 18,820,390 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476718,809,626 - 18,820,360 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tcirg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476718,809,689 - 18,820,390 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476718,809,626 - 18,820,360 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TCIRG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381168,039,025 - 68,053,762 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1168,039,025 - 68,050,895 (+)EnsemblGRCh38hg38GRCh38
GRCh371167,806,492 - 67,818,362 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,563,059 - 67,574,942 (+)NCBINCBI36Build 36hg18NCBI36
Celera1165,140,155 - 65,152,040 (+)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1164,141,805 - 64,153,709 (+)NCBIHuRef
CHM1_11167,690,218 - 67,702,120 (+)NCBICHM1_1
T2T-CHM13v2.01168,042,666 - 68,057,403 (+)NCBIT2T-CHM13v2.0
Tcirg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,946,050 - 3,957,717 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,946,050 - 3,957,133 (-)EnsemblGRCm39 Ensembl
GRCm38193,896,050 - 3,907,133 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,896,050 - 3,907,133 (-)EnsemblGRCm38mm10GRCm38
MGSCv37193,896,050 - 3,907,133 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36193,896,053 - 3,905,230 (-)NCBIMGSCv36mm8
Celera193,776,425 - 3,787,508 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.62NCBI
Tcirg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,556,270 - 210,568,021 (-)NCBIGRCr8
mRatBN7.21201,127,034 - 201,138,787 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1201,127,034 - 201,138,742 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1209,500,301 - 209,509,672 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01216,589,084 - 216,598,473 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01209,263,286 - 209,272,675 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,126,687 - 219,139,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,127,602 - 219,139,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01225,999,292 - 226,012,069 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,420,106 - 206,429,495 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11206,573,497 - 206,585,222 (-)NCBI
Celera1198,679,648 - 198,689,037 (-)NCBICelera
Cytogenetic Map1q43NCBI
Tcirg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542217,768,469 - 17,779,003 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542217,768,469 - 17,778,976 (-)NCBIChiLan1.0ChiLan1.0
TCIRG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2968,989,593 - 69,001,506 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11170,032,855 - 70,044,768 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01163,120,913 - 63,132,831 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11166,429,435 - 66,441,327 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,429,435 - 66,441,327 (+)Ensemblpanpan1.1panPan2
TCIRG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11849,784,480 - 49,794,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1849,784,490 - 49,794,317 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1848,393,818 - 48,403,688 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,705,711 - 50,715,580 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1850,703,574 - 50,715,558 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11849,919,281 - 49,929,147 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01849,494,101 - 49,503,970 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01850,287,643 - 50,297,518 (-)NCBIUU_Cfam_GSD_1.0
Tcirg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049475,627,790 - 5,636,842 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365992,066,847 - 2,079,206 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365992,070,211 - 2,079,169 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCIRG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl24,844,637 - 4,860,498 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.124,844,627 - 4,860,562 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,476,372 - 3,488,494 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TCIRG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116,484,469 - 6,497,008 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl16,484,474 - 6,494,719 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038103,762,696 - 103,775,284 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026074   ⟹   ENSHGLP00000025845
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476718,809,689 - 18,820,390 (-)Ensembl
RefSeq Acc Id: XM_004852199   ⟹   XP_004852256
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476718,809,626 - 18,820,325 (-)NCBI
RefSeq Acc Id: XM_013074711   ⟹   XP_012930165
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476718,809,626 - 18,819,649 (-)NCBI
RefSeq Acc Id: XM_021264485   ⟹   XP_021120144
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476718,809,626 - 18,818,670 (-)NCBI
RefSeq Acc Id: XM_021264486   ⟹   XP_021120145
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476718,809,626 - 18,818,670 (-)NCBI
RefSeq Acc Id: XM_021264487   ⟹   XP_021120146
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476718,809,626 - 18,820,360 (-)NCBI
RefSeq Acc Id: XP_021120146   ⟸   XM_021264487
- Peptide Label: isoform X3
- UniProtKB: G5BTV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004852256   ⟸   XM_004852199
- Peptide Label: isoform X3
- UniProtKB: G5BTV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012930165   ⟸   XM_013074711
- Peptide Label: isoform X3
- UniProtKB: G5BTV6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120145   ⟸   XM_021264486
- Peptide Label: isoform X2
- UniProtKB: A0AAX6TJX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120144   ⟸   XM_021264485
- Peptide Label: isoform X1
- UniProtKB: A0AAX6TF38 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025845   ⟸   ENSHGLT00000026074


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018395 Ensembl, ENTREZGENE
  ENSHGLG00100014181 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000026074 ENTREZGENE
  ENSHGLT00100019437 UniProtKB/TrEMBL
InterPro V-ATPase_116kDa_su UniProtKB/TrEMBL
  V-type_ATPase_116kDa_su_euka UniProtKB/TrEMBL
KEGG Report hgl:101720677 UniProtKB/TrEMBL
NCBI Gene Tcirg1 ENTREZGENE
PANTHER PTHR11629 UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE 116 KDA SUBUNIT A3 UniProtKB/TrEMBL
Pfam V_ATPase_I UniProtKB/TrEMBL
PIRSF ATP6V0A1 UniProtKB/TrEMBL
UniProt A0AAX6TF38 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TJX8 ENTREZGENE, UniProtKB/TrEMBL
  G5BTV6 ENTREZGENE, UniProtKB/TrEMBL