Nucb1 (nucleobindin 1) - Rat Genome Database

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Gene: Nucb1 (nucleobindin 1) Heterocephalus glaber
Analyze
Symbol: Nucb1
Name: nucleobindin 1
RGD ID: 18929281
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); G-protein alpha-subunit binding (ortholog); INVOLVED IN regulation of protein targeting (ortholog); small GTPase-mediated signal transduction (ortholog); ASSOCIATED WITH Stevens-Johnson syndrome (ortholog); FOUND IN early endosome (ortholog); extracellular region (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nucleobindin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,071,869 - 5,085,623 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248325,073,022 - 5,085,493 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nucb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,071,869 - 5,085,623 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248325,073,022 - 5,085,493 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
NUCB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,900,312 - 48,923,372 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,900,050 - 48,923,473 (+)Ensemblhg38GRCh38
GRCh371949,403,569 - 49,426,629 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,091,637 - 54,118,340 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341954,095,852 - 54,118,337NCBI
Celera1946,270,663 - 46,293,902 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,779,769 - 45,802,972 (+)NCBIHuRef
CHM1_11949,405,174 - 49,428,729 (+)NCBICHM1_1
T2T-CHM13v2.01951,895,140 - 51,918,232 (+)NCBIT2T-CHM13v2.0
Nucb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,142,300 - 45,159,813 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,139,882 - 45,159,830 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38745,492,674 - 45,510,408 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,490,458 - 45,510,406 (-)Ensemblmm10GRCm38
MGSCv37752,748,044 - 52,765,778 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36745,361,150 - 45,378,372 (-)NCBIMGSCv36mm8
Celera740,949,201 - 40,966,928 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.33NCBI
Nucb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,104,793 - 105,135,730 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1105,104,793 - 105,135,837 (-)EnsemblGRCr8
mRatBN7.2195,968,325 - 95,999,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,968,326 - 96,003,220 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1101,353,752 - 101,373,866 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,826,428 - 109,846,542 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,116,822 - 103,136,934 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,480,160 - 101,511,029 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,480,145 - 101,500,850 (-)Ensemblrn6Rnor6.0
Rnor_5.01102,559,072 - 102,579,628 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4195,961,163 - 95,981,910 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera190,224,246 - 90,244,279 (-)NCBICelera
RGSC_v3.1196,039,273 - 96,060,021 (-)NCBI
Cytogenetic Map1q22NCBI
Nucb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,722,411 - 1,740,596 (-)Ensembl
ChiLan1.0NW_0049555591,723,986 - 1,739,776 (-)NCBIChiLan1.0ChiLan1.0
NUCB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,003,893 - 55,026,955 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,930,112 - 56,953,069 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,900,098 - 45,923,056 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,831,582 - 54,856,711 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,832,426 - 54,855,962 (-)EnsemblpanPan2panpan1.1
NUCB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,453,965 - 107,476,458 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,454,636 - 107,476,375 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1106,976,497 - 106,999,075 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01107,978,613 - 108,001,223 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,978,615 - 108,001,085 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,646,057 - 107,668,201 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,292,476 - 107,315,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,128,088 - 108,150,670 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nucb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,305,942 - 21,327,980 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,924,719 - 2,945,178 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,924,186 - 2,946,035 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUCB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,180,038 - 54,209,930 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1654,186,610 - 54,209,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,119,224 - 50,141,964 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUCB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,133,505 - 42,154,461 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607322,017,037 - 22,040,686 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000020807   ⟹   ENSHGLP00000020605
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248325,071,869 - 5,085,623 (-)Ensembl
RefSeq Acc Id: XM_004866975   ⟹   XP_004867032
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248325,073,022 - 5,085,493 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004867032 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020605
GenBank Protein JAN99453 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004867032   ⟸   XM_004866975
- UniProtKB: A0A0N8ETJ8 (UniProtKB/TrEMBL),   G5BAG8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000020605   ⟸   ENSHGLT00000020807


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014738 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020807 ENTREZGENE
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Nucleobindin UniProtKB/TrEMBL
KEGG Report hgl:101714966 UniProtKB/TrEMBL
NCBI Gene Nucb1 ENTREZGENE
PANTHER PTHR19237 UniProtKB/TrEMBL
  PTHR19237:SF21 UniProtKB/TrEMBL
Pfam NUCB1_N UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A0N8ETJ8 ENTREZGENE, UniProtKB/TrEMBL
  G5BAG8 ENTREZGENE, UniProtKB/TrEMBL