Ncoa1 (nuclear receptor coactivator 1) - Rat Genome Database

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Gene: Ncoa1 (nuclear receptor coactivator 1) Heterocephalus glaber
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Symbol: Ncoa1
Name: nuclear receptor coactivator 1
RGD ID: 18928592
Description: ENCODES a protein that exhibits nuclear estrogen receptor binding (ortholog); nuclear receptor binding (ortholog); nuclear retinoic acid receptor binding (ortholog); INVOLVED IN cellular response to hormone stimulus (ortholog); cerebellum development (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; cortisol signaling pathway; ASSOCIATED WITH breast carcinoma (ortholog); Breast Neoplasms (ortholog); endometrial carcinoma (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247386,943,726 - 7,054,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247386,770,745 - 7,054,616 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ncoa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247386,943,726 - 7,054,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247386,770,745 - 7,054,616 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NCOA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38224,491,254 - 24,770,702 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl224,491,254 - 24,770,702 (+)EnsemblGRCh38hg38GRCh38
GRCh37224,714,123 - 24,993,571 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36224,660,850 - 24,847,075 (+)NCBINCBI36Build 36hg18NCBI36
Build 34224,718,996 - 24,905,219NCBI
Celera224,648,250 - 24,833,882 (+)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef224,545,896 - 24,731,418 (+)NCBIHuRef
CHM1_1224,736,919 - 24,923,129 (+)NCBICHM1_1
T2T-CHM13v2.0224,525,913 - 24,805,480 (+)NCBIT2T-CHM13v2.0
Ncoa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,297,362 - 4,569,452 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl124,297,362 - 4,527,182 (-)EnsemblGRCm39 Ensembl
GRCm38124,247,362 - 4,477,206 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl124,247,362 - 4,477,182 (-)EnsemblGRCm38mm10GRCm38
MGSCv37124,247,362 - 4,484,060 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36124,257,424 - 4,491,127 (-)NCBIMGSCv36mm8
Celera124,179,857 - 4,348,692 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map122.05NCBI
Ncoa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8632,952,090 - 33,229,829 (-)NCBIGRCr8
mRatBN7.2627,232,609 - 27,507,992 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl627,232,611 - 27,475,664 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx627,524,867 - 27,768,734 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0627,840,748 - 28,084,625 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0627,318,440 - 27,562,032 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0628,677,563 - 28,931,844 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl628,677,540 - 28,931,843 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0638,483,476 - 38,734,322 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4627,224,396 - 27,473,926 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1627,229,075 - 27,336,790 (-)NCBI
Celera626,704,021 - 26,946,167 (-)NCBICelera
Cytogenetic Map6q14NCBI
Ncoa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554696,794,821 - 6,892,566 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554696,676,780 - 6,892,587 (+)NCBIChiLan1.0ChiLan1.0
NCOA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212101,755,028 - 102,031,268 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A101,759,056 - 102,035,245 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A24,485,068 - 24,764,135 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A24,581,645 - 24,859,488 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A24,733,117 - 24,859,488 (+)Ensemblpanpan1.1panPan2
NCOA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11718,880,676 - 19,124,300 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1718,880,383 - 19,122,258 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1718,777,980 - 19,021,230 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01719,302,445 - 19,397,682 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1719,153,592 - 19,396,341 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11718,890,805 - 19,134,195 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01718,899,937 - 19,143,634 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01718,940,197 - 19,183,703 (+)NCBIUU_Cfam_GSD_1.0
Ncoa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629263,234,427 - 63,471,108 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364937,368,462 - 7,465,615 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364937,368,393 - 7,605,754 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCOA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3113,999,253 - 114,250,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13113,997,214 - 114,251,080 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23121,230,135 - 121,286,004 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.23121,349,942 - 121,379,022 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NCOA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11482,898,368 - 83,028,137 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1482,897,348 - 83,013,589 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604528,994,261 - 29,270,072 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004839447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01015567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01015584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH173149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000023312   ⟹   ENSHGLP00000023097
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247386,943,726 - 7,052,481 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000023313   ⟹   ENSHGLP00000023098
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,007,131 - 7,054,454 (+)Ensembl
RefSeq Acc Id: XM_004839447   ⟹   XP_004839504
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247386,770,745 - 7,054,616 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004839504 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16001 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023097
RefSeq Acc Id: XP_004839504   ⟸   XM_004839447
- UniProtKB: A0AAX6NY40 (UniProtKB/TrEMBL),   G5C390 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000023098   ⟸   ENSHGLT00000023313
Ensembl Acc Id: ENSHGLP00000023097   ⟸   ENSHGLT00000023312


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016470 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023312 ENTREZGENE
Gene3D-CATH 6.10.140.410 UniProtKB/TrEMBL
  Helix-loop-helix DNA-binding domain UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  NCO_DUF1518 UniProtKB/TrEMBL
  NCOA1_bHLH UniProtKB/TrEMBL
  Nuc_rcpt_coact UniProtKB/TrEMBL
  Nuc_rcpt_coact_Ncoa-typ UniProtKB/TrEMBL
  Nuc_rcpt_coact_Ncoa_int_sf UniProtKB/TrEMBL
  Nuclear_rcpt_coactivator UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
  SRC/p160_LXXLL UniProtKB/TrEMBL
NCBI Gene Ncoa1 ENTREZGENE
PANTHER NUCLEAR RECEPTOR COACTIVATOR UniProtKB/TrEMBL
  NUCLEAR RECEPTOR COACTIVATOR 1 UniProtKB/TrEMBL
Pfam DUF1518 UniProtKB/TrEMBL
  NCOA_u2 UniProtKB/TrEMBL
  Nuc_rec_co-act UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS_11 UniProtKB/TrEMBL
  SRC-1 UniProtKB/TrEMBL
PIRSF Nuclear_receptor_coactivator UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART DUF1518 UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP HLH, helix-loop-helix DNA-binding domain UniProtKB/TrEMBL
  Nuclear receptor coactivator interlocking domain UniProtKB/TrEMBL
  PYP-like sensor domain (PAS domain) UniProtKB/TrEMBL
UniProt A0AAX6NY40 ENTREZGENE, UniProtKB/TrEMBL
  G5C390 ENTREZGENE, UniProtKB/TrEMBL