Slc1a4 (solute carrier family 1 member 4) - Rat Genome Database

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Gene: Slc1a4 (solute carrier family 1 member 4) Heterocephalus glaber
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Symbol: Slc1a4
Name: solute carrier family 1 member 4
RGD ID: 18927644
Description: ENCODES a protein that exhibits chloride channel activity (ortholog); L-cystine transmembrane transporter activity (ortholog); L-hydroxyproline transmembrane transporter activity (ortholog); INVOLVED IN cognition (ortholog); hydroxyproline transport (ortholog); L-alanine import across plasma membrane (ortholog); PARTICIPATES IN argininosuccinic aciduria pathway; carbamoyl phosphate synthetase I deficiency pathway; citrullinemia pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); microcephaly (ortholog); FOUND IN centrosome (ortholog); dendrite (ortholog); intermediate filament (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Neutral amino acid transporter A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247628,532,063 - 8,558,994 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247628,532,550 - 8,558,912 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc1a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247628,532,063 - 8,558,994 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247628,532,550 - 8,558,912 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SLC1A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38264,988,479 - 65,023,865 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl264,988,477 - 65,023,865 (+)EnsemblGRCh38hg38GRCh38
GRCh37265,215,613 - 65,250,999 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36265,070,098 - 65,104,503 (+)NCBINCBI36Build 36hg18NCBI36
Build 34265,128,244 - 65,162,648NCBI
Celera265,061,957 - 65,097,385 (+)NCBICelera
Cytogenetic Map2p14NCBI
HuRef264,949,345 - 64,984,802 (+)NCBIHuRef
CHM1_1265,146,566 - 65,181,989 (+)NCBICHM1_1
T2T-CHM13v2.0264,998,100 - 65,033,490 (+)NCBIT2T-CHM13v2.0
Slc1a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,252,180 - 20,282,713 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,252,180 - 20,282,713 (-)EnsemblGRCm39 Ensembl
GRCm381120,302,180 - 20,332,713 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,302,180 - 20,332,713 (-)EnsemblGRCm38mm10GRCm38
MGSCv371120,202,183 - 20,232,716 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361120,202,208 - 20,232,674 (-)NCBIMGSCv36mm8
Celera1122,451,521 - 22,482,559 (-)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1112.97NCBI
Slc1a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,718,646 - 98,761,672 (-)NCBIGRCr8
mRatBN7.21494,530,801 - 94,560,190 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,529,084 - 94,560,418 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1498,877,394 - 98,907,056 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014100,117,664 - 100,147,323 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,585,031 - 96,614,695 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,582,884 - 104,612,417 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,581,190 - 104,612,597 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014104,317,800 - 104,345,829 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414101,123,740 - 101,153,790 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114101,142,950 - 101,173,001 (-)NCBI
Celera1493,550,109 - 93,578,743 (-)NCBICelera
Cytogenetic Map14q22NCBI
Slc1a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542419,474,082 - 19,499,592 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542419,474,082 - 19,499,592 (-)NCBIChiLan1.0ChiLan1.0
SLC1A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21261,377,645 - 61,412,341 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A61,380,650 - 61,416,291 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A65,051,025 - 65,086,917 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A66,177,835 - 66,212,249 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A66,176,925 - 66,209,615 (+)Ensemblpanpan1.1panPan2
SLC1A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11064,482,840 - 64,508,288 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1064,483,060 - 64,505,747 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1064,369,739 - 64,394,932 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01065,493,157 - 65,518,318 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1065,492,613 - 65,518,315 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11065,172,083 - 65,197,216 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01065,480,918 - 65,503,851 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01065,774,013 - 65,799,174 (+)NCBIUU_Cfam_GSD_1.0
Slc1a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629218,780,757 - 18,810,279 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364919,760,952 - 9,790,536 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364919,761,002 - 9,790,535 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC1A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl376,938,107 - 76,970,508 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1376,938,102 - 76,970,519 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2380,747,982 - 80,754,397 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC1A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11441,999,216 - 42,032,326 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1441,999,064 - 42,032,288 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604569,848,255 - 69,881,833 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000005548   ⟹   ENSHGLP00000005477
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247628,532,063 - 8,558,994 (-)Ensembl
RefSeq Acc Id: XM_004849965   ⟹   XP_004850022
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247628,532,550 - 8,558,912 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004850022 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16952 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005477
RefSeq Acc Id: XP_004850022   ⟸   XM_004849965
- UniProtKB: G5C5Z1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000005477   ⟸   ENSHGLT00000005548


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004016 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005548 ENTREZGENE
Gene3D-CATH 1.10.3860.10 UniProtKB/TrEMBL
InterPro DAACS UniProtKB/TrEMBL
  Na-dicarboxylate_symporter UniProtKB/TrEMBL
  Na-dicarboxylate_symporter_CS UniProtKB/TrEMBL
  Na:dicarbo_symporter_sf UniProtKB/TrEMBL
KEGG Report hgl:101713943 UniProtKB/TrEMBL
NCBI Gene Slc1a4 ENTREZGENE
PANTHER NEUTRAL AMINO ACID TRANSPORTER A UniProtKB/TrEMBL
  SODIUM/DICARBOXYLATE SYMPORTER-RELATED UniProtKB/TrEMBL
Pfam SDF UniProtKB/TrEMBL
PRINTS EDTRNSPORT UniProtKB/TrEMBL
PROSITE NA_DICARBOXYL_SYMP_1 UniProtKB/TrEMBL
  NA_DICARBOXYL_SYMP_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF118215 UniProtKB/TrEMBL
UniProt G5C5Z1 ENTREZGENE, UniProtKB/TrEMBL