Apbb1 (amyloid beta precursor protein binding family B member 1) - Rat Genome Database

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Gene: Apbb1 (amyloid beta precursor protein binding family B member 1) Heterocephalus glaber
Analyze
Symbol: Apbb1
Name: amyloid beta precursor protein binding family B member 1
RGD ID: 18927437
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); chromatin binding (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN axon guidance (ortholog); central nervous system neuron differentiation (ortholog); DNA damage response (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injuries (ortholog); genetic disease (ortholog); FOUND IN dendritic spine (ortholog); endoplasmic reticulum (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: amyloid beta A4 precursor protein-binding family B member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248177,909,468 - 7,936,487 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248177,913,541 - 7,937,945 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Apbb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248177,909,468 - 7,936,487 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248177,913,541 - 7,937,945 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
APBB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,395,124 - 6,419,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,395,125 - 6,419,414 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,416,354 - 6,440,683 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,372,931 - 6,397,220 (-)NCBINCBI36Build 36hg18NCBI36
Build 34116,372,930 - 6,397,220NCBI
Celera116,535,423 - 6,559,715 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef116,075,464 - 6,099,756 (-)NCBIHuRef
CHM1_1116,415,490 - 6,439,780 (-)NCBICHM1_1
T2T-CHM13v2.0116,453,583 - 6,477,913 (-)NCBIT2T-CHM13v2.0
Apbb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,207,691 - 105,231,151 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7105,207,690 - 105,230,860 (-)EnsemblGRCm39 Ensembl
GRCm387105,558,465 - 105,581,924 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,558,483 - 105,581,653 (-)EnsemblGRCm38mm10GRCm38
MGSCv377112,706,998 - 112,730,049 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367105,432,305 - 105,455,356 (-)NCBIMGSCv36mm8
Celera7105,829,626 - 105,852,681 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.9NCBI
Apbb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81169,308,719 - 169,332,372 (-)NCBIGRCr8
mRatBN7.21159,896,889 - 159,920,505 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1159,896,880 - 159,920,627 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1167,919,373 - 167,935,733 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01175,105,367 - 175,121,733 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01168,007,191 - 168,023,554 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01170,387,625 - 170,411,263 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1170,387,609 - 170,404,056 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01177,393,531 - 177,417,140 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,282,918 - 163,299,333 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11163,378,394 - 163,394,810 (-)NCBI
Celera1157,829,568 - 157,845,995 (-)NCBICelera
Cytogenetic Map1q32NCBI
Apbb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541422,117,470 - 22,137,849 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541422,121,867 - 22,137,849 (-)NCBIChiLan1.0ChiLan1.0
APBB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v298,831,613 - 8,855,768 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1118,795,471 - 8,819,634 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,526,477 - 6,550,509 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,210,077 - 6,233,992 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,209,812 - 6,225,972 (-)Ensemblpanpan1.1panPan2
APBB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12129,719,386 - 29,741,658 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2129,719,589 - 29,759,046 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2129,421,423 - 29,443,492 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02130,545,680 - 30,567,749 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2130,545,331 - 30,585,167 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12129,866,583 - 29,888,629 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02130,032,363 - 30,054,462 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02130,227,710 - 30,249,777 (-)NCBIUU_Cfam_GSD_1.0
Apbb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494756,198,968 - 56,222,805 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936842452,681 - 476,513 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936842452,682 - 476,533 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APBB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl93,303,112 - 3,324,037 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.193,303,032 - 3,323,828 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.293,964,689 - 3,977,972 (-)NCBISscrofa10.2Sscrofa10.2susScr3
APBB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1158,407,323 - 58,431,551 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl158,421,847 - 58,431,144 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038156,233,110 - 156,257,185 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000014733   ⟹   ENSHGLP00000014588
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248177,909,468 - 7,936,487 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000014734   ⟹   ENSHGLP00000014589
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248177,909,468 - 7,923,790 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000014735   ⟹   ENSHGLP00000014590
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248177,913,544 - 7,928,770 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000014736   ⟹   ENSHGLP00000014591
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248177,920,629 - 7,923,275 (-)Ensembl
RefSeq Acc Id: XM_004863384   ⟹   XP_004863441
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,936,504 (-)NCBI
RefSeq Acc Id: XM_004863385   ⟹   XP_004863442
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,936,504 (-)NCBI
RefSeq Acc Id: XM_004863386   ⟹   XP_004863443
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,936,504 (-)NCBI
RefSeq Acc Id: XM_004863387   ⟹   XP_004863444
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,936,504 (-)NCBI
RefSeq Acc Id: XM_004863388   ⟹   XP_004863445
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,923,581 (-)NCBI
RefSeq Acc Id: XM_004863389   ⟹   XP_004863446
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,923,581 (-)NCBI
RefSeq Acc Id: XM_004863390   ⟹   XP_004863447
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,923,581 (-)NCBI
RefSeq Acc Id: XM_013064986   ⟹   XP_012920440
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,937,945 (-)NCBI
RefSeq Acc Id: XM_021243205   ⟹   XP_021098864
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,932,143 (-)NCBI
RefSeq Acc Id: XM_021243206   ⟹   XP_021098865
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248177,913,541 - 7,936,742 (-)NCBI
RefSeq Acc Id: XP_012920440   ⟸   XM_013064986
- Peptide Label: isoform X1
- UniProtKB: A0AAX6RP23 (UniProtKB/TrEMBL),   A0A0P6JMJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098865   ⟸   XM_021243206
- Peptide Label: isoform X1
- UniProtKB: A0AAX6RP23 (UniProtKB/TrEMBL),   A0A0P6JMJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863444   ⟸   XM_004863387
- Peptide Label: isoform X4
- UniProtKB: A0AAX6Q1S0 (UniProtKB/TrEMBL),   A0A0P6JMJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863442   ⟸   XM_004863385
- Peptide Label: isoform X2
- UniProtKB: A0AAX6Q144 (UniProtKB/TrEMBL),   A0A0P6JMJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863443   ⟸   XM_004863386
- Peptide Label: isoform X3
- UniProtKB: A0AAX6Q104 (UniProtKB/TrEMBL),   A0A0P6JMJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863441   ⟸   XM_004863384
- Peptide Label: isoform X1
- UniProtKB: A0AAX6RP23 (UniProtKB/TrEMBL),   A0A0P6JMJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098864   ⟸   XM_021243205
- Peptide Label: isoform X1
- UniProtKB: A0AAX6RP23 (UniProtKB/TrEMBL),   A0A0P6JMJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863447   ⟸   XM_004863390
- Peptide Label: isoform X7
- UniProtKB: A0AAX6Q1M2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863446   ⟸   XM_004863389
- Peptide Label: isoform X6
- UniProtKB: A0AAX6Q1V9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004863445   ⟸   XM_004863388
- Peptide Label: isoform X5
- UniProtKB: A0AAX6PZ24 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000014589   ⟸   ENSHGLT00000014734
Ensembl Acc Id: ENSHGLP00000014588   ⟸   ENSHGLT00000014733
Ensembl Acc Id: ENSHGLP00000014591   ⟸   ENSHGLT00000014736
Ensembl Acc Id: ENSHGLP00000014590   ⟸   ENSHGLT00000014735


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010438 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014733 ENTREZGENE
  ENSHGLT00000014734 ENTREZGENE
  ENSHGLT00000014735 ENTREZGENE
Gene3D-CATH 2.20.70.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Fe65 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
NCBI Gene Apbb1 ENTREZGENE
PANTHER AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1 UniProtKB/TrEMBL
  PTHR14058 UniProtKB/TrEMBL
Pfam PF00397 UniProtKB/TrEMBL
  PID UniProtKB/TrEMBL
PROSITE PID UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
  SM00456 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF51045 UniProtKB/TrEMBL
UniProt A0A0P6JMJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PZ24 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6Q104 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6Q144 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6Q1M2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6Q1S0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6Q1V9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RP23 ENTREZGENE, UniProtKB/TrEMBL