Kcnab1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1) - Rat Genome Database

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Gene: Kcnab1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1) Heterocephalus glaber
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Symbol: Kcnab1
Name: potassium voltage-gated channel subfamily A regulatory beta subunit 1 (Ensembl:potassium voltage-gated channel subfamily A member regulatory beta subunit 1)
RGD ID: 18924804
Description: ENCODES a protein that exhibits molecular function inhibitor activity (ortholog); NADPH binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN diaphragm development (ortholog); heart development (ortholog); learning or memory (ortholog); ASSOCIATED WITH hypertension (ortholog); Hypoxia (ortholog); temporal lobe epilepsy (ortholog); FOUND IN axon (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel subfamily A member regulatory beta subunit 1; potassium voltage-gated channel, shaker-related subfamily, beta member 1; voltage-gated potassium channel subunit beta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473033,876,381 - 34,139,594 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473033,701,386 - 34,141,269 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnab1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473033,876,381 - 34,139,594 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473033,701,386 - 34,141,269 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KCNAB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383156,118,211 - 156,539,138 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3156,037,701 - 156,538,756 (+)EnsemblGRCh38hg38GRCh38
GRCh373155,838,337 - 156,256,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363157,321,031 - 157,739,621 (+)NCBINCBI36Build 36hg18NCBI36
Celera3154,260,612 - 154,680,263 (+)NCBICelera
Cytogenetic Map3q25.31NCBI
HuRef3153,234,046 - 153,652,872 (+)NCBIHuRef
CHM1_13155,801,446 - 156,218,577 (+)NCBICHM1_1
T2T-CHM13v2.03158,892,837 - 159,313,792 (+)NCBIT2T-CHM13v2.0
Kcnab1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39364,856,636 - 65,285,643 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl364,856,617 - 65,285,644 (+)EnsemblGRCm39 Ensembl
GRCm38364,949,212 - 65,378,225 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl364,949,196 - 65,378,223 (+)EnsemblGRCm38mm10GRCm38
MGSCv37364,913,565 - 65,182,141 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36365,197,313 - 65,466,148 (+)NCBIMGSCv36mm8
Celera365,250,341 - 65,520,213 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.15NCBI
Kcnab1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82151,446,975 - 151,913,636 (+)NCBIGRCr8
mRatBN7.22149,137,025 - 149,603,540 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2149,137,041 - 149,603,534 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2156,426,340 - 156,713,448 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02154,475,802 - 154,764,811 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02149,108,477 - 149,397,485 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02155,555,798 - 156,011,438 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2155,718,359 - 156,009,526 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02174,966,379 - 175,400,010 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42154,837,841 - 155,145,882 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12154,787,803 - 155,095,845 (+)NCBI
Celera2143,747,424 - 144,023,440 (+)NCBICelera
Cytogenetic Map2q31NCBI
Kcnab1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554487,309,717 - 7,551,432 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554487,145,471 - 7,553,090 (+)NCBIChiLan1.0ChiLan1.0
KCNAB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22154,037,335 - 154,456,298 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13154,042,066 - 154,461,029 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03153,175,465 - 153,594,375 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13161,251,899 - 161,652,520 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3161,402,134 - 161,651,524 (+)Ensemblpanpan1.1panPan2
KCNAB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12349,775,790 - 50,135,372 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2349,776,089 - 50,133,707 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2349,650,372 - 50,009,284 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02350,409,624 - 50,768,980 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2350,409,741 - 50,767,309 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12349,994,486 - 50,352,950 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02350,044,700 - 50,403,869 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02350,331,182 - 50,690,531 (+)NCBIUU_Cfam_GSD_1.0
Kcnab1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560286,180,048 - 86,493,647 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365193,354,987 - 3,553,181 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365193,354,001 - 3,553,904 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNAB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1395,959,378 - 96,375,856 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11395,981,820 - 96,375,089 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213104,321,510 - 104,480,018 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNAB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11534,223,250 - 34,467,924 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1534,221,890 - 34,468,001 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660416,840,145 - 7,225,966 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004834500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004834501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004834502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01001564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01001577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01007677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000027423   ⟹   ENSHGLP00000027182
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473033,876,381 - 34,139,594 (+)Ensembl
RefSeq Acc Id: XM_004834500   ⟹   XP_004834557
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473033,701,386 - 34,141,269 (+)NCBI
RefSeq Acc Id: XM_004834501   ⟹   XP_004834558
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473033,726,932 - 34,141,269 (+)NCBI
RefSeq Acc Id: XM_004834502   ⟹   XP_004834559
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473033,875,493 - 34,141,269 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004834557 (Get FASTA)   NCBI Sequence Viewer  
  XP_004834558 (Get FASTA)   NCBI Sequence Viewer  
  XP_004834559 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027182
  ENSHGLP00000058667
  ENSHGLP00100017869
GenBank Protein JAN95955 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004834557   ⟸   XM_004834500
- Peptide Label: isoform X1
- UniProtKB: A0AAX6NQ56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834558   ⟸   XM_004834501
- Peptide Label: isoform X2
- UniProtKB: A0A0P6IVS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834559   ⟸   XM_004834502
- Peptide Label: isoform X3
- UniProtKB: A0AAX6NQ42 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000027182   ⟸   ENSHGLT00000027423


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019332 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100009527 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027423 ENTREZGENE
  ENSHGLT00000081130 UniProtKB/TrEMBL
  ENSHGLT00100018058 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.100 UniProtKB/TrEMBL
InterPro K_chnl_volt-dep_bsu_KCNAB UniProtKB/TrEMBL
  K_chnl_volt-dep_bsu_KCNAB-rel UniProtKB/TrEMBL
  K_chnl_volt-dep_bsu_KCNAB1 UniProtKB/TrEMBL
  NADP_OxRdtase_dom UniProtKB/TrEMBL
  NADP_OxRdtase_dom_sf UniProtKB/TrEMBL
NCBI Gene Kcnab1 ENTREZGENE
PANTHER PTHR43150 UniProtKB/TrEMBL
  VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT BETA-1 UniProtKB/TrEMBL
Pfam Aldo_ket_red UniProtKB/TrEMBL
PRINTS KCNAB1CHANEL UniProtKB/TrEMBL
  KCNABCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF51430 UniProtKB/TrEMBL
UniProt A0A0P6IVS5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NQ42 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NQ56 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-04-27 Kcnab1  potassium voltage-gated channel subfamily A regulatory beta subunit 1  Kcnab1  potassium voltage-gated channel subfamily A member regulatory beta subunit 1  Symbol and/or name change 5135510 APPROVED