Dnd1 (DND microRNA-mediated repression inhibitor 1) - Rat Genome Database

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Gene: Dnd1 (DND microRNA-mediated repression inhibitor 1) Heterocephalus glaber
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Symbol: Dnd1
Name: DND microRNA-mediated repression inhibitor 1
RGD ID: 18916526
Description: ENCODES a protein that exhibits miRNA binding (ortholog); mRNA 3'-UTR binding (ortholog); mRNA binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); germ cell development (ortholog); negative regulation of miRNA-mediated gene silencing (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 31 (ortholog); familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dead end homolog 1; dead end protein homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,421,810 - 33,424,635 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,421,810 - 33,424,515 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dnd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,421,810 - 33,424,635 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,421,810 - 33,424,515 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,670,794 - 140,673,576 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,670,794 - 140,673,576 (-)EnsemblGRCh38hg38GRCh38
GRCh375140,050,379 - 140,053,161 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365140,030,565 - 140,033,355 (-)NCBINCBI36Build 36hg18NCBI36
Build 345140,030,565 - 140,033,355NCBI
Celera5136,127,128 - 136,129,918 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5135,195,622 - 135,198,412 (-)NCBIHuRef
CHM1_15139,483,630 - 139,486,420 (-)NCBICHM1_1
T2T-CHM13v2.05141,196,191 - 141,198,973 (-)NCBIT2T-CHM13v2.0
Dnd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,896,724 - 36,899,267 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,896,724 - 36,899,267 (-)EnsemblGRCm39 Ensembl
GRCm381836,763,671 - 36,766,214 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,763,671 - 36,766,214 (-)EnsemblGRCm38mm10GRCm38
MGSCv371836,923,325 - 36,925,868 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,889,645 - 36,892,188 (-)NCBIMGSCv36mm8
Celera1837,215,735 - 37,218,278 (-)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Dnd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,652,712 - 28,655,336 (-)NCBIGRCr8
mRatBN7.21828,378,692 - 28,381,316 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,378,692 - 28,381,316 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,505,841 - 28,508,465 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01829,267,915 - 29,270,539 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,603,143 - 28,605,767 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,608,588 - 29,611,212 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,608,588 - 29,611,212 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01829,312,395 - 29,315,019 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,464,691 - 29,467,315 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1828,099,244 - 28,101,868 (-)NCBICelera
Cytogenetic Map18p11NCBI
Dnd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541830,893 - 32,936 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541830,795 - 33,394 (+)NCBIChiLan1.0ChiLan1.0
DND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,928,635 - 135,931,488 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15134,068,186 - 134,071,155 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05136,035,464 - 136,038,524 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15142,151,441 - 142,154,262 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5142,151,441 - 142,154,262 (-)Ensemblpanpan1.1panPan2
DND1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,825,154 - 35,827,913 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,825,636 - 35,827,840 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,864,141 - 32,867,086 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,280,764 - 36,283,709 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,281,246 - 36,283,450 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1233,333,099 - 33,336,044 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,200,879 - 34,203,823 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,953,593 - 34,956,538 (-)NCBIUU_Cfam_GSD_1.0
Dnd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,001,258 - 152,003,846 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,607,906 - 9,609,965 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,607,678 - 9,610,245 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2142,384,532 - 142,387,199 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12142,384,526 - 142,387,407 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22148,328,709 - 148,331,639 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12343,304,482 - 43,307,479 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2343,304,976 - 43,307,209 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603434,577,251 - 34,580,051 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000013230   ⟹   ENSHGLP00000013093
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474333,421,810 - 33,424,635 (-)Ensembl
RefSeq Acc Id: XM_004841901   ⟹   XP_004841958
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,421,810 - 33,424,515 (-)NCBI
RefSeq Acc Id: XM_004841902   ⟹   XP_004841959
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,421,810 - 33,424,515 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004841958 (Get FASTA)   NCBI Sequence Viewer  
  XP_004841959 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000013093
RefSeq Acc Id: XP_004841959   ⟸   XM_004841902
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004841958   ⟸   XM_004841901
- Peptide Label: isoform X1
Ensembl Acc Id: ENSHGLP00000013093   ⟸   ENSHGLT00000013230


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009358 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000013230 ENTREZGENE
NCBI Gene Dnd1 ENTREZGENE
UniProt A0AAX6P1Z7_HETGA UniProtKB/TrEMBL
  A0AAX6P274_HETGA UniProtKB/TrEMBL