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Gene: Spen (spen family transcriptional repressor) Heterocephalus glaber
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Symbol: Spen
Name: spen family transcriptional repressor
RGD ID: 18916193
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); RNA polymerase II transcription factor binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription, DNA-templated (ortholog); positive regulation of neurogenesis (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); transcription repressor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: msx2-interacting protein; spen homolog, transcriptional regulator
Orthologs:
Homo sapiens (human) : SPEN (spen family transcriptional repressor)  HGNC  Alliance
Mus musculus (house mouse) : Spen (spen family transcription repressor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Spen (spen family transcriptional repressor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spen (spen family transcriptional repressor)
Pan paniscus (bonobo/pygmy chimpanzee) : SPEN (spen family transcriptional repressor)
Canis lupus familiaris (dog) : SPEN (spen family transcriptional repressor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spen (spen family transcriptional repressor)
Sus scrofa (pig) : SPEN (spen family transcriptional repressor)
Chlorocebus sabaeus (African green monkey) : SPEN (spen family transcriptional repressor)
more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position: No map positions available.


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More on Spen
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 18916193
Created: 2020-01-23
Species: Heterocephalus glaber
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.