Pwwp2a (PWWP domain containing 2A) - Rat Genome Database

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Gene: Pwwp2a (PWWP domain containing 2A) Heterocephalus glaber
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Symbol: Pwwp2a
Name: PWWP domain containing 2A
RGD ID: 18913089
Description: ENCODES a protein that exhibits histone binding (ortholog); methylated histone binding (ortholog); NuRD complex binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); positive regulation of transcription elongation by RNA polymerase II (ortholog); regulation of transcriptional start site selection at RNA polymerase II promoter (ortholog); FOUND IN chromocenter (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PWWP domain-containing protein 2A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473329,404,778 - 29,441,414 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473329,404,918 - 29,443,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromocenter  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Pwwp2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473329,404,778 - 29,441,414 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473329,404,918 - 29,443,674 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PWWP2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385160,044,316 - 160,119,450 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5160,061,801 - 160,119,450 (-)EnsemblGRCh38hg38GRCh38
GRCh375159,502,889 - 159,546,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365159,435,467 - 159,479,030 (-)NCBINCBI36Build 36hg18NCBI36
Celera5155,534,450 - 155,578,003 (-)NCBICelera
Cytogenetic Map5q33.3NCBI
HuRef5154,597,226 - 154,640,986 (-)NCBIHuRef
CHM1_15158,935,909 - 158,979,466 (-)NCBICHM1_1
T2T-CHM13v2.05160,572,113 - 160,648,036 (-)NCBIT2T-CHM13v2.0
Pwwp2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,566,881 - 43,613,248 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1143,572,825 - 43,612,318 (+)EnsemblGRCm39 Ensembl
GRCm381143,681,125 - 43,722,633 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,681,998 - 43,721,491 (+)EnsemblGRCm38mm10GRCm38
MGSCv371143,495,500 - 43,536,135 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361143,525,378 - 43,566,056 (+)NCBIMGSCv36mm8
Celera1148,308,136 - 48,348,710 (+)NCBICelera
Cytogenetic Map11B1.1NCBI
cM Map1125.81NCBI
Pwwp2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81028,654,272 - 28,696,693 (+)NCBIGRCr8
mRatBN7.21028,155,509 - 28,195,255 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1028,155,605 - 28,194,308 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1032,915,090 - 32,953,781 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0101,453,464 - 1,492,155 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01027,885,634 - 27,924,324 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01029,288,060 - 29,335,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1029,289,203 - 29,334,478 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01029,128,931 - 29,175,653 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41028,789,156 - 28,828,007 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11028,813,480 - 28,815,082 (+)NCBI
Celera1027,646,254 - 27,683,715 (+)NCBICelera
Cytogenetic Map10q21NCBI
Pwwp2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540814,025,964 - 14,051,149 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540814,007,982 - 14,051,149 (-)NCBIChiLan1.0ChiLan1.0
PWWP2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24155,247,172 - 155,304,599 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15153,386,720 - 153,443,973 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05155,452,698 - 155,509,961 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15162,083,726 - 162,126,580 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5162,085,988 - 162,130,604 (-)Ensemblpanpan1.1panPan2
PWWP2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1450,558,972 - 50,596,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha450,453,374 - 50,490,652 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0450,994,006 - 51,031,276 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl450,993,644 - 51,031,271 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1450,802,291 - 50,839,748 (+)NCBIUMICH_Zoey_3.1
UU_Cfam_GSD_1.0451,446,156 - 51,483,420 (+)NCBIUU_Cfam_GSD_1.0
Pwwp2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213104,949,993 - 104,986,924 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365153,399,339 - 3,436,003 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PWWP2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1663,409,932 - 63,448,871 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11663,409,898 - 63,449,997 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21668,901,249 - 68,940,242 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PWWP2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12362,428,936 - 62,490,904 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2362,460,139 - 62,490,803 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603415,116,595 - 15,181,271 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000014684   ⟹   ENSHGLP00000014539
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473329,404,778 - 29,441,414 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000014685   ⟹   ENSHGLP00000014540
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473329,405,024 - 29,429,101 (+)Ensembl
RefSeq Acc Id: XM_004836457   ⟹   XP_004836514
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,918 - 29,431,978 (+)NCBI
RefSeq Acc Id: XM_004836458   ⟹   XP_004836515
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,923 - 29,443,674 (+)NCBI
RefSeq Acc Id: XM_004836459   ⟹   XP_004836516
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,923 - 29,443,674 (+)NCBI
RefSeq Acc Id: XM_004836460   ⟹   XP_004836517
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,924 - 29,443,674 (+)NCBI
RefSeq Acc Id: XM_004836465   ⟹   XP_004836522
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,923 - 29,443,674 (+)NCBI
RefSeq Acc Id: XM_021240349   ⟹   XP_021096008
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,405,509 - 29,431,488 (+)NCBI
RefSeq Acc Id: XM_021240358   ⟹   XP_021096017
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,923 - 29,431,976 (+)NCBI
RefSeq Acc Id: XR_002387738
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,918 - 29,440,333 (+)NCBI
RefSeq Acc Id: XR_002387742
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,922 - 29,443,674 (+)NCBI
RefSeq Acc Id: XR_002387743
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,922 - 29,440,488 (+)NCBI
RefSeq Acc Id: XR_002387744
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,923 - 29,440,332 (+)NCBI
RefSeq Acc Id: XR_002387745
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,923 - 29,438,579 (+)NCBI
RefSeq Acc Id: XR_204814
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473329,404,922 - 29,440,332 (+)NCBI
RefSeq Acc Id: XP_004836514   ⟸   XM_004836457
- Peptide Label: isoform X1
- UniProtKB: A0AAX6NTE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836516   ⟸   XM_004836459
- Peptide Label: isoform X3
- UniProtKB: A0AAX6NTE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836515   ⟸   XM_004836458
- Peptide Label: isoform X2
- UniProtKB: A0AAX6NTF0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836522   ⟸   XM_004836465
- Peptide Label: isoform X7
- UniProtKB: A0AAX6NTG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021096017   ⟸   XM_021240358
- Peptide Label: isoform X6
- UniProtKB: A0AAX6RHC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004836517   ⟸   XM_004836460
- Peptide Label: isoform X4
- UniProtKB: A0AAX6NTF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021096008   ⟸   XM_021240349
- Peptide Label: isoform X5
- UniProtKB: A0AAX6RI64 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000014539   ⟸   ENSHGLT00000014684
Ensembl Acc Id: ENSHGLP00000014540   ⟸   ENSHGLT00000014685


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010411 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014684 ENTREZGENE
Gene3D-CATH 2.30.30.140 UniProtKB/TrEMBL
InterPro PWWP_dom UniProtKB/TrEMBL
NCBI Gene Pwwp2a ENTREZGENE
PANTHER METHYL-CPG BINDING PROTEIN, DROSOPHILA UniProtKB/TrEMBL
  PWWP DOMAIN-CONTAINING 2B UniProtKB/TrEMBL
Pfam PWWP UniProtKB/TrEMBL
PROSITE PWWP UniProtKB/TrEMBL
SMART PWWP UniProtKB/TrEMBL
Superfamily-SCOP Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt A0AAX6NTE6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTE9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTF0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTF2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NTG6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RHC8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RI64 ENTREZGENE, UniProtKB/TrEMBL