Ncoa2 (nuclear receptor coactivator 2) - Rat Genome Database

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Gene: Ncoa2 (nuclear receptor coactivator 2) Heterocephalus glaber
Analyze
Symbol: Ncoa2
Name: nuclear receptor coactivator 2
RGD ID: 18912440
Description: ENCODES a protein that exhibits aryl hydrocarbon receptor binding (ortholog); chromatin binding (ortholog); DNA polymerase binding (ortholog); INVOLVED IN cellular response to Thyroglobulin triiodothyronine (ortholog); cerebellum development (ortholog); circadian regulation of gene expression (ortholog); PARTICIPATES IN aldosterone signaling pathway; altered androgen signaling pathway; androgen signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Breast Neoplasms (ortholog); Chronobiology Disorders (ortholog); FOUND IN cytoplasm (ortholog); dendritic spine (ortholog); nuclear body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474420,938,555 - 21,078,690 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474420,795,385 - 21,078,706 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ncoa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474420,938,555 - 21,078,690 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474420,795,385 - 21,078,706 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NCOA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38870,109,782 - 70,456,446 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl870,109,782 - 70,403,808 (-)EnsemblGRCh38hg38GRCh38
GRCh37871,022,017 - 71,316,452 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36871,186,821 - 71,478,574 (-)NCBINCBI36Build 36hg18NCBI36
Build 34871,186,820 - 71,478,574NCBI
Celera867,021,935 - 67,313,703 (-)NCBICelera
Cytogenetic Map8q13.3NCBI
HuRef866,517,566 - 66,809,329 (-)NCBIHuRef
CHM1_1871,079,808 - 71,371,655 (-)NCBICHM1_1
T2T-CHM13v2.0870,539,621 - 70,834,144 (-)NCBIT2T-CHM13v2.0
Ncoa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,209,329 - 13,444,451 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,209,329 - 13,444,307 (-)EnsemblGRCm39 Ensembl
GRCm38113,139,105 - 13,374,227 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,139,105 - 13,374,083 (-)EnsemblGRCm38mm10GRCm38
MGSCv37113,129,240 - 13,364,164 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,127,689 - 13,359,278 (-)NCBIMGSCv36mm8
Celera113,103,226 - 13,334,430 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.12NCBI
Ncoa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8510,618,712 - 10,852,776 (+)NCBIGRCr8
mRatBN7.255,835,642 - 6,069,693 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl55,835,706 - 6,067,451 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx58,132,076 - 8,209,657 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.059,770,968 - 9,848,544 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.059,460,403 - 9,538,097 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.055,466,544 - 5,696,540 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl55,616,483 - 5,694,598 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0510,306,581 - 10,538,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.455,197,891 - 5,275,776 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.155,197,890 - 5,273,000 (+)NCBI
Celera55,570,901 - 5,648,759 (+)NCBICelera
Cytogenetic Map5q11NCBI
Ncoa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554449,313,447 - 9,584,913 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554449,313,748 - 9,587,109 (+)NCBIChiLan1.0ChiLan1.0
NCOA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2785,839,497 - 86,141,138 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1861,469,337 - 61,770,965 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0866,632,139 - 66,929,526 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1868,293,012 - 68,480,104 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl868,293,018 - 68,400,479 (-)Ensemblpanpan1.1panPan2
NCOA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12919,253,849 - 19,471,640 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2919,222,842 - 19,545,371 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2919,511,986 - 19,805,562 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02919,347,144 - 19,643,120 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2919,347,185 - 19,642,297 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12919,386,646 - 19,682,493 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02919,452,837 - 19,748,399 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02919,733,575 - 20,029,399 (-)NCBIUU_Cfam_GSD_1.0
Ncoa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530359,680,707 - 59,940,562 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649614,844,855 - 15,016,454 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649614,844,923 - 15,102,922 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCOA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl464,954,238 - 65,246,572 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1464,888,029 - 65,245,757 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2470,584,741 - 70,791,313 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NCOA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1865,855,232 - 66,151,733 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl865,855,235 - 66,040,947 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603975,279,759 - 75,586,607 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004842063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004842065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004842066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004842067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013071225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013071226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021256032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01023559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01023567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01005955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000023508   ⟹   ENSHGLP00000023292
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474420,938,555 - 21,078,690 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000023509   ⟹   ENSHGLP00000023293
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474420,971,930 - 21,078,690 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000023510   ⟹   ENSHGLP00000023294
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474420,971,930 - 21,066,427 (+)Ensembl
RefSeq Acc Id: XM_004842063   ⟹   XP_004842120
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,795,395 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_004842065   ⟹   XP_004842122
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,938,566 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_004842066   ⟹   XP_004842123
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,795,385 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_004842067   ⟹   XP_004842124
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,795,395 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_013071225   ⟹   XP_012926679
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,890,213 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_013071226   ⟹   XP_012926680
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,795,813 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_021256029   ⟹   XP_021111688
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,797,094 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_021256030   ⟹   XP_021111689
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,867,488 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_021256031   ⟹   XP_021111690
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474420,869,561 - 21,078,706 (+)NCBI
RefSeq Acc Id: XM_021256032   ⟹   XP_021111691
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474421,010,701 - 21,078,706 (+)NCBI
RefSeq Acc Id: XP_004842123   ⟸   XM_004842066
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ESX6 (UniProtKB/TrEMBL),   G5BGR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842120   ⟸   XM_004842063
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ESX6 (UniProtKB/TrEMBL),   G5BGR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842124   ⟸   XM_004842067
- Peptide Label: isoform X2
- UniProtKB: G5BGR4 (UniProtKB/TrEMBL),   A0AAX6P2J6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926680   ⟸   XM_013071226
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ESX6 (UniProtKB/TrEMBL),   G5BGR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111688   ⟸   XM_021256029
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ESX6 (UniProtKB/TrEMBL),   G5BGR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111689   ⟸   XM_021256030
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ESX6 (UniProtKB/TrEMBL),   G5BGR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111690   ⟸   XM_021256031
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ESX6 (UniProtKB/TrEMBL),   G5BGR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926679   ⟸   XM_013071225
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ESX6 (UniProtKB/TrEMBL),   G5BGR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842122   ⟸   XM_004842065
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ESX6 (UniProtKB/TrEMBL),   G5BGR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111691   ⟸   XM_021256032
- Peptide Label: isoform X3
- UniProtKB: G5BGR4 (UniProtKB/TrEMBL),   A0AAX6SPW5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000023294   ⟸   ENSHGLT00000023510
Ensembl Acc Id: ENSHGLP00000023293   ⟸   ENSHGLT00000023509
Ensembl Acc Id: ENSHGLP00000023292   ⟸   ENSHGLT00000023508


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016603 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023508 ENTREZGENE
  ENSHGLT00000023509 ENTREZGENE
  ENSHGLT00000023510 ENTREZGENE
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  6.10.140.20 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  DUF4927 UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  NCO_DUF1518 UniProtKB/TrEMBL
  NCOA2 UniProtKB/TrEMBL
  Nuc_rcpt_coact UniProtKB/TrEMBL
  Nuc_rcpt_coact_Ncoa-typ UniProtKB/TrEMBL
  Nuc_rcpt_coact_Ncoa_int_sf UniProtKB/TrEMBL
  Nuclear_rcpt_coactivator UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
  SRC/p160_LXXLL UniProtKB/TrEMBL
KEGG Report hgl:101700727 UniProtKB/TrEMBL
NCBI Gene Ncoa2 ENTREZGENE
PANTHER PTHR10684 UniProtKB/TrEMBL
  PTHR10684:SF2 UniProtKB/TrEMBL
Pfam DUF1518 UniProtKB/TrEMBL
  DUF4927 UniProtKB/TrEMBL
  NCOA_u2 UniProtKB/TrEMBL
  Nuc_rec_co-act UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS_11 UniProtKB/TrEMBL
  SRC-1 UniProtKB/TrEMBL
PIRSF Nuclear_receptor_coactivator UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART DUF1518 UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
  SSF69125 UniProtKB/TrEMBL
UniProt A0A0N8ESX6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6P2J6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SPW5 ENTREZGENE, UniProtKB/TrEMBL
  G5BGR4 ENTREZGENE, UniProtKB/TrEMBL