Nup153 (nucleoporin 153) - Rat Genome Database

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Gene: Nup153 (nucleoporin 153) Heterocephalus glaber
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Symbol: Nup153
Name: nucleoporin 153
RGD ID: 18912105
Description: ENCODES a protein that exhibits chromatin binding (ortholog); double-stranded DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN amyloid fibril formation (ortholog); negative regulation of RNA export from nucleus (ortholog); nuclear pore complex assembly (ortholog); PARTICIPATES IN mRNA nuclear export pathway; ASSOCIATED WITH Pulmonary Atresia (ortholog); FOUND IN annulate lamellae (ortholog); cytosol (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear pore complex protein Nup153
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247568,889,992 - 8,959,115 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247568,890,010 - 8,959,704 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Nup153
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247568,889,992 - 8,959,115 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247568,890,010 - 8,959,704 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NUP153
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38617,615,037 - 17,706,925 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl617,615,035 - 17,706,925 (-)EnsemblGRCh38hg38GRCh38
GRCh37617,615,268 - 17,707,156 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36617,723,248 - 17,814,797 (-)NCBINCBI36Build 36hg18NCBI36
Build 34617,723,247 - 17,814,797NCBI
Celera618,853,298 - 18,944,916 (-)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef617,559,859 - 17,651,999 (-)NCBIHuRef
CHM1_1617,617,771 - 17,709,603 (-)NCBICHM1_1
T2T-CHM13v2.0617,487,223 - 17,579,176 (-)NCBIT2T-CHM13v2.0
Nup153
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391346,833,369 - 46,890,682 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1346,833,381 - 46,881,416 (-)EnsemblGRCm39 Ensembl
GRCm381346,679,902 - 46,727,849 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1346,679,905 - 46,727,940 (-)EnsemblGRCm38mm10GRCm38
MGSCv371346,775,271 - 46,823,218 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361346,691,073 - 46,738,559 (-)NCBIMGSCv36mm8
Celera1347,763,419 - 47,811,332 (-)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1324.3NCBI
Nup153
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81718,178,434 - 18,231,109 (+)NCBIGRCr8
mRatBN7.21717,972,217 - 18,024,876 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1717,972,217 - 18,024,876 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1717,858,346 - 17,910,897 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01719,462,206 - 19,514,765 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01717,785,461 - 17,838,024 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01718,358,712 - 18,411,368 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1718,358,712 - 18,411,368 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01719,523,818 - 19,576,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41724,031,666 - 24,084,210 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11724,034,506 - 24,086,843 (+)NCBI
Celera1717,680,974 - 17,733,501 (+)NCBICelera
Cytogenetic Map17p14NCBI
Nup153
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554838,388,066 - 8,455,965 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554838,377,253 - 8,457,018 (+)NCBIChiLan1.0ChiLan1.0
NUP153
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2532,280,305 - 32,372,958 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1628,265,350 - 28,357,856 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0617,468,826 - 17,561,064 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1617,826,769 - 17,918,060 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl617,826,769 - 17,917,992 (-)Ensemblpanpan1.1panPan2
NUP153
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13516,517,992 - 16,598,472 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3516,519,109 - 16,589,537 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3516,468,185 - 16,540,246 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03516,624,199 - 16,708,905 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3516,624,201 - 16,696,283 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13516,438,735 - 16,523,130 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03516,492,051 - 16,576,640 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03517,825,780 - 17,910,231 (-)NCBIUU_Cfam_GSD_1.0
Nup153
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049468,133,301 - 8,201,435 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365523,530,559 - 3,577,177 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365523,529,506 - 3,588,830 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUP153
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl713,393,547 - 13,466,504 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1713,393,542 - 13,466,577 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2714,095,848 - 14,184,559 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUP153
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11754,426,383 - 54,518,986 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1754,426,289 - 54,519,249 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604417,820,600 - 17,921,055 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000011167   ⟹   ENSHGLP00000011043
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247568,889,992 - 8,959,115 (+)Ensembl
RefSeq Acc Id: XM_004847632   ⟹   XP_004847689
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247568,890,010 - 8,959,704 (+)NCBI
RefSeq Acc Id: XM_004847633   ⟹   XP_004847690
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247568,892,213 - 8,959,704 (+)NCBI
RefSeq Acc Id: XM_004847635   ⟹   XP_004847692
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247568,890,010 - 8,959,704 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004847689 (Get FASTA)   NCBI Sequence Viewer  
  XP_004847690 (Get FASTA)   NCBI Sequence Viewer  
  XP_004847692 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011043
RefSeq Acc Id: XP_004847689   ⟸   XM_004847632
- Peptide Label: isoform X1
- UniProtKB: G5AXT4 (UniProtKB/TrEMBL),   A0AAX6PBT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004847692   ⟸   XM_004847635
- Peptide Label: isoform X3
- UniProtKB: G5AXT4 (UniProtKB/TrEMBL),   A0AAX6PAJ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004847690   ⟸   XM_004847633
- Peptide Label: isoform X2
- UniProtKB: G5AXT4 (UniProtKB/TrEMBL),   A0AAX6PBL8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000011043   ⟸   ENSHGLT00000011167


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007924 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011167 ENTREZGENE
Gene3D-CATH Zinc finger, RanBP2-type UniProtKB/TrEMBL
InterPro Nucleoporin UniProtKB/TrEMBL
  Nup153_N UniProtKB/TrEMBL
  Retro-transposon_transp_CS UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
NCBI Gene Nup153 ENTREZGENE
PANTHER NUCLEAR PORE COMPLEX PROTEIN NUP UniProtKB/TrEMBL
  NUCLEAR PORE COMPLEX PROTEIN NUP153 UniProtKB/TrEMBL
Pfam Nup153 UniProtKB/TrEMBL
  Nup_retrotrp_bd UniProtKB/TrEMBL
  zf-RanBP UniProtKB/TrEMBL
PROSITE ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
SMART ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP Ran binding protein zinc finger-like UniProtKB/TrEMBL
UniProt A0AAX6PAJ9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PBL8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PBT3 ENTREZGENE, UniProtKB/TrEMBL
  G5AXT4 ENTREZGENE, UniProtKB/TrEMBL