Chrm3 (cholinergic receptor muscarinic 3) - Rat Genome Database

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Gene: Chrm3 (cholinergic receptor muscarinic 3) Heterocephalus glaber
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Symbol: Chrm3
Name: cholinergic receptor muscarinic 3
RGD ID: 18908956
Description: ENCODES a protein that exhibits acetylcholine binding (ortholog); G protein-coupled acetylcholine receptor activity (ortholog); G protein-coupled acetylcholine receptor binding (ortholog); INVOLVED IN acetylcholine receptor signaling pathway (ortholog); calcium-mediated signaling (ortholog); G protein-coupled acetylcholine receptor signaling pathway (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; ASSOCIATED WITH Ascites (ortholog); asthma (ortholog); bladder disease (ortholog); FOUND IN asymmetric synapse (ortholog); axon terminus (ortholog); basal plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Muscarinic acetylcholine receptor M3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477510,949,983 - 10,951,755 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477510,948,075 - 11,427,898 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Chrm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477510,949,983 - 10,951,755 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477510,948,075 - 11,427,898 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CHRM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381239,386,568 - 239,915,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1239,386,565 - 239,915,452 (+)EnsemblGRCh38hg38GRCh38
GRCh371239,549,868 - 240,078,750 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361237,858,996 - 238,139,343 (+)NCBINCBI36Build 36hg18NCBI36
Build 341236,118,413 - 236,398,756NCBI
Celera1213,047,986 - 213,328,202 (+)NCBICelera
Cytogenetic Map1q43NCBI
HuRef1210,250,783 - 210,531,551 (+)NCBIHuRef
CHM1_11241,065,995 - 241,346,299 (+)NCBICHM1_1
T2T-CHM13v2.01238,798,998 - 239,328,607 (+)NCBIT2T-CHM13v2.0
Chrm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39139,925,522 - 10,411,131 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl139,925,522 - 10,410,883 (-)EnsemblGRCm39 Ensembl
GRCm38139,875,486 - 10,361,062 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl139,875,486 - 10,360,847 (-)EnsemblGRCm38mm10GRCm38
MGSCv37139,875,859 - 10,360,049 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36139,875,859 - 10,360,049 (-)NCBIMGSCv36mm8
Celera139,820,205 - 10,316,018 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map133.72NCBI
Chrm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81764,696,549 - 65,158,622 (+)NCBIGRCr8
mRatBN7.21760,005,137 - 60,467,250 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1760,005,202 - 60,467,278 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1763,209,233 - 63,671,688 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01767,212,340 - 67,674,776 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01761,366,663 - 61,834,600 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01763,990,599 - 64,463,222 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1763,990,599 - 63,994,169 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01765,753,665 - 66,217,211 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41771,214,906 - 71,218,463 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11771,081,449 - 71,229,296 (+)NCBI
Celera1760,109,356 - 60,562,246 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
Chrm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955492958,949 - 960,721 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955492958,347 - 1,429,832 (-)NCBIChiLan1.0ChiLan1.0
CHRM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v219,253,466 - 9,776,967 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan119,478,692 - 10,000,031 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01214,931,514 - 215,452,739 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11219,927,079 - 220,446,830 (+)NCBIpanpan1.1PanPan1.1panPan2
CHRM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.14504,663 - 999,550 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl4506,990 - 520,613 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha4547,625 - 1,042,706 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.04528,395 - 1,026,611 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl4529,298 - 1,025,023 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.14522,413 - 1,023,728 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.04628,064 - 1,134,213 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.04882,752 - 1,377,924 (-)NCBIUU_Cfam_GSD_1.0
Chrm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934437,787,915 - 38,208,967 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648413,954,887 - 13,956,659 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648413,953,141 - 14,373,174 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,828,231 - 51,830,003 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,818,625 - 52,363,662 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21455,361,402 - 55,363,168 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHRM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12576,772,212 - 77,009,433 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2577,001,477 - 77,003,249 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605578,598,053 - 79,113,674 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000029066   ⟹   ENSHGLP00000028550
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477510,949,983 - 10,951,755 (-)Ensembl
RefSeq Acc Id: XM_004854597   ⟹   XP_004854654
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477510,948,075 - 11,427,898 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004854654 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16914 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000028550
GenBank Protein JAN99066 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004854654   ⟸   XM_004854597
- UniProtKB: G5C5V3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000028550   ⟸   ENSHGLT00000029066


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000020856 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000029066 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Musac_Ach_M3_rcpt UniProtKB/TrEMBL
  Musac_Ach_rcpt UniProtKB/TrEMBL
KEGG Report hgl:101718361 UniProtKB/TrEMBL
NCBI Gene Chrm3 ENTREZGENE
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR UniProtKB/TrEMBL
  MUSCARINIC ACETYLCHOLINE RECEPTOR M3 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  MUSCARINICR UniProtKB/TrEMBL
  MUSCRINICM3R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt G5C5V3 ENTREZGENE, UniProtKB/TrEMBL