Kel (Kell metallo-endopeptidase (Kell blood group)) - Rat Genome Database

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Gene: Kel (Kell metallo-endopeptidase (Kell blood group)) Heterocephalus glaber
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Symbol: Kel
Name: Kell metallo-endopeptidase (Kell blood group)
RGD ID: 18908886
Description: ENCODES a protein that exhibits metal ion binding (inferred); metalloendopeptidase activity (inferred); metallopeptidase activity (inferred); INVOLVED IN establishment of localization in cell (ortholog); intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); ASSOCIATED WITH hemolytic disease of the fetus (ortholog); Vein of Galen Aneurysm (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kell blood group glycoprotein; Kell blood group, metallo-endopeptidase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480011,870,759 - 11,894,190 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480011,871,226 - 11,892,584 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kel
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480011,870,759 - 11,894,190 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480011,871,226 - 11,892,584 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KEL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387142,941,114 - 142,962,363 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7142,941,114 - 142,962,363 (-)EnsemblGRCh38hg38GRCh38
GRCh377142,638,201 - 142,659,450 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367142,348,323 - 142,369,625 (-)NCBINCBI36Build 36hg18NCBI36
Build 347142,155,039 - 142,176,340NCBI
Celera7137,475,061 - 137,496,363 (-)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7136,976,490 - 136,997,792 (-)NCBIHuRef
CHM1_17142,575,086 - 142,596,388 (-)NCBICHM1_1
T2T-CHM13v2.07144,296,525 - 144,394,915 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27142,040,072 - 142,061,375 (-)NCBI
Kel
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39641,663,263 - 41,681,268 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl641,663,264 - 41,681,273 (-)EnsemblGRCm39 Ensembl
GRCm38641,686,329 - 41,704,334 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl641,686,330 - 41,704,339 (-)EnsemblGRCm38mm10GRCm38
MGSCv37641,636,329 - 41,654,324 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36641,615,942 - 41,633,896 (-)NCBIMGSCv36mm8
Celera641,638,913 - 41,656,912 (-)NCBICelera
Cytogenetic Map6B2.1NCBI
cM Map619.86NCBI
Kel
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8471,534,882 - 71,552,297 (-)NCBIGRCr8
mRatBN7.2470,568,241 - 70,585,666 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl470,568,243 - 70,585,631 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx475,485,787 - 75,502,670 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0471,399,042 - 71,415,925 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0469,807,241 - 69,824,134 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0470,979,504 - 70,996,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl470,979,504 - 70,996,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04135,766,569 - 135,783,987 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4469,392,846 - 69,409,737 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera465,533,172 - 65,550,063 (-)NCBICelera
Cytogenetic Map4q23NCBI
Kel
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955494668,798 - 688,079 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955494668,188 - 688,036 (+)NCBIChiLan1.0ChiLan1.0
LOC100989368
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26179,752,428 - 180,141,077 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1731,762,687 - 31,860,321 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07134,897,567 - 135,237,214 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17147,422,965 - 147,444,255 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7147,423,103 - 147,443,895 (-)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl7147,389,844 - 147,415,404 (-)Ensemblpanpan1.1panPan2
KEL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1166,396,724 - 6,645,221 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl166,623,824 - 6,645,094 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,535,089 - 7,558,835 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,250,137 - 6,556,234 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,536,981 - 6,556,219 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,197,531 - 6,509,648 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,049,436 - 6,361,088 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,124,842 - 6,419,811 (+)NCBIUU_Cfam_GSD_1.0
Kel
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511812,477,820 - 12,497,394 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936527406,132 - 427,186 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936527406,061 - 431,142 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KEL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,259,144 - 7,279,328 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,242,378 - 7,279,345 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2187,555,045 - 7,594,117 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KEL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121111,819,230 - 111,846,966 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21111,819,368 - 111,840,142 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660728,542,852 - 8,567,980 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000021906   ⟹   ENSHGLP00000021696
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462480011,870,759 - 11,894,190 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000021907   ⟹   ENSHGLP00000021697
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462480011,870,759 - 11,894,190 (+)Ensembl
RefSeq Acc Id: XM_004860508   ⟹   XP_004860565
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480011,871,242 - 11,892,584 (+)NCBI
RefSeq Acc Id: XM_004860510   ⟹   XP_004860567
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480011,871,240 - 11,892,584 (+)NCBI
RefSeq Acc Id: XM_004860511   ⟹   XP_004860568
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480011,871,238 - 11,892,584 (+)NCBI
RefSeq Acc Id: XM_021240931   ⟹   XP_021096590
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480011,871,242 - 11,892,584 (+)NCBI
RefSeq Acc Id: XR_002388082
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480011,871,226 - 11,891,136 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004860565 (Get FASTA)   NCBI Sequence Viewer  
  XP_004860567 (Get FASTA)   NCBI Sequence Viewer  
  XP_004860568 (Get FASTA)   NCBI Sequence Viewer  
  XP_021096590 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021697
RefSeq Acc Id: XP_004860568   ⟸   XM_004860511
- Peptide Label: isoform X4
- UniProtKB: A0AAX6PVW9 (UniProtKB/TrEMBL),   G5C2L2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860567   ⟸   XM_004860510
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PVH1 (UniProtKB/TrEMBL),   G5C2L2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860565   ⟸   XM_004860508
- Peptide Label: isoform X1
- UniProtKB: A0AAX6PVN6 (UniProtKB/TrEMBL),   G5C2L2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021096590   ⟸   XM_021240931
- Peptide Label: isoform X3
- UniProtKB: A0AAX6RKQ5 (UniProtKB/TrEMBL),   G5C2L2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000021697   ⟸   ENSHGLT00000021907
Ensembl Acc Id: ENSHGLP00000021696   ⟸   ENSHGLT00000021906


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015502 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000021907 ENTREZGENE
Gene3D-CATH Neutral endopeptidase , domain2 UniProtKB/TrEMBL
InterPro Peptidase_M13 UniProtKB/TrEMBL
  Peptidase_M13_C UniProtKB/TrEMBL
  Peptidase_M13_dom_2 UniProtKB/TrEMBL
  Peptidase_M13_N UniProtKB/TrEMBL
NCBI Gene Kel ENTREZGENE
PANTHER KELL BLOOD GROUP GLYCOPROTEIN UniProtKB/TrEMBL
  ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED UniProtKB/TrEMBL
Pfam Peptidase_M13 UniProtKB/TrEMBL
  Peptidase_M13_N UniProtKB/TrEMBL
PROSITE NEPRILYSIN UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
UniProt A0AAX6PVH1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PVN6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PVW9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RKQ5 ENTREZGENE, UniProtKB/TrEMBL
  G5C2L2 ENTREZGENE, UniProtKB/TrEMBL