C1qa (complement C1q A chain) - Rat Genome Database

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Gene: C1qa (complement C1q A chain) Heterocephalus glaber
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Symbol: C1qa
Name: complement C1q A chain
RGD ID: 18901903
Description: INVOLVED IN astrocyte activation (ortholog); complement activation, classical pathway (ortholog); complement-mediated synapse pruning (ortholog); ASSOCIATED WITH 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ortholog); basal cell carcinoma (ortholog); Brain Injuries (ortholog); FOUND IN complement component C1q complex (ortholog); extrinsic component of postsynaptic membrane (ortholog); extrinsic component of presynaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: complement C1q subcomponent subunit A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247647,363,567 - 7,366,617 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247647,363,615 - 7,366,408 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
C1qa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247647,363,567 - 7,366,617 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247647,363,615 - 7,366,408 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
C1QA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38122,636,463 - 22,639,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl122,635,077 - 22,639,678 (+)EnsemblGRCh38hg38GRCh38
GRCh37122,962,956 - 22,966,171 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,835,705 - 22,838,762 (+)NCBINCBI36Build 36hg18NCBI36
Build 34122,709,405 - 22,711,405NCBI
Celera121,287,826 - 21,290,883 (+)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef121,207,463 - 21,210,520 (+)NCBIHuRef
CHM1_1123,075,637 - 23,078,694 (+)NCBICHM1_1
T2T-CHM13v2.0122,461,488 - 22,464,703 (+)NCBIT2T-CHM13v2.0
C1qa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394136,623,227 - 136,626,155 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4136,623,228 - 136,626,114 (-)EnsemblGRCm39 Ensembl
GRCm384136,895,916 - 136,898,844 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4136,895,917 - 136,898,803 (-)EnsemblGRCm38mm10GRCm38
MGSCv374136,451,831 - 136,454,759 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364136,167,994 - 136,170,836 (-)NCBIMGSCv36mm8
Celera4135,103,233 - 135,106,157 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map469.05NCBI
C1qa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85154,417,086 - 154,419,933 (-)NCBIGRCr8
mRatBN7.25149,133,635 - 149,136,482 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5149,133,636 - 149,136,534 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5151,831,406 - 151,834,253 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05153,605,693 - 153,608,540 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05153,587,691 - 153,590,538 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05155,261,254 - 155,264,101 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5155,261,250 - 155,264,143 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05159,023,753 - 159,026,600 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45155,662,333 - 155,665,180 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15155,672,371 - 155,675,219 (-)NCBI
Celera5147,531,382 - 147,534,229 (-)NCBICelera
Cytogenetic Map5q36NCBI
C1qa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554522,752,970 - 2,756,488 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554522,753,362 - 2,756,220 (+)NCBIChiLan1.0ChiLan1.0
C1QA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21204,307,981 - 204,311,074 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11203,410,999 - 203,414,092 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0121,821,927 - 21,825,020 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1122,770,557 - 22,773,682 (+)NCBIpanpan1.1PanPan1.1panPan2
C1QA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1276,668,086 - 76,671,082 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl276,668,217 - 76,670,977 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha273,172,967 - 73,175,970 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0277,227,331 - 77,230,335 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl277,227,333 - 77,230,230 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,048,204 - 74,051,200 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,056,639 - 75,059,641 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0276,060,247 - 76,063,252 (-)NCBIUU_Cfam_GSD_1.0
C1qa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505842,183,130 - 42,185,545 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364748,008,534 - 8,010,191 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364748,007,953 - 8,010,591 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C1QA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl680,586,280 - 80,589,204 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1680,586,259 - 80,589,213 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2674,610,025 - 74,612,855 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C1QA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120110,024,847 - 110,027,868 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660336,286,037 - 6,289,144 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000015559   ⟹   ENSHGLP00000015399
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247647,363,567 - 7,366,617 (+)Ensembl
RefSeq Acc Id: XM_004850533   ⟹   XP_004850590
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247647,363,825 - 7,366,408 (+)NCBI
RefSeq Acc Id: XM_004850534   ⟹   XP_004850591
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247647,363,615 - 7,366,408 (+)NCBI
RefSeq Acc Id: XM_004850535   ⟹   XP_004850592
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247647,363,615 - 7,366,408 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004850590 (Get FASTA)   NCBI Sequence Viewer  
  XP_004850591 (Get FASTA)   NCBI Sequence Viewer  
  XP_004850592 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015399
GenBank Protein JAO00161 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004850592   ⟸   XM_004850535
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JW15 (UniProtKB/TrEMBL),   G5BHZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004850591   ⟸   XM_004850534
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JW15 (UniProtKB/TrEMBL),   G5BHZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004850590   ⟸   XM_004850533
- Peptide Label: isoform X1
- UniProtKB: A0AAX6PEQ6 (UniProtKB/TrEMBL),   G5BHZ8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000015399   ⟸   ENSHGLT00000015559


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011009 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000015559 ENTREZGENE
Gene3D-CATH 2.60.120.40 UniProtKB/TrEMBL
InterPro C1q_dom UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
  Collagen/C1q_domain UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/TrEMBL
NCBI Gene C1qa ENTREZGENE
PANTHER EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER UniProtKB/TrEMBL
  PTHR15427:SF26 UniProtKB/TrEMBL
Pfam C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
PRINTS COMPLEMNTC1Q UniProtKB/TrEMBL
PROSITE C1Q UniProtKB/TrEMBL
SMART C1Q UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/TrEMBL
UniProt A0A0P6JW15 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PEQ6 ENTREZGENE, UniProtKB/TrEMBL
  G5BHZ8 ENTREZGENE, UniProtKB/TrEMBL