Dhrs7 (dehydrogenase/reductase 7) - Rat Genome Database

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Gene: Dhrs7 (dehydrogenase/reductase 7) Heterocephalus glaber
Analyze
Symbol: Dhrs7
Name: dehydrogenase/reductase 7
RGD ID: 18900579
Description: ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Experimental Liver Cirrhosis (ortholog); nicotine dependence (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dehydrogenase/reductase SDR family member 7
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473440,993,587 - 41,006,074 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473440,994,786 - 41,006,001 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Dhrs7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473440,993,587 - 41,006,074 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473440,994,786 - 41,006,001 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DHRS7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381460,144,119 - 60,169,889 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1460,144,119 - 60,169,856 (-)EnsemblGRCh38hg38GRCh38
GRCh371460,610,837 - 60,636,607 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361459,681,252 - 59,701,857 (-)NCBINCBI36Build 36hg18NCBI36
Build 341459,681,251 - 59,701,857NCBI
Celera1440,661,330 - 40,682,046 (-)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1440,775,646 - 40,796,362 (-)NCBIHuRef
CHM1_11460,550,762 - 60,571,492 (-)NCBICHM1_1
T2T-CHM13v2.01454,350,401 - 54,376,186 (-)NCBIT2T-CHM13v2.0
Dhrs7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391272,697,127 - 72,711,678 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1272,697,127 - 72,711,683 (-)EnsemblGRCm39 Ensembl
GRCm381272,650,353 - 72,664,828 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1272,650,353 - 72,664,909 (-)EnsemblGRCm38mm10GRCm38
MGSCv371273,751,340 - 73,765,815 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361273,569,194 - 73,583,620 (-)NCBIMGSCv36mm8
Celera1273,765,970 - 73,781,060 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1230.23NCBI
Dhrs7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8697,068,149 - 97,083,744 (-)NCBIGRCr8
mRatBN7.2691,332,259 - 91,347,856 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl691,251,323 - 91,347,892 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx691,702,321 - 91,717,879 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0692,001,790 - 92,017,354 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0691,429,732 - 91,445,294 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0695,522,577 - 95,541,393 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl695,522,577 - 95,541,393 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06104,960,365 - 104,979,222 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4695,049,769 - 95,065,288 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera689,793,235 - 89,808,720 (-)NCBICelera
Cytogenetic Map6q24NCBI
DHRS7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21561,280,412 - 61,301,179 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11460,496,926 - 60,517,636 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01440,750,407 - 40,771,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11459,014,176 - 59,034,877 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1459,014,182 - 59,034,877 (-)Ensemblpanpan1.1panPan2
DHRS7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1835,251,988 - 35,269,880 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl835,251,975 - 35,269,869 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha835,005,894 - 35,023,773 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0835,484,966 - 35,502,849 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl835,484,959 - 35,517,165 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1835,097,280 - 35,115,157 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0835,174,178 - 35,192,051 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0835,534,164 - 35,552,049 (-)NCBIUU_Cfam_GSD_1.0
LOC101966596
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864069,833,360 - 69,850,438 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364954,339,700 - 4,358,547 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364954,341,261 - 4,358,279 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHRS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1189,151,131 - 189,170,534 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11189,153,579 - 189,170,745 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21210,275,976 - 210,293,200 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DHRS7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12437,368,792 - 37,389,433 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2437,368,982 - 37,389,403 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605325,613,416 - 25,634,468 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000020174   ⟹   ENSHGLP00000019974
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473440,993,587 - 41,006,074 (-)Ensembl
RefSeq Acc Id: XM_004837448   ⟹   XP_004837505
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473440,994,786 - 41,006,001 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004837505 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019974
GenBank Protein JAO03083 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004837505   ⟸   XM_004837448
- UniProtKB: A0AAX6NV03 (UniProtKB/TrEMBL),   A0A0P6K8I4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000019974   ⟸   ENSHGLT00000020174


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014306 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020174 ENTREZGENE
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
  SDR_family_member_7 UniProtKB/TrEMBL
NCBI Gene Dhrs7 ENTREZGENE
PANTHER DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7 UniProtKB/TrEMBL
  DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A0P6K8I4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NV03 ENTREZGENE, UniProtKB/TrEMBL