Rdh10 (retinol dehydrogenase 10) - Rat Genome Database

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Gene: Rdh10 (retinol dehydrogenase 10) Heterocephalus glaber
Analyze
Symbol: Rdh10
Name: retinol dehydrogenase 10
RGD ID: 18899934
Description: ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); bud elongation involved in lung branching (ortholog); ear development (ortholog); PARTICIPATES IN retinoic acid metabolic pathway; retinoid cycle metabolic pathway; ASSOCIATED WITH Craniofacial Abnormalities (ortholog); Experimental Liver Cirrhosis (ortholog); Fetal Death (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: retinol dehydrogenase 10 (all-trans)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474417,837,609 - 17,868,431 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474417,838,047 - 17,868,423 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
lipid droplet  (IEA)
membrane  (IEA)
nucleus  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Rdh10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474417,837,609 - 17,868,431 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474417,838,047 - 17,868,423 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RDH10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38873,294,602 - 73,325,281 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl873,294,602 - 73,325,281 (+)EnsemblGRCh38hg38GRCh38
GRCh37874,206,837 - 74,237,516 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36874,369,891 - 74,399,347 (+)NCBINCBI36Build 36hg18NCBI36
Build 34874,369,890 - 74,399,345NCBI
Celera870,204,803 - 70,235,112 (+)NCBICelera
Cytogenetic Map8q21.11NCBI
HuRef869,697,681 - 69,728,383 (+)NCBIHuRef
CHM1_1874,259,535 - 74,290,179 (+)NCBICHM1_1
T2T-CHM13v2.0873,724,122 - 73,754,883 (+)NCBIT2T-CHM13v2.0
Rdh10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,176,106 - 16,202,774 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,175,998 - 16,203,958 (+)EnsemblGRCm39 Ensembl
GRCm38116,105,882 - 16,132,550 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,105,774 - 16,133,734 (+)EnsemblGRCm38mm10GRCm38
MGSCv37116,095,963 - 16,122,631 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36116,091,096 - 16,117,764 (+)NCBIMGSCv36mm8
Celera116,041,876 - 16,068,353 (+)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.94NCBI
Rdh10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr857,969,931 - 7,998,834 (-)NCBIGRCr8
mRatBN7.253,186,671 - 3,215,572 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl53,188,445 - 3,215,572 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx55,305,902 - 5,332,978 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.056,944,767 - 6,971,843 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.056,641,260 - 6,668,810 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.052,605,265 - 2,631,905 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl52,603,505 - 2,632,030 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.052,593,904 - 2,620,243 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.452,286,373 - 2,314,154 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.152,286,372 - 2,314,154 (-)NCBI
Celera52,790,137 - 2,816,729 (-)NCBICelera
Cytogenetic Map5q11NCBI
Rdh10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554446,878,722 - 6,909,421 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554446,878,722 - 6,909,421 (-)NCBIChiLan1.0ChiLan1.0
RDH10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2789,041,778 - 89,072,092 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1864,671,524 - 64,701,024 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0869,833,320 - 69,863,536 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1871,481,094 - 71,510,689 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl871,481,089 - 71,510,689 (+)Ensemblpanpan1.1panPan2
RDH10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12921,886,014 - 21,912,451 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2921,885,012 - 21,911,303 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2922,150,310 - 22,176,734 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02921,995,836 - 22,022,275 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2921,994,920 - 22,022,273 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12922,053,870 - 22,080,295 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02922,090,663 - 22,117,118 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02922,371,574 - 22,398,035 (+)NCBIUU_Cfam_GSD_1.0
Rdh10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530357,360,563 - 57,388,453 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366482,060,125 - 2,088,833 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366482,060,131 - 2,088,021 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RDH10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl462,569,885 - 62,601,439 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1462,569,877 - 62,600,981 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RDH10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1868,903,665 - 68,933,536 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl868,904,352 - 68,933,792 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603972,438,768 - 72,468,649 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000019270   ⟹   ENSHGLP00000019079
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474417,837,609 - 17,868,431 (-)Ensembl
RefSeq Acc Id: XM_004842052   ⟹   XP_004842109
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474417,838,047 - 17,868,423 (-)NCBI
RefSeq Acc Id: XM_021256019   ⟹   XP_021111678
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474417,839,475 - 17,868,423 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004842109 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111678 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04648 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019079
  ENSHGLP00100005168
GenBank Protein JAO02483 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004842109   ⟸   XM_004842052
- Peptide Label: isoform X1
- UniProtKB: G5B5T7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111678   ⟸   XM_021256019
- Peptide Label: isoform X2
- UniProtKB: A0AAX6SSN2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000019079   ⟸   ENSHGLT00000019270


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013673 Ensembl, ENTREZGENE
  ENSHGLG00100003919 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000019270 ENTREZGENE
  ENSHGLT00100005248 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
KEGG Report hgl:101724742 UniProtKB/TrEMBL
NCBI Gene Rdh10 ENTREZGENE
PANTHER PKSB UniProtKB/TrEMBL
  RETINOL DEHYDROGENASE 10 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0AAX6SSN2 ENTREZGENE, UniProtKB/TrEMBL
  G5B5T7 ENTREZGENE, UniProtKB/TrEMBL