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Gene: SIRT7 (sirtuin 7) Chlorocebus sabaeus

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Symbol:

SIRT7

Name:

sirtuin 7

RGD ID:

18782287

Description:

ENCODES a protein that exhibits acyltransferase activity, transferring groups other than amino-acyl groups (inferred); chromatin binding (inferred); histone deacetylase activity, NAD-dependent (inferred); INVOLVED IN protein deacetylation (ortholog); protein deglutarylation (ortholog); protein depropionylation (ortholog); PARTICIPATES IN histone modification pathway; RNA polymerase I transcription pathway; Sirtuin mediated pathway; ASSOCIATED WITH Reperfusion Injury (ortholog); steatotic liver disease (ortholog); systemic scleroderma (ortholog); FOUND IN nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

NAD-dependent protein deacetylase sirtuin-7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SIRT7 (sirtuin 7)	NCBI	Ortholog
Mus musculus (house mouse):	Sirt7 (sirtuin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Sirt7 (sirtuin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sirt7 (sirtuin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SIRT7 (sirtuin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SIRT7 (sirtuin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sirt7 (sirtuin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SIRT7 (sirtuin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sirt7 (sirtuin 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	73,785,223 - 73,792,773 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	73,785,695 - 73,791,947 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	45,237,380 - 45,244,127 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Reperfusion Injury (ISO)

steatotic liver disease (ISO)

systemic scleroderma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IEA)

DNA repair-dependent chromatin remodeling (IEA)

homologous chromosome pairing at meiosis (IEA)

negative regulation of gene expression, epigenetic (IEA)

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA)

negative regulation of protein ubiquitination (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

osteoblast differentiation (IEA)

positive regulation of gluconeogenesis (IEA)

positive regulation of rRNA processing (IEA)

positive regulation of transcription by RNA polymerase I (IEA)

protein deacetylation (ISO)

protein deglutarylation (ISO)

protein depropionylation (ISO)

R-loop processing (IEA)

regulation of DNA repair (IEA)

regulation of mitochondrion organization (IEA)

regulation of protein export from nucleus (IEA)

regulation of transcription by RNA polymerase II (IEA)

regulation of transcription of nucleolar large rRNA by RNA polymerase I (IEA)

rRNA transcription (IEA)

transcription initiation-coupled chromatin remodeling (IEA)

transposable element silencing (IEA)

Cellular Component

chromatin (IEA)

nuclear speck (IEA)

nucleolus (IEA)

nucleolus organizer region (IEA)

nucleoplasm (IEA)

nucleus (IEA,ISO)

site of double-strand break (IEA)

Molecular Function

acyltransferase activity, transferring groups other than amino-acyl groups (IEA)

chromatin binding (IEA)

histone deacetylase activity, NAD-dependent (IEA)

histone H3K18 deacetylase activity, NAD-dependent (IEA)

metal ion binding (IEA)

NAD+ binding (IEA)

NAD-dependent protein lysine deacetylase activity (IEA)

NAD-dependent protein-lysine depropionylase activity (IEA)

protein binding (ISO)

protein methyltransferase activity (IEA)

protein-glutaryllysine deglutarylase activity (IEA)

protein-succinyllysine desuccinylase activity (IEA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

histone modification pathway (ISO)

RNA polymerase I transcription pathway (ISO)

Sirtuin mediated pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

SIRT7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	73,785,223 - 73,792,773 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	73,785,695 - 73,791,947 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	45,237,380 - 45,244,127 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

SIRT7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	81,911,939 - 81,918,176 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	81,911,939 - 81,921,323 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	79,869,815 - 79,876,052 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	77,463,107 - 77,469,332 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	76,473,883 - 76,480,126 (-)	NCBI		Celera
Cytogenetic Map	17	q25.3	NCBI
HuRef	17	75,271,436 - 75,277,679 (-)	NCBI		HuRef
CHM1_1	17	79,956,019 - 79,962,262 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	82,779,099 - 82,785,336 (-)	NCBI		T2T-CHM13v2.0

Sirt7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	120,509,197 - 120,515,840 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	120,509,198 - 120,516,066 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	120,618,371 - 120,625,014 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	120,618,372 - 120,625,240 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	120,479,686 - 120,486,316 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	120,434,461 - 120,441,057 (-)	NCBI		MGSCv36	mm8
Celera	11	132,353,665 - 132,360,296 (-)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	84.34	NCBI

Sirt7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	106,394,802 - 106,401,627 (-)	NCBI		GRCr8
mRatBN7.2	10	105,896,476 - 105,903,301 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	105,896,476 - 105,903,172 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	111,000,317 - 111,006,939 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	110,463,345 - 110,469,976 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	105,816,930 - 105,823,624 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	109,796,046 - 109,802,821 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	109,796,020 - 109,802,739 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	109,389,098 - 109,395,852 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	110,009,669 - 110,016,346 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	110,024,660 - 110,030,830 (-)	NCBI
Celera	10	104,439,874 - 104,446,570 (-)	NCBI		Celera
Cytogenetic Map	10	q32.3	NCBI

Sirt7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955506	1,252,274 - 1,258,728 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955506	1,252,271 - 1,258,728 (+)	NCBI	ChiLan1.0	ChiLan1.0

SIRT7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	98,448,076 - 98,454,320 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	103,348,854 - 103,355,095 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	76,317,560 - 76,323,761 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	82,020,077 - 82,026,016 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	82,020,077 - 82,026,289 (-)	Ensembl	panpan1.1		panPan2

SIRT7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	377,141 - 383,355 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	376,445 - 442,919 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	979,255 - 985,455 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	970,474 - 976,673 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	969,764 - 976,672 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	995,625 - 1,001,822 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	1,122,234 - 1,128,418 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	1,200,924 - 1,207,098 (+)	NCBI		UU_Cfam_GSD_1.0

Sirt7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	987,406 - 993,628 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936594	5,418,796 - 5,424,988 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936594	5,418,331 - 5,425,050 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SIRT7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	1,078,166 - 1,084,119 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	1,078,155 - 1,084,112 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Sirt7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	10,753,333 - 10,764,122 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	10,753,480 - 10,760,601 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SIRT7
124 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008013291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037993127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_501202	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000000219 ⟹ ENSCSAP00000015834

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	16	73,785,695 - 73,791,947 (-)	Ensembl

RefSeq Acc Id:

XM_008013291 ⟹ XP_008011482

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	16	73,785,223 - 73,792,773 (-)	NCBI
Vero_WHO_p1.0	NW_023666077	45,237,380 - 45,244,127 (-)	NCBI

Sequence:

show sequence

CCGTACCTGCTGGGCCAGTCCCACACATTTCCACCCTGCCCCTGGAGCAGCAGCTTTGATACCA
TGGGTGTCCCTTGAGTCTGAGCTAGAGTGTGTCCCCGATAAACTGTGAGACCTCCCTGTTCTTG
GTGACCCCAGTTGGGCTTTGACCCCTCCAGCAACCTTGTGTCCCATCCCTGCCCTTCCTCCCAC
CCCCTCAATCTGCTAGTCCCTGAAGCCTTTAACCAAACGGGAGTGGGCACAGAAAGCCTTCTCC
TGGCAACAGGACAAGGGCTGCCCGCGTGTCCAGCCCTGTTGCTCTCCTGGCACTGAGAGGTGGA
TCCAAGCAGAGTTGATCAGTCCCCCTGCCTGCCCTGCCTAGGTCTAGCCAGGGGAGGTTGTGTG
TGTGTGGGAGAAAACCCCGGGATGTGCTGGGGTGGGATGGAGGTTATTAAAGATCTAAGTGAGG
AGGGGCTGGGGTTTGGATGCGGGGTGAGGCCCGAGCGCTCACACTTCGTGTAGGGCTGGCAGGG
GCCTGACCTCGGGCAGGGCAGTGGCCTTGGTGCCCCACCCCTGCCCTGCGCAGTATTTATTGCT
AAATTATTGTCCAGGAGGGGCAGCACTGGGCCTGGCCCCCCGGGTATTTATTGCTGTACATAGT
GTATGTTTGTGATATATAAGGTTTTCTTTATTTTGTATATGATCAATAAACCTTTTAAAGAGAC
TGGCAGGTGCTTCTTTGGGGCGACGCGGCGGGCGGAGCCGGAAGAGGTGGGTGGGGGCGGGACC
CGTCTTGCGCATGCGCCCTGAGCGCGGCCTGCCGTGTAAGGCGGAAGCGGAAGAGCGGGTCTCC
AGGGGAGCGATGGCAGCCGGGGGTCTGAGCCGCTCGGAACGCAAAGCTGCGGAGCGGGTCCGGA
GGTTGCGGGAGGAGCAGCAGAGGGAGCGCCTCCGCCAGGTGTCGCGCATCCTGAGAAAGGCGGC
GGCGGAGCGCAGCGCCGAGGAGGGCCGGCTGCTGGCCGAGAGCGCGGACCTGGTAACGGAGCTG
CAGGGCCGGAGCCGGCGGCGCGAGGGCCTGAAGCGGCGGCAGGAGGAGGTGTGCGACGACCCGG
AGGAGCTGCGAGGGAAGGTCCGGGAGCTGGCCAGCGCCGTCCGGAACGCCAAATACTTGGTCGT
CTACACAGGCGCGGGAATCAGCACGGCAGCATCTATCCCAGACTACAGGGGCCCTAATGGAGTG
TGGACACTGCTTCAGAAAGGGAGAAGCGTGAGTGCTGCTGACCTGAGTGAGGCCGAGCCAACCC
TCACCCACATGAGCATCACCCGTTTGCATGAGCAGAAGCTGGTGCAGCATGTGGTGTCTCAGAA
CTGTGACGGGCTCCACCTGAGAAGTGGGCTGCCGCGCACGGCCATCTCAGAGCTCCACGGGAAC
ATGTACATTGAAGTCTGCACCTCCTGCGTTCCCAACAGGGAGTACGTGCGAGTGTTTGATGTGA
CGGAACGCACCGCCCTCCACAGACACCAGACAGGCCGGACCTGCCACAAGTGTGGGACCCAGCT
CCGGGACACCATTGTGCACTTTGGAGAGAGGGGGACGTTGGGGCAGCCTCTGAACTGGGAAGCG
GCGACTGAGGCTGCCAGCAGAGCAGACACCATCCTGTGTCTAGGGTCCAGCCTGAAGGTTCTAA
AGAAGTACCCACGCCTCTGGTGCATGACCAAGCCCCCTAGCCGGCGGCCGAAACTCTACATTGT
GAACTTGCAGTGGACCCCGAAGGATGACTGGGCTGCCCTGAAGCTACACGGGAAGTGTGATGAT
GTCATGCGGCTCCTCATGGCGGAGCTGGGCTTGGAGATCCCCGCCTATAGCAGGTGGCAGGATC
CCATTTTCTCACTGGCGACTCCCCTGCGTGCTGGCGAAGAAGGCAGCCACAGTCGGAAGTCGCT
GTGCAGAAGCAGAGAGGAGGCCCCACCTGGGGACCGGGGTGCACCGCTTAGCTCGGCCCCCATC
CTAGGGGGCTGGTTTGGCAGGGGCTGCACAAAACGCACAAAAAGGAAGAAAGTGACGTAACCTG
GTGCTCGATGAAGAACAGTTGGCACTTTGCAGATGGCCAGTGTCACGGTGAAGGCTGGGTTGTC
CCCACGGGTCTAGTGAGAACTCTTTGGGGATGACGTTTTCACCGTGACATTTTTAGCCATTTGT
CCTTGTGGAAGCCCCTTGCACTGCTGCGGTTGTCCCCTGATACGACTTGGCCATGGAGGACACC
TGCCCATCCGGCCTCTATGTCAAGAGGTGGCAGCCACACTTTTCTGTGAGAACGGAACTCGGGT
TATTTCAGCCCCGGCCGGCAGAGTGGAAGCGCCCAGCGGCCTTTCCTCACTCACCAGGCCAGTC
TCAGGGCCTCACCCTATTTCTACTACTTAATGAAAAAGTGTGAAAACTTTATAGAACCCTTTCT
GTACTGGACGTGCGGCAGAGGGGTGGCTCCGAGCCTCGGCTCTATGCAGACCTTTTTATTTCTA
TTAAACGTTTCTGCACTGGT

hide sequence

RefSeq Acc Id:

XM_037993127 ⟹ XP_037849055

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666077	45,238,057 - 45,244,127 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_008011482	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000015834
	ENSCSAP00000015834.1

RefSeq Acc Id:	XP_008011482 ⟸ XM_008013291
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSCSAP00000015834 ⟸ ENSCSAT00000000219

RefSeq Acc Id:	XP_037849055 ⟸ XM_037993127
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000002208	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000000219.1	UniProtKB/TrEMBL
Gene3D-CATH	2.20.28.200	UniProtKB/TrEMBL
	TPP-binding domain	UniProtKB/TrEMBL
InterPro	DHS-like_NAD/FAD-binding_dom	UniProtKB/TrEMBL
	NAD-dep_sirtuin_deacylases	UniProtKB/TrEMBL
	Sirtuin	UniProtKB/TrEMBL
	Ssirtuin_cat_dom	UniProtKB/TrEMBL
NCBI Gene	SIRT7	ENTREZGENE
PANTHER	NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7	UniProtKB/TrEMBL
	NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED	UniProtKB/TrEMBL
Pfam	SIR2	UniProtKB/TrEMBL
PROSITE	SIRTUIN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52467	UniProtKB/TrEMBL
UniProt	A0A0D9S4P5_CHLSB	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - CTD

RGD Manual Annotations