ADAM30 (ADAM metallopeptidase domain 30) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: ADAM30 (ADAM metallopeptidase domain 30) Chlorocebus sabaeus
Analyze
Symbol: ADAM30
Name: ADAM metallopeptidase domain 30
RGD ID: 18776159
Description: ENCODES a protein that exhibits metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN male gonad development (inferred); proteolysis (inferred); ASSOCIATED WITH Hajdu-Cheney syndrome (ortholog); PHGDH deficiency (ortholog); FOUND IN external side of plasma membrane (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: disintegrin and metalloproteinase domain-containing protein 30
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12013,887,509 - 13,890,543 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2013,887,666 - 13,890,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603816,517,240 - 16,520,650 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADAM30
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12013,887,509 - 13,890,543 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2013,887,666 - 13,890,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603816,517,240 - 16,520,650 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ADAM30
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381119,893,533 - 119,896,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1119,893,533 - 119,896,515 (-)EnsemblGRCh38hg38GRCh38
GRCh371120,436,156 - 120,439,138 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361120,237,679 - 120,240,636 (-)NCBINCBI36Build 36hg18NCBI36
Build 341120,148,198 - 120,151,155NCBI
Celera1118,666,878 - 118,669,835 (-)NCBICelera
Cytogenetic Map1p12ENTREZGENE
HuRef1118,294,693 - 118,297,684 (-)NCBIHuRef
CHM1_11120,551,650 - 120,554,641 (-)NCBICHM1_1
T2T-CHM13v2.01119,906,790 - 119,909,772 (-)NCBIT2T-CHM13v2.0
Adam30
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39398,067,950 - 98,071,485 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl398,067,946 - 98,071,485 (+)EnsemblGRCm39 Ensembl
GRCm38398,160,634 - 98,164,169 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl398,160,630 - 98,164,169 (+)EnsemblGRCm38mm10GRCm38
MGSCv37397,964,735 - 97,967,096 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36398,246,217 - 98,248,578 (+)NCBIMGSCv36mm8
Celera399,560,033 - 99,562,394 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map342.63NCBI
Adam30
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82188,440,918 - 188,444,358 (+)NCBIGRCr8
mRatBN7.22185,752,183 - 185,755,623 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2185,752,072 - 185,755,599 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2193,400,568 - 193,404,009 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02191,208,751 - 191,212,192 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02186,033,146 - 186,036,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02200,328,498 - 200,331,938 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2200,328,387 - 200,331,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02219,804,507 - 219,807,947 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42192,997,466 - 193,000,906 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2178,242,634 - 178,246,074 (+)NCBICelera
Cytogenetic Map2q34NCBI
ADAM30
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21112,535,910 - 112,542,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11112,138,361 - 112,144,504 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0182,630,734 - 82,633,448 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11117,628,391 - 117,631,178 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1117,628,573 - 117,631,026 (+)Ensemblpanpan1.1panPan2
LOC100682600
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11756,768,324 - 56,772,594 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1756,399,802 - 56,401,549 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01757,649,632 - 57,651,326 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11756,686,190 - 56,687,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01756,711,459 - 56,713,150 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01757,328,617 - 57,330,326 (-)NCBIUU_Cfam_GSD_1.0
Adam30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050582,557,503 - 2,560,461 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936872578,616 - 580,853 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAM30
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4101,314,710 - 101,316,893 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14101,314,710 - 101,316,974 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24111,215,977 - 111,218,587 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression

RNA-SEQ Expression

hemolymphoid system
mesenchyme
mesoderm
17 17 17

Sequence


Ensembl Acc Id: ENSCSAT00000016793   ⟹   ENSCSAP00000016292
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2013,887,666 - 13,890,095 (+)Ensembl
RefSeq Acc Id: XM_007977331   ⟹   XP_007975522
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12013,887,515 - 13,890,543 (+)NCBI
Vero_WHO_p1.0NW_02366603816,517,240 - 16,520,564 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037997386   ⟹   XP_037853314
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603816,517,240 - 16,520,650 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007975522 (Get FASTA)   NCBI Sequence Viewer  
  XP_037853314 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016292.1
RefSeq Acc Id: XP_007975522   ⟸   XM_007977331
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S603 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000016292   ⟸   ENSCSAT00000016793
RefSeq Acc Id: XP_037853314   ⟸   XM_037997386
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S603 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000001737 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016793.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.390.10 UniProtKB/TrEMBL
  4.10.70.10 UniProtKB/TrEMBL
InterPro ADAM_Cys-rich UniProtKB/TrEMBL
  Disintegrin_dom UniProtKB/TrEMBL
  Disintegrin_dom_sf UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  Reprolysin_adamalysin UniProtKB/TrEMBL
NCBI Gene ADAM30 ENTREZGENE
PANTHER ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN UniProtKB/TrEMBL
  DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 30 UniProtKB/TrEMBL
Pfam ADAM_CR UniProtKB/TrEMBL
  Disintegrin UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
PRINTS DISINTEGRIN UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  DISINTEGRIN_2 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  DISIN UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF57552 UniProtKB/TrEMBL
UniProt A0A0D9S603 ENTREZGENE, UniProtKB/TrEMBL