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Gene: SPEN (spen family transcriptional repressor) Chlorocebus sabaeus
Symbol: SPEN
Name: spen family transcriptional repressor
RGD ID: 18767499
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); RNA polymerase II transcription factor binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription, DNA-templated (ortholog); positive regulation of neurogenesis (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); Prostatic Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); transcription repressor complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: msx2-interacting protein
Homo sapiens (human) : SPEN (spen family transcriptional repressor)  HGNC  Alliance
Mus musculus (house mouse) : Spen (spen family transcription repressor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Spen (spen family transcriptional repressor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spen (spen family transcriptional repressor)
Pan paniscus (bonobo/pygmy chimpanzee) : SPEN (spen family transcriptional repressor)
Canis lupus familiaris (dog) : SPEN (spen family transcriptional repressor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spen (spen family transcriptional repressor)
Sus scrofa (pig) : SPEN (spen family transcriptional repressor)
Heterocephalus glaber (naked mole-rat) : Spen (spen family transcriptional repressor)
more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1 Ensembl20116,361,008 - 116,458,064 (-)Ensembl
ChlSab1.120116,359,981 - 116,458,156 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on SPEN
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 18767499
Created: 2020-01-22
Species: Chlorocebus sabaeus
Last Modified: 2020-01-22
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.