ADH6 (alcohol dehydrogenase 6 (class V)) - Rat Genome Database

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Gene: ADH6 (alcohol dehydrogenase 6 (class V)) Chlorocebus sabaeus
Analyze
Symbol: ADH6
Name: alcohol dehydrogenase 6 (class V)
RGD ID: 18742770
Description: ENCODES a protein that exhibits alcohol dehydrogenase (NAD+) activity (inferred); all-trans-retinol dehydrogenase (NAD+) activity (inferred); metal ion binding (inferred); INVOLVED IN retinoic acid metabolic process (inferred); retinol metabolic process (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alcohol dehydrogenase 6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1747,294,074 - 47,309,771 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl747,291,221 - 47,309,102 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603725,726,580 - 25,741,357 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADH6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1747,294,074 - 47,309,771 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl747,291,221 - 47,309,102 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603725,726,580 - 25,741,357 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ADH6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38499,202,639 - 99,219,246 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl499,202,638 - 99,219,537 (-)EnsemblGRCh38hg38GRCh38
GRCh374100,123,796 - 100,140,403 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364100,342,818 - 100,359,426 (-)NCBINCBI36Build 36hg18NCBI36
Build 344100,483,056 - 100,497,579NCBI
Celera497,421,068 - 97,437,673 (-)NCBICelera
Cytogenetic Map4q23NCBI
HuRef495,861,628 - 95,878,222 (-)NCBIHuRef
CHM1_14100,100,226 - 100,116,832 (-)NCBICHM1_1
T2T-CHM13v2.04102,517,454 - 102,534,061 (-)NCBIT2T-CHM13v2.0
Adh6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393138,047,176 - 138,064,621 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3138,047,536 - 138,064,622 (+)EnsemblGRCm39 Ensembl
GRCm383138,341,412 - 138,358,859 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,341,775 - 138,358,861 (+)EnsemblGRCm38mm10GRCm38
MGSCv373138,007,024 - 138,058,017 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,280,246 - 138,296,247 (+)NCBIMGSCv36mm8
Celera3144,748,453 - 144,766,508 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map364.21NCBI
Adh6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,576,612 - 229,608,359 (+)NCBIGRCr8
mRatBN7.22226,903,208 - 226,934,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,903,250 - 226,934,534 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2234,650,831 - 234,713,541 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,550,567 - 232,613,268 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02227,415,250 - 227,477,952 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,656,568 - 243,687,857 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,550,627 - 243,687,857 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02262,193,252 - 262,224,625 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,907,340 - 235,938,846 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12235,894,079 - 235,925,586 (+)NCBI
Celera2219,059,887 - 219,091,198 (+)NCBICelera
Cytogenetic Map2q44NCBI
ADH6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,265,685 - 97,275,876 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1497,544,454 - 97,560,241 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0491,604,422 - 91,621,342 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,266,052 - 102,283,210 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,264,224 - 102,283,210 (-)Ensemblpanpan1.1panPan2
LOC100856515
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13221,383,276 - 21,397,237 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3220,533,206 - 20,547,149 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03221,569,512 - 21,583,534 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13221,547,156 - 21,561,148 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03221,361,716 - 21,375,665 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03218,519,779 - 18,533,782 (+)NCBIUU_Cfam_GSD_1.0
LOC110261964
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.18121,170,548 - 121,181,415 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in ADH6
258 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000002144   ⟹   ENSCSAP00000000470
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl747,291,221 - 47,309,102 (-)Ensembl
RefSeq Acc Id: XM_037988719   ⟹   XP_037844647
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603725,726,580 - 25,741,357 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037844647 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000470.1
Ensembl Acc Id: ENSCSAP00000000470   ⟸   ENSCSAT00000002144
RefSeq Acc Id: XP_037844647   ⟸   XM_037988719
- UniProtKB: A0A0D9QVT1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004112 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002144.1 UniProtKB/TrEMBL
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro ADH_C UniProtKB/TrEMBL
  ADH_N UniProtKB/TrEMBL
  ADH_Zn_CS UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103236016 UniProtKB/TrEMBL
NCBI Gene ADH6 ENTREZGENE
PANTHER ALCOHOL DEHYDROGENASE UniProtKB/TrEMBL
  PTHR43880:SF20 UniProtKB/TrEMBL
Pfam ADH_N UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/TrEMBL
PROSITE ADH_ZINC UniProtKB/TrEMBL
Superfamily-SCOP SSF50129 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt A0A0D9QVT1 ENTREZGENE, UniProtKB/TrEMBL