GPX5 (glutathione peroxidase 5) - Rat Genome Database

Name: GPX5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: GPX5 (glutathione peroxidase 5) Chlorocebus sabaeus

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Symbol:

GPX5

Name:

glutathione peroxidase 5

RGD ID:

18719610

Description:

ENCODES a protein that exhibits glutathione peroxidase activity (inferred); peroxidase activity (inferred); INVOLVED IN cellular response to oxidative stress (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); megacolon (ortholog); FOUND IN extracellular space (ortholog); sperm plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

epididymal secretory glutathione peroxidase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPX5 (glutathione peroxidase 5)	NCBI	Ortholog
Mus musculus (house mouse):	Gpx5 (glutathione peroxidase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Gpx5 (glutathione peroxidase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPX5 (glutathione peroxidase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPX5 (glutathione peroxidase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpx5 (glutathione peroxidase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPX5 (glutathione peroxidase 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	44,027,538 - 44,037,304 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	44,028,543 - 44,036,686 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	28,225,741 - 28,234,766 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

megacolon (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular oxidant detoxification (IEA)

cellular response to oxidative stress (ISO)

response to oxidative stress (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (ISO)

sperm plasma membrane (ISO)

Molecular Function

glutathione peroxidase activity (IEA)

peroxidase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GPX5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	44,027,538 - 44,037,304 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	44,028,543 - 44,036,686 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	28,225,741 - 28,234,766 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

GPX5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	28,525,881 - 28,534,955 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	28,525,881 - 28,534,955 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	28,493,658 - 28,502,732 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	28,601,768 - 28,609,923 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	28,601,767 - 28,609,923	NCBI
Celera	6	30,100,218 - 30,109,121 (+)	NCBI		Celera
Cytogenetic Map	6	p22.1	NCBI
HuRef	6	28,300,120 - 28,309,014 (+)	NCBI		HuRef
CHM1_1	6	28,496,188 - 28,505,099 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	28,397,310 - 28,406,348 (+)	NCBI		T2T-CHM13v2.0

Gpx5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	21,470,599 - 21,476,897 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	21,470,599 - 21,476,901 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	21,286,429 - 21,292,727 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	21,286,429 - 21,292,731 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	21,378,298 - 21,384,555 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	21,293,898 - 21,300,151 (-)	NCBI		MGSCv36	mm8
Celera	13	21,553,579 - 21,559,835 (-)	NCBI		Celera
Cytogenetic Map	13	A3.1	NCBI
cM Map	13	7.73	NCBI

Gpx5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	48,131,853 - 48,138,801 (+)	NCBI		GRCr8
mRatBN7.2	17	43,436,126 - 43,443,074 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	43,416,340 - 43,443,074 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	45,493,484 - 45,500,432 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	50,252,586 - 50,259,534 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	44,743,174 - 44,750,131 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	45,508,657 - 45,518,686 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	45,467,015 - 45,518,686 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	57,952,807 - 57,962,120 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.1	17	51,091,844 - 51,098,176 (+)	NCBI
Celera	17	53,035,706 - 53,042,631 (-)	NCBI		Celera
Cytogenetic Map	17	q11	NCBI

GPX5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	43,153,860 - 43,162,096 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	39,154,800 - 39,163,014 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	28,340,291 - 28,348,504 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	29,010,528 - 29,018,737 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	29,010,528 - 29,018,737 (+)	Ensembl	panpan1.1		panPan2

GPX5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	25,653,627 - 25,662,490 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	25,653,615 - 25,662,490 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	25,512,937 - 25,521,120 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	25,952,095 - 25,960,969 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	25,952,083 - 25,960,969 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	25,615,767 - 25,624,631 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	25,671,318 - 25,679,525 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	27,140,044 - 27,148,915 (+)	NCBI		UU_Cfam_GSD_1.0

Gpx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	28,952,020 - 28,961,691 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936914	487,163 - 496,465 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPX5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	22,291,986 - 22,300,727 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	22,289,432 - 22,300,727 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	24,233,520 - 24,244,829 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

hemolymphoid system	mesenchyme	mesoderm
18	18	18

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007973342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038005681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000006100 ⟹ ENSCSAP00000004311

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	17	44,028,543 - 44,036,686 (-)	Ensembl

RefSeq Acc Id:

XM_007973342 ⟹ XP_007971533

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	17	44,027,538 - 44,037,304 (-)	NCBI
Vero_WHO_p1.0	NW_023666044	28,225,741 - 28,234,766 (+)	NCBI

Sequence:

show sequence

ATTTGATTTTCTATCTCATGCCCATTTTTTTCTGTTGGTCTAGTAGTTTTTTCTTACTGCTATA
TAAGCACTTGAAATCATTTCCAAGCATTTGTATTAATTTGCTGTCCTTCACATACATTGTGACT
ATTTCCCCTCCTGGGGCCAGTTTCCTCCTAACTCTTTTTGAGAGATACTAGATGGCCTGCCCAT
CCTTTGATTTTTTTCAAGCTCAAATAATATAAGAAATAACATTTGAAATGTCTAGACCAACCCT
TTTGCAGTGACTTTACTGGGAGGTTGCATCAGCATCTAGACACTTCCATACATTGAGGAAAAAC
AGACACCAGTCTTTAAGGACCTCAGAGGGCTTGCCATCACCCATTTATAATTTTCCCAGAACTT
GTGAGTCCCAGGTCCTCATTGCACTGGTGAGCGCTGAGTGCTCACGGGGGTGTGTGTGGGACAG
GATGTGGTTTGAGTTCTGTGATCCTCACCCCGACCTCATGCGTCCAGAATCCTTGCAGCCCTGT
GATTGGCCTGTGGGGGCTTGGGCTAAGTCCCTGCCAAGATACCAAAAGACTGCGGAGGTGGGCA
AGGACCTCAGGCCCCCAGACTAGCAATCTACAAACACTAGTCATGACTAGACAGTTAAGGGTCG
TCCATCTGCTTCCCCTTCTCCTAGCCTGCTTTGTGCAAACAAGTCCCAAGCAGGAGACGATGAA
GATGGATTGTCACAAAGATGAGAAAGGCACCATCTATGACTATGAGGCCATCGCACTTAATAAG
AACGAATATGTTCCCTTCAAGCAGTATGTGGGCAAGCACATCCTCTTCGTCAACGTGGCCACCT
ACTGTGGTCTGACAGCGCAATATCCTGAACTAAATGCACTCCAGGAGGAGCTGAAGCCCTATGG
TCTAGTCGTGCTGGGCTTTCCCTGCAACCAATTTGGAAAGCAAGAACCAGGAGATAACAAAGAG
ATTCTTCCTGGGCTCAAGTATGTCCGTCCAGGGGGAGGATTTGTACCTAATTTCCAGCTTTTTG
AGAAAGGGGATGTGAATGGTGAAAAAGAACAGAAAGTCTTCAGCTTCTTGAAGCACTCCTGTCC
TCATCCCTCTGAGATTTTGGGCACATTCAAATCTATATCCTGGAACCCTGTAAAGGTCCATGAC
ATCCGCTGGAACTTTGAAAAGTTCCTGGTGGGGCCTGATGGAATCCCTGTCATGCGCTGGTCCC
ACCAGGCTACCGTCAGCTCAGTAAAGACAGACATCCTGGCGTACTTGAAGCAATTCAAAACCAA
ATAGGAAGGTGGAGTTAAGGGCAGGAGCAATCCTACTTCTACTTCTCACCTAATGACTTGCTCC
CCCTCTCCCCCCAAAAAAGGAATATCCATCTTCTCACCACACTCTCTTCCTGCATGGGCTCCAA
CTGAGCAAATCACCTCCACATACTGCCAGAATTCCCACTCTCCACAAACTAGATTTATATTTGG
AAGGATACTGCTCTTTTGCCTCTCAAGAGTATGTGGGTGAAGACTGAAAAAAATGGAAACCTAA
AATCCCCAGACCTCTGTTACAGGTTGAATCATTCGTATCCACCAGAGGGAAATCATCCTTCCAC
GACAATGGTTCATCGGCCATCACATCCTGAAGAAGAACATTCCTAGACATTCTGATGCTTCCAT
CTATCTCCACCCTAGAGGTGTAGAAATAGCAATGGGGTCATAGTCACACAGTTTAGGTTCCACT
TCATAACATTTTTTGTCTCCTAGGACAAACATGTATCATCAGTTTCCAACTGTTTTGGCTCAGT
TTTCATCCATGACACCTCCCCCCACCAGTCATTCTCCTGTGGGAGCAAGAACATTGCTTCACAA
GAAGAGAGGGCATCTCCATGCTGGTGGGACCCAGAACCTGTCTCTGTTCGGCCCTAAAAAAGTT
TTCCTTATTGTCTGATCTTTAATGCATTCAGGTTACGGCACCTGGACAGAAATGCCCTTTATCT
TTTGAAGGATGGGATTTCCCATCTCAACCCTGGATTCCTCAGCTTCAGAATGAGCCCTGCCACT
GTCTCCAATAAAATGTTTTCTGCAGCATCGACGATCTCTATGGTGGTTTTAAAATCCCGTCTGG
TCCTTGAACTCATTTTATCTCCCTCCTCTTTCTTACTCTGTCACAAATGATGTATTGCCCACAT
GACCTGAGCCCCCCCAGACAGAAAGATTTACATTTGGAAGAGTGTCACCCGATACCTCTCAGTT
GTCATTCCTCTTCAGAAATTGCCTCAACCTAAGTCTGTCCCCTTTC

hide sequence

RefSeq Acc Id:

XM_038005681 ⟹ XP_037861609

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666044	28,225,741 - 28,233,851 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_007971533	(Get FASTA)	NCBI Sequence Viewer
	XP_037861609	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000004311.1

RefSeq Acc Id:	XP_007971533 ⟸ XM_007973342
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R6S2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000004311 ⟸ ENSCSAT00000006100

RefSeq Acc Id:	XP_037861609 ⟸ XM_038005681
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000008050	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000006100.1	UniProtKB/TrEMBL
Gene3D-CATH	Glutaredoxin	UniProtKB/TrEMBL
InterPro	Glutathione_peroxidase	UniProtKB/TrEMBL
	GPX_AS	UniProtKB/TrEMBL
	GPX_CS	UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/TrEMBL
KEGG Report	csab:103221912	UniProtKB/TrEMBL
NCBI Gene	GPX5	ENTREZGENE
PANTHER	EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE	UniProtKB/TrEMBL
	PTHR11592	UniProtKB/TrEMBL
Pfam	GSHPx	UniProtKB/TrEMBL
PIRSF	Glutathion_perox	UniProtKB/TrEMBL
PRINTS	GLUTPROXDASE	UniProtKB/TrEMBL
PROSITE	GLUTATHIONE_PEROXID_1	UniProtKB/TrEMBL
	GLUTATHIONE_PEROXID_2	UniProtKB/TrEMBL
	GLUTATHIONE_PEROXID_3	UniProtKB/TrEMBL
	PROKAR_LIPOPROTEIN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52833	UniProtKB/TrEMBL
UniProt	A0A0D9R6S2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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