PRSS57 (serine protease 57) - Rat Genome Database

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Gene: PRSS57 (serine protease 57) Chlorocebus sabaeus
Analyze
Symbol: PRSS57
Name: serine protease 57
RGD ID: 18709064
Description: ENCODES a protein that exhibits heparin binding (ortholog); serine-type peptidase activity (ortholog); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH cerebral creatine deficiency syndrome (ortholog); COVID-19 (ortholog); cyclic hematopoiesis (ortholog); FOUND IN azurophil granule lumen (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protease, serine 57
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16443,859 - 449,539 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6444,098 - 449,152 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660818,505,941 - 8,511,532 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PRSS57
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16443,859 - 449,539 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6444,098 - 449,152 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660818,505,941 - 8,511,532 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PRSS57
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819685,546 - 695,452 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19685,546 - 695,498 (-)EnsemblGRCh38hg38GRCh38
GRCh3719685,546 - 695,452 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3619636,546 - 646,461 (-)NCBINCBI36Build 36hg18NCBI36
Build 3419636,545 - 646,461NCBI
Celera19120,996 - 132,062 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19455,352 - 465,453 (-)NCBIHuRef
CHM1_119685,251 - 695,165 (-)NCBICHM1_1
T2T-CHM13v2.019639,634 - 649,468 (-)NCBIT2T-CHM13v2.0
Prss57
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,617,308 - 79,630,523 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,617,308 - 79,626,795 (-)EnsemblGRCm39 Ensembl
GRCm381079,781,474 - 79,794,684 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,781,474 - 79,790,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv371079,244,219 - 79,251,730 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,244,219 - 79,251,730 (-)NCBIMGSCv36mm8
Celera1080,796,169 - 80,803,685 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Prss57
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,563,477 - 10,573,617 (+)NCBIGRCr8
mRatBN7.279,915,667 - 9,922,996 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,917,484 - 9,922,922 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,798,509 - 12,803,869 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,676,590 - 14,681,950 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,535,791 - 12,541,268 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,798,310 - 12,804,668 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,798,868 - 12,804,283 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,968,017 - 12,975,388 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,431,197 - 11,436,541 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,431,196 - 11,436,541 (+)NCBI
Celera78,091,033 - 8,096,377 (+)NCBICelera
Cytogenetic Map7q11NCBI
Prss57
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554957,067,844 - 7,077,048 (+)NCBIChiLan1.0ChiLan1.0
PRSS57
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,009,782 - 5,027,487 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,246,843 - 4,265,570 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v019440,415 - 452,535 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.119650,617 - 652,304 (-)NCBIpanpan1.1PanPan1.1panPan2
PRSS57
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,873,891 - 57,877,890 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,874,770 - 57,877,888 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,676,792 - 57,680,073 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,617,342 - 58,620,632 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,617,180 - 58,620,630 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,671,521 - 57,674,808 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02058,151,008 - 58,154,302 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,354,352 - 58,357,640 (+)NCBIUU_Cfam_GSD_1.0
PRSS57
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,650,879 - 77,655,712 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,649,741 - 77,657,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2278,325,996 - 78,327,174 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in PRSS57
205 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
30 22 20 27 27 23 15

Sequence


Ensembl Acc Id: ENSCSAT00000010866   ⟹   ENSCSAP00000008951
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl6444,098 - 449,152 (-)Ensembl
RefSeq Acc Id: XM_007994549   ⟹   XP_007992740
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.16443,859 - 449,539 (-)NCBI
Vero_WHO_p1.0NW_0236660818,505,941 - 8,511,532 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007994550   ⟹   XP_007992741
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.16443,859 - 449,536 (-)NCBI
Vero_WHO_p1.0NW_0236660818,505,942 - 8,511,532 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007992740 (Get FASTA)   NCBI Sequence Viewer  
  XP_007992741 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008951.1
RefSeq Acc Id: XP_007992740   ⟸   XM_007994549
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RK12 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007992741   ⟸   XM_007994550
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RK12 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000008951   ⟸   ENSCSAT00000010866


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012771 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010866.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
KEGG Report csab:103233579 UniProtKB/TrEMBL
NCBI Gene PRSS57 ENTREZGENE
PANTHER KALLIKREIN-RELATED UniProtKB/TrEMBL
  SERINE PROTEASE 57 UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A0D9RK12 ENTREZGENE, UniProtKB/TrEMBL