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Gene: IQGAP2 (IQ motif containing GTPase activating protein 2) Chlorocebus sabaeus

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Symbol:

IQGAP2

Name:

IQ motif containing GTPase activating protein 2

RGD ID:

18692282

Description:

ENCODES a protein that exhibits actin filament binding (inferred); Arp2/3 complex binding (inferred); calmodulin binding (inferred); INVOLVED IN Arp2/3 complex-mediated actin nucleation (inferred); mitotic actomyosin contractile ring assembly actin filament organization (inferred); regulation of actin cytoskeleton organization (inferred); ASSOCIATED WITH Brain Neoplasms (ortholog); hepatocellular carcinoma (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN microtubule (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ras GTPase-activating-like protein IQGAP2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	70,672,171 - 70,979,766 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	70,672,553 - 70,979,763 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	19,502,207 - 19,811,126 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain Neoplasms (ISO)

hepatocellular carcinoma (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Arp2/3 complex-mediated actin nucleation (IEA)

mitotic actomyosin contractile ring assembly actin filament organization (IEA)

regulation of actin cytoskeleton organization (IEA)

thrombin-activated receptor signaling pathway (IEA)

Cellular Component

cell cortex (IEA)

cell surface (IEA)

cytoplasm (IEA)

filopodium (IEA)

lamellipodium (IEA)

microtubule (ISO)

microvillus (IEA)

Molecular Function

actin filament binding (IEA)

Arp2/3 complex binding (IEA)

calmodulin binding (IEA)

GTPase activator activity (IEA)

phosphatidylinositol-3,4,5-trisphosphate binding (IEA)

small GTPase binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

IQGAP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	70,672,171 - 70,979,766 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	70,672,553 - 70,979,763 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	19,502,207 - 19,811,126 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

IQGAP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	76,403,285 - 76,708,132 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	76,403,285 - 76,708,132 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	75,699,110 - 76,003,957 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	75,734,905 - 76,039,713 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	75,734,904 - 76,039,711	NCBI
Celera	5	71,592,826 - 71,897,903 (+)	NCBI		Celera
Cytogenetic Map	5	q13.3	NCBI
HuRef	5	70,906,692 - 71,211,466 (+)	NCBI		HuRef
CHM1_1	5	75,131,847 - 75,437,149 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	76,885,042 - 77,189,993 (+)	NCBI		T2T-CHM13v2.0

Iqgap2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	95,763,685 - 96,028,788 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	95,763,682 - 96,028,991 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	95,627,177 - 95,892,280 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	95,627,174 - 95,892,483 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	96,397,132 - 96,661,877 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	96,397,132 - 96,661,877 (-)	NCBI		MGSCv36	mm8
Celera	13	99,243,963 - 99,510,431 (-)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI
cM Map	13	50.26	NCBI

Iqgap2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	28,629,558 - 28,904,649 (-)	NCBI		GRCr8
mRatBN7.2	2	26,894,836 - 27,170,270 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	26,894,825 - 27,170,279 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	26,161,628 - 26,439,067 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	26,167,199 - 26,438,790 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	45,295,534 - 45,569,560 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	26,039,689 - 26,147,538 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	22,958,327 - 23,102,329 (-)	NCBI		Celera
Cytogenetic Map	2	q12	NCBI

Iqgap2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	24,167,104 - 24,385,146 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	24,167,985 - 24,384,912 (-)	NCBI	ChiLan1.0	ChiLan1.0

IQGAP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	38,597,137 - 38,902,374 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	36,750,767 - 37,056,000 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	38,593,574 - 38,900,327 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	39,137,539 - 39,516,894 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	39,138,359 - 39,516,596 (-)	Ensembl	panpan1.1		panPan2

IQGAP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	29,894,192 - 30,134,594 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	29,894,870 - 30,174,259 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	31,132,907 - 31,420,147 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	29,818,056 - 30,105,892 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	29,818,467 - 30,106,093 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	29,749,579 - 30,036,702 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	29,730,444 - 30,016,347 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	30,099,810 - 30,387,253 (-)	NCBI		UU_Cfam_GSD_1.0

Iqgap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	190,317,091 - 190,603,571 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936549	255,303 - 541,917 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936549	256,097 - 541,860 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IQGAP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	85,294,530 - 85,633,642 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	85,294,423 - 85,633,645 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	86,916,946 - 87,086,957 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Iqgap2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624869	889,091 - 1,171,983 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624869	888,868 - 1,172,747 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in IQGAP2
7828 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007975849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007975858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007975863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007975872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_073014668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_073014669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_073014670	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_073014671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000013459 ⟹ ENSCSAP00000011459

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	4	70,672,553 - 70,979,763 (+)	Ensembl

RefSeq Acc Id:

XM_007975849 ⟹ XP_007974040

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	4	70,672,171 - 70,979,766 (+)	NCBI
Vero_WHO_p1.0	NW_023666049	19,502,207 - 19,811,126 (+)	NCBI

Sequence:

show sequence

TCGGCCCCTTCCCTCTCCCCCGAGGGAGAAGGGGCGGGTCCACGCGGCCTGGGCGCTGCGGCCA
GCACGCGGTAGGGGTCGCTGCGTCTCGGCGCGCGCTCCCACCGCGGAGAATAACGGGGCCTGGC
TGGAGGAGAAAGGAAACCTGCTGCGGGAGGCGGCGGCGGCCGGCCAGGGAGCGAAGGAGGAGAG
TTCACTTTTACTCCAGTGTCAGCGCGCTGCGGCCGCGGCTGGCGCTGGGGAGAGAGCACCGAGG
GAGCGGGTCGCAGATCTTCGGGCGGCCCCGGGAAATCGGCAAGAGGCGGGATCCGAGCGCGCCG
GCGGGGCGCAGAGCCCGCGAGCCTGGCCAGCGAGGGGAGCCGCGGGGGGCGCGCCCCGGGCGGG
CCCCCGGAGCCGCGCAGGATGCCCCGCGAAGAGCTGCCGTCGCTGCAGAGACCCCGCTATGGCT
CTATTGTGGACGATGAAAGGCTCTCTGCAGAGGAGATGGATGAGAGGAGGCGGCAGAACATTGC
TTATGAATATCTGTGCCACTTAGAGGAAGCCAAAAGGTGGATGGAAGTTTGCTTAGTTGAAGAA
TTGCCACCAACCACTGAACTGGAAGAAGGGCTCCGGAATGGAGTTTACCTTGCAAAGTTAGCCA
AGTTCTTTGCCCCGAAAATGGTATCAGAGAAAAAGATCTATGATGTGGAACAAACACGTTATAA
GAAGTCCGGCCTTCATTTTCGACACACAGATAATACTGTCCAGTGGTTAAGAGCGATGGAGTCT
ATTGGTCTCCCCAAGATATTTTATCCAGAAACAACAGATGTCTATGATCGGAAAAACATACCAA
GAATGATATATTGCATTCATGCACTGAGTTTATATCTGTTCAAACTAGGAATAGCACCCCAGAT
CCAGGATTTGTTGGGCAAAGTAGACTTCACAGAGGAGGAAATCAGTAATATGAGAAAAGAACTT
GAGAAATACGGAATACAGATGCCGTCTTTCAGCAAAATAGGTGGTATTCTGGCCAATGAACTGT
CCGTGGATGAAGCTGCATTACATGCTGCAGTTATAGCCATTAATGAAGCAGTTGAAAAAGGAGT
AGCAGAGCAGACCATTGTAACACTAAGAAACCCAAATGCAGTTTTAACTTTAGTGGATGACAAC
CTTGCACCAGAATATCAGAAAGAGCTCTGGGATGCCAAAAAGAAAAAAGAGGAAAATGCAAGAC
TGAAGAATAGCTGTATTTCAGAAGAAGAAAGAGATGCTTATGAAGAACTGCTGACGCAAGCAGA
AATCCAAGGCAATATTAATAAAGTCAACAGGCAGGCTGCGGTGGACCATATTAATGCTGTCATT
CCGGAAGGTGACCCCGAGAATACACTGCTTGCACTGAAGAAACCAGAAGCCCAGCTGCCTGCTG
TTTATCCCTTTGCTGCTGCCATGTATCAGAACGAACTTTTCAACCTCCAGAAACAGAACGCCAT
GAACTACTTGGCCCATGAGGAGCTTTTGATTGCTGTGGAAATGTTGTCTGCTGTTGCTTTACTA
AACCAGGCCTTGGAAAGCAACGATCTTGTGTCTGTGCAGAATCAACTCAGAAGCCCCACAATAG
GCTTAAACAATCTGGACAAGGCATATGTGGAACGTTATGCAAACACACTACTCTCTGTTAAACT
AGAAGTTTTATCCCAAGGACAAGATAACTTAAGCTGGAATGAAATTCAGAATTGTATTGATATG
GTTAATGCTCAAATTCAAGAAGAAAATGACCGAATTGTAGCTGTAGGGTACATCAATGAAGCTA
TTGATGAAGGGAATCCTTTGAGGACTTTAGAAACTTTGCTCCTACCTACTGCGAATATTAGTGA
TGTGGACCCAGCCCATGCCCAGCACTACCAGGATGTTTTATACCATGCTAAATCACAGAAACTC
GGAGACTCTGAGAGTGTTTCCAAATTGCTTTGGCTGGATGAGATACAGCAAGCCATCGACGAGG
CCAATGTGGACGAGGACAGAGCAAAACAATGGGTTACTCTGGTGGTTGATGTTAATCAGTGTTT
GGAAGGAAAAAAATCAAGTGATATTTTGTCTGTATTGAAGTCTTCCACTTCTAATGCAAATGAC
ATAATCCCGGAGTGTGCTGACAAATACCATGATGCCCTTGTGAAGGCGAAAGAGCTCAAATCTG
AAAGAGTGTCTAGTGAAGGTTCATGGCTCAAACTCAACCTGAATGAAAAATATGACTACTGTTA
CAACATTGATTCAAAAGAGGGTTCCTGGGTCATACCTGAATCATGCTTGTATAAAGAATCATGG
CTCACAGGAAAAGAAATCGAGGACATAATTGAGGAAGTCACAGTAGGTTACATTCGTGAGAATA
TATGGTCTGCTTCAGAAGAGATGCTTCTTCGCTTTCAAGCCACAAGTTCAGGACCCATCCTTAG
GGAAGAGTTTGAAGCTAGAAAATCATTTTTGCATGAACAAGAAGAGAATGTGGTCAAAATACAG
GCTTTTTGGAAAGGATGTAAACAACAGAAGGTGTATATGCACAGGCGGCAAACATTCATTGATA
ATACTGATTCTATTGTGAAGATTCAGTCCTGGTTCCGAATGGCAACTGCAAGAAAGAGCTATCT
TTCAAGACTACAGTATTTCAGAGATCATAATAATGAAATTGTGAAAATACAGTCACTGCTGAGA
GCGAACAAAGCTAGAGATGACTACAAAACACTGGTTGGCTCTGAAAATCCACCATTAACAGTAA
TTCGCAAATTTGTATACCTGTTGGACCAAAGTGATTTGGATTTCCAGGAGGAACTAGAGGTTGC
ACGATTAAGGGAAGAAGTAGTGACCAAGATCAGGGCCAATCAACAGCTGGAAAAAGACCTGAAC
CTGATGGACATCAAGATTGGACTCCTGGTGAAGAACAGGATCACACTAGAGGATGTAATTTCAC
ACAGTAAAAAGCTGAATAAGAAAAAAGGAGGAGAAATGGAAATACTGAATAACACCGACAACCA
AGGAATAAAAAGTTTGAGTAAGGAGAGGAGAAAAACACTAGAAACATATCAGCAACTGTTTTAC
CTTTTACAGACCAACCCTTTATACTTGGCTAAGCTGATTTTCCAGATGCCACAGAACAAGTCCA
CTAAATTTATGGATACTGTTATTTTCACACTATATAATTATGCCTCTAATCAGCGAGAAGAATA
TCTACTTCTCAAACTTTTTAAAACTGCTCTGGAGGAAGAAATAAAATCGAAGGTGGACCAGGTA
CAGGACATAGTTACTGGTAACCCTACAGTCATCAAGATGGTCGTCAGCTTCAATAGAGGTGCCC
GGGGACAGAACACCCTGCGCCAACTCCTGGCTGCAGTGGTGAAAGAGATCATCGAGGACAAGTC
GCTGATTATCAACACTAACCCTGTAGAGGTGTACAAGGCTTGGGTGAACCAACTAGAAACACAG
ACTGGAGAGGCCAGCAAGTTGCCTTATGATGTGACCACAGAACAAGCTCTAACATACCCAGAAG
TGAAAAATAAACTAGAGGCTTCCATTGAGAACCTGAGAAGGGTCACCGACAAAGTCCTGAATTC
TATCATTTCTTCCCTTGATCTACTGCCTTATGGATTGAGGTATATAGCCAAAGTACTGAAGAAT
TCGATCCATGAGAAATTCCCCGATGCAACAGAAGATGAGCTATTAAAGATTGTTGGAAACCTCC
TGTACTATCGGTACATGAATCCAGCCATTGTAGCTCCAGATGGCTTTGATATCATCGACATGAC
AGCTGGAGGTCAGATAAATTCTGACCAAAGGAGAAACTTAGGATCGGTGGCCAAGGTTCTTCAG
CACGCAGCCTCCAACAAGCTGTTTGAAGGAGAAAATGAGCATCTCTCATCTATGAACAATTATT
TATCAGAGACGTATCAGGAATTCAGGAAATATTTCAAAGAAGCATGTAATGTCCCTGAGCCAGA
AGAGAAGTTTAATATGGACAAATACACAGACCTGGTGACAGTCAGCAAACCAGTCATTTATATT
TCAATAGAAGAAATCATCAGCACACATTCACTCCTGTTGGAACACCAGGATGCAATTGCCCCTG
AAAAAAATGACTTACTGAGTGAATTGCTGGGGTTGCTGGGAGAGGTACCAACCGTGGAATCTTT
TCTTGGAGAAGGAGCAGTTGACCCCAATGACCCTAACAAGGCAAATACATTAAGTCAGCTTTCA
AAGACCGAGATTTCTCTTGTCTTGGCAAGCAAATATGACATAGAGGACGGTGAAGCTATAGATA
GCCGAAGCCTCATGATAAAGACCAAGAAGCTGATAATTGATGTGATCCGGAACCAGCCAGGGAA
CACATTGACAGAAATCTTAGAGACACCAGCCACTGCGCAACAGGAGGCAGACCATGCCACAGAC
ATGGTGAGCCGTGCAATGATAGATTCCAGGACTCCAGAAGAAATGAAGCATAGCCAATCTATGA
TTGAAGATGCACAGCTGCCTCTTGAGCAGAAGAAGAGGAAAATCCAGAGGAATCTTCGGACATT
GGAACAGACTGGACACGTGTCATCCAAAAATAAATACCAAGACATTCTCAATGAGATTGCCAAG
GATATTCGAAATCAAAGAATCTATCGTAAGCTTCGAAAAGCTGAATTGGCAAAACTTCAGCAGA
CCCTGAATGCACTTAACAAGAAGGCAGCATTTTATGAAGAGCAAATCAATTATTATGACACCTA
CATAAAGACTTGTTTAGACAACTTAAAAAGAAAAAATACTCGGAGATCAATTAAACTAGATGGG
AAAGGAGAACCCAAAGGGACGAAGAGAGCGAAGCCAGTGAAGTACACTGCGGCAAAGCTGCACG
AGAAAGGCGTCCTGCTAGATATAGATGATCTTCAAACAAACCAGTTTAAGAATGTTACATTTGA
TATCATAGCTACTGAAGATGTCGGCATTTTTGATGTAAGATCAAAATTCCTTGGTGTTGAGATG
GAAAAGGTGCAACTCAATATTCAGGATTTACTTCAGATGCAATACGAAGGAGTAGCTGTAATGA
AAATGTTTGATAAGGTCAAAGTGAATGTCAACCTTCTTATATACCTGCTGAACAAGAAATTCTA
TGGCAAGTGAAGTGCCTGCAGAAGTGTCATGGATTCTGTATCATCTGGATTAGGAAATGAATTT
GTTTAATATTTTTGTTTTTAAACATGATTGAAATCACTGCTTATAAATGTGTGATTTTTTTTTA
AATGACCAAAACTGTTCTGAAGAATGTACCCAGGTGCCTTTTTGCTAATCTGATACTATAATAG
AATGAGACATAAAATGAATTAATGGAAACATATCCACGCTGTACTGTGGTATAGGTACTCTGAT
TGAAAACTTTGGACATCGTGTGATCTGTTTTAAAGTTGCGGGGTGGGGAATTTAGCTGACTAGG
GACAAACATGTAAACCTATTTTCCTATGAAAACATTTTAAATGTCCCACTTGAATAATGTAATT
CTTCATAGTTTTTTTTTTAATCTATGGATAAATGGAAACCTAATTGTTTGTAATGAATCATTTA
GACAGTTTTAAGCCCTGTCTTCTGGGAGTTATCAATTTTAAAGAGAACTTTTGTGCAATTCAAA
TGAACTTTTTATAAGTAATTGAAAATGACAACACAATAACACTTTCTGTATAAAAGTATATATT
TTATGTGATTTATTCCTACTAAATGAAAGTGCACTACTGCCTCATGTAAAGACTCTTGCACGCA
GAGCCTTTAAATGACTAAGGAACAACATAGATAGTGAGCATAGTTCCCGCCTCCACCCCTCACA
ATTTATCTGAATACTTCAATTGTGCCTCTCAATTTTTTGTAATGCTAAAAAATCAGTATCTAGA
TGGTTTTTAAACGTATTCTCTGGAAATTGTTTTATGTAAAATAAATGTTACTTAATTCCATTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007974040	(Get FASTA)	NCBI Sequence Viewer
	XP_072870769	(Get FASTA)	NCBI Sequence Viewer
	XP_072870770	(Get FASTA)	NCBI Sequence Viewer
	XP_072870771	(Get FASTA)	NCBI Sequence Viewer
	XP_072870772	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000011459.1

RefSeq Acc Id:	XP_007974040 ⟸ XM_007975849
- UniProtKB:	A0A0D9RS70 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000011459 ⟸ ENSCSAT00000013459

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000015367	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000013459.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.418.10	UniProtKB/TrEMBL
	1.20.5.190	UniProtKB/TrEMBL
	GTPase Activation - p120gap, domain 1	UniProtKB/TrEMBL
InterPro	CH-domain	UniProtKB/TrEMBL
	CH_dom_sf	UniProtKB/TrEMBL
	IQ_motif_EF-hand-BS	UniProtKB/TrEMBL
	RasGAP_C	UniProtKB/TrEMBL
	RasGAP_CS	UniProtKB/TrEMBL
	RasGAP_dom	UniProtKB/TrEMBL
	Rho_GTPase_activation_prot	UniProtKB/TrEMBL
KEGG Report	csab:103223348	UniProtKB/TrEMBL
NCBI Gene	IQGAP2	ENTREZGENE
PANTHER	RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF	UniProtKB/TrEMBL
	RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP2	UniProtKB/TrEMBL
Pfam	PF00307	UniProtKB/TrEMBL
	PF00612	UniProtKB/TrEMBL
	RasGAP	UniProtKB/TrEMBL
	RasGAP_C	UniProtKB/TrEMBL
PROSITE	PS50021	UniProtKB/TrEMBL
	PS50096	UniProtKB/TrEMBL
	RAS_GTPASE_ACTIV_1	UniProtKB/TrEMBL
	RAS_GTPASE_ACTIV_2	UniProtKB/TrEMBL
SMART	RasGAP	UniProtKB/TrEMBL
	SM00015	UniProtKB/TrEMBL
	SM00033	UniProtKB/TrEMBL
Superfamily-SCOP	RGC domain-like	UniProtKB/TrEMBL
	SSF47576	UniProtKB/TrEMBL
	SSF48350	UniProtKB/TrEMBL
UniProt	A0A0D9RS70	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI