TMEM95 (transmembrane protein 95) - Rat Genome Database

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Gene: TMEM95 (transmembrane protein 95) Chlorocebus sabaeus
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Symbol: TMEM95
Name: transmembrane protein 95
RGD ID: 18617973
Description: INVOLVED IN fusion of sperm to egg plasma membrane involved in single fertilization (inferred); ASSOCIATED WITH common variable immunodeficiency (ortholog); congenital myasthenic syndrome 2A (ortholog); dyskeratosis congenita (ortholog); FOUND IN acrosomal membrane (inferred); membrane (inferred); sperm plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sperm-egg fusion protein TMEM95
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,733,315 - 6,735,500 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,733,479 - 6,734,906 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,676,228 - 14,677,671 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TMEM95
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,733,315 - 6,735,500 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,733,479 - 6,734,906 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,676,228 - 14,677,671 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TMEM95
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,355,156 - 7,357,219 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,355,123 - 7,357,219 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,258,475 - 7,260,538 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,199,221 - 7,201,262 (+)NCBINCBI36Build 36hg18NCBI36
Celera177,284,442 - 7,286,483 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,152,556 - 7,154,597 (+)NCBIHuRef
CHM1_1177,267,272 - 7,269,313 (+)NCBICHM1_1
T2T-CHM13v2.0177,259,147 - 7,261,210 (+)NCBIT2T-CHM13v2.0
Tmem95
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,766,880 - 69,768,997 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,766,883 - 69,768,879 (-)EnsemblGRCm39 Ensembl
GRCm381169,876,054 - 69,878,171 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,876,057 - 69,878,053 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,690,186 - 69,691,607 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,690,186 - 69,691,607 (-)NCBIMGSCv36mm8
Celera1177,424,239 - 77,425,660 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.91NCBI
Tmem95
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,098,518 - 55,100,463 (-)NCBIGRCr8
mRatBN7.21054,599,799 - 54,601,746 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,599,800 - 54,601,790 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,262,256 - 59,264,203 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,750,826 - 58,752,772 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0PNS010002074.112,432 - 14,388 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,486,778 - 56,488,723 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,487,417 - 56,488,723 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,231,897 - 56,233,953 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,720,626 - 56,721,932 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1053,753,809 - 53,755,754 (-)NCBICelera
Cytogenetic Map10q24NCBI
Tmem95
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,562,723 - 9,564,818 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,562,723 - 9,564,818 (-)NCBIChiLan1.0ChiLan1.0
TMEM95
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,952,039 - 14,955,464 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,917,864 - 16,921,299 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,389,244 - 7,391,773 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,375,450 - 7,376,962 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,375,571 - 7,377,086 (+)Ensemblpanpan1.1panPan2
TMEM95
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,309,025 - 32,311,010 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,309,129 - 32,310,965 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,446,984 - 32,448,971 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,414,329 - 32,416,317 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,414,436 - 32,416,272 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,379,792 - 32,381,780 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,338,533 - 32,340,519 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,515,577 - 32,517,564 (+)NCBIUU_Cfam_GSD_1.0
Tmem95
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,173,351 - 47,175,510 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595647,735 - 649,152 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595647,735 - 649,152 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM95
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,701,052 - 52,703,216 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,701,119 - 52,704,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,919,875 - 54,922,001 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tmem95
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,976,052 - 9,977,825 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,975,903 - 9,978,343 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
71 31 20 31 31 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000009858   ⟹   ENSCSAP00000007966
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl166,733,479 - 6,734,906 (+)Ensembl
RefSeq Acc Id: XM_037987363   ⟹   XP_037843291
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605914,676,228 - 14,677,671 (-)NCBI
Protein Sequences
Protein RefSeqs XP_037843291 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007966.1
Ensembl Acc Id: ENSCSAP00000007966   ⟸   ENSCSAT00000009858
RefSeq Acc Id: XP_037843291   ⟸   XM_037987363
- UniProtKB: A0A0D9RH77 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011774 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009858.1 UniProtKB/TrEMBL
InterPro TMEM95 UniProtKB/TrEMBL
KEGG Report csab:103242291 UniProtKB/TrEMBL
NCBI Gene TMEM95 ENTREZGENE
PANTHER PTHR38808 UniProtKB/TrEMBL
  SPERM-EGG FUSION PROTEIN TMEM95 UniProtKB/TrEMBL
Pfam TMEM95 UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
UniProt A0A0D9RH77 ENTREZGENE, UniProtKB/TrEMBL