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Gene: DHRS9 (dehydrogenase/reductase 9) Chlorocebus sabaeus

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Symbol:

DHRS9

Name:

dehydrogenase/reductase 9

RGD ID:

18613246

Description:

ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (ortholog); INVOLVED IN retinoic acid biosynthetic process (ortholog); PARTICIPATES IN retinoic acid metabolic pathway; retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Birth Weight (ortholog); FOUND IN endoplasmic reticulum membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

dehydrogenase/reductase SDR family member 9; LOC103217264

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	54,611,792 - 54,641,037 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	54,614,559 - 54,641,877 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	144,893,959 - 144,920,547 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bardet-Biedl syndrome (ISO)

Birth Weight (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

9-cis-retinoic acid biosynthetic process (IEA)

androgen metabolic process (IEA)

progesterone metabolic process (IEA)

retinoic acid biosynthetic process (ISO)

steroid metabolic process (IEA)

Cellular Component

endoplasmic reticulum membrane (IEA)

Molecular Function

alcohol dehydrogenase (NAD+) activity (IEA)

all-trans-retinol dehydrogenase (NAD+) activity (IEA,ISO)

androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity (IEA)

androsterone dehydrogenase [NAD(P)+] activity (IEA)

oxidoreductase activity (IEA)

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (IEA)

protein binding (ISO)

testosterone dehydrogenase (NAD+) activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

retinoic acid metabolic pathway (ISO)

retinol metabolic pathway (ISO)

vitamin A deficiency pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

DHRS9
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	54,611,792 - 54,641,037 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	54,614,559 - 54,641,877 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	144,893,959 - 144,920,547 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

DHRS9
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	169,067,077 - 169,096,167 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	169,064,789 - 169,096,167 (+)	Ensembl			hg38	GRCh38
GRCh37	2	169,923,587 - 169,952,677 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	169,629,545 - 169,660,923 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	169,749,051 - 169,778,184	NCBI
Celera	2	163,546,627 - 163,578,019 (+)	NCBI		Celera
Cytogenetic Map	2	q31.1	NCBI
HuRef	2	161,818,234 - 161,849,556 (+)	NCBI		HuRef
CHM1_1	2	169,927,309 - 169,958,689 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	169,542,807 - 169,571,856 (+)	NCBI		T2T-CHM13v2.0

Dhrs9
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	69,210,806 - 69,233,430 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	69,210,789 - 69,234,877 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	69,380,462 - 69,403,086 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	69,380,445 - 69,404,533 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	69,218,519 - 69,241,143 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	69,181,301 - 69,203,925 (+)	NCBI		MGSCv36	mm8
Celera	2	71,045,992 - 71,068,496 (+)	NCBI		Celera
Cytogenetic Map	2	C2	NCBI
cM Map	2	40.59	NCBI

Dhrs9
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	74,553,357 - 74,579,535 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	74,555,606 - 74,581,376 (+)	Ensembl				GRCr8
mRatBN7.2	3	54,147,834 - 54,170,052 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	54,147,803 - 54,220,241 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	57,547,988 - 57,569,938 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	66,131,554 - 66,153,514 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	63,894,233 - 63,916,194 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	55,623,671 - 55,645,883 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	55,623,634 - 55,648,325 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	62,230,676 - 62,252,887 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	51,521,343 - 51,543,552 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	53,710,208 - 53,732,381 (+)	NCBI		Celera
RGSC_v3.1	3	51,417,714 - 51,439,924 (+)	NCBI
Cytogenetic Map	3	q21	NCBI

Dhrs9
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955449	5,359,617 - 5,380,267 (-)	Ensembl
ChiLan1.0	NW_004955449	5,360,486 - 5,380,279 (-)	NCBI	ChiLan1.0	ChiLan1.0

DHRS9
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	71,732,933 - 71,761,526 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	71,747,905 - 71,774,747 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	56,347,489 - 56,376,463 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	173,814,354 - 173,840,879 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	173,811,932 - 173,842,816 (+)	Ensembl			panPan2	panpan1.1

DHRS9
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	13,859,935 - 13,881,432 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	13,866,959 - 13,880,179 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	13,872,769 - 13,897,292 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	13,978,257 - 14,002,826 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	13,987,853 - 13,996,566 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	14,062,759 - 14,087,288 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	14,050,712 - 14,075,307 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	14,163,864 - 14,188,389 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dhrs9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	131,131,376 - 131,152,420 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	10,465,701 - 10,487,534 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	10,465,701 - 10,487,534 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DHRS9
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	75,507,588 - 75,534,481 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	75,507,538 - 75,533,942 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	84,800,183 - 84,823,204 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Dhrs9
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624787	6,758,478 - 6,776,238 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624787	6,751,787 - 6,776,181 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in DHRS9
559 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007965274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000013344 ⟹ ENSCSAP00000011345

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	10	54,614,559 - 54,641,877 (+)	Ensembl

RefSeq Acc Id:

XM_007965274 ⟹ XP_007963465

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	10	54,611,792 - 54,641,037 (+)	NCBI
Vero_WHO_p1.0	NW_023666040	144,893,959 - 144,920,547 (-)	NCBI

Sequence:

show sequence

GAAAATACAAAGTACACTTTTAAAACATGAAGGCTTCATAGCAGTTCATAGTCGTTCAGAGAAA
CATGTTCCACTGAGAGTGACCCAGGAGAGAGGATTACATTATTATGCCAGAAGGAAGAGGCCAC
TATGCATGCCCCATCACCAGCCTCACCCTCCTGGTCAGCCTTACAAGAGTGACACTAGATATAC
TCCAGGAGTTGGACCCACCACAGCCTGCACACTGGACTTCTTGGCTTTTATGAGCTATTCAAGA
GAGCTTTAGTCATCACGTTGTGTCACAATGGGAGTGACTCACAGAGCAAGGAGAGAACCTGAGG
ATTCCTCACACATGTAGTACTCAGAGCTCTACAGAAACCCAGGCACCTCAACCTCAAGAGGATC
AGCCTGGCCAGGGTGGCACAACTCTTCCTTCCCCGTGCACAGCAGGAAAGCTGCCGTCAGCTGA
GCAAGTCCACCAACAGTTTCTGTGTCCCACTTCATCTTTAATAAGGACACCATCTTCTTTTATT
ATACAAGAAAGGAGTGTACCTATCACACACAGGGGGAAAATGCTCTTTTGGGTGCTAGGCTTCC
TAATCCTCTGTGGTTTTCTGTGGACTCGTAAAGGAAAACTAAAGATTGCAGACATCACTGATAA
GTACATTTTTATCACTGGATGTGACTCGGGCTTTGGAAACTTGGCAGCCAGAACTTTTGATAAA
AAGGGATTTCATGTAATCGCTGCCTGTCTGACTGAATCAGGATCAACCGCTTTAAAGTCAGAAA
CCTCAGAGAGACTTCGTACTGTACTTCTGGATGTGACTGACCCAGAGAATGTCAAGAGGACTGC
CCAGTGGGTGAAGAACCAAGTTGGGGAAAAAGGTCTCTGGGGTCTGATCAATAATGCTGGTATT
CCCGGTGTGCTGGCTCCCACTGACTGGCTGACACTAGAGGACTACAGAGAACCCATTGAAGTGA
ATCTGTTTGGACTCATCAGTGTGACACTAAATATGCTTCCCTTGGTCAAGAAAGCTCAAGGGAG
AGTTATTAATGTCTCCAGTGTTGGAGGTCGCCTTGCAATCGTTGGAGGGGGCTATACTCCATCC
AAATATGCAGTGGAAGGTTTCAATGACAGCTTAAGACGGGACATGAAAGCTTTTGGTGTGCACG
TCTCATGTATTGAACCAGGATTGTTCAAAACAAACTTGGCAGATCCAGTAAAGGTAACTGAAAA
AAAACTCGCCATTTGGGAGCAGCTGTCTCCAGACATCAAACAACAATATGGAGAAGGTTACATT
GAAAAAAGTCTAGACAAACTGAAAGGCAATAAATCCTATGCGAACATGGACCTCTCTCTGGTGG
TAGAGTGCATGGACCACGCTCTAACAAGTCTCTTCCCTAAGACTCATTATGCTGTTGGAAAAGA
TGCCAAAATTTTCTGGATACCTCTGTCTCACATGCCAGCAGTTTTGCAAGACTTTTTGTTGTTG
AAACGGAAAACAGAGCTGGCTAATCCCAAGGCAGTGTGACTCAGCTAACCACAGGTGCCTGCTC
CAGGCTATGAGATTGGCCGATTTCAAGAGCACATCTCCTTTTCAACCCCATTCTTTATCTGTTC
CAACCTGGACTCATTTAGATCCTACTTATTTGGATTACAAAAGGGAGTCCCACCATTGCTGGTG
GTGTCCTAGTGTCCCTGCTCAAGTTTTCTTTGAAAAGGAGGGCTGGAATGGTACATCACACAGG
CAGGTCCTGCCATGTATGTAGGCTTTGCCTGCTTGGTATGATGTAAGGGAAATTGAAAGACTTG
CCCATTCCAAATGATCTTCACTGTGGCCTACCCTGTGCTTATGGTCCCCAGCATTTAGAATAAC
TTGTGAATGTTAAGTATCGTCTCTTATCTAAATATTAAAAGATAAGTCAAACATTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_007963465	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000011345.1

RefSeq Acc Id:	XP_007963465 ⟸ XM_007965274
- UniProtKB:	A0A0D9RRV6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000011345 ⟸ ENSCSAT00000013344

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000015245	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000013344.1	UniProtKB/TrEMBL
Gene3D-CATH	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	SDR_fam	UniProtKB/TrEMBL
KEGG Report	csab:103217264	UniProtKB/TrEMBL
NCBI Gene	LOC103217264	ENTREZGENE
PANTHER	DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 9	UniProtKB/TrEMBL
	SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C	UniProtKB/TrEMBL
Pfam	adh_short	UniProtKB/TrEMBL
PRINTS	GDHRDH	UniProtKB/TrEMBL
	SDRFAMILY	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51735	UniProtKB/TrEMBL
UniProt	A0A0D9RRV6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-12-08	DHRS9	dehydrogenase/reductase 9	LOC103217264	dehydrogenase/reductase SDR family member 9	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Annotations - SMPDB