P2RX2 (purinergic receptor P2X 2) - Rat Genome Database

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Gene: P2RX2 (purinergic receptor P2X 2) Chlorocebus sabaeus
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Symbol: P2RX2
Name: purinergic receptor P2X 2
RGD ID: 18518070
Description: ENCODES a protein that exhibits ATP binding (ortholog); cadmium ion binding (ortholog); cobalt ion binding (ortholog); INVOLVED IN behavioral response to pain (ortholog); chemical synaptic transmission (ortholog); detection of hypoxic conditions in blood by carotid body chemoreceptor signaling (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness (ortholog); autosomal dominant nonsyndromic deafness 41 (ortholog); colorectal cancer (ortholog); FOUND IN cell surface (ortholog); dendritic spine (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: P2X purinoceptor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111127,961,004 - 127,964,529 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11127,961,079 - 127,964,113 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037116,903,349 - 116,907,655 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
P2RX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111127,961,004 - 127,964,529 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11127,961,079 - 127,964,113 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037116,903,349 - 116,907,655 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
P2RX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812132,618,776 - 132,622,388 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12132,618,776 - 132,622,388 (+)EnsemblGRCh38hg38GRCh38
GRCh3712133,195,362 - 133,198,974 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612131,705,476 - 131,709,045 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412131,805,752 - 131,809,322NCBI
Celera12132,895,833 - 132,898,704 (+)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12129,940,850 - 129,978,664 (+)NCBIHuRef
CHM1_112133,014,978 - 133,018,311 (+)NCBICHM1_1
T2T-CHM13v2.012132,668,996 - 132,672,547 (+)NCBIT2T-CHM13v2.0
P2rx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395110,487,678 - 110,491,186 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5110,487,678 - 110,491,078 (-)EnsemblGRCm39 Ensembl
GRCm385110,339,812 - 110,343,320 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5110,339,812 - 110,343,212 (-)EnsemblGRCm38mm10GRCm38
MGSCv375110,768,831 - 110,772,054 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365110,580,114 - 110,583,514 (-)NCBIMGSCv36mm8
Celera5107,464,481 - 107,467,704 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map553.49NCBI
P2rx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81251,999,107 - 52,002,627 (+)NCBIGRCr8
mRatBN7.21246,338,979 - 46,342,891 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1246,339,549 - 46,342,891 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1247,515,324 - 47,518,520 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01248,120,973 - 48,124,163 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01247,181,498 - 47,184,688 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01252,397,666 - 52,401,005 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1252,397,792 - 52,401,015 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,133,143 - 54,136,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41246,485,125 - 46,488,319 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11246,352,056 - 46,355,251 (+)NCBI
Celera1247,896,140 - 47,899,334 (+)NCBICelera
Cytogenetic Map12q16NCBI
P2rx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955482419,213 - 421,583 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955482418,101 - 422,058 (-)NCBIChiLan1.0ChiLan1.0
P2RX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210140,727,913 - 140,732,757 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112140,724,426 - 140,729,274 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012129,969,793 - 129,974,399 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112134,679,826 - 134,694,613 (+)NCBIpanpan1.1PanPan1.1panPan2
P2RX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.126480,370 - 485,527 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl26482,425 - 485,502 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha26521,018 - 527,367 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.026537,116 - 543,463 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl26540,383 - 543,463 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.126480,971 - 484,056 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.026565,312 - 571,661 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.026496,140 - 502,489 (-)NCBIUU_Cfam_GSD_1.0
P2rx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118122,147,514 - 122,150,459 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366602,570,625 - 2,573,296 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366602,570,627 - 2,574,081 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P2RX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1422,854,828 - 22,858,386 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11422,854,828 - 22,858,574 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21424,390,356 - 24,393,061 (+)NCBISscrofa10.2Sscrofa10.2susScr3
P2rx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474728,020,652 - 28,023,392 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474728,019,305 - 28,023,558 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in P2RX2
48 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
65 35 18 33 33 50 20

Sequence


Ensembl Acc Id: ENSCSAT00000016685   ⟹   ENSCSAP00000016187
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl11127,961,079 - 127,964,113 (+)Ensembl
RefSeq Acc Id: XM_008005300   ⟹   XP_008003491
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111127,961,004 - 127,964,529 (+)NCBI
Vero_WHO_p1.0NW_023666037116,903,354 - 116,907,655 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008005303   ⟹   XP_008003494
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111127,961,004 - 127,964,529 (+)NCBI
Vero_WHO_p1.0NW_023666037116,903,357 - 116,907,655 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008005304   ⟹   XP_008003495
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111127,961,004 - 127,964,529 (+)NCBI
Vero_WHO_p1.0NW_023666037116,903,356 - 116,907,655 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008005305   ⟹   XP_008003496
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111127,961,004 - 127,964,529 (+)NCBI
Vero_WHO_p1.0NW_023666037116,903,353 - 116,907,655 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037994833   ⟹   XP_037850761
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666037116,903,349 - 116,907,655 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008003491 (Get FASTA)   NCBI Sequence Viewer  
  XP_008003494 (Get FASTA)   NCBI Sequence Viewer  
  XP_008003495 (Get FASTA)   NCBI Sequence Viewer  
  XP_008003496 (Get FASTA)   NCBI Sequence Viewer  
  XP_037850761 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016187.1
RefSeq Acc Id: XP_008003491   ⟸   XM_008005300
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S5P8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008003494   ⟸   XM_008005303
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S5P8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008003495   ⟸   XM_008005304
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S5P8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008003496   ⟸   XM_008005305
- Peptide Label: isoform X4
- UniProtKB: A0A0D9S5P8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000016187   ⟸   ENSCSAT00000016685
RefSeq Acc Id: XP_037850761   ⟸   XM_037994833
- Peptide Label: isoform X5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000001850 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016685.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.490.10 UniProtKB/TrEMBL
  atp-gated p2x4 ion channel UniProtKB/TrEMBL
InterPro P2X2_purnocptor UniProtKB/TrEMBL
  P2X_extracellular_dom_sf UniProtKB/TrEMBL
  P2X_purnocptor UniProtKB/TrEMBL
  P2X_RECEPTOR_CS UniProtKB/TrEMBL
NCBI Gene P2RX2 ENTREZGENE
PANTHER P2X PURINOCEPTOR UniProtKB/TrEMBL
  P2X PURINOCEPTOR 2 UniProtKB/TrEMBL
Pfam P2X_receptor UniProtKB/TrEMBL
PIRSF P2X_purinoceptor UniProtKB/TrEMBL
PRINTS P2X2RECEPTOR UniProtKB/TrEMBL
  P2XRECEPTOR UniProtKB/TrEMBL
PROSITE P2X_RECEPTOR UniProtKB/TrEMBL
UniProt A0A0D9S5P8 ENTREZGENE, UniProtKB/TrEMBL