FANCF (FA complementation group F) - Rat Genome Database

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Gene: FANCF (FA complementation group F) Chlorocebus sabaeus
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Symbol: FANCF
Name: FA complementation group F
RGD ID: 18470046
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN DNA damage response (ortholog); ovarian follicle development (ortholog); protein ubiquitination (ortholog); ASSOCIATED WITH adenocarcinoma in situ (ortholog); breast cancer (ortholog); disease of cellular proliferation (ortholog); FOUND IN chromatin (inferred); Fanconi anaemia nuclear complex (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Fanconi anemia complementation group F; Fanconi anemia group F protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1142,377,150 - 42,381,653 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl142,378,883 - 42,380,007 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038139,681,806 - 139,685,541 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FANCF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1142,377,150 - 42,381,653 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl142,378,883 - 42,380,007 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038139,681,806 - 139,685,541 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FANCF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381122,622,533 - 22,625,823 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1122,622,533 - 22,625,823 (-)EnsemblGRCh38hg38GRCh38
GRCh371122,644,079 - 22,647,369 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361122,600,655 - 22,603,963 (-)NCBINCBI36Build 36hg18NCBI36
Build 341122,600,654 - 22,603,963NCBI
Celera1122,777,941 - 22,781,250 (-)NCBICelera
Cytogenetic Map11p14.3NCBI
HuRef1122,327,266 - 22,330,575 (-)NCBIHuRef
CHM1_11122,643,695 - 22,647,004 (-)NCBICHM1_1
T2T-CHM13v2.01122,743,288 - 22,746,579 (-)NCBIT2T-CHM13v2.0
Fancf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39751,510,325 - 51,512,015 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl751,510,325 - 51,512,015 (-)EnsemblGRCm39 Ensembl
GRCm38751,860,577 - 51,862,267 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl751,860,577 - 51,862,267 (-)EnsemblGRCm38mm10GRCm38
MGSCv37759,115,947 - 59,117,637 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36759,115,947 - 59,117,624 (-)NCBIMGSCv36mm8
Celera749,233,676 - 49,235,406 (-)NCBICelera
Cytogenetic Map7B4NCBI
cM Map732.87NCBI
Fancf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81110,585,054 - 110,587,870 (-)NCBIGRCr8
mRatBN7.21101,449,120 - 101,451,936 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1101,450,389 - 101,451,923 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1106,857,994 - 106,860,810 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01115,329,884 - 115,332,700 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01108,633,029 - 108,635,845 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01107,229,516 - 107,232,321 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1107,231,292 - 107,232,305 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01108,272,291 - 108,274,234 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41101,664,895 - 101,666,720 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera195,615,737 - 95,618,542 (-)NCBICelera
Cytogenetic Map1q22NCBI
Fancf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554763,067,689 - 3,068,728 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554763,067,491 - 3,069,637 (-)NCBIChiLan1.0ChiLan1.0
FANCF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2924,912,428 - 24,915,178 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11124,876,586 - 24,881,158 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01122,634,301 - 22,637,885 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11122,542,426 - 22,546,147 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1122,544,052 - 22,545,176 (-)Ensemblpanpan1.1panPan2
FANCF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12144,253,308 - 44,256,221 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2144,255,134 - 44,256,618 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2143,728,664 - 43,731,582 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02145,370,190 - 45,373,442 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12144,370,738 - 44,373,650 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02144,542,654 - 44,545,584 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02144,935,521 - 44,938,442 (-)NCBIUU_Cfam_GSD_1.0
Fancf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494740,625,542 - 40,630,998 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366543,298,193 - 3,301,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FANCF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl236,884,777 - 36,885,856 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1236,884,701 - 36,886,661 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2240,095,250 - 40,097,471 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Fancf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476613,583,664 - 13,585,684 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FANCF
109 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008004110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000019410   ⟹   ENSCSAP00000018829
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl142,378,883 - 42,380,007 (+)Ensembl
RefSeq Acc Id: XM_008004110   ⟹   XP_008002301
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1142,377,150 - 42,381,653 (+)NCBI
Vero_WHO_p1.0NW_023666038139,681,806 - 139,685,541 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008002301 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018829.1
RefSeq Acc Id: XP_008002301   ⟸   XM_008004110
- UniProtKB: A0A0D9SD90 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000018829   ⟸   ENSCSAT00000019410


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000019320 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000019410.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.490 UniProtKB/TrEMBL
InterPro FANCF UniProtKB/TrEMBL
  FANCF_C_sf UniProtKB/TrEMBL
KEGG Report csab:103238775 UniProtKB/TrEMBL
NCBI Gene FANCF ENTREZGENE
PANTHER FANCONI ANEMIA GROUP F PROTEIN UniProtKB/TrEMBL
  PTHR14449 UniProtKB/TrEMBL
Pfam FANCF UniProtKB/TrEMBL
UniProt A0A0D9SD90 ENTREZGENE, UniProtKB/TrEMBL