UCP3 (uncoupling protein 3) - Rat Genome Database

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Gene: UCP3 (uncoupling protein 3) Chlorocebus sabaeus
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Symbol: UCP3
Name: uncoupling protein 3
RGD ID: 18441176
Description: ENCODES a protein that exhibits calcium ion transmembrane transporter activity (ortholog); oxidative phosphorylation uncoupler activity (ortholog); INVOLVED IN cellular response to hormone stimulus (ortholog); fatty acid metabolic process (ortholog); response to activity (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); congestive heart failure (ortholog); coronary restenosis (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial uncoupling protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1165,269,611 - 65,279,079 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl165,269,607 - 65,278,807 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604360,587,459 - 60,596,911 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UCP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1165,269,611 - 65,279,079 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl165,269,607 - 65,278,807 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604360,587,459 - 60,596,911 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
UCP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381174,000,277 - 74,009,085 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1174,000,277 - 74,009,085 (-)EnsemblGRCh38hg38GRCh38
GRCh371173,711,322 - 73,720,130 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361173,388,985 - 73,397,778 (-)NCBINCBI36Build 36hg18NCBI36
Build 341173,392,374 - 73,397,778NCBI
Celera1171,018,129 - 71,027,086 (-)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1170,007,226 - 70,016,183 (-)NCBIHuRef
CHM1_11173,595,177 - 73,604,136 (-)NCBICHM1_1
T2T-CHM13v2.01173,929,606 - 73,938,415 (-)NCBIT2T-CHM13v2.0
Ucp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397100,122,198 - 100,135,639 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7100,122,197 - 100,135,639 (+)EnsemblGRCm39 Ensembl
GRCm387100,472,991 - 100,486,432 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7100,472,990 - 100,486,432 (+)EnsemblGRCm38mm10GRCm38
MGSCv377107,621,500 - 107,634,941 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367100,347,073 - 100,360,514 (+)NCBIMGSCv36mm8
Celera7100,810,580 - 100,824,026 (+)NCBICelera
Cytogenetic Map7E2NCBI
cM Map754.36NCBI
Ucp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81164,227,910 - 164,240,893 (+)NCBIGRCr8
mRatBN7.21154,815,777 - 154,828,764 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,815,777 - 154,828,762 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1162,810,789 - 162,823,741 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,990,890 - 170,003,842 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,864,787 - 162,877,739 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01165,482,912 - 165,495,895 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1165,482,155 - 165,496,206 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,683,566 - 171,697,139 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41157,896,001 - 157,909,608 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11157,974,793 - 157,988,399 (+)NCBI
Celera1152,898,320 - 152,911,676 (+)NCBICelera
RH 3.4 Map11258.1RGD
Cytogenetic Map1q32NCBI
Ucp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541417,558,889 - 17,578,737 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541417,558,889 - 17,578,108 (+)NCBIChiLan1.0ChiLan1.0
UCP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2974,941,880 - 74,953,797 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11175,986,899 - 75,998,075 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01169,072,143 - 69,085,424 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11172,380,180 - 72,389,274 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,380,180 - 72,389,274 (-)Ensemblpanpan1.1panPan2
UCP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12124,272,522 - 24,290,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2124,277,896 - 24,288,639 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2124,049,763 - 24,055,700 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02124,484,075 - 24,496,484 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2124,484,070 - 24,496,484 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12124,284,466 - 24,290,404 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02124,484,328 - 24,490,265 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02124,399,875 - 24,405,814 (+)NCBIUU_Cfam_GSD_1.0
Ucp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494761,482,972 - 61,496,412 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364983,082,575 - 3,095,737 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364983,082,575 - 3,095,739 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl98,378,021 - 8,386,211 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.198,378,023 - 8,389,452 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.299,167,483 - 9,178,955 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9p21-p24NCBI

Variants

.
Variants in UCP3
274 total Variants

Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
44 24 18 22 22 40 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008020126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000002079   ⟹   ENSCSAP00000000408
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl165,269,607 - 65,278,807 (-)Ensembl
RefSeq Acc Id: XM_008020126   ⟹   XP_008018317
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1165,269,611 - 65,279,079 (-)NCBI
Vero_WHO_p1.0NW_02366604360,587,459 - 60,596,911 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008018317 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000408
  ENSCSAP00000000408.1
RefSeq Acc Id: XP_008018317   ⟸   XM_008020126
- UniProtKB: A0A0D9QVL9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000000408   ⟸   ENSCSAT00000002079


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004048 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002079.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro Mit_carrier UniProtKB/TrEMBL
  Mito_Metabolite_Transporter UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/TrEMBL
KEGG Report csab:103248027 UniProtKB/TrEMBL
NCBI Gene UCP3 ENTREZGENE
PANTHER MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED UniProtKB/TrEMBL
  MITOCHONDRIAL UNCOUPLING PROTEIN 3 UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/TrEMBL
PRINTS MTUNCOUPLING UniProtKB/TrEMBL
PROSITE SOLCAR UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/TrEMBL
UniProt A0A0D9QVL9 ENTREZGENE, UniProtKB/TrEMBL