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Gene: Snw1 (SNW domain containing 1) Mus musculus

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Symbol:

Snw1

Name:

SNW domain containing 1

RGD ID:

1624001

MGI Page

MGI

Description:

Predicted to enable several functions, including Notch binding activity; nuclear receptor binding activity; and transcription coregulator activity. Involved in cellular response to retinoic acid and positive regulation of neurogenesis. Acts upstream of or within skeletal muscle cell differentiation. Predicted to be located in chromatin; nuclear matrix; and nuclear speck. Predicted to be part of SMAD protein complex; U2-type catalytic step 2 spliceosome; and cyclin/CDK positive transcription elongation factor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer and pancreatic cancer. Orthologous to human SNW1 (SNW domain containing 1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

2310008B08Rik; AW048543; MGC55033; NCoA; NCoA-62; nuclear protein SkiP; S; SKI interacting protein; ski-interacting protein; Skiip; SKIP; SN; SNW domain-containing protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SNW1 (SNW domain containing 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Snw1 (SNW domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Snw1 (SNW domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SNW1 (SNW domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SNW1 (SNW domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Snw1 (SNW domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SNW1 (SNW domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SNW1 (SNW domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Snw1 (SNW domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SNW1 (SNW domain containing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Rattus norvegicus (Norway rat):	Snw1 (SNW domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	snw1 (SNW domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	Bx42	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PRP45	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	skp-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	snw1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Related Pseudogenes:

Gm18247 Gm4810 Gm4954 Gm5971 Gm6172 Gm9448

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	87,496,680 - 87,519,069 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	87,495,845 - 87,519,044 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	87,449,910 - 87,472,299 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	87,449,075 - 87,472,274 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	88,790,860 - 88,813,249 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	88,339,401 - 88,349,540 (-)	NCBI		MGSCv36	mm8
Celera	12	88,914,532 - 88,936,919 (-)	NCBI		Celera
Cytogenetic Map	12	D2	NCBI
cM Map	12	41.67	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain Injuries (ISO)

breast cancer (ISO)

breast carcinoma (ISO)

hepatocellular carcinoma (ISO)

Optic Nerve Injuries (ISO)

pancreatic cancer (ISO)

sciatic neuropathy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

Aroclor 1254 (EXP)

atrazine (ISO)

benzo[a]pyrene (EXP)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

caffeine (ISO)

carnosic acid (EXP)

casticin (EXP)

chlorpyrifos (EXP)

choline (EXP)

cobalt dichloride (ISO)

Cuprizon (ISO)

cycloheximide (ISO)

cyclosporin A (ISO)

deoxynivalenol (EXP,ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

doxorubicin (ISO)

enzalutamide (ISO)

enzyme inhibitor (ISO)

folic acid (EXP)

FR900359 (ISO)

glycidol (ISO)

glyphosate (ISO)

indole-3-methanol (ISO)

ivermectin (ISO)

L-methionine (EXP)

lead(0) (ISO)

methoxychlor (EXP)

mono(2-ethylhexyl) phthalate (ISO)

ozone (ISO)

phenobarbital (ISO)

resveratrol (ISO)

serpentine asbestos (EXP)

sunitinib (ISO)

tetrahydropalmatine (ISO)

thiram (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to retinoic acid (IDA,ISO)

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ISO,ISS)

mRNA splicing, via spliceosome (ISO,ISS)

negative regulation of DNA-templated transcription (ISO)

negative regulation of transcription by RNA polymerase II (ISO,ISS)

positive regulation by host of viral transcription (ISO)

positive regulation of mRNA splicing, via spliceosome (ISO,ISS)

positive regulation of neurogenesis (IDA)

positive regulation of transcription by RNA polymerase II (ISO,ISS)

positive regulation of transforming growth factor beta receptor signaling pathway (ISO,ISS)

positive regulation of vitamin D receptor signaling pathway (ISO)

regulation of retinoic acid receptor signaling pathway (ISO,ISS)

regulation of vitamin D receptor signaling pathway (ISO,ISS)

retinoic acid receptor signaling pathway (ISO,ISS)

Schwann cell proliferation (ISO)

skeletal muscle cell differentiation (IMP)

Cellular Component

catalytic step 2 spliceosome (ISO)

chromatin (ISO)

cyclin/CDK positive transcription elongation factor complex (ISO,ISS)

nuclear body (ISO)

nuclear matrix (ISO,ISS)

nuclear speck (ISO)

nucleoplasm (ISO,TAS)

nucleus (ISO,ISS)

SMAD protein complex (ISO)

spliceosomal complex (ISO)

U2-type catalytic step 2 spliceosome (ISO,ISS)

Molecular Function

enzyme binding (ISO)

Notch binding (ISO)

nuclear androgen receptor binding (ISO)

nuclear receptor binding (ISO,ISS)

nuclear retinoic acid receptor binding (ISO,ISS)

nuclear vitamin D receptor binding (ISO,ISS)

protein binding (IPI,ISO)

SMAD binding (ISO,ISS)

transcription coactivator activity (ISO,ISS)

transcription corepressor activity (ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

Notch signaling pathway (IEA)

spliceosome pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Splicing and beyond: the many faces of the Prp19 complex.	Chanarat S and Strasser K, Biochim Biophys Acta. 2013 Oct;1833(10):2126-34. doi: 10.1016/j.bbamcr.2013.05.023. Epub 2013 Jun 3.
2.	Up-regulation of ski-interacting protein in rat brain cortex after traumatic brain injury.	Chen J, etal., J Mol Histol. 2013 Feb;44(1):1-10. doi: 10.1007/s10735-012-9444-9. Epub 2012 Sep 11.
3.	Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.	Couch FJ, etal., Cancer Epidemiol Biomarkers Prev. 2010 Jan;19(1):251-7. doi: 10.1158/1055-9965.EPI-09-0629.
4.	High SKIP expression is correlated with poor prognosis and cell proliferation of hepatocellular carcinoma.	Liu G, etal., Med Oncol. 2013;30(3):537. doi: 10.1007/s12032-013-0537-4. Epub 2013 May 22.
5.	Expression and prognostic role of SKIP in human breast carcinoma.	Liu X, etal., J Mol Histol. 2014 Apr;45(2):169-80. doi: 10.1007/s10735-013-9546-z. Epub 2013 Oct 23.
6.	Variation in genes required for normal mitosis and risk of breast cancer.	Olson JE, etal., Breast Cancer Res Treat. 2010 Jan;119(2):423-30. Epub 2009 Apr 18.
7.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Spatiotemporal expression of SKIP after rat sciatic nerve crush.	Wang Y, etal., Neurochem Res. 2013 Apr;38(4):857-65. doi: 10.1007/s11064-013-0990-7. Epub 2013 Feb 7.
10.	Up-regulation of SKIP relates to retinal ganglion cells apoptosis after optic nerve crush in vivo.	Wu Y, etal., J Mol Histol. 2014 Dec;45(6):715-21. doi: 10.1007/s10735-014-9589-9. Epub 2014 Jul 30.

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10725249	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:12529369	PMID:12904583	PMID:14610273	PMID:14681479
PMID:14729942	PMID:15878163	PMID:16141072	PMID:16141073	PMID:17592128	PMID:18287559	PMID:18799693	PMID:19934264	PMID:20059953	PMID:20360068	PMID:20362541	PMID:21267068
PMID:22147266	PMID:26496610	PMID:26939788	PMID:28671696	PMID:31927035	PMID:32325033	PMID:33388413	PMID:35449600	PMID:36878279

Genomics

Comparative Map Data

Snw1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	87,496,680 - 87,519,069 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	87,495,845 - 87,519,044 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	87,449,910 - 87,472,299 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	87,449,075 - 87,472,274 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	88,790,860 - 88,813,249 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	88,339,401 - 88,349,540 (-)	NCBI		MGSCv36	mm8
Celera	12	88,914,532 - 88,936,919 (-)	NCBI		Celera
Cytogenetic Map	12	D2	NCBI
cM Map	12	41.67	NCBI

SNW1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	77,717,599 - 77,761,156 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	77,717,599 - 77,761,207 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	78,183,942 - 78,227,499 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	77,253,695 - 77,297,250 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	77,253,696 - 77,297,250	NCBI
Celera	14	58,222,440 - 58,266,009 (-)	NCBI		Celera
Cytogenetic Map	14	q24.3	NCBI
HuRef	14	58,349,919 - 58,393,992 (-)	NCBI		HuRef
CHM1_1	14	78,123,415 - 78,166,965 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	71,926,934 - 71,971,187 (-)	NCBI		T2T-CHM13v2.0

Snw1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	112,826,374 - 112,850,459 (-)	NCBI		GRCr8
mRatBN7.2	6	107,095,450 - 107,119,536 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	107,095,457 - 107,119,536 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	107,264,352 - 107,288,363 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	107,563,169 - 107,587,180 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	106,932,867 - 106,956,881 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	111,483,698 - 111,507,782 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	111,483,703 - 111,507,782 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	120,764,412 - 120,788,496 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	111,688,742 - 111,712,826 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	104,915,183 - 104,939,184 (-)	NCBI		Celera
Cytogenetic Map	6	q31	NCBI

Snw1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	1,561,568 - 1,601,492 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	1,561,562 - 1,601,492 (-)	NCBI	ChiLan1.0	ChiLan1.0

SNW1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	78,803,745 - 78,848,492 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	78,020,250 - 78,064,997 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	58,271,830 - 58,315,773 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	77,472,381 - 77,517,314 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	77,472,387 - 77,517,315 (-)	Ensembl	panpan1.1		panPan2

SNW1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	50,478,924 - 50,512,360 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	50,479,338 - 50,512,243 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	50,166,344 - 50,199,802 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	50,713,229 - 50,746,681 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	50,713,236 - 50,746,564 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	50,375,212 - 50,408,764 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	50,398,347 - 50,432,000 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	50,797,025 - 50,830,653 (-)	NCBI		UU_Cfam_GSD_1.0

Snw1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	25,537,625 - 25,574,412 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	6,494,562 - 6,531,600 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	6,494,556 - 6,531,297 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SNW1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	100,718,036 - 100,749,356 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	100,718,298 - 100,749,414 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SNW1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	54,976,597 - 55,020,051 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	54,977,083 - 55,019,988 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	43,163,503 - 43,207,653 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Snw1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	24,161,662 - 24,191,937 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	24,161,974 - 24,191,943 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Snw1
676 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	363
Count of miRNA genes:	266
Interacting mature miRNAs:	291
Transcripts:	ENSMUST00000021428
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300883	Ath21_m	atherosclerosis 21 (mouse)			Not determined		12	85961579	119961683	Mouse
39128213	Lwq23_m	liver weight QTL 10 (mouse)					12	80956708	113383533	Mouse
14746976	Manh73_m	mandible shape 73 (mouse)					12	65857131	99857131	Mouse
27226776	Tibl6_m	tibia length 6, 5 week (mouse)					12	60646786	92666774	Mouse
1300633	Cdcs7_m	cytokine deficiency colitis susceptibility 7 (mouse)			Not determined		12	64689083	98689229	Mouse
1301337	Cdcs8_m	cytokine deficiency colitis susceptibility 8 (mouse)			Not determined		12	64689083	98689229	Mouse
25823169	Hrsq8_m	host response to SARS QTL 8, log titer (mouse)					12	81696245	108495368	Mouse
27226771	Tibl14_m	tibia length 14, 10 week (mouse)					12	68346774	98766259	Mouse
4142002	Tbqt3_m	tibia bone quality traits 3 (mouse)			Not determined		12	35285496	109936243	Mouse
4141610	Tailaq1_m	tail length adjusted QTL 1 (mouse)			Not determined			80956708	113383533	Mouse
4141738	Tgq23_m	triglyceride QTL 23 (mouse)			Not determined			72112877	106112877	Mouse
13207568	Tcq14_m	total cholesterol QTL 14 (mouse)					12	11660001	97176774	Mouse
13524846	Ppiq11_m	prepulse inhibition QTL 11 (mouse)					12	82666396	116666396	Mouse
10412156	Nociq3_m	nociceptive sensitivity inflammatory QTL 3 (mouse)			Not determined		12	86396075	114831653	Mouse
1301879	Insq10_m	insulin QTL 10 (mouse)			Not determined		12	83532075	117532224	Mouse
13524842	Ppiq10a_m	prepulse inhibition QTL 10a (mouse)					12	77512220	111512220	Mouse
1301046	Par3_m	pulmonary adenoma resistance 3 (mouse)			Not determined		12	63956708	97956883	Mouse
1301492	Dbsty3_m	diabesity 3 (mouse)			Not determined		12	83532075	117532224	Mouse
4141335	W6q10_m	weight 6 weeks QTL 10 (mouse)			Not determined			80956708	113383533	Mouse
1301689	Skull18_m	skull morphology 18 (mouse)			Not determined		12	73887422	107887526	Mouse
10043895	Bw20_m	body weight QTL 20 (mouse)			Not determined		12	62308252	96308252	Mouse
27226797	Scvln19_m	sacral vertebrae length 2, 16 week (mouse)					12	62146786	99466259	Mouse
1357479	Splwt1_m	spleen weight 1 (mouse)			Not determined		12	41693175	90887526	Mouse
1301926	Adip6_m	adiposity 6 (mouse)			Not determined		12	73887422	107887526	Mouse
10043948	Pbft6_m	percent body fat 6 (mouse)			Not determined		12	61205427	95205427	Mouse
27226793	Feml10_m	femur length 10, 5 week (mouse)					12	68346774	113363620	Mouse
1301476	Pbwg12_m	postnatal body weight growth 12 (mouse)			Not determined		12	62040164	96040364	Mouse
27226728	Tibl20_m	tibia length 20, 16 week (mouse)					12	59146786	93866774	Mouse
4142401	Egq10_m	early growth QTL 10 (mouse)			Not determined			80956708	113383533	Mouse
13524849	Ppiq11a_m	prepulse inhibition QTL 11a (mouse)					12	80989143	114989143	Mouse

Markers in Region

D19242

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	12	87,449,982 - 87,450,136	UniSTS	GRCm38
MGSCv37	12	88,790,932 - 88,791,086	UniSTS	GRCm37
Celera	12	88,914,604 - 88,914,758	UniSTS
Cytogenetic Map	12	E	UniSTS
Cytogenetic Map	12	D2	UniSTS
Whitehead_YAC	12		UniSTS

AW048543

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	12	87,450,031 - 87,450,175	UniSTS	GRCm38
MGSCv37	12	88,790,981 - 88,791,125	UniSTS	GRCm37
Celera	12	88,914,653 - 88,914,797	UniSTS
Cytogenetic Map	12	D2	UniSTS
Cytogenetic Map	12	E	UniSTS
Whitehead/MRC_RH	12	808.9	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_025507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AK009218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK012384	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK166163	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK167695	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AX775977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AX775979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC049245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CT030249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000021428 ⟹ ENSMUSP00000021428

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	87,496,680 - 87,519,044 (-)	Ensembl
GRCm38.p6 Ensembl	12	87,449,910 - 87,472,274 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000222579

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	87,495,845 - 87,500,927 (-)	Ensembl
GRCm38.p6 Ensembl	12	87,449,075 - 87,454,157 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000223119

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	87,518,561 - 87,519,039 (-)	Ensembl
GRCm38.p6 Ensembl	12	87,471,791 - 87,472,269 (-)	Ensembl

RefSeq Acc Id:

NM_025507 ⟹ NP_079783

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	12	87,496,680 - 87,519,069 (-)	NCBI
GRCm38	12	87,449,910 - 87,472,299 (-)	ENTREZGENE
MGSCv37	12	88,790,860 - 88,813,249 (-)	RGD
Celera	12	88,914,532 - 88,936,919 (-)	RGD
cM Map	12		ENTREZGENE

Sequence:

show sequence

GGCGACGTTGTGGCCTGCGCAGGAAGAAGCGGAAGAAGATGGCGCTCACCAGCTTTTTACCTGC
GCCTACTCAGCTGTCTCAGGACCAACTTGAAGCTGAAGAAAGGGCAAGATCTCAGAGATCACTG
CAGACCTCTCTGGTCTCCTCTCGAAGGGAGCCTCCCCCATACGGATATAGGAAAGGCTGGATTC
CAAGACTATTAGAGGATTTTGGAGATGGAGGTGCTTTCCCAGAAATCCATGTGGCCCAGTATCC
TCTGGATATGGGGCGAAAGAAAAAAATGTCGAATGCTCTGGCCATTCAGGTGGATCCTGAAGGG
AAAATTAAGTATGATGCAATTGCTCGGCAGGGACAGTCCAAAGACAAGGTCATTTACAGCAAAT
ACACTGACCTGGTTCCTAAGGAGGTTATGAATGCAGATGACCCAGACCTGCAACGGCCCGATGA
AGAGGCAATTAAAGAGATAACAGAAAAGACTAGAGTTGCCTTGGAGAAATCTGTGTCGCAGAAG
GTTGCTGCAGCCATGCCAGTTCGTGCAGCTGACAAGCTGGCTCCTGCTCAGTATATCCGCTACA
CACCATCTCAGCAAGGAGTAGCATTCAATTCTGGAGCTAAACAGAGGGTCATTCGGATGGTAGA
AATGCAGAAAGACCCAATGGAGCCTCCAAGATTCAAGATTAATAAGAAAATTCCCCGGGGACCA
CCGTCTCCTCCTGCACCTGTAATGCACTCTCCTAGTCGGAAGATGACTGTAAAGGAACAACAAG
AGTGGAAGATCCCGCCTTGTATTTCCAACTGGAAGAACGCTAAGGGGTATACGATCCCATTAGA
TAAACGGCTGGCTGCTGATGGAAGAGGACTTCAGACTGTCCACATAAATGAAAATTTTGCCAAA
CTGGCTGAAGCGCTCTACATTGCTGATCGGAAGGCTCGTGAAGCGGTGGAAATGCGAGCCCAGG
TAGAGAGAAAGATGGCTCAAAAAGAAAAGGAGAAACATGAAGAGAAACTTAGAGAAATGGCCCA
GAAAGCCAGAGAAAGGAGAGCTGGAATCAAAACCCACGTGGAGAAAGAGGATGGAGAGGCCCGT
GAGAGAGATGAAATCCGTCATGACAGGCGAAAAGAGAGACAGCATGACCGGAACCTTTCCAGGG
CAGCTCCTGATAAGAGGTCAAAACTACAGAGAAATGAAAATCGAGACATCAGTGAAGTCATTGC
TCTTGGTGTGCCCAATCCTCGAACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAA
TCCAAGGGTATGGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTACAATGTTTATGATCAAG
CCTGGAGAGGTGGGAAAGATATGGCCCAGAGCATCTACAGGCCCAGTAAAAATCTGGACAAGGA
CATGTATGGTGATGACCTGGAAGCCAGGATAAAGACCAACAGATTTGTTCCTGATAAGGAGTTT
TCTGGATCAGACCGCAAACAGAGAGGCCGAGAAGGACCAGTGCAGTTTGAGGAGGATCCTTTTG
GTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCACGGTGGTTCTAAAAGACCCTCTGATAGCAG
TCGCCCCAAGGAACATGAGCATGAAGGCAAGAAGCGGAGGAAAGAGTAGAGGGACCTCTTAAAA
CTAAATCTGACATATGCAGCAGAGGACTGCCTGGTCTGGCCTCATTGTGAACAGATGTCCCCAC
CCCCTCCAGACACTTGAGACTCCAGGGAATAGGGCGTCCTAGTGGGTGGGGGTGGGGACATCCT
CTTGGAAATGGGGGAGGAGGAATGGGATGAGGAATCATCAGAGAGATGACCAGGAGGGAGATAA
AGACTGGACTGTTAAAAAAAAAAAAAAGATTAAAAAATCTCGATGATAGATCCCAGCACTCCTT
TTCATTCTGGGATGTAGGGGCATTGATTATTCTATTTCGGAGTAGTTTTTTTATATGGAATGGG
GTTATGTTTGTGCTTCTCCAATCTTGCAGCACTTAGAAATACCACTGCCCCACACAGAATTGAG
ATTCCTTCCTTGTGTGTGACACTAATCCAGCTGTAACCTTTTCTGTAAACGTTATGAATAACCT
CACCTCAAATGGTGAGTGGGCTAATGTTCACACACTGGAGCTCTGTCAACTGCATTTGCCCTGT
GTGCTTCTCCACCGCGCCATGGGGAACTAAGGTCTTGCTTAGTGCACCTCATTTCAAATAAAAA
CGTGTAGAAAAAGTCTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_079783	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH49245	(Get FASTA)	NCBI Sequence Viewer
	BAB26144	(Get FASTA)	NCBI Sequence Viewer
	BAB28203	(Get FASTA)	NCBI Sequence Viewer
	BAE38605	(Get FASTA)	NCBI Sequence Viewer
	CAE11688	(Get FASTA)	NCBI Sequence Viewer
	CAE11689	(Get FASTA)	NCBI Sequence Viewer
	EDL02956	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000021428
	ENSMUSP00000021428.8
GenBank Protein	Q9CSN1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_079783 ⟸ NM_025507

- UniProtKB:

Q9CSN1 (UniProtKB/Swiss-Prot), A0A0B4J1E2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALTSFLPAPTQLSQDQLEAEERARSQRSLQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAF
PEIHVAQYPLDMGRKKKMSNALAIQVDPEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNAD
DPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGA
KQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKN
AKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKH
EEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNE
NRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIY
RPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRKQRGREGPVQFEEDPFGLDKFLEEAKQHG
GSKRPSDSSRPKEHEHEGKKRRKE

hide sequence

Ensembl Acc Id:

ENSMUSP00000021428 ⟸ ENSMUST00000021428

Protein Domains

SKI-interacting protein SKIP SNW

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9CSN1-F1-model_v2	AlphaFold	Q9CSN1	1-536	view protein structure

Promoters

RGD ID:

8678898

Promoter ID:

EPDNEW_M17480

Type:

initiation region

Name:

Snw1_1

Description:

Mus musculus SNW domain containing 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	12	87,472,279 - 87,472,339	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1913604	AgrOrtholog
Ensembl Genes	ENSMUSG00000021039	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000021428	ENTREZGENE
	ENSMUST00000021428.9	UniProtKB/TrEMBL
InterPro	SKI-int_prot_SKIP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SKI-int_prot_SKIP_SNW-dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:66354	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1913604	ENTREZGENE
NCBI Gene	66354	ENTREZGENE
PANTHER	PTHR12096	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SNW DOMAIN-CONTAINING PROTEIN 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	SKIP_SNW	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Snw1	PhenoGen
UniProt	A0A0B4J1E2	ENTREZGENE, UniProtKB/TrEMBL
	Q3TM37_MOUSE	UniProtKB/TrEMBL
	Q80VH1_MOUSE	UniProtKB/TrEMBL
	Q9CSN1	ENTREZGENE
	Q9CV75_MOUSE	UniProtKB/TrEMBL
	SNW1_MOUSE	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)