Tcim (transcriptional and immune response regulator)

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Gene: Tcim (transcriptional and immune response regulator) Mus musculus

Analyze

Symbol:

Tcim

Name:

transcriptional and immune response regulator

RGD ID:

1623193

MGI Page

MGI

Description:

Predicted to enable Notch binding activity. Acts upstream of or within regulation of hemopoiesis. Located in cytoplasm and nucleus. Is expressed in lower jaw molar; nasal epithelium; olfactory epithelium; and upper jaw molar. Orthologous to human TCIM (transcriptional and immune response regulator).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1110065B09Rik; 1810011O10Rik; AW121743; AW321058; RIKEN cDNA 1810011O10 gene; thyroid cancer-1; uncharacterized protein C8orf4 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	24,927,188 - 24,928,962 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	24,927,196 - 24,929,000 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	24,437,172 - 24,438,946 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	24,437,180 - 24,438,984 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	25,548,088 - 25,549,418 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	25,903,161 - 25,904,491 (-)	NCBI		MGSCv36	mm8
Celera	8	25,921,731 - 25,923,061 (-)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI
cM Map	8	12.47	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hepatocellular carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (EXP)

1,2-dimethylhydrazine (EXP)

1-naphthyl isothiocyanate (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

3,3',5-triiodo-L-thyronine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

bromobenzene (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carmustine (ISO)

chlordecone (EXP)

chlorpyrifos (EXP)

chromium(6+) (ISO)

cisplatin (ISO)

clobetasol (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dioxygen (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (EXP)

folic acid (EXP,ISO)

formaldehyde (ISO)

fulvestrant (ISO)

gentamycin (ISO)

leflunomide (ISO)

Licochalcone B (ISO)

lidocaine (ISO)

lipopolysaccharide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

nickel dichloride (ISO)

niclosamide (ISO)

nitrofen (ISO)

ozone (EXP)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

perfluorooctanoic acid (ISO)

phenylmercury acetate (ISO)

quercetin (ISO)

raloxifene (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sulforaphane (ISO)

tamoxifen (ISO)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (ISO)

trichloroethene (ISO)

trichostatin A (ISO)

triclosan (ISO)

urethane (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA)

cellular response to heat (ISO,ISS)

endothelial cell activation involved in immune response (IBA,ISO,ISS)

negative regulation of apoptotic process (IEA,ISO)

negative regulation of Notch signaling pathway (IBA,ISO)

positive regulation of non-canonical NF-kappaB signal transduction (ISO)

positive regulation of protein kinase A signaling (ISO)

positive regulation of protein kinase C activity (IEA,ISO)

regulation of cell cycle G1/S phase transition (ISO,ISS)

regulation of hemopoiesis (IDA)

Cellular Component

cytoplasm (IDA,ISO)

cytosol (IBA,ISO)

nuclear speck (ISO,ISS)

nucleolus (ISO,ISS)

nucleoplasm (ISO)

nucleus (IBA,IDA,ISO,ISS)

plasma membrane (IEA,ISO)

Molecular Function

Notch binding (IBA,IEA,ISO)

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal erythrocyte morphology (IAGP)

abnormal hemopoiesis (IAGP)

abnormal mononuclear cell morphology (IAGP)

decreased mean corpuscular hemoglobin (IAGP)

decreased mean corpuscular volume (IAGP)

increased common myeloid progenitor cell number (IAGP)

increased eosinophil cell number (IAGP)

increased erythrocyte cell number (IAGP)

increased erythroid progenitor cell number (IAGP)

increased granulocyte monocyte progenitor cell number (IAGP)

increased hematopoietic stem cell number (IAGP)

increased leukocyte cell number (IAGP)

increased lymphocyte cell number (IAGP)

increased monocyte cell number (IAGP)

increased neutrophil cell number (IAGP)

increased red blood cell distribution width (IAGP)

lymphoid hyperplasia (IAGP)

myeloid hyperplasia (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:15489334	PMID:16141072	PMID:16141073	PMID:16602821	PMID:18959821
PMID:21267068	PMID:21873635	PMID:23375831	PMID:24937306	PMID:25391964	PMID:25558895	PMID:27775060	PMID:30240734

Genomics

Comparative Map Data

Tcim
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	24,927,188 - 24,928,962 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	24,927,196 - 24,929,000 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	24,437,172 - 24,438,946 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	24,437,180 - 24,438,984 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	25,548,088 - 25,549,418 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	25,903,161 - 25,904,491 (-)	NCBI		MGSCv36	mm8
Celera	8	25,921,731 - 25,923,061 (-)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI
cM Map	8	12.47	NCBI

TCIM
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	40,153,482 - 40,155,310 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	40,153,482 - 40,155,310 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	40,011,001 - 40,012,829 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	40,130,146 - 40,131,978 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	40,130,143 - 40,131,599	NCBI
Celera	8	38,962,805 - 38,964,636 (+)	NCBI		Celera
Cytogenetic Map	8	p11.21	NCBI
HuRef	8	38,544,322 - 38,546,161 (+)	NCBI		HuRef
CHM1_1	8	40,057,852 - 40,059,691 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	40,430,413 - 40,432,240 (+)	NCBI		T2T-CHM13v2.0

Tcim
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	74,298,344 - 74,299,637 (+)	NCBI		GRCr8
mRatBN7.2	16	67,595,762 - 67,597,055 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	67,593,410 - 67,597,581 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	72,872,855 - 72,874,148 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	76,278,586 - 76,279,879 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	71,527,785 - 71,529,078 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	72,388,842 - 72,390,135 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	72,401,887 - 72,403,179 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	16	72,388,880 - 72,389,200 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	72,046,896 - 72,048,224 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	16	65,493,820 - 65,495,113 (+)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

Tcim
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955536	2,786,482 - 2,786,799 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955536	2,786,384 - 2,786,988 (-)	NCBI	ChiLan1.0	ChiLan1.0

TCIM
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	58,608,882 - 58,610,232 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	34,325,847 - 34,327,196 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	39,347,441 - 39,348,795 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	36,854,973 - 36,856,432 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	36,855,045 - 36,855,365 (+)	Ensembl	panpan1.1		panPan2

TCIM
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	25,212,117 - 25,213,600 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	25,213,023 - 25,213,343 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	25,715,591 - 25,717,059 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	27,041,127 - 27,042,595 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	27,041,131 - 27,042,404 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	25,330,797 - 25,332,265 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	25,892,991 - 25,894,459 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	25,945,057 - 25,946,525 (-)	NCBI		UU_Cfam_GSD_1.0

Tcim
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	48,421,331 - 48,422,800 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936843	486,387 - 486,707 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936843	485,453 - 486,895 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TCIM
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	9,441,766 - 9,442,086 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	9,441,488 - 9,443,053 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TCIM
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	38,146,171 - 38,147,526 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	38,146,241 - 38,146,561 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	3,720,135 - 3,721,605 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tcim
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624780	3,515,018 - 3,515,335 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624780	3,514,082 - 3,515,411 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tcim
63 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	373
Count of miRNA genes:	260
Interacting mature miRNAs:	312
Transcripts:	ENSMUST00000052622
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558870	Eae36_m	experimental allergic encephalomyelitis susceptibility 36 (mouse)			Not determined		8	14773160	71498244	Mouse
1301298	Pgia4_m	proteoglycan induced arthritis 4 (mouse)			Not determined		8	16569373	50569697	Mouse
1300912	Daq19_m	directional asymmetry QTL 19 (mouse)			Not determined		8	15506572	49506729	Mouse
11532713	Sluc42_m	susceptibility to lung cancer 42 (mouse)					8	13447210	35321225	Mouse
4142199	Poats1_m	post-ovarectomy adrenal tumor susceptibility 1 (mouse)			Not determined			17082626	28849467	Mouse
1300603	Cd8ts2_m	CD8 T cell subset 2 (mouse)			Not determined		8	19455018	53455150	Mouse
4140978	Nilac5_m	nicotine induced locomotor activity 5 (mouse)			Not determined		8	1	31773288	Mouse
1301532	Scc8_m	colon tumor susceptibility 8 (mouse)			Not determined		8	7212499	35110107	Mouse
10412209	Cypr7_m	cytokine production 7 (mouse)			Not determined		8	8103201	42103372	Mouse
1301088	Alcw6_m	alcohol withdrawal 6 (mouse)			Not determined		8	15506572	49506729	Mouse
11533914	Mts5_m	mammary tumor susceptibility 5 (mouse)					8	1	30447432	Mouse
1300906	Ap8q_m	alcohol preference 8 QTL (mouse)			Not determined		8	7984189	41984342	Mouse
1301929	Eae24_m	susceptibility to experimental allergic encephalomyelitis 24 (mouse)			Not determined		8	8103201	42103372	Mouse
27226756	Femd2_m	femur midshaft diameter 2, 5 week (mouse)					8	4950000	35067154	Mouse
1301128	Sluc20_m	susceptibility to lung cancer 20 (mouse)			Not determined		8	8103201	42103372	Mouse
1301160	Eae14_m	susceptibility to experimental allergic encephalomyelitis 14 (mouse)			Not determined		8	19455018	53455150	Mouse
1301550	Fembrs2_m	femur breaking strength 2 (mouse)			Not determined		8	18321097	52321225	Mouse

Markers in Region

AW321058

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	24,437,274 - 24,437,423	UniSTS	GRCm38
MGSCv37	8	25,547,746 - 25,547,895	UniSTS	GRCm37
Celera	8	25,921,389 - 25,921,538	UniSTS
Cytogenetic Map	8	A2	UniSTS
Whitehead/MRC_RH	8	286.43	UniSTS

AW121743

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	8	24,437,675 - 24,437,821	UniSTS	GRCm38
MGSCv37	8	25,548,147 - 25,548,293	UniSTS	GRCm37
Celera	8	25,921,790 - 25,921,936	UniSTS
Cytogenetic Map	8	A2	UniSTS
Whitehead/MRC_RH	8	283.21	UniSTS

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_026931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC164300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK003102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK007441	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC016562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000052622 ⟹ ENSMUSP00000058631

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	8	24,927,196 - 24,929,000 (-)	Ensembl
GRCm38.p6 Ensembl	8	24,437,180 - 24,438,984 (-)	Ensembl

RefSeq Acc Id:

NM_026931 ⟹ NP_081207

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	8	24,927,188 - 24,928,962 (-)	NCBI
GRCm38	8	24,437,172 - 24,438,946 (-)	NCBI
MGSCv37	8	25,548,088 - 25,549,418 (-)	RGD
Celera	8	25,921,731 - 25,923,061 (-)	RGD
cM Map	8		ENTREZGENE

Sequence:

show sequence

AACAGACTCCCCTGGAAGTGCCCAAGCTGAGCCGTGGAAGACCCACATCGATGAAAGCCAAGCC
AAGCCATCAAGCCACCAGCATGTCCTCGTCTCTTCGAGTAAGCCCGTCCATCCACGGCTACCAC
TTCGACACAGCCGCTCGCAAGAAAGCTGTGGGCAACATCTTTGAGAACATAGACCAGGAGTCCC
TGCAGAGGCTCTTCAGGAACTCCGGAGACAAGAAGGCAGAGGAGCGGGCCAAGATCATTTTTGC
CATCGACCAAGATTTGGAGGAGAAAACTCGAGCCCTCATGGCCCTGAAGAAGAGGACAAAAGAC
AAGCTTCTTCAGTTTCTCAAACTGCGGAAATATTCCATCAAGGTACACTGAGCACAGCAGGCTG
GGCAAGAGCGTATCCACCAATGGACCTTTAAAGACCCAGTGAGCCTGCCAGCTCTGGCACGGGC
AGTGTCCCGCGAAAAGGCTTGAGAGCTTCCTCCGACAGGACCCCGAGGATGGAAAGGGACATAC
ATAACTCACCAGCTACACAGACTTGCAACTCATTGCAGCCCTGAGCTGTCCCACTGGGAGCCAA
GTGCCTTCAGCAGGCGTTGAGAACTCTCACAGCAGGAAAGGACATAGCCTGAGAGGATGGAGGC
ACTGACCAGAACACTGCGTTTGTGGGGACTGAGTGCACGCACCCAGGGCCGTTGGCAAGGCCCT
AAGACTAAACTCAAACCTAACTTGGTTTTTGTTCTTGTTGTTCGGTTTATTATTTTGTTTTCTT
TTTTCTTTTCTTCCTTTTTTCTTTTTTTAAATATTGAAGTGGGGAGGGAGGGAAGAGAAGGAAT
ATGAAGCATAAGTGGTTTACTGAAGTTTTGTGTGTTTTTTTTTTTAAATCTGAATGTTTAAAAA
TGTGGCTAAATCTCCGTGCTGTTTATTGGTCAAGATTTTTAGAGATCAGTAATTGTCTGCTTGC
ATTGAATACAATGGCTAAGACAGTGCACCCCCTGCTGTTAAAGTCAAAGAACTGGATGCCTGGC
CCAGCCCAGTAAAACCCCACAGCATGGGCTATGTTTCTACAGGATTTGTACACACTTCAAAATG
GTTTGCACAAAGCTGAAATAATGGGGCCCTTCATAAATCCGAAGGACTGTGAACAACTTTCGAA
TGTGCTTTTTAAAACTCTCTGACTAATGCTAAAATCTAATCTAATTAAATGTCCTCCAGACACT
GTAGTAAGCATTAGGAAATGAATATGGGGGATTTTAGAAGGATGCTGTGGGTTTTTTAAAATTA
TTTATTATGCATTGTAAGTGATACATAGCCCTAATAAATTATTATCAACTTAGCTTCTCTTTGC
TCTGTGGTGATCCGTCCCCAAGGGAAAAATATAGGATGGTAAATTTTGATCATTGTAAACTTTT
CTAGGGGTTGACTCTAAATCTTCCAGAGTAGCTTTATGCTGATTGCCAAACTTTTCCAAAACAA
GTTACAGCGCCAAGTGTCTACAGAGCCTTCTCCCCGCCCCCATTTTAAACTTCATGGCATAGAG
TTTCCCACAGAGTAATTTGGCAATATTGCTTTTATATATCCATAATCTATCTTCATTTTTCGTG
AAATTTCTCCTCTGTCACTACAGCAGATACATACCCATTTATTTCTTCCTAAACGGTATGTTTT
GAAGTTCGAGTGAATTATGATGAAGTTTCTGTGGGTCATTATAACATTAATATCTCTCTCCTTA
TTCCAGTATAATTTATAATAAAGCATTTCTAAAAAGGCATAAGCCAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_081207	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH16562	(Get FASTA)	NCBI Sequence Viewer
	BAB25041	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000058631
	ENSMUSP00000058631.5
GenBank Protein	Q9D915	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_081207 ⟸ NM_026931
- UniProtKB:	Q9D915 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKAKPSHQATSMSSSLRVSPSIHGYHFDTAARKKAVGNIFENIDQESLQRLFRNSGDKKAEERA KIIFAIDQDLEEKTRALMALKKRTKDKLLQFLKLRKYSIKVH hide sequence

Ensembl Acc Id:

ENSMUSP00000058631 ⟸ ENSMUST00000052622

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9D915-F1-model_v2	AlphaFold	Q9D915	1-106	view protein structure

Promoters

RGD ID:

8666723

Promoter ID:

EPDNEW_M11393

Type:

single initiation site

Name:

Tcim_1

Description:

Mus musculus transcriptional and immune response regulator ,mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	8	24,438,946 - 24,439,006	EPDNEW

RGD ID:

6842486

Promoter ID:

MM_KWN:53975

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

NM_026931

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	8	25,549,056 - 25,549,556 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1916318	AgrOrtholog
Ensembl Genes	ENSMUSG00000056313	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000052622	ENTREZGENE
	ENSMUST00000052622.6	UniProtKB/Swiss-Prot
InterPro	Avpi1/C8orf4_dom	UniProtKB/Swiss-Prot
	Tcim	UniProtKB/Swiss-Prot
KEGG Report	mmu:69068	UniProtKB/Swiss-Prot
MGD	MGI:1916318	ENTREZGENE
NCBI Gene	69068	ENTREZGENE
PANTHER	PTHR32358	UniProtKB/Swiss-Prot
	TRANSCRIPTIONAL AND IMMUNE RESPONSE REGULATOR	UniProtKB/Swiss-Prot
Pfam	TC1	UniProtKB/Swiss-Prot
PhenoGen	Tcim	PhenoGen
UniProt	Q9D915	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-09-26	Tcim	transcriptional and immune response regulator	1810011O10Rik	RIKEN cDNA 1810011O10 gene	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Mammalian Phenotype