Brd1 (bromodomain containing 1) - Rat Genome Database

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Gene: Brd1 (bromodomain containing 1) Mus musculus
Analyze
Symbol: Brd1
Name: bromodomain containing 1
RGD ID: 1622985
MGI Page MGI
Description: Enables histone reader activity. Involved in positive regulation of erythrocyte differentiation. Part of histone H3-K14 acetyltransferase complex. Is expressed in brain; genitourinary system; and olfactory epithelium. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Orthologous to human BRD1 (bromodomain containing 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110059H06Rik; AI316859; bromodomain and PHD finger-containing protein 2; bromodomain-containing protein 1; KIAA4191; MGC164733; mKIAA4191; RIKEN cDNA 1110059H06 gene
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391588,571,237 - 88,618,508 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1588,571,237 - 88,618,436 (-)EnsemblGRCm39 Ensembl
GRCm381588,687,034 - 88,734,228 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1588,687,034 - 88,734,233 (-)EnsemblGRCm38mm10GRCm38
MGSCv371588,517,465 - 88,564,649 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361588,526,617 - 88,561,996 (-)NCBIMGSCv36mm8
Celera1590,812,128 - 90,859,347 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electroconvulsive seizures regulates the Brd1 gene in the frontal cortex and hippocampus of the adult rat. Fryland T, etal., Neurosci Lett. 2012 May 10;516(1):110-3.
2. Association study of bromodomain-containing 1 gene with schizophrenia in Japanese population. Kushima I, etal., Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 5;153B(3):786-91. doi: 10.1002/ajmg.b.31048.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The bromodomain: From epigenome reader to druggable target. Sanchez R, etal., Biochim Biophys Acta. 2014 Aug;1839(8):676-685. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28.
7. Evidence implicating BRD1 with brain development and susceptibility to both schizophrenia and bipolar affective disorder. Severinsen JE, etal., Mol Psychiatry. 2006 Dec;11(12):1126-38. Epub 2006 Aug 22.
Additional References at PubMed
PMID:10349636   PMID:10512203   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273  
PMID:15618518   PMID:15840001   PMID:16141072   PMID:16141073   PMID:16387653   PMID:17967808   PMID:18287559   PMID:18799693   PMID:21267068   PMID:21753189   PMID:21873635   PMID:24025402  
PMID:25519988   PMID:25773539   PMID:26208977   PMID:26677226   PMID:27256846   PMID:27837920   PMID:28106071   PMID:28341151   PMID:28378742   PMID:30405140   PMID:30590179   PMID:32681022  
PMID:34056693  


Genomics

Comparative Map Data
Brd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391588,571,237 - 88,618,508 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1588,571,237 - 88,618,436 (-)EnsemblGRCm39 Ensembl
GRCm381588,687,034 - 88,734,228 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1588,687,034 - 88,734,233 (-)EnsemblGRCm38mm10GRCm38
MGSCv371588,517,465 - 88,564,649 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361588,526,617 - 88,561,996 (-)NCBIMGSCv36mm8
Celera1590,812,128 - 90,859,347 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.17NCBI
BRD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382249,773,278 - 49,827,873 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2249,773,283 - 49,827,873 (-)EnsemblGRCh38hg38GRCh38
GRCh372250,166,926 - 50,221,521 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362248,552,941 - 48,604,456 (-)NCBINCBI36Build 36hg18NCBI36
Build 342248,487,798 - 48,539,313NCBI
Celera2234,088,639 - 34,139,967 (-)NCBICelera
Cytogenetic Map22q13.33NCBI
HuRef2233,113,327 - 33,164,844 (-)NCBIHuRef
CHM1_12250,125,661 - 50,177,036 (-)NCBICHM1_1
T2T-CHM13v2.02250,277,574 - 50,332,170 (-)NCBIT2T-CHM13v2.0
Brd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87121,653,859 - 121,701,700 (-)NCBIGRCr8
mRatBN7.27119,774,187 - 119,822,032 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7119,774,188 - 119,822,031 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7121,525,863 - 121,573,444 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07123,752,248 - 123,799,625 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07123,715,287 - 123,762,868 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07129,676,119 - 129,724,303 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7129,676,120 - 129,724,303 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07129,366,020 - 129,413,531 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47126,987,011 - 127,035,473 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17127,021,242 - 127,065,922 (-)NCBI
Celera7116,251,952 - 116,296,145 (-)NCBICelera
Cytogenetic Map7q34NCBI
Brd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541332,935,827 - 32,973,804 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541332,935,827 - 32,973,820 (-)NCBIChiLan1.0ChiLan1.0
BRD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22359,672,101 - 59,753,163 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12262,356,539 - 62,438,053 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02229,993,902 - 30,048,349 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12248,998,037 - 49,048,101 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2248,998,037 - 49,048,101 (-)Ensemblpanpan1.1panPan2
BRD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11017,361,043 - 17,396,725 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1017,361,117 - 17,395,928 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1017,340,501 - 17,376,828 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01018,090,452 - 18,126,790 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1018,090,531 - 18,126,770 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11017,813,377 - 17,849,653 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01018,136,398 - 18,172,666 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01018,268,415 - 18,304,716 (+)NCBIUU_Cfam_GSD_1.0
Brd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945909,698 - 976,387 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936629909,680 - 958,896 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936629909,716 - 958,620 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5770,654 - 808,006 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15774,307 - 808,016 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25111,001,215 - 111,004,246 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BRD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11932,261,796 - 32,323,528 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1932,261,833 - 32,320,706 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604593,072,511 - 93,124,341 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624752811,451 - 854,039 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624752811,457 - 853,702 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Brd1
1702 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1311
Count of miRNA genes:716
Interacting mature miRNAs:898
Transcripts:ENSMUST00000088911, ENSMUST00000109380, ENSMUST00000109381, ENSMUST00000139515, ENSMUST00000150004, ENSMUST00000156155
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1558845Alprf_malcohol preference (mouse)Not determined158734927190274568Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
12738413Lfibq10_mliver fibrosis QTL 10 (mouse)158784208589927286Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse

Markers in Region
RH136139  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381588,687,578 - 88,687,773UniSTSGRCm38
MGSCv371588,518,008 - 88,518,203UniSTSGRCm37
Celera1590,812,671 - 90,812,866UniSTS
Cytogenetic Map15E3UniSTS
D15Ertd55e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381588,710,924 - 88,711,156UniSTSGRCm38
MGSCv371588,541,354 - 88,541,586UniSTSGRCm37
Celera1590,836,087 - 90,836,319UniSTS
Cytogenetic Map15E3UniSTS
cM Map1549.9UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030248510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_384007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_384008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB610711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC152356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000088911
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1588,583,054 - 88,618,433 (-)Ensembl
GRCm38.p6 Ensembl1588,698,851 - 88,734,230 (-)Ensembl
Ensembl Acc Id: ENSMUST00000109380   ⟹   ENSMUSP00000105006
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1588,572,499 - 88,614,974 (-)Ensembl
GRCm38.p6 Ensembl1588,688,296 - 88,730,771 (-)Ensembl
Ensembl Acc Id: ENSMUST00000109381   ⟹   ENSMUSP00000105007
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1588,571,237 - 88,618,436 (-)Ensembl
GRCm38.p6 Ensembl1588,687,034 - 88,734,233 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139515
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1588,597,636 - 88,601,243 (-)Ensembl
GRCm38.p6 Ensembl1588,713,433 - 88,717,040 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150004
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1588,580,249 - 88,585,067 (-)Ensembl
GRCm38.p6 Ensembl1588,696,046 - 88,700,864 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156155
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1588,597,103 - 88,603,358 (-)Ensembl
GRCm38.p6 Ensembl1588,712,900 - 88,719,155 (-)Ensembl
RefSeq Acc Id: NM_001033274   ⟹   NP_001028446
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,238 - 88,618,422 (-)NCBI
GRCm381588,687,035 - 88,734,219 (-)NCBI
MGSCv371588,517,465 - 88,564,649 (-)RGD
Celera1590,812,128 - 90,859,347 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006520834   ⟹   XP_006520897
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
GRCm381588,687,034 - 88,734,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006520835   ⟹   XP_006520898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
GRCm381588,687,034 - 88,734,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006520836   ⟹   XP_006520899
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
GRCm381588,687,034 - 88,734,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248510   ⟹   XP_030104370
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
GRCm381588,687,034 - 88,734,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159368   ⟹   XP_036015261
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004938826
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004938827
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004938828
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
Sequence:
RefSeq Acc Id: XR_384007
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
GRCm381588,687,034 - 88,734,228 (-)NCBI
Sequence:
RefSeq Acc Id: XR_384008
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391588,571,237 - 88,618,508 (-)NCBI
GRCm381588,692,880 - 88,734,228 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001028446   ⟸   NM_001033274
- UniProtKB: A7MCW6 (UniProtKB/TrEMBL),   E9PZ26 (UniProtKB/TrEMBL),   Q3UE68 (UniProtKB/TrEMBL),   Q571F6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006520897   ⟸   XM_006520834
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006520899   ⟸   XM_006520836
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006520898   ⟸   XM_006520835
- Peptide Label: isoform X3
- UniProtKB: Q8BU83 (UniProtKB/Swiss-Prot),   Q571F6 (UniProtKB/Swiss-Prot),   G5E8P1 (UniProtKB/Swiss-Prot),   E9PZ26 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030104370   ⟸   XM_030248510
- Peptide Label: isoform X4
Ensembl Acc Id: ENSMUSP00000105006   ⟸   ENSMUST00000109380
Ensembl Acc Id: ENSMUSP00000105007   ⟸   ENSMUST00000109381
RefSeq Acc Id: XP_036015261   ⟸   XM_036159368
- Peptide Label: isoform X1
Protein Domains
Bromo   Enhancer of polycomb-like N-terminal   PHD-type   PWWP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G5E8P1-F1-model_v2 AlphaFold G5E8P1 1-1058 view protein structure

Promoters
RGD ID:6826217
Promoter ID:MM_KWN:19362
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung
Transcripts:UC007XEI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361588,537,841 - 88,538,627 (-)MPROMDB
RGD ID:6826219
Promoter ID:MM_KWN:19363
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:UC007XEJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361588,542,926 - 88,544,077 (-)MPROMDB
RGD ID:6825819
Promoter ID:MM_KWN:19364
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Kidney
Transcripts:OTTMUST00000041951
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361588,547,596 - 88,548,096 (-)MPROMDB
RGD ID:6825820
Promoter ID:MM_KWN:19365
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000041949
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361588,549,201 - 88,549,701 (-)MPROMDB
RGD ID:6826236
Promoter ID:MM_KWN:19366
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:UC007XEK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361588,560,146 - 88,562,022 (-)MPROMDB
RGD ID:6825821
Promoter ID:MM_KWN:19368
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000088911,   ENSMUST00000109381
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361588,564,341 - 88,564,987 (-)MPROMDB
RGD ID:8684672
Promoter ID:EPDNEW_M20367
Type:initiation region
Name:Brd1_1
Description:Mus musculus bromodomain containing 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381588,734,233 - 88,734,293EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1924161 AgrOrtholog
Ensembl Genes ENSMUSG00000022387 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000109380 ENTREZGENE
  ENSMUST00000109380.8 UniProtKB/Swiss-Prot
  ENSMUST00000109381 ENTREZGENE
  ENSMUST00000109381.9 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.920.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.30.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Bromodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRPF2_ePHD UniProtKB/Swiss-Prot
  BRPF2_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Enhancer_polycomb-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_Mod_Regulator UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:223770 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1924161 ENTREZGENE
NCBI Gene Brd1 ENTREZGENE
PANTHER BROMODOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHD FINGER PROTEINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-HC5HC2H_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Brd1 PhenoGen
PRINTS BROMODOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BROMO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PWWP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tudor/PWWP/MBT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A1L3T8_MOUSE UniProtKB/TrEMBL
  A7MCW6 ENTREZGENE, UniProtKB/TrEMBL
  BRD1_MOUSE UniProtKB/Swiss-Prot
  E9PZ26 ENTREZGENE
  G5E8P1 ENTREZGENE
  Q3UE68 ENTREZGENE, UniProtKB/TrEMBL
  Q571F6 ENTREZGENE
  Q6PG78_MOUSE UniProtKB/TrEMBL
  Q80UP2_MOUSE UniProtKB/TrEMBL
  Q8BU83 ENTREZGENE
UniProt Secondary E9PZ26 UniProtKB/Swiss-Prot
  Q571F6 UniProtKB/Swiss-Prot
  Q8BU83 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-09-25 Brd1  bromodomain containing 1  Brd1  RIKEN cDNA 1110059H06 gene  Symbol and/or name change 5135510 APPROVED
2024-08-21 Brd1  RIKEN cDNA 1110059H06 gene  Brd1  bromodomain containing 1  Symbol and/or name change 5135510 APPROVED