Exosc1 (exosome component 1) - Rat Genome Database

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Gene: Exosc1 (exosome component 1) Mus musculus
Analyze
Symbol: Exosc1
Name: exosome component 1
RGD ID: 1622319
MGI Page MGI
Description: Predicted to enable RNA binding activity. Predicted to be involved in RNA catabolic process and RNA processing. Predicted to act upstream of or within rRNA processing. Predicted to be located in cytosol and nucleolus. Predicted to be part of nuclear exosome (RNase complex). Predicted to be active in cytoplasm. Is expressed in several structures, including cerebral cortex; early conceptus; gonad; liver; and submandibular gland primordium. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1F. Orthologous to human EXOSC1 (exosome component 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610035C18Rik; 2610104C07Rik; 2610312F07Rik; 3'-5' exoribonuclease CSL4 homolog; AI447561; exosome complex component CSL4; exosome complex component CSL4 short isoform
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm12007   Gm17946  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391941,911,417 - 41,921,836 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1941,910,731 - 41,921,862 (-)EnsemblGRCm39 Ensembl
GRCm381941,922,978 - 41,933,423 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1941,922,292 - 41,933,423 (-)EnsemblGRCm38mm10GRCm38
MGSCv371941,997,470 - 42,007,804 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361941,977,030 - 41,986,605 (-)NCBIMGSCv36mm8
Celera1942,724,141 - 42,734,563 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1935.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15489334  
PMID:16141072   PMID:16141073   PMID:18799693   PMID:20531386   PMID:21267068   PMID:21791617   PMID:21873635   PMID:22045912   PMID:22421546   PMID:22922362   PMID:26496610   PMID:27480124  
PMID:27538750   PMID:30196744   PMID:33462115   PMID:34159897   PMID:37940010   PMID:38355793  


Genomics

Comparative Map Data
Exosc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391941,911,417 - 41,921,836 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1941,910,731 - 41,921,862 (-)EnsemblGRCm39 Ensembl
GRCm381941,922,978 - 41,933,423 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1941,922,292 - 41,933,423 (-)EnsemblGRCm38mm10GRCm38
MGSCv371941,997,470 - 42,007,804 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361941,977,030 - 41,986,605 (-)NCBIMGSCv36mm8
Celera1942,724,141 - 42,734,563 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1935.46NCBI
EXOSC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381097,435,909 - 97,446,006 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1097,435,909 - 97,446,017 (-)EnsemblGRCh38hg38GRCh38
GRCh371099,195,666 - 99,205,763 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361099,185,656 - 99,195,758 (-)NCBINCBI36Build 36hg18NCBI36
Build 341099,181,068 - 99,195,741NCBI
Celera1092,903,619 - 92,943,824 (-)NCBICelera
Cytogenetic Map10q24.1NCBI
HuRef1092,821,320 - 92,831,424 (-)NCBIHuRef
CHM1_11099,477,406 - 99,487,508 (-)NCBICHM1_1
T2T-CHM13v2.01098,316,090 - 98,326,186 (-)NCBIT2T-CHM13v2.0
Exosc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81250,684,746 - 250,694,748 (-)NCBIGRCr8
mRatBN7.21240,734,777 - 240,745,431 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1240,734,773 - 240,745,438 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1248,880,748 - 248,890,754 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01255,577,896 - 255,587,900 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01248,230,907 - 248,240,911 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01261,169,798 - 261,179,865 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1261,170,229 - 261,179,790 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01268,621,714 - 268,632,337 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1236,570,459 - 236,580,516 (-)NCBICelera
Cytogenetic Map1q54NCBI
Exosc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555073,576,555 - 3,583,183 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555073,576,555 - 3,583,183 (-)NCBIChiLan1.0ChiLan1.0
EXOSC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28109,350,417 - 109,360,407 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110109,355,835 - 109,365,726 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01094,058,794 - 94,068,776 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11097,552,667 - 97,562,253 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1097,552,874 - 97,562,233 (-)Ensemblpanpan1.1panPan2
EXOSC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12810,729,186 - 10,738,978 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2810,731,243 - 10,738,900 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2810,911,886 - 10,921,678 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02811,051,515 - 11,061,308 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2811,050,820 - 11,061,552 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12810,712,577 - 10,722,369 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02810,773,099 - 10,782,899 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02810,913,284 - 10,923,076 (-)NCBIUU_Cfam_GSD_1.0
Exosc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721336,191,538 - 36,199,489 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366362,230,737 - 2,238,135 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366362,230,712 - 2,237,401 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOSC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14108,830,906 - 108,842,780 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114108,834,609 - 108,842,827 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214118,340,140 - 118,346,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EXOSC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1990,603,371 - 90,615,934 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl990,602,667 - 90,615,840 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604851,503,258 - 51,513,397 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exosc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247379,101,483 - 9,107,336 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247379,099,752 - 9,107,393 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Exosc1
293 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:612
Count of miRNA genes:248
Interacting mature miRNAs:280
Transcripts:ENSMUST00000075280, ENSMUST00000112123
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192738559461385705Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192023431454234461Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193837605061420004Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193675259761420004Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193918406461420004Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191591260749912719Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192231332653911504Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191591260749912719Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193395195261420004Mouse
14928311Manh85_mmandible shape 85 (mouse)191191478945914789Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192542691759427005Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193014122461420004Mouse
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193959606661420004Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3459678661420004Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192137870555378928Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193014123161420004Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191829516252295381Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191492301648923138Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192498843958988439Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193089788061420004Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2814034861420004Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193788298261420004Mouse
13504736Ifvrq6_minfluenza virus resistance QTL 6 (mouse)193690291044913949Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193014123161420004Mouse
1301479Sluc1_msusceptibility to lung cancer 1 (mouse)Not determined193601694446761521Mouse
1302123Tlsr8_mthymic lymphoma suppressor region 8 (mouse)Not determined192513600242388916Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192023431454234461Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191829516252295381Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193299215861420004Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse

Markers in Region
AI447561  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381941,923,048 - 41,923,177UniSTSGRCm38
MGSCv371941,997,538 - 41,997,667UniSTSGRCm37
Celera1942,724,209 - 42,724,338UniSTS
Cytogenetic Map19D1UniSTS
Whitehead/MRC_RH19421.62UniSTS
MARC_23511-23512:1027359213:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381941,923,994 - 41,924,781UniSTSGRCm38
MGSCv371941,998,484 - 41,999,271UniSTSGRCm37
Celera1942,725,155 - 42,725,943UniSTS
Cytogenetic Map19D1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001164561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001320233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_025644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030251027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036161652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC140193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK006018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK006333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY361617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX371790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000075280   ⟹   ENSMUSP00000074756
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1941,912,005 - 41,921,735 (-)Ensembl
GRCm38.p6 Ensembl1941,923,566 - 41,933,296 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112123   ⟹   ENSMUSP00000107751
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1941,910,731 - 41,921,862 (-)Ensembl
GRCm38.p6 Ensembl1941,922,292 - 41,933,423 (-)Ensembl
Ensembl Acc Id: ENSMUST00000237177
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1941,920,147 - 41,921,737 (-)Ensembl
GRCm38.p6 Ensembl1941,931,708 - 41,933,298 (-)Ensembl
Ensembl Acc Id: ENSMUST00000238034
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1941,919,586 - 41,921,687 (-)Ensembl
GRCm38.p6 Ensembl1941,931,147 - 41,933,248 (-)Ensembl
RefSeq Acc Id: NM_001164561   ⟹   NP_001158033
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,419 - 41,921,753 (-)NCBI
GRCm381941,922,980 - 41,933,314 (-)NCBI
MGSCv371941,997,470 - 42,007,804 (-)RGD
Celera1942,724,141 - 42,734,563 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001320231   ⟹   NP_001307160
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,419 - 41,921,753 (-)NCBI
GRCm381941,922,980 - 41,933,314 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320232   ⟹   NP_001307161
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,419 - 41,921,753 (-)NCBI
GRCm381941,922,980 - 41,933,314 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001320233   ⟹   NP_001307162
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,419 - 41,921,753 (-)NCBI
GRCm381941,922,980 - 41,933,314 (-)NCBI
Sequence:
RefSeq Acc Id: NM_025644   ⟹   NP_079920
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,419 - 41,921,753 (-)NCBI
GRCm381941,922,980 - 41,933,314 (-)NCBI
MGSCv371941,997,470 - 42,007,804 (-)RGD
Celera1942,724,141 - 42,734,563 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011247312   ⟹   XP_011245614
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,418 - 41,921,832 (-)NCBI
GRCm381941,922,978 - 41,933,419 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247313   ⟹   XP_011245615
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,418 - 41,921,836 (-)NCBI
GRCm381941,922,978 - 41,933,423 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017318274   ⟹   XP_017173763
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,417 - 41,916,509 (-)NCBI
GRCm381941,922,978 - 41,928,070 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030251027   ⟹   XP_030106887
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,418 - 41,921,818 (-)NCBI
GRCm381941,922,978 - 41,933,415 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036161652   ⟹   XP_036017545
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391941,911,418 - 41,921,835 (-)NCBI
Sequence:
RefSeq Acc Id: NP_079920   ⟸   NM_025644
- Peptide Label: isoform 1
- UniProtKB: Q9DCB9 (UniProtKB/Swiss-Prot),   Q9DAA6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001158033   ⟸   NM_001164561
- Peptide Label: isoform 2
- UniProtKB: Q9DAA6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011245615   ⟸   XM_011247313
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011245614   ⟸   XM_011247312
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017173763   ⟸   XM_017318274
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: NP_001307162   ⟸   NM_001320233
- Peptide Label: isoform 5
- UniProtKB: Q9DAA6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001307160   ⟸   NM_001320231
- Peptide Label: isoform 3
- UniProtKB: Q9DAA6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001307161   ⟸   NM_001320232
- Peptide Label: isoform 4
- UniProtKB: Q9DAA6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030106887   ⟸   XM_030251027
- Peptide Label: isoform X4
Ensembl Acc Id: ENSMUSP00000107751   ⟸   ENSMUST00000112123
Ensembl Acc Id: ENSMUSP00000074756   ⟸   ENSMUST00000075280
RefSeq Acc Id: XP_036017545   ⟸   XM_036161652
- Peptide Label: isoform X3
Protein Domains
Exosome complex component N-terminal   S1 motif

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9DAA6-F1-model_v2 AlphaFold Q9DAA6 1-195 view protein structure

Promoters
RGD ID:13679490
Promoter ID:EPDNEW_M23894
Type:multiple initiation site
Name:Exosc1_1
Description:Mus musculus exosome component 1 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381941,933,301 - 41,933,361EPDNEW
RGD ID:6830019
Promoter ID:MM_KWN:27072
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001164561,   NM_023740,   NM_025644,   UC008HMO.1,   UC008HMP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361942,007,721 - 42,008,517 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913833 AgrOrtholog
Ensembl Genes ENSMUSG00000034321 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000075280 ENTREZGENE
  ENSMUST00000075280.12 UniProtKB/Swiss-Prot
  ENSMUST00000112123 ENTREZGENE
  ENSMUST00000112123.4 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.50.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Csl4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Exosome_cplx_CSL4 UniProtKB/Swiss-Prot
  Exosome_cplx_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S1_domain UniProtKB/Swiss-Prot
KEGG Report mmu:66583 UniProtKB/Swiss-Prot
MGD MGI:1913833 ENTREZGENE
NCBI Gene 66583 ENTREZGENE
PANTHER EXOSOME COMPLEX COMPONENT CSL4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12686 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ECR1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EXOSC1 UniProtKB/Swiss-Prot
PhenoGen Exosc1 PhenoGen
SMART SM00316 UniProtKB/Swiss-Prot
Superfamily-SCOP Ribosomal L27 protein-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50249 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1S7D812_MOUSE UniProtKB/TrEMBL
  EXOS1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9DCB9 ENTREZGENE
UniProt Secondary Q9DCB9 UniProtKB/Swiss-Prot