Frem2 (Fras1 related extracellular matrix protein 2) - Rat Genome Database

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Gene: Frem2 (Fras1 related extracellular matrix protein 2) Mus musculus
Analyze
Symbol: Frem2
Name: Fras1 related extracellular matrix protein 2
RGD ID: 1622040
MGI Page MGI
Description: Predicted to enable metal ion binding activity. Involved in eye development. Acts upstream of or within several processes, including embryonic digit morphogenesis; inner ear development; and kidney development. Located in basement membrane. Is expressed in several structures, including alimentary system; central nervous system; integumental system; intraembryonic coelom; and sensory organ. Used to study Fraser syndrome and isolated cryptophthalmia. Human ortholog(s) of this gene implicated in Fraser syndrome 2 and isolated cryptophthalmia. Orthologous to human FREM2 (FRAS1 related extracellular matrix 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6030440P17Rik; 8430406N05Rik; b2b1562C; b2b1562Clo; ECM3 homolog; embryonic blastocoelar extracellular matrix protein-like; FRAS1-related extracellular matrix protein 2; Gm409; my; n; ne; NV domain containing protein NV1; NV domain-containing protein 1; nv1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39353,421,359 - 53,566,014 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl353,421,359 - 53,564,776 (-)EnsemblGRCm39 Ensembl
GRCm38353,513,938 - 53,658,593 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl353,513,938 - 53,657,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv37353,317,860 - 53,461,277 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36353,601,867 - 53,745,013 (-)NCBIMGSCv36mm8
Celera353,238,829 - 53,381,524 (-)NCBICelera
Cytogenetic Map3CNCBI
cM Map325.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior eye segment morphology  (IAGP)
abnormal coat/hair pigmentation  (IAGP)
abnormal cornea morphology  (IAGP)
abnormal craniofacial development  (IEA)
abnormal digit morphology  (IAGP)
abnormal ear shape  (IEA)
abnormal embryo development  (IAGP)
abnormal eye development  (IAGP)
abnormal eye morphology  (IAGP)
abnormal eyelid morphology  (IEA)
abnormal facial morphology  (IEA)
abnormal head morphology  (IAGP)
abnormal heart valve morphology  (IAGP)
abnormal lens morphology  (IAGP)
abnormal limb morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal skin morphology  (IAGP)
absent ciliary body  (IAGP)
absent kidney  (IAGP)
absent outer ear  (IAGP)
acoria  (IAGP)
acrania  (IAGP)
anophthalmia  (IAGP)
atrial septal defect  (IAGP)
bleb  (IAGP)
clubfoot  (IAGP)
corneal vascularization  (IAGP)
cryptophthalmos  (IAGP)
decreased birth weight  (IAGP)
decreased litter size  (IEA)
diaphragmatic hernia  (IEA)
eye bleb  (IEA)
fetal bleb  (IAGP)
fused phalanges  (IEA)
hemorrhage  (IAGP)
hydrocephaly  (IEA)
increased total retina thickness  (IAGP)
iris hypoplasia  (IAGP)
iris synechia  (IAGP)
irregular coat pigmentation  (IEA)
kidney cortex cyst  (IAGP)
meroanencephaly  (IAGP)
microphthalmia  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
oligodactyly  (IAGP)
open neural tube  (IAGP)
perinatal lethality, incomplete penetrance  (IEA)
polydactyly  (IEA)
preaxial polydactyly  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
right aortic arch  (IEA)
short face  (IEA)
short snout  (IEA)
single kidney  (IAGP)
small ears  (IAGP)
sparse hair  (IAGP)
syndactyly  (IAGP)
variable body spotting  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Fused pulmonary lobes is a rat model of human Fraser syndrome. Kiyozumi D, etal., Biochem Biophys Res Commun. 2011 Jul 29;411(2):440-4. doi: 10.1016/j.bbrc.2011.06.174. Epub 2011 Jul 2.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:405279   PMID:820740   PMID:1515706   PMID:5088022   PMID:6160178   PMID:8055142   PMID:8889548   PMID:9302549   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851  
PMID:12466851   PMID:12477932   PMID:12520002   PMID:14730302   PMID:15489334   PMID:15838507   PMID:15878328   PMID:16087869   PMID:16141072   PMID:16141073   PMID:16880404   PMID:17246673  
PMID:17251066   PMID:17462874   PMID:17596926   PMID:18563433   PMID:18787044   PMID:20843830   PMID:21267068   PMID:21289216   PMID:21693562   PMID:21795542   PMID:21873635   PMID:21993971  
PMID:22159717   PMID:22613833   PMID:23064016   PMID:23221805   PMID:23536828   PMID:24101214   PMID:24952961   PMID:25807483   PMID:25917818   PMID:26234751   PMID:26930384   PMID:27002738  
PMID:27856617   PMID:28705898   PMID:29618029   PMID:30567998   PMID:30802441   PMID:33490088   PMID:33875569   PMID:36335435   PMID:36495293  


Genomics

Comparative Map Data
Frem2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39353,421,359 - 53,566,014 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl353,421,359 - 53,564,776 (-)EnsemblGRCm39 Ensembl
GRCm38353,513,938 - 53,658,593 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl353,513,938 - 53,657,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv37353,317,860 - 53,461,277 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36353,601,867 - 53,745,013 (-)NCBIMGSCv36mm8
Celera353,238,829 - 53,381,524 (-)NCBICelera
Cytogenetic Map3CNCBI
cM Map325.24NCBI
FREM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381338,687,077 - 38,887,131 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1338,687,077 - 38,887,131 (+)EnsemblGRCh38hg38GRCh38
GRCh371339,261,214 - 39,461,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361338,159,173 - 38,359,268 (+)NCBINCBI36Build 36hg18NCBI36
Build 341338,255,292 - 38,358,072NCBI
Celera1320,314,868 - 20,515,290 (+)NCBICelera
Cytogenetic Map13q13.3NCBI
HuRef1320,059,603 - 20,259,887 (+)NCBIHuRef
CHM1_11339,228,938 - 39,428,968 (+)NCBICHM1_1
T2T-CHM13v2.01337,903,789 - 38,103,862 (+)NCBIT2T-CHM13v2.0
Frem2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22137,602,784 - 137,740,785 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2137,602,784 - 137,740,785 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2144,186,132 - 144,324,110 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02142,298,198 - 142,436,165 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02136,929,969 - 137,067,935 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02142,747,501 - 142,885,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2142,747,501 - 142,885,604 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02162,430,795 - 162,568,910 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42142,464,169 - 142,604,059 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2132,100,362 - 132,238,927 (-)NCBICelera
Cytogenetic Map2q26NCBI
Frem2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554317,364,937 - 7,541,648 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554317,364,937 - 7,541,419 (-)NCBIChiLan1.0ChiLan1.0
FREM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11329,319,867 - 29,523,385 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01319,900,324 - 20,103,303 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11338,490,750 - 38,692,200 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1338,490,750 - 38,687,048 (+)Ensemblpanpan1.1panPan2
FREM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1252,097,264 - 2,264,049 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl252,102,849 - 2,264,456 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha252,193,436 - 2,359,496 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0252,194,254 - 2,360,131 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl252,198,985 - 2,359,379 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1252,095,553 - 2,261,726 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0252,089,594 - 2,255,805 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0252,159,315 - 2,325,419 (-)NCBIUU_Cfam_GSD_1.0
Frem2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945163,183,741 - 163,353,464 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365656,671,737 - 6,837,514 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365656,671,578 - 6,837,514 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FREM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1113,959,666 - 14,113,230 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11113,775,267 - 14,116,377 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FREM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1317,121,063 - 17,310,149 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl317,129,126 - 17,300,363 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605726,957,763 - 27,140,436 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frem2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249201,683,351 - 1,904,557 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249201,683,342 - 1,908,602 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Frem2
6334 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1102
Count of miRNA genes:531
Interacting mature miRNAs:681
Transcripts:ENSMUST00000091137
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32017486254180103Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1300961Bh4p_mbar holding four paws (mouse)Not determined33183785465837997Mouse
12910778Pwgrq13_mpost-weaning growth rate QTL 13 (mouse)33263576058017363Mouse
12910781Pwgrq12_mpost-weaning growth rate QTL 12 (mouse)33263576058017363Mouse
10412073Ssen2_msuseptibility to Sendai virus 2 (mouse)Not determined33353546567535615Mouse
9587784Afw13_mabdominal fat weight QTL 13 (mouse)Not determined33375204567752228Mouse
10043882Bwtq13_mbody weight QTL 13 (mouse)Not determined33375204567752228Mouse
15039332Nmrs6_mNAFLD-associated magnetic resonance shift 6 (mouse)33417074168170741Mouse
15039336Nmrs2_mNAFLD-associated magnetic resonance shift 2 (mouse)33457610368576103Mouse
18337272Bmd46_mbone mineral density 46, males (mouse)33540742169407421Mouse
14746977Manh53_mmandible shape 53 (mouse)33592528069925280Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
1300587Aod2_mautoimmune ovarian dysgenesis 2 (mouse)Not determined33717974268716946Mouse
11041901Lmr11b_mleishmaniasis resistance 11b (mouse)33970410273704231Mouse
11039513Ltpr3a_mLeishmania tropica response 3a (mouse)33970410273704231Mouse
1301585Cd4ts1_mCD4 T cell subset 1 (mouse)Not determined33970410273704231Mouse
10755516Amzn1_manatomical modifier of Zfp423 1 (mouse)33970410273704231Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884389Skwq10_mskull length QTL 10, 16 week (mouse)34395443565307421Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4935758183357581Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34949500583495118Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34949500583495118Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35262550986625745Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35262550986625745Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35262550986625745Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35292318386923183Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_172862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB160988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB236662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC121885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC138112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ833643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE864729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF742372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN530725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN534900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN536459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000091137   ⟹   ENSMUSP00000088670
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl353,421,359 - 53,564,776 (-)Ensembl
GRCm38.p6 Ensembl353,513,938 - 53,657,355 (-)Ensembl
RefSeq Acc Id: ENSMUST00000197519
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl353,423,273 - 53,451,689 (-)Ensembl
GRCm38.p6 Ensembl353,515,852 - 53,544,268 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199323
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl353,555,013 - 53,559,651 (-)Ensembl
GRCm38.p6 Ensembl353,647,592 - 53,652,230 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl353,423,377 - 53,430,441 (-)Ensembl
GRCm38.p6 Ensembl353,515,956 - 53,523,020 (-)Ensembl
RefSeq Acc Id: NM_172862   ⟹   NP_766450
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39353,421,359 - 53,564,776 (-)NCBI
GRCm38353,513,938 - 53,657,355 (-)NCBI
MGSCv37353,317,860 - 53,461,277 (-)RGD
Celera353,238,829 - 53,381,524 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501461   ⟹   XP_006501524
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39353,537,188 - 53,566,014 (-)NCBI
GRCm38353,629,767 - 53,658,593 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006501462   ⟹   XP_006501525
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39353,520,014 - 53,566,014 (-)NCBI
GRCm38353,612,587 - 53,658,593 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_766450   ⟸   NM_172862
- Peptide Label: precursor
- UniProtKB: Q8C4G5 (UniProtKB/Swiss-Prot),   Q811G9 (UniProtKB/Swiss-Prot),   Q5H8C0 (UniProtKB/Swiss-Prot),   Q4W2Q5 (UniProtKB/Swiss-Prot),   Q8CD46 (UniProtKB/Swiss-Prot),   Q6NVD0 (UniProtKB/Swiss-Prot),   Q1XGY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006501525   ⟸   XM_006501462
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006501524   ⟸   XM_006501461
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000088670   ⟸   ENSMUST00000091137
Protein Domains
Calx-beta

Promoters
RGD ID:6833795
Promoter ID:MM_KWN:34317
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   Kidney,   Spleen
Transcripts:NM_172862
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36353,460,366 - 53,461,367 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444465 AgrOrtholog
Ensembl Genes ENSMUSG00000037016 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000088670 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000091137 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.2030 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CalX-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calx_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CSPG_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FRAS1-rel_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:242022 UniProtKB/Swiss-Prot
MGD MGI:2444465 ENTREZGENE
NCBI Gene 242022 ENTREZGENE
PANTHER FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATRIX PROTEIN, PUTATIVE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cadherin_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calx-beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Frem_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Frem2 PhenoGen
PROSITE CSPG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Calx_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF141072 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt FREM2_MOUSE UniProtKB/Swiss-Prot
  Q1XGY5 ENTREZGENE, UniProtKB/TrEMBL
  Q4W2Q5 ENTREZGENE
  Q5H8C0 ENTREZGENE
  Q6NVD0 ENTREZGENE
  Q811G9 ENTREZGENE
  Q8C4G5 ENTREZGENE
  Q8CD46 ENTREZGENE
UniProt Secondary Q4W2Q5 UniProtKB/Swiss-Prot
  Q5H8C0 UniProtKB/Swiss-Prot
  Q811G9 UniProtKB/Swiss-Prot
  Q8C4G5 UniProtKB/Swiss-Prot
  Q8CD46 UniProtKB/Swiss-Prot