Nelfe (negative elongation factor complex member E, Rdbp) - Rat Genome Database

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Gene: Nelfe (negative elongation factor complex member E, Rdbp) Mus musculus
Analyze
Symbol: Nelfe
Name: negative elongation factor complex member E, Rdbp
RGD ID: 1621569
MGI Page MGI
Description: Enables chromatin binding activity. Involved in negative regulation of transcription elongation by RNA polymerase II. Is active in chromatin. Is expressed in brain and early conceptus. Orthologous to human NELFE (negative elongation factor complex member E).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D17H6S45; negative elongation factor E; NELF; NELF-E; RD; RD RNA-binding protein; Rdbp; RNA-binding protein RD
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,069,367 - 35,075,348 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,069,367 - 35,075,348 (+)EnsemblGRCm39 Ensembl
GRCm381734,850,391 - 34,856,372 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,850,391 - 34,856,372 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,987,336 - 34,993,317 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,458,975 - 34,464,214 (+)NCBIMGSCv36mm8
Celera1737,945,699 - 37,951,680 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IDA,ISO)
NELF complex  (IBA,ISO,ISS)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (ISO)
plasma membrane  (IEA,ISO)

Molecular Function
chromatin binding  (IDA,ISO)
mRNA binding  (IEA,ISO)
protein binding  (IPI)
RNA binding  (ISO,ISS)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Control of transcriptional elongation. Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3353717   PMID:8373374   PMID:9321489   PMID:10349636   PMID:10686478   PMID:10871872   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932  
PMID:14610273   PMID:14656967   PMID:15489334   PMID:15749018   PMID:15782199   PMID:16033648   PMID:16141072   PMID:16141073   PMID:17015433   PMID:18799693   PMID:19723774   PMID:21267068  
PMID:21670248   PMID:21677750   PMID:21873635   PMID:22579285   PMID:26010750   PMID:26244796   PMID:29847629   PMID:30196744   PMID:30973865   PMID:31399344   PMID:31406667   PMID:32325033  
PMID:34133714   PMID:36577375   PMID:38355793  


Genomics

Comparative Map Data
Nelfe
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,069,367 - 35,075,348 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,069,367 - 35,075,348 (+)EnsemblGRCm39 Ensembl
GRCm381734,850,391 - 34,856,372 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,850,391 - 34,856,372 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,987,336 - 34,993,317 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,458,975 - 34,464,214 (+)NCBIMGSCv36mm8
Celera1737,945,699 - 37,951,680 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.4NCBI
NELFE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,952,087 - 31,958,971 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,952,087 - 31,959,038 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,919,864 - 31,926,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,027,843 - 32,034,843 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,027,843 - 32,034,747NCBI
Celera633,519,627 - 33,526,530 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,706,833 - 31,713,834 (-)NCBIHuRef
CHM1_1631,921,945 - 31,928,945 (-)NCBICHM1_1
T2T-CHM13v2.0631,805,292 - 31,812,176 (-)NCBIT2T-CHM13v2.0
Nelfe
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,981,259 - 3,987,016 (-)NCBIGRCr8
mRatBN7.2203,976,512 - 3,982,389 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,976,518 - 3,982,355 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,676,633 - 4,682,383 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,038,381 - 4,044,131 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,575,547 - 4,581,290 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,530,328 - 4,536,085 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,530,342 - 4,536,209 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,610,127 - 6,615,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,077,925 - 4,081,561 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,078,021 - 4,081,787 (-)NCBI
Celera204,048,306 - 4,054,061 (+)NCBICelera
Cytogenetic Map20p12NCBI
Nelfe
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437466,690 - 473,084 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437467,018 - 473,084 (-)NCBIChiLan1.0ChiLan1.0
NELFE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,428,781 - 46,435,590 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,390,268 - 42,397,077 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,612,924 - 31,619,732 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,499,538 - 32,506,382 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,499,540 - 32,506,382 (-)Ensemblpanpan1.1panPan2
NELFE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,406,411 - 1,412,387 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,406,271 - 1,412,324 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,541,468 - 1,547,598 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,548,568 - 1,554,700 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,548,568 - 1,554,605 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,405,843 - 1,411,974 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,474,213 - 1,480,345 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,539,542 - 1,546,943 (-)NCBIUU_Cfam_GSD_1.0
Nelfe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,965,333 - 35,971,346 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,589,942 - 1,598,182 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,589,942 - 1,596,009 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NELFE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,040,525 - 24,047,025 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,040,525 - 24,046,932 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,765,281 - 27,771,676 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NELFE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,063,298 - 40,069,714 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,063,755 - 40,198,451 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,868,805 - 31,875,524 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nelfe
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,300,602 - 24,310,671 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,300,012 - 24,310,777 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1473
Count of miRNA genes:631
Interacting mature miRNAs:762
Transcripts:ENSMUST00000097343, ENSMUST00000165953, ENSMUST00000173065, ENSMUST00000173357, ENSMUST00000173775, ENSMUST00000174075, ENSMUST00000174888
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1302189Dps3_mdelta power in slow-wave sleep 3 (mouse)Not determined173381972136250180Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173206165237644775Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
25394538Skmw84_mskeletal muscle weight 84, TA (mouse)173266042635520036Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1301759Sles1_msystemic lupus erythmatosus suppressor 1 (mouse)Not determined173421989035175937Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
AI255840  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,856,482 - 34,856,579UniSTSGRCm38
MGSCv371734,993,427 - 34,993,524UniSTSGRCm37
Celera1737,951,790 - 37,951,887UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.85UniSTS
cM Map1718.84UniSTS
Whitehead/MRC_RH17468.4UniSTS
Rdbp  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17B1UniSTS
cM Map1718.84UniSTS
cM Map1718.4UniSTS
D17916  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,856,410 - 34,856,582UniSTSGRCm38
MGSCv371734,993,355 - 34,993,527UniSTSGRCm37
Celera1737,951,718 - 37,951,890UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.85UniSTS
cM Map1718.84UniSTS
Whitehead_YAC17 UniSTS
Cfb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,856,462 - 34,856,534UniSTSGRCm38
MGSCv371734,993,407 - 34,993,479UniSTSGRCm37
Celera1737,951,770 - 37,951,842UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.41UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001045863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001045864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF049850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF109906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI325150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN525174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT573030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU406965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU463176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX203833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV662511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF437332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M21332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U83841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U83842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000097343   ⟹   ENSMUSP00000094956
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,069,367 - 35,075,345 (+)Ensembl
GRCm38.p6 Ensembl1734,850,391 - 34,856,369 (+)Ensembl
Ensembl Acc Id: ENSMUST00000165953   ⟹   ENSMUSP00000131195
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,069,384 - 35,075,348 (+)Ensembl
GRCm38.p6 Ensembl1734,850,408 - 34,856,372 (+)Ensembl
Ensembl Acc Id: ENSMUST00000173065   ⟹   ENSMUSP00000133934
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,069,384 - 35,073,065 (+)Ensembl
GRCm38.p6 Ensembl1734,850,408 - 34,854,089 (+)Ensembl
Ensembl Acc Id: ENSMUST00000173357   ⟹   ENSMUSP00000134272
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,069,374 - 35,075,230 (+)Ensembl
GRCm38.p6 Ensembl1734,850,398 - 34,856,254 (+)Ensembl
Ensembl Acc Id: ENSMUST00000173775
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,071,584 - 35,072,845 (+)Ensembl
GRCm38.p6 Ensembl1734,852,608 - 34,853,869 (+)Ensembl
Ensembl Acc Id: ENSMUST00000174075
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,073,232 - 35,073,730 (+)Ensembl
GRCm38.p6 Ensembl1734,854,256 - 34,854,754 (+)Ensembl
Ensembl Acc Id: ENSMUST00000174888
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,072,912 - 35,073,502 (+)Ensembl
GRCm38.p6 Ensembl1734,853,936 - 34,854,526 (+)Ensembl
RefSeq Acc Id: NM_001045863   ⟹   NP_001039328
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391735,069,367 - 35,075,348 (+)NCBI
GRCm381734,850,391 - 34,856,372 (+)NCBI
MGSCv371734,987,336 - 34,993,317 (+)RGD
Celera1737,945,699 - 37,951,680 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001045864   ⟹   NP_001039329
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391735,069,367 - 35,075,348 (+)NCBI
GRCm381734,850,391 - 34,856,372 (+)NCBI
MGSCv371734,987,336 - 34,993,317 (+)RGD
Celera1737,945,699 - 37,951,680 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_138580   ⟹   NP_613046
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391735,069,367 - 35,075,348 (+)NCBI
GRCm381734,850,391 - 34,856,372 (+)NCBI
MGSCv371734,987,336 - 34,993,317 (+)RGD
Celera1737,945,699 - 37,951,680 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_001039329   ⟸   NM_001045864
- UniProtKB: P19426 (UniProtKB/Swiss-Prot),   Q9CZN3 (UniProtKB/Swiss-Prot),   P97486 (UniProtKB/Swiss-Prot),   P97485 (UniProtKB/Swiss-Prot),   Q3UIA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001039328   ⟸   NM_001045863
- UniProtKB: P19426 (UniProtKB/Swiss-Prot),   Q9CZN3 (UniProtKB/Swiss-Prot),   P97486 (UniProtKB/Swiss-Prot),   P97485 (UniProtKB/Swiss-Prot),   Q3UIA1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_613046   ⟸   NM_138580
- UniProtKB: P19426 (UniProtKB/Swiss-Prot),   Q9CZN3 (UniProtKB/Swiss-Prot),   P97486 (UniProtKB/Swiss-Prot),   P97485 (UniProtKB/Swiss-Prot),   Q3UIA1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000131195   ⟸   ENSMUST00000165953
Ensembl Acc Id: ENSMUSP00000134272   ⟸   ENSMUST00000173357
Ensembl Acc Id: ENSMUSP00000133934   ⟸   ENSMUST00000173065
Ensembl Acc Id: ENSMUSP00000094956   ⟸   ENSMUST00000097343
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P19426-F1-model_v2 AlphaFold P19426 1-375 view protein structure

Promoters
RGD ID:13675746
Promoter ID:EPDNEW_M22022
Type:initiation region
Name:Nelfe_1
Description:Mus musculus negative elongation factor complex member E, Rdbp, transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381734,850,410 - 34,850,470EPDNEW
RGD ID:6828558
Promoter ID:MM_KWN:23229
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:NM_001045863,   NM_001045864,   NM_021337,   NM_138580,   UC008CDT.1,   UC008CDU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361734,986,976 - 34,988,107 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102744 AgrOrtholog
Ensembl Genes ENSMUSG00000024369 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000097343 ENTREZGENE
  ENSMUST00000097343.11 UniProtKB/Swiss-Prot
  ENSMUST00000165953 ENTREZGENE
  ENSMUST00000165953.3 UniProtKB/Swiss-Prot
  ENSMUST00000173065.8 UniProtKB/TrEMBL
  ENSMUST00000173357 ENTREZGENE
  ENSMUST00000173357.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NELFE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NELFE_RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:27632 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:102744 ENTREZGENE
NCBI Gene 27632 ENTREZGENE
PANTHER NEGATIVE ELONGATION FACTOR E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR17250 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nelfe PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3UY39_MOUSE UniProtKB/TrEMBL
  NELFE_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  P97485 ENTREZGENE
  P97486 ENTREZGENE
  Q3UIA1 ENTREZGENE, UniProtKB/TrEMBL
  Q9CZN3 ENTREZGENE
UniProt Secondary P97485 UniProtKB/Swiss-Prot
  P97486 UniProtKB/Swiss-Prot
  Q9CZN3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-12 Nelfe  negative elongation factor complex member E, Rdbp  Rdbp  RD RNA-binding protein  Symbol and/or name change 5135510 APPROVED