Speer6-ps1 (spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1) - Rat Genome Database

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Gene: Speer6-ps1 (spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1) Mus musculus
Symbol: Speer6-ps1
Name: spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1
RGD ID: 1620748
Description: ASSOCIATED WITH abdomen swellings; abnormal acetaminophen metabolism; abnormal aerobic respiration; INTERACTS WITH 1,2-dichloroethane; Benoxacor; trimellitic anhydride
Type: pseudo (Ensembl: lncRNA)
Previously known as: 1700039A02Rik; Alb-cre; Alb; AlbCre; albumin-cre; cr; SPEE; SPEER-6; Tg(Alb-cre)21Mgn
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39133,199,475 - 3,239,678 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,199,475 - 3,239,678 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl133,236,206 - 3,239,317 (+)EnsemblGRCm39 Ensembl
GRCm38133,149,475 - 3,189,678 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,149,475 - 3,189,678 (+)EnsemblGRCm38mm10GRCm38
MGSCv37133,148,721 - 3,188,924 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,148,721 - 3,188,924 (+)NCBIMGSCv36mm8
Celera133,135,860 - 3,175,371 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map131.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abdomen swellings  (IAGP)
abnormal acetaminophen metabolism  (IAGP)
abnormal aerobic respiration  (IAGP)
abnormal amino acid metabolism  (IAGP)
abnormal apolipoprotein level  (IAGP)
abnormal autophagosome formation  (IAGP)
abnormal autophagy  (IAGP)
abnormal B cell differentiation  (IAGP)
abnormal bile canaliculus morphology  (IAGP)
abnormal bile composition  (IAGP)
abnormal bile duct development  (IAGP)
abnormal bile duct epithelium morphology  (IAGP)
abnormal bile duct morphology  (IAGP)
abnormal bile duct physiology  (IAGP)
abnormal bile salt homeostasis  (IAGP)
abnormal bile salt level  (IAGP)
abnormal bile secretion  (IAGP)
abnormal blood coagulation  (IAGP)
abnormal blood homeostasis  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal carbohydrate metabolism  (IAGP)
abnormal cell differentiation  (IAGP)
abnormal cell migration  (IAGP)
abnormal cell morphology  (IAGP)
abnormal cell physiology  (IAGP)
abnormal cellular cholesterol metabolism  (IAGP)
abnormal cellular replicative senescence  (IAGP)
abnormal cellular respiration  (IAGP)
abnormal cholangiocyte morphology  (IAGP)
abnormal cholesterol homeostasis  (IAGP)
abnormal circulating alanine transaminase level  (IAGP)
abnormal circulating amino acid level  (IAGP)
abnormal circulating apolipoprotein level  (IAGP)
abnormal circulating cholesterol level  (IAGP)
abnormal circulating enzyme level  (IAGP)
abnormal circulating ketone body level  (IAGP)
abnormal circulating phospholipid level  (IAGP)
abnormal circulating serum albumin level  (IAGP)
abnormal DNA replication  (IAGP)
abnormal eating behavior  (IAGP)
abnormal endocytosis  (IAGP)
abnormal endoplasmic reticulum morphology  (IAGP)
abnormal energy homeostasis  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal enzyme/coenzyme level  (IAGP)
abnormal fat pad morphology  (IAGP)
abnormal fatty acid beta-oxidation  (IAGP)
abnormal fatty acid oxidation  (IAGP)
abnormal fatty acids level  (IAGP)
abnormal fear-related response  (IAGP)
abnormal feces composition  (IAGP)
abnormal feces lipid level  (IAGP)
abnormal gait  (IAGP)
abnormal gluconeogenesis  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal glucose tolerance  (IAGP)
abnormal glycogen homeostasis  (IAGP)
abnormal heart echocardiography feature  (IAGP)
abnormal hepatic cord morphology  (IAGP)
abnormal hepatic duct morphology  (IAGP)
abnormal hepatobiliary system development  (IAGP)
abnormal hepatobiliary system physiology  (IAGP)
abnormal hepatoblast differentiation  (IAGP)
abnormal hepatocyte mitochondrial morphology  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal hepatocyte physiology  (IAGP)
abnormal homeostasis  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal insulin clearance  (IAGP)
abnormal insulin secretion  (IAGP)
abnormal intestinal cholesterol absorption  (IAGP)
abnormal intrahepatic bile duct morphology  (IAGP)
abnormal iron homeostasis  (IAGP)
abnormal Ito cell morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal lipid level  (IAGP)
abnormal lipid oxidation  (IAGP)
abnormal liver development  (IAGP)
abnormal liver lobule morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal liver parenchyma morphology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal liver regeneration  (IAGP)
abnormal liver sinusoid morphology  (IAGP)
abnormal lysosome morphology  (IAGP)
abnormal macrophage morphology  (IAGP)
abnormal metabolism  (IAGP)
abnormal mitochondrial ATP synthesis coupled electron transport  (IAGP)
abnormal mitochondrial crista morphology  (IAGP)
abnormal mitochondrial inner membrane morphology  (IAGP)
abnormal mitochondrial morphology  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal mitochondrial shape  (IAGP)
abnormal mitophagy  (IAGP)
abnormal mitosis  (IAGP)
abnormal NK T cell physiology  (IAGP)
abnormal nucleotide metabolism  (IAGP)
abnormal oval cell morphology  (IAGP)
abnormal oval cell physiology  (IAGP)
abnormal oxidative phosphorylation  (IAGP)
abnormal pancreatic beta cell physiology  (IAGP)
abnormal phospholipid level  (IAGP)
abnormal physiological response to hypoxia  (IAGP)
abnormal phytosterol level  (IAGP)
abnormal portal lobule morphology  (IAGP)
abnormal portal triad morphology  (IAGP)
abnormal postnatal growth  (IAGP)
abnormal redox activity  (IAGP)
abnormal respiratory electron transport chain  (IAGP)
abnormal response to injury  (IAGP)
abnormal selenium level  (IAGP)
abnormal snout skin morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal sterol level  (IAGP)
abnormal susceptibility to injury induced morbidity/mortality  (IAGP)
abnormal thrombosis  (IAGP)
abnormal thymus development  (IAGP)
abnormal tricarboxylic acid cycle  (IAGP)
abnormal triglyceride level  (IAGP)
abnormal urine homeostasis  (IAGP)
abnormal vasodilation  (IAGP)
abnormal xenobiotic pharmacokinetics  (IAGP)
anemia  (IAGP)
aneuploidy  (IAGP)
bile duct hyperplasia  (IAGP)
bile duct inflammation  (IAGP)
bile duct proliferation  (IAGP)
cachexia  (IAGP)
calcified skin  (IAGP)
calcinosis  (IAGP)
cardiac fibrosis  (IAGP)
cholestasis  (IAGP)
decreased acute inflammation  (IAGP)
decreased B cell number  (IAGP)
decreased basal metabolism  (IAGP)
decreased bile salt level  (IAGP)
decreased blood urea nitrogen level  (IAGP)
decreased body fat mass  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased brown adipose tissue amount  (IAGP)
decreased brown fat cell lipid droplet size  (IAGP)
decreased cardiac muscle cell glucose uptake  (IAGP)
decreased cholesterol efflux  (IAGP)
decreased circulating alanine transaminase level  (IAGP)
decreased circulating alkaline phosphatase level  (IAGP)
decreased circulating amylase level  (IAGP)
decreased circulating aspartate transaminase level  (IAGP)
decreased circulating calcium level  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating corticosterone level  (IAGP)
decreased circulating creatinine level  (IAGP)
decreased circulating cysteine level  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating glucagon level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating glycerol level  (IAGP)
decreased circulating HDL cholesterol level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating insulin-like growth factor I level  (IAGP)
decreased circulating ketone body level  (IAGP)
decreased circulating LDL cholesterol level  (IAGP)
decreased circulating leptin level  (IAGP)
decreased circulating phospholipid level  (IAGP)
decreased circulating serum albumin level  (IAGP)
decreased circulating thyroxine level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased circulating unsaturated transferrin level  (IAGP)
decreased circulating VLDL cholesterol level  (IAGP)
decreased circulating VLDL phospholipid level  (IAGP)
decreased circulating VLDL triglyceride level  (IAGP)
decreased cysteine level  (IAGP)
decreased double-negative T cell number  (IAGP)
decreased fasting circulating glucose level  (IAGP)
decreased fat cell size  (IAGP)
decreased fatty acid beta-oxidation  (IAGP)
decreased fatty acid oxidation  (IAGP)
decreased fatty acids level  (IAGP)
decreased glycogen catabolism rate  (IAGP)
decreased glycogen level  (IAGP)
decreased gonadal fat pad weight  (IAGP)
decreased heart weight  (IAGP)
decreased hepatic glucose production  (IAGP)
decreased hepatocyte number  (IAGP)
decreased hepatocyte proliferation  (IAGP)
decreased incidence of induced tumors  (IAGP)
decreased incidence of tumors by chemical induction  (IAGP)
decreased inguinal fat pad weight  (IAGP)
decreased insulin secretion  (IAGP)
decreased intestinal cholesterol absorption  (IAGP)
decreased kidney copper level  (IAGP)
decreased kidney weight  (IAGP)
decreased lean body mass  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased litter size  (IAGP)
decreased liver cholesterol level  (IAGP)
decreased liver copper level  (IAGP)
decreased liver free fatty acids level  (IAGP)
decreased liver function  (IAGP)
decreased liver glycogen level  (IAGP)
decreased liver iron level  (IAGP)
decreased liver manganese level  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased liver tumor incidence  (IAGP)
decreased liver weight  (IAGP)
decreased locomotor activity  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased mitochondrial number  (IAGP)
decreased NK T cell number  (IAGP)
decreased pancreatic beta cell mass  (IAGP)
decreased percent body fat/body weight  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased phytosterol level  (IAGP)
decreased respiratory quotient  (IAGP)
decreased retroperitoneal fat pad weight  (IAGP)
decreased saturated fatty acids level  (IAGP)
decreased spleen iron level  (IAGP)
decreased spleen white pulp amount  (IAGP)
decreased susceptibility to age-related hepatic steatosis  (IAGP)
decreased susceptibility to atherosclerosis  (IAGP)
decreased susceptibility to diet-induced hepatic steatosis  (IAGP)
decreased susceptibility to diet-induced obesity  (IAGP)
decreased susceptibility to hepatic steatosis  (IAGP)
decreased susceptibility to injury  (IAGP)
decreased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
decreased systemic arterial diastolic blood pressure  (IAGP)
decreased T cell number  (IAGP)
decreased total body fat amount  (IAGP)
decreased total fat pad weight  (IAGP)
decreased triglyceride lipase activity  (IAGP)
decreased unsaturated fatty acids level  (IAGP)
decreased urine uric acid level  (IAGP)
decreased white adipose tissue amount  (IAGP)
decreased white adipose tissue mass  (IAGP)
decreased white fat cell lipid droplet size  (IAGP)
dilated bile duct  (IAGP)
dilated mitochondrion  (IAGP)
distended abdomen  (IAGP)
enhanced autophagy  (IAGP)
enhanced behavioral response to xenobiotic  (IAGP)
enhanced lipolysis  (IAGP)
enlarged adrenal glands  (IAGP)
enlarged gallbladder  (IAGP)
enlarged liver  (IAGP)
enlarged spleen  (IAGP)
female infertility  (IAGP)
focal hepatic necrosis  (IAGP)
genetic imprinting  (IAGP)
granulomatous inflammation  (IAGP)
hemochromatosis  (IAGP)
hemoperitoneum  (IAGP)
hemorrhagic ascites  (IAGP)
hemosiderosis  (IAGP)
hepatic necrosis  (IAGP)
hepatic steatosis  (IAGP)
hyperactivity  (IAGP)
hyperglycemia  (IAGP)
hypoglycemia  (IAGP)
impaired autophagy  (IAGP)
impaired blood coagulation  (IAGP)
impaired exercise endurance  (IAGP)
impaired gluconeogenesis  (IAGP)
impaired glucose tolerance  (IAGP)
impaired lipolysis  (IAGP)
impaired liver regeneration  (IAGP)
impaired wound healing  (IAGP)
improved glucose tolerance  (IAGP)
increased acute inflammation  (IAGP)
increased alkaline phosphatase activity  (IAGP)
increased anti-nuclear antigen antibody level  (IAGP)
increased apoptosis  (IAGP)
increased autoantibody level  (IAGP)
increased bile salt level  (IAGP)
increased bleeding time  (IAGP)
increased body surface temperature  (IAGP)
increased body weight  (IAGP)
increased brown fat lipid droplet number  (IAGP)
increased carbon dioxide production  (IAGP)
increased carcinoma incidence  (IAGP)
increased cell nucleus count  (IAGP)
increased cellular glucose import  (IAGP)
increased cholangiocarcinoma incidence  (IAGP)
increased cholesterol level  (IAGP)
increased circulating alanine transaminase level  (IAGP)
increased circulating alkaline phosphatase level  (IAGP)
increased circulating ammonia level  (IAGP)
increased circulating aspartate transaminase level  (IAGP)
increased circulating bilirubin level  (IAGP)
increased circulating carnitine level  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating ferritin level  (IAGP)
increased circulating free fatty acids level  (IAGP)
increased circulating glucagon level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating growth hormone level  (IAGP)
increased circulating HDL cholesterol level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating interleukin-1 beta level  (IAGP)
increased circulating interleukin-18 level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased circulating iron level  (IAGP)
increased circulating ketone body level  (IAGP)
increased circulating lactate dehydrogenase level  (IAGP)
increased circulating lactate level  (IAGP)
increased circulating LDL cholesterol level  (IAGP)
increased circulating lysine level  (IAGP)
increased circulating methionine level  (IAGP)
increased circulating phospholipid level  (IAGP)
increased circulating phytosterol level  (IAGP)
increased circulating progesterone level  (IAGP)
increased circulating proline level  (IAGP)
increased circulating serine level  (IAGP)
increased circulating testosterone level  (IAGP)
increased circulating threonine level  (IAGP)
increased circulating thyroxine level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased circulating triiodothyronine level  (IAGP)
increased energy expenditure  (IAGP)
increased fasting circulating glucose level  (IAGP)
increased fatty acid oxidation  (IAGP)
increased fatty acids level  (IAGP)
increased feces cholesterol level  (IAGP)
increased hamartoma incidence  (IAGP)
increased hematocrit  (IAGP)
increased hepatobiliary system tumor incidence  (IAGP)
increased hepatocellular carcinoma incidence  (IAGP)
increased hepatocyte apoptosis  (IAGP)
increased hepatocyte karyomegaly  (IAGP)
increased hepatocyte mitochondrial DNA content  (IAGP)
increased hepatocyte number  (IAGP)
increased hepatocyte proliferation  (IAGP)
increased hepatoma incidence  (IAGP)
increased IgG level  (IAGP)
increased IgM level  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased insulin secretion  (IAGP)
increased insulin sensitivity  (IAGP)
increased interleukin-6 secretion  (IAGP)
increased kidney weight  (IAGP)
increased lean body mass  (IAGP)
increased lipogenesis  (IAGP)
increased liver adenoma incidence  (IAGP)
increased liver cholesterol level  (IAGP)
increased liver copper level  (IAGP)
increased liver free fatty acids level  (IAGP)
increased liver glycogen level  (IAGP)
increased liver iron level  (IAGP)
increased liver triglyceride level  (IAGP)
increased liver tumor incidence  (IAGP)
increased liver weight  (IAGP)
increased metastatic potential  (IAGP)
increased mitochondrial DNA content  (IAGP)
increased mitochondrial number  (IAGP)
increased mitochondrial size  (IAGP)
increased monocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased oxygen consumption  (IAGP)
increased pancreas weight  (IAGP)
increased pancreatic alpha cell number  (IAGP)
increased pancreatic alpha cell proliferation  (IAGP)
increased pancreatic beta cell mass  (IAGP)
increased partial thromboplastin time  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased prothrombin time  (IAGP)
increased respiratory quotient  (IAGP)
increased saturated fatty acids level  (IAGP)
increased spleen iron level  (IAGP)
increased susceptibility to atherosclerosis  (IAGP)
increased susceptibility to autoimmune diabetes  (IAGP)
increased susceptibility to bacterial infection induced morbidity/mortality  (IAGP)
increased susceptibility to diet-induced hepatic steatosis  (IAGP)
increased susceptibility to diet-induced obesity  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased susceptibility to injury  (IAGP)
increased susceptibility to weight gain  (IAGP)
increased susceptibility to weight loss  (IAGP)
increased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
increased triglyceride level  (IAGP)
increased tumor latency  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
increased unsaturated fatty acids level  (IAGP)
increased urine selenium level  (IAGP)
increased vascular endothelial cell number  (IAGP)
insulin resistance  (IAGP)
intrahepatic cholestasis  (IAGP)
jaundice  (IAGP)
lethargy  (IAGP)
limb grasping  (IAGP)
liver cirrhosis  (IAGP)
liver failure  (IAGP)
liver fibrosis  (IAGP)
liver hemorrhage  (IAGP)
liver hyperplasia  (IAGP)
liver inflammation  (IAGP)
macrovesicular hepatic steatosis  (IAGP)
Mallory bodies  (IAGP)
microvesicular hepatic steatosis  (IAGP)
no abnormal phenotype detected  (IAGP)
oligozoospermia  (IAGP)
oxidative stress  (IAGP)
pale liver  (IAGP)
pancreatic islet hyperplasia  (IAGP)
patent ductus venosus  (IAGP)
paternal imprinting  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
polycythemia  (IAGP)
polydipsia  (IAGP)
polyploidy  (IAGP)
polyuria  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
pregnancy-related premature death  (IAGP)
premature death  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
prolonged PR interval  (IAGP)
prolonged QRS complex duration  (IAGP)
reddish skin  (IAGP)
reduced fertility  (IAGP)
reticulocytosis  (IAGP)
slow movement  (IAGP)
slow postnatal weight gain  (IAGP)
small liver  (IAGP)
spleen atrophy  (IAGP)
subcutaneous hemorrhage  (IAGP)
teratozoospermia  (IAGP)
uterine hemorrhage  (IAGP)
vaginal hemorrhage  (IAGP)
weight loss  (IAGP)

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9867845   PMID:10349636   PMID:10686614   PMID:10825207   PMID:10866673   PMID:10938127   PMID:10949030   PMID:11042159   PMID:11076861   PMID:11108252   PMID:11171994   PMID:11217851  
PMID:11287642   PMID:11557972   PMID:11909940   PMID:12176043   PMID:12466851   PMID:12482952   PMID:12507915   PMID:12529398   PMID:12538623   PMID:12566435   PMID:12588884   PMID:12606357  
PMID:12697746   PMID:12829628   PMID:12929087   PMID:14550306   PMID:14613934   PMID:14614859   PMID:14660662   PMID:14749836   PMID:14769918   PMID:14985368   PMID:15070743   PMID:15082532  
PMID:15199412   PMID:15331603   PMID:15347677   PMID:15372107   PMID:15389868   PMID:15480996   PMID:15569412   PMID:15638810   PMID:15687502   PMID:15717863   PMID:15732085   PMID:15735717  
PMID:15738389   PMID:15798202   PMID:15821749   PMID:15841208   PMID:15899812   PMID:15908240   PMID:15930274   PMID:15958390   PMID:15989949   PMID:16006652   PMID:16054078   PMID:16122419  
PMID:16141072   PMID:16141073   PMID:16155866   PMID:16202981   PMID:16214396   PMID:16278235   PMID:16293230   PMID:16301529   PMID:16374520   PMID:16382155   PMID:16404553   PMID:16449639  
PMID:16467350   PMID:16469705   PMID:16527892   PMID:16543947   PMID:16557553   PMID:16679292   PMID:16710476   PMID:16717184   PMID:16738330   PMID:16804073   PMID:16807293   PMID:16831601  
PMID:16845389   PMID:16880400   PMID:16921198   PMID:16940190   PMID:16946132   PMID:16964311   PMID:16977322   PMID:17030618   PMID:17101329   PMID:17151194   PMID:17200715   PMID:17256747  
PMID:17283057   PMID:17295835   PMID:17374357   PMID:17404621   PMID:17416680   PMID:17442273   PMID:17464988   PMID:17556363   PMID:17557118   PMID:17567478   PMID:17570221   PMID:17597094  
PMID:17646385   PMID:17699762   PMID:17699788   PMID:17854601   PMID:17904103   PMID:17908794   PMID:17942915   PMID:17951359   PMID:17996733   PMID:17998203   PMID:18026104   PMID:18042552  
PMID:18054317   PMID:18083104   PMID:18201277   PMID:18249172   PMID:18316028   PMID:18322014   PMID:18323469   PMID:18325391   PMID:18354499   PMID:18365007   PMID:18373496   PMID:18395093  
PMID:18417483   PMID:18426910   PMID:18434600   PMID:18437205   PMID:18511518   PMID:18573907   PMID:18583462   PMID:18587407   PMID:18590692   PMID:18590693   PMID:18639551   PMID:18666258  
PMID:18669658   PMID:18677409   PMID:18691550   PMID:18692468   PMID:18694957   PMID:18778245   PMID:18784258   PMID:18805792   PMID:18820241   PMID:18826952   PMID:18952117   PMID:19052228  
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