Sppl3 (signal peptide peptidase 3) - Rat Genome Database

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Gene: Sppl3 (signal peptide peptidase 3) Mus musculus
Analyze
Symbol: Sppl3
Name: signal peptide peptidase 3
RGD ID: 1620736
MGI Page MGI
Description: Predicted to enable aspartic endopeptidase activity, intramembrane cleaving and protein homodimerization activity. Involved in T cell receptor signaling pathway; positive regulation of calcineurin-NFAT signaling cascade; and positive regulation of cytosolic calcium ion concentration. Located in endoplasmic reticulum-Golgi intermediate compartment membrane. Is expressed in central nervous system; gonad; retina; and vibrissa. Orthologous to human SPPL3 (signal peptide peptidase like 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4833416I09Rik; IMP-2; intramembrane protease 2; MGC90867; presenilin-like protein 4; Psl4; signal peptide peptidase-like 3; SPP-like 3 protein; upregulated during skeletal muscle growth 3; Usmg; Usmg3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,149,204 - 115,236,849 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,149,196 - 115,236,849 (+)EnsemblGRCm39 Ensembl
GRCm385115,011,524 - 115,098,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,011,137 - 115,098,790 (+)EnsemblGRCm38mm10GRCm38
MGSCv375115,461,533 - 115,548,799 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,272,523 - 115,359,789 (+)NCBIMGSCv36mm8
Celera5112,107,828 - 112,194,819 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11044607   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15582152  
PMID:16141072   PMID:16141073   PMID:16602821   PMID:18799693   PMID:20562862   PMID:21267068   PMID:21677750   PMID:21873635   PMID:25354954   PMID:25384971   PMID:25827571   PMID:26851218  
PMID:32554809   PMID:38355793  


Genomics

Comparative Map Data
Sppl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,149,204 - 115,236,849 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,149,196 - 115,236,849 (+)EnsemblGRCm39 Ensembl
GRCm385115,011,524 - 115,098,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,011,137 - 115,098,790 (+)EnsemblGRCm38mm10GRCm38
MGSCv375115,461,533 - 115,548,799 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,272,523 - 115,359,789 (+)NCBIMGSCv36mm8
Celera5112,107,828 - 112,194,819 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.99NCBI
SPPL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812120,762,510 - 120,904,358 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12120,762,510 - 120,904,358 (-)EnsemblGRCh38hg38GRCh38
GRCh3712121,200,313 - 121,342,161 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,685,418 - 119,826,534 (-)NCBINCBI36Build 36hg18NCBI36
Celera12120,835,168 - 120,976,050 (-)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12118,209,451 - 118,351,576 (-)NCBIHuRef
CHM1_112121,169,084 - 121,310,844 (-)NCBICHM1_1
T2T-CHM13v2.012120,751,646 - 120,893,446 (-)NCBIT2T-CHM13v2.0
Sppl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,176,317 - 47,260,756 (-)NCBIGRCr8
mRatBN7.21241,515,635 - 41,600,079 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,515,640 - 41,600,126 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01247,276,485 - 47,360,552 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,276,476 - 47,360,507 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01249,071,961 - 49,156,613 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,788,576 - 42,882,650 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1243,134,305 - 43,170,708 (-)NCBICelera
Cytogenetic Map12q16NCBI
Sppl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,760,804 - 10,907,024 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,849,627 - 10,905,515 (+)NCBIChiLan1.0ChiLan1.0
SPPL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,837,951 - 128,976,306 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,834,324 - 128,972,679 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,351,199 - 118,489,579 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,723,881 - 121,858,502 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,723,881 - 121,773,429 (-)Ensemblpanpan1.1panPan2
SPPL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,620,236 - 16,760,616 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,621,455 - 16,760,623 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,622,725 - 16,762,963 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,886,222 - 17,026,542 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2616,887,266 - 17,026,468 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12616,847,005 - 16,987,200 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,922,683 - 17,062,392 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,965,017 - 17,105,003 (-)NCBIUU_Cfam_GSD_1.0
Sppl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118145,694,867 - 145,731,325 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936668193,723 - 231,088 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936668193,753 - 229,859 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPPL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,699,937 - 40,822,761 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,699,931 - 40,870,288 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21443,167,682 - 43,217,584 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPPL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111116,125,042 - 116,267,226 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11116,124,221 - 116,267,108 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037128,831,057 - 128,972,698 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sppl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,795,563 - 12,928,649 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474712,795,803 - 12,925,319 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sppl3
4170 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:890
Count of miRNA genes:545
Interacting mature miRNAs:660
Transcripts:ENSMUST00000031530, ENSMUST00000128590, ENSMUST00000128678, ENSMUST00000150708
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5103047866115538059Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined598019649116876624Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5114021753129632606Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4141652Mrdq2_mmodifier of retinal degeneration QTL 2 (mouse)Not determined110253106118093673Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108762509126882944Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse

Markers in Region
UniSTS:235278  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385115,040,874 - 115,041,043UniSTSGRCm38
MGSCv375115,490,883 - 115,491,052UniSTSGRCm37
Celera5112,136,880 - 112,137,049UniSTS
Cytogenetic Map5FUniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000031530   ⟹   ENSMUSP00000031530
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5115,149,196 - 115,236,849 (+)Ensembl
GRCm38.p6 Ensembl5115,011,137 - 115,098,790 (+)Ensembl
Ensembl Acc Id: ENSMUST00000128590   ⟹   ENSMUSP00000143889
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5115,149,556 - 115,222,944 (+)Ensembl
GRCm38.p6 Ensembl5115,011,497 - 115,084,885 (+)Ensembl
Ensembl Acc Id: ENSMUST00000128678
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5115,232,816 - 115,236,315 (+)Ensembl
GRCm38.p6 Ensembl5115,094,757 - 115,098,256 (+)Ensembl
Ensembl Acc Id: ENSMUST00000150708
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5115,149,205 - 115,199,660 (+)Ensembl
GRCm38.p6 Ensembl5115,011,146 - 115,061,601 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201970
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5115,212,426 - 115,214,931 (+)Ensembl
GRCm38.p6 Ensembl5115,074,367 - 115,076,872 (+)Ensembl
RefSeq Acc Id: NM_029012   ⟹   NP_083288
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395115,149,583 - 115,236,849 (+)NCBI
GRCm385115,011,524 - 115,098,790 (+)ENTREZGENE
MGSCv375115,461,533 - 115,548,799 (+)RGD
Celera5112,107,828 - 112,194,819 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017321123   ⟹   XP_017176612
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395115,149,204 - 115,236,315 (+)NCBI
GRCm385115,074,824 - 115,098,256 (+)NCBI
Sequence:
RefSeq Acc Id: NP_083288   ⟸   NM_029012
- UniProtKB: Q9CUS9 (UniProtKB/Swiss-Prot),   Q8R597 (UniProtKB/Swiss-Prot),   E9QP88 (UniProtKB/Swiss-Prot),   Q5RJH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017176612   ⟸   XM_017321123
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000031530   ⟸   ENSMUST00000031530
Ensembl Acc Id: ENSMUSP00000143889   ⟸   ENSMUST00000128590

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CUS9-F1-model_v2 AlphaFold Q9CUS9 1-384 view protein structure

Promoters
RGD ID:6887716
Promoter ID:EPDNEW_M7309
Type:multiple initiation site
Name:Sppl3_1
Description:Mus musculus signal peptide peptidase 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385115,011,552 - 115,011,612EPDNEW
RGD ID:6838408
Promoter ID:MM_KWN:43621
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000034671,   OTTMUST00000034678
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365115,460,766 - 115,461,266 (+)MPROMDB
RGD ID:6838409
Promoter ID:MM_KWN:43626
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Lung
Transcripts:OTTMUST00000034677
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365115,545,374 - 115,545,874 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1891433 AgrOrtholog
Ensembl Genes ENSMUSG00000029550 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000031530 ENTREZGENE
  ENSMUST00000031530.9 UniProtKB/Swiss-Prot
  ENSMUST00000128590.3 UniProtKB/TrEMBL
InterPro Peptidase_A22B_SPP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Preselin/SPP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:74585 UniProtKB/Swiss-Prot
MGD MGI:1891433 ENTREZGENE
NCBI Gene Sppl3 ENTREZGENE
PANTHER PTHR12174 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIGNAL PEPTIDE PEPTIDASE-LIKE 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_A22B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sppl3 PhenoGen
SMART PSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0J9YTX1_MOUSE UniProtKB/TrEMBL
  E9QP88 ENTREZGENE
  Q5RJH9 ENTREZGENE, UniProtKB/TrEMBL
  Q66L48_MOUSE UniProtKB/TrEMBL
  Q8R597 ENTREZGENE
  Q9CUS9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary E9QP88 UniProtKB/Swiss-Prot
  Q8R597 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Sppl3  signal peptide peptidase 3  Usmg3  upregulated during skeletal muscle growth 3  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 Usmg3  upregulated during skeletal muscle growth 3  Sppl3  signal peptide peptidase 3  Symbol and/or name change 5135510 APPROVED