Oosp1 (oocyte secreted protein 1)

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Gene: Oosp1 (oocyte secreted protein 1) Mus musculus

Analyze

Symbol:

Oosp1

Name:

oocyte secreted protein 1

RGD ID:

1619898

MGI Page

MGI

Description:

Acts upstream of or within blastocyst development. Predicted to be located in extracellular region. Orthologous to human OOSP1 (oocyte secreted protein 1).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

AA536827; initiate factor 3; oocyte secretory protein 1; oocyte-secreted protein 1

RGD Orthologs

Human

Rat

Bonobo

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	11,644,824 - 11,668,415 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	11,644,824 - 11,668,514 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	11,667,460 - 11,691,051 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	11,667,460 - 11,691,150 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	11,741,950 - 11,765,541 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	11,734,505 - 11,758,096 (-)	NCBI		MGSCv36	mm8
Celera	19	12,339,470 - 12,365,068 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	8.48	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (EXP)

17alpha-ethynylestradiol (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

atrazine (ISO)

cypermethrin (EXP)

diclofenac (EXP)

ibuprofen (EXP)

ochratoxin A (ISO)

titanium dioxide (EXP)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst development (IGI)

Cellular Component

extracellular region (IEA,TAS)

Molecular Function

molecular_function (ND)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

no abnormal phenotype detected (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:10725249	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11747200	PMID:12237121	PMID:12466851	PMID:12477932	PMID:15317747	PMID:15907208
PMID:16141072	PMID:16141073	PMID:21267068	PMID:21677750	PMID:24357321	PMID:32231122

Genomics

Comparative Map Data

Oosp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	11,644,824 - 11,668,415 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	11,644,824 - 11,668,514 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	11,667,460 - 11,691,051 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	11,667,460 - 11,691,150 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	11,741,950 - 11,765,541 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	11,734,505 - 11,758,096 (-)	NCBI		MGSCv36	mm8
Celera	19	12,339,470 - 12,365,068 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	8.48	NCBI

OOSP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	59,938,432 - 59,957,480 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	59,938,432 - 59,957,480 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	59,705,905 - 59,724,953 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Celera	11	57,068,680 - 57,126,568 (+)	NCBI		Celera
Cytogenetic Map	11	q12.1	NCBI
HuRef	11	56,080,215 - 56,110,512 (+)	NCBI		HuRef
CHM1_1	11	59,599,016 - 59,629,325 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	59,889,734 - 59,908,777 (+)	NCBI		T2T-CHM13v2.0

Oosp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	208,515,497 - 208,547,077 (-)	NCBI	mRatBN7.2	mRatBN7.2
Rnor_6.0	1	228,032,363 - 228,058,901 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	235,098,340 - 235,133,711 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	214,426,514 - 214,450,091 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	205,991,188 - 206,020,206 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

OOSP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	60,998,277 - 61,087,114 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	62,041,950 - 62,130,818 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	55,151,958 - 55,169,398 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

Variants

Variants in Oosp1
577 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	135
Count of miRNA genes:	123
Interacting mature miRNAs:	129
Transcripts:	ENSMUST00000048214, ENSMUST00000139158
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142302	Nstr1_m	nerve sheath tumor resistance QTL 1 (mouse)			Not determined		19	1	22371338	Mouse
1301271	Datd_m	dopamine transporter density (mouse)			Not determined		19	1	32340234	Mouse
1300923	Bits4_m	bitterness sensitivity 4 (mouse)			Not determined		19	3323216	37323348	Mouse
11039522	Tbbr4_m	Trypanosoma brucei brucei response 4 (mouse)					19	5313326	39313470	Mouse
4142161	Drinksac2_m	drink saccharin 2 (mouse)			Not determined			1	20695286	Mouse
1357819	Tgct2_m	testicular germ cell tumor 2 (mouse)			Not determined		19	3328551	20539663	Mouse
1302019	Pgia23_m	proteoglycan induced arthritis 23 (mouse)			Not determined		19	9787453	43787602	Mouse
38455997	Cdtm2_m	CD62L+ CD8 TM cells 2 (mouse)					19	9977364	19977364	Mouse
4142406	Pbctlp1_m	peripheral blood cytotoxic T lymphocyte percentage 1 (mouse)			Not determined			1	32875174	Mouse
1300776	Lfp3_m	long free running period 3 (mouse)			Not determined		19	1	20328703	Mouse
1300904	Chab5_m	cholesterol absorption 5 (mouse)			Not determined		19	1653764	35653927	Mouse
26884385	Skwq14_m	skull length QTL 14, 16 week (mouse)					19	3250000	35877400	Mouse
1301800	Faq10_m	fluctuating asymmetry QTL 10 (mouse)			Not determined		19	3323216	37323348	Mouse
1300591	Pas3_m	pulmonary adenoma susceptibility 3 (mouse)			Not determined		19	3323216	37323348	Mouse
1302126	Skull26_m	skull morphology 26 (mouse)			Not determined		19	3323216	37323348	Mouse
1301228	Iba4_m	induction of brown adipocytes 4 (mouse)			Not determined		19	9305715	43305821	Mouse

Markers in Region

RH124299

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	11,688,676 - 11,688,778	UniSTS	GRCm38
MGSCv37	19	11,763,166 - 11,763,268	UniSTS	GRCm37
Celera	19	12,362,693 - 12,362,795	UniSTS
Cytogenetic Map	19	A	UniSTS

Oosp1

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
MGSCv37	19	11,765,606 - 11,765,920	UniSTS	GRCm37
MGSCv37	19	11,765,764 - 11,766,025	UniSTS	GRCm37
Celera	19	12,365,291 - 12,365,552	UniSTS
Celera	19	12,365,133 - 12,365,447	UniSTS
cM Map	19		UniSTS

UniSTS:237894

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	11,667,699 - 11,668,363	UniSTS	GRCm38
MGSCv37	19	11,742,189 - 11,742,853	UniSTS	GRCm37
Celera	19	12,339,709 - 12,340,373	UniSTS
Cytogenetic Map	19	A	UniSTS

Oosp1

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	11,691,274 - 11,691,535	UniSTS	GRCm38
MGSCv37	19	11,765,764 - 11,766,025	UniSTS	GRCm37
Celera	19	12,365,291 - 12,365,552	UniSTS
Cytogenetic Map	19	A	UniSTS
cM Map	19		UniSTS

Oosp1

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	11,691,116 - 11,691,430	UniSTS	GRCm38
MGSCv37	19	11,765,606 - 11,765,920	UniSTS	GRCm37
Celera	19	12,365,133 - 12,365,447	UniSTS
Cytogenetic Map	19	A	UniSTS
cM Map	19		UniSTS

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB050982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB086437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC127289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF420487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK033038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK162132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC100313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000048214 ⟹ ENSMUSP00000036529

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	11,644,824 - 11,668,514 (-)	Ensembl
GRCm38.p6 Ensembl	19	11,667,460 - 11,691,150 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000139158 ⟹ ENSMUSP00000123469

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	11,645,037 - 11,668,398 (-)	Ensembl
GRCm38.p6 Ensembl	19	11,667,673 - 11,691,034 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000186557 ⟹ ENSMUSP00000139444

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	19	11,644,899 - 11,668,392 (-)	Ensembl
GRCm38.p6 Ensembl	19	11,667,535 - 11,691,028 (-)	Ensembl

RefSeq Acc Id:

NM_133353 ⟹ NP_579931

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	19	11,644,824 - 11,668,415 (-)	NCBI
GRCm38	19	11,667,460 - 11,691,051 (-)	ENTREZGENE
MGSCv37	19	11,741,950 - 11,765,541 (-)	RGD
Celera	19	12,339,470 - 12,365,068 (-)	RGD
cM Map	19		ENTREZGENE

Sequence:

show sequence

TTTCCTCTCTGGGGTTTGATCTTCAGCCTGAGCAATGAAGCCTTTCGTGGGCCTGCTGGGACTC
CTCCTGCTTCTTTCCTTTATGAAGACTTGTGCTGATGATTGGACAGCCATTAGTCTGCAATGTG
CCGACCACTGGTTCCATCTAAGGATCAGGCCTACGATATTTCACAACATTTTTATGGAACCCGA
TGAAGTGTTTTTAGGAATTGGCTGCCCTGTGACCACTACCTGGCCAAATGATACCTATGAATTT
ATCTACCGGACTTACTCCTGCGGCATTGCCAATAAAGTTCTTTGTGATGTCACTCTGCTGAAGA
CGCAACTTACATACATCTCAAAAAATGCTTCTCTACAAGCTGAGATGAGTTTGTCCTGTGTTAT
GCACAATCAGAGTCCTCATTTCTGTGAAGCAGAAAGTAGAGGAGATTTCACTGGTGATCCTCCT
GGATGGACAGAAGATATGAGGGCAAGAAGAGATGAGCAAACTGTTCCGATGGTGCAACCAAACC
TTTCAACATCAAGCGAAGATCACCATGTCTCCACGGAGCCTTGGGCCTCTGAAACGAGCAGGTC
TGAGGCTGCTGAAGTACCTAGCTTCATGGATCAAAACTTCTCGGTTTTCCATTTCTCCAGAATG
TAGATGGTCTGGTGATTTCTTATCTCCTTTTTAAAAAGATACAATTTTCAATTTTAAATAAAGT
AAAATGCGACCTTCATATATTCTCATTTTTAAAAAGGAGCTGTCCCTGCTTTTAATTGTATAAA
ATCTGATTAAAGAATAAAAATTTCCCATTAGTGCCGTGTCTAATTACTGAAGGATTAATGTGCA
TATTTTTAAGCCTAATGATCATAAATAGTTATTTTTTCTTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_579931	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI00314	(Get FASTA)	NCBI Sequence Viewer
	AAL82591	(Get FASTA)	NCBI Sequence Viewer
	BAB47553	(Get FASTA)	NCBI Sequence Viewer
	BAC11848	(Get FASTA)	NCBI Sequence Viewer
	BAC28135	(Get FASTA)	NCBI Sequence Viewer
	BAE36744	(Get FASTA)	NCBI Sequence Viewer
	EDL41437	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000036529
	ENSMUSP00000036529.3
	ENSMUSP00000123469.2
	ENSMUSP00000139444.2
GenBank Protein	Q925U0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_579931 ⟸ NM_133353
- Peptide Label:	precursor
- UniProtKB:	Q3TSD1 (UniProtKB/Swiss-Prot), Q8K4N9 (UniProtKB/Swiss-Prot), Q925U0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVT TTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAE SRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQ NFSVFHFSRM hide sequence

Ensembl Acc Id:

ENSMUSP00000123469 ⟸ ENSMUST00000139158

Ensembl Acc Id:

ENSMUSP00000139444 ⟸ ENSMUST00000186557

Ensembl Acc Id:

ENSMUSP00000036529 ⟸ ENSMUST00000048214

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q925U0-F1-model_v2	AlphaFold	Q925U0	1-202	view protein structure

Promoters

RGD ID:

13678990

Promoter ID:

EPDNEW_M23644

Type:

single initiation site

Name:

Oosp1_1

Description:

Mus musculus oocyte secreted protein 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	19	11,691,055 - 11,691,115	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2149290	AgrOrtholog
Ensembl Genes	ENSMUSG00000041857	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000048214	ENTREZGENE
	ENSMUST00000048214.9	UniProtKB/Swiss-Prot
	ENSMUST00000139158.2	UniProtKB/Swiss-Prot
	ENSMUST00000186557.2	UniProtKB/TrEMBL
InterPro	PLAC1_fam	UniProtKB/Swiss-Prot
KEGG Report	mmu:170834	UniProtKB/Swiss-Prot
MGD	MGI:2149290	ENTREZGENE
NCBI Gene	170834	ENTREZGENE
PANTHER	PTHR14380	UniProtKB/Swiss-Prot
	PTHR14380:SF3	UniProtKB/Swiss-Prot
PhenoGen	Oosp1	PhenoGen
UniProt	A0A087WNQ0_MOUSE	UniProtKB/TrEMBL
	OOSP1_MOUSE	UniProtKB/Swiss-Prot
	Q3TSD1	ENTREZGENE
	Q8K4N9	ENTREZGENE
	Q925U0	ENTREZGENE
UniProt Secondary	Q3TSD1	UniProtKB/Swiss-Prot
	Q8K4N9	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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