Tubal3 (tubulin, alpha-like 3) - Rat Genome Database

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Gene: Tubal3 (tubulin, alpha-like 3) Mus musculus
Analyze
Symbol: Tubal3
Name: tubulin, alpha-like 3
RGD ID: 1619822
MGI Page MGI
Description: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Orthologous to human TUBAL3 (tubulin alpha like 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: tubulin alpha chain-like 3
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,974,695 - 3,985,277 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,968,274 - 3,985,277 (+)EnsemblGRCm39 Ensembl
GRCm38133,924,654 - 3,935,277 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,918,274 - 3,935,277 (+)EnsemblGRCm38mm10GRCm38
MGSCv37133,923,941 - 3,934,523 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,923,941 - 3,934,522 (+)NCBIMGSCv36mm8
Celera133,911,503 - 3,922,156 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map132.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21677750   PMID:21873635   PMID:27113764   PMID:28378742  
PMID:30457570   PMID:32581705   PMID:32968282   PMID:38355793   PMID:38786026  


Genomics

Comparative Map Data
Tubal3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,974,695 - 3,985,277 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,968,274 - 3,985,277 (+)EnsemblGRCm39 Ensembl
GRCm38133,924,654 - 3,935,277 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,918,274 - 3,935,277 (+)EnsemblGRCm38mm10GRCm38
MGSCv37133,923,941 - 3,934,523 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,923,941 - 3,934,522 (+)NCBIMGSCv36mm8
Celera133,911,503 - 3,922,156 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map132.19NCBI
TUBAL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38105,393,101 - 5,404,828 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl105,393,101 - 5,404,828 (-)EnsemblGRCh38hg38GRCh38
GRCh37105,435,064 - 5,446,791 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36105,425,061 - 5,436,795 (-)NCBINCBI36Build 36hg18NCBI36
Build 34105,425,061 - 5,436,793NCBI
Celera105,365,751 - 5,377,481 (-)NCBICelera
Cytogenetic Map10p15.1NCBI
HuRef105,364,310 - 5,376,040 (-)NCBIHuRef
CHM1_1105,435,075 - 5,446,807 (-)NCBICHM1_1
T2T-CHM13v2.0105,396,486 - 5,408,211 (-)NCBIT2T-CHM13v2.0
Tubal3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81771,233,194 - 71,245,297 (-)NCBIGRCr8
mRatBN7.21766,323,733 - 66,332,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1766,323,733 - 66,335,355 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1769,797,730 - 69,806,391 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01773,626,559 - 73,635,216 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01767,669,558 - 67,678,215 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01769,974,272 - 69,982,957 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1769,974,272 - 69,982,957 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01771,677,393 - 71,689,465 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41777,496,632 - 77,505,317 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11777,507,464 - 77,519,110 (-)NCBI
Celera1765,829,390 - 65,838,075 (-)NCBICelera
Cytogenetic Map17q12.2NCBI
TUBAL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2817,949,991 - 18,002,800 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11017,955,312 - 18,008,123 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0105,438,493 - 5,450,210 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1105,424,804 - 5,436,517 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl105,424,484 - 5,436,529 (-)Ensemblpanpan1.1panPan2
TUBAL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1230,523,678 - 30,531,909 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl230,523,652 - 30,532,263 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha227,553,248 - 27,561,453 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0230,904,138 - 30,912,375 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl230,904,136 - 30,912,716 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1228,000,262 - 28,008,460 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0228,837,369 - 28,845,572 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,554,952 - 29,563,189 (+)NCBIUU_Cfam_GSD_1.0
Tubal3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934432,891,247 - 32,906,304 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364849,062,478 - 9,072,988 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364849,066,097 - 9,073,049 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TUBAL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1065,476,227 - 65,488,116 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11065,476,215 - 65,487,334 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21071,595,275 - 71,607,484 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TUBAL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.195,515,163 - 5,527,043 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605110,769,619 - 10,781,432 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tubal3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624796115,091 - 123,436 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624796102,139 - 123,446 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tubal3
207 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:512
Count of miRNA genes:372
Interacting mature miRNAs:416
Transcripts:ENSMUST00000021639
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10045625Heal23_mwound healing/regeneration 23 (mouse)Not determined13347761237477820Mouse
1301890Adip7_madiposity 7 (mouse)Not determined13123454672Mouse
10045624Heal24_mwound healing/regeneration (mouse)Not determined13347761237477820Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1301255Cd4ts6_mCD4 T cell subset 6 (mouse)Not determined1316854534168684Mouse
1301367Twq1_mtestis weight QTL 1 (mouse)Not determined13361551237615672Mouse
1301733Heal3_mwound healing/regeneration 3 (mouse)Not determined13368020037680343Mouse
1301227Skull19_mskull morphology 19 (mouse)Not determined13123454672Mouse
10449140Eosn2_meosinophil differential 2 (mouse)1322131134221311Mouse
1301455Bmd3_mbone mineral density 3 (mouse)Not determined13347761237477820Mouse
1301661Tshp13_mtooth shape 13 (mouse)Not determined13123454672Mouse
15039338Nmrs34_mNAFLD-associated magnetic resonance shift 34 (mouse)1322131134221311Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000021639   ⟹   ENSMUSP00000021639
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl133,974,695 - 3,985,277 (+)Ensembl
GRCm38.p6 Ensembl133,924,695 - 3,935,277 (+)Ensembl
Ensembl Acc Id: ENSMUST00000223035
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl133,968,274 - 3,983,506 (+)Ensembl
GRCm38.p6 Ensembl133,918,274 - 3,933,506 (+)Ensembl
RefSeq Acc Id: NM_001033879   ⟹   NP_001029051
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39133,974,695 - 3,985,277 (+)NCBI
GRCm38133,924,695 - 3,935,277 (+)NCBI
MGSCv37133,923,941 - 3,934,523 (+)RGD
Celera133,911,503 - 3,922,156 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001426388   ⟹   NP_001413317
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39133,974,695 - 3,983,725 (+)NCBI
RefSeq Acc Id: NM_001426389   ⟹   NP_001413318
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39133,974,695 - 3,983,725 (+)NCBI
RefSeq Acc Id: NM_001426391   ⟹   NP_001413320
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39133,974,695 - 3,983,725 (+)NCBI
RefSeq Acc Id: XM_006516479   ⟹   XP_006516542
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39133,974,714 - 3,983,730 (+)NCBI
GRCm38133,924,654 - 3,933,730 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001029051   ⟸   NM_001033879
- Peptide Label: isoform 1
- UniProtKB: B9EJS3 (UniProtKB/Swiss-Prot),   Q3UX10 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006516542   ⟸   XM_006516479
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000021639   ⟸   ENSMUST00000021639
RefSeq Acc Id: NP_001413317   ⟸   NM_001426388
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001413318   ⟸   NM_001426389
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001413320   ⟸   NM_001426391
- Peptide Label: isoform 4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UX10-F1-model_v2 AlphaFold Q3UX10 1-446 view protein structure

Promoters
RGD ID:8679516
Promoter ID:EPDNEW_M17789
Type:initiation region
Name:Tubal3_1
Description:Mus musculus tubulin, alpha-like 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38133,924,695 - 3,924,755EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3588215 AgrOrtholog
Ensembl Genes ENSMUSG00000021216 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000021639 ENTREZGENE
  ENSMUST00000021639.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.600 UniProtKB/Swiss-Prot
  3.30.1330.20 UniProtKB/Swiss-Prot
  3.40.50.1440 UniProtKB/Swiss-Prot
InterPro Alpha_tubulin UniProtKB/Swiss-Prot
  Tub_FtsZ_C UniProtKB/Swiss-Prot
  Tubulin UniProtKB/Swiss-Prot
  Tubulin/FtsZ_2-layer-sand-dom UniProtKB/Swiss-Prot
  Tubulin/FtsZ_C_sf UniProtKB/Swiss-Prot
  Tubulin/FtsZ_GTPase_sf UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
  Tubulin_CS UniProtKB/Swiss-Prot
  Tubulin_FtsZ_GTPase UniProtKB/Swiss-Prot
KEGG Report mmu:238463 UniProtKB/Swiss-Prot
MGD MGI:3588215 ENTREZGENE
NCBI Gene 238463 ENTREZGENE
PANTHER PTHR11588 UniProtKB/Swiss-Prot
  TUBULIN ALPHA CHAIN-LIKE 3 UniProtKB/Swiss-Prot
Pfam Tubulin UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
PhenoGen Tubal3 PhenoGen
PRINTS ALPHATUBULIN UniProtKB/Swiss-Prot
  TUBULIN UniProtKB/Swiss-Prot
PROSITE TUBULIN UniProtKB/Swiss-Prot
SMART Tubulin UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52490 UniProtKB/Swiss-Prot
  SSF55307 UniProtKB/Swiss-Prot
UniProt B9EJS3 ENTREZGENE
  Q3UX10 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B9EJS3 UniProtKB/Swiss-Prot