Slc25a48 (solute carrier family 25, member 48) - Rat Genome Database

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Gene: Slc25a48 (solute carrier family 25, member 48) Mus musculus
Analyze
Symbol: Slc25a48
Name: solute carrier family 25, member 48
RGD ID: 1618792
MGI Page MGI
Description: Predicted to enable transmembrane transporter activity. Located in mitochondrion. Orthologous to human SLC25A48 (solute carrier family 25 member 48).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AU042651; E230025K15; expressed sequence AU042651; MGC130189; MGC130190; mitochondrial carrier protein-like; putative mitochondrial carrier protein FLJ44862 homolog; solute carrier family 25 member 48
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391356,585,774 - 56,620,180 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1356,586,168 - 56,622,052 (+)EnsemblGRCm39 Ensembl
GRCm381356,437,960 - 56,472,367 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1356,438,355 - 56,474,239 (+)EnsemblGRCm38mm10GRCm38
MGSCv371356,539,716 - 56,573,724 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361356,447,977 - 56,481,943 (+)NCBIMGSCv36mm8
Celera1357,498,851 - 57,536,050 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:17015433   PMID:18614015   PMID:21677750  
PMID:21873635   PMID:38355793   PMID:39111307  


Genomics

Comparative Map Data
Slc25a48
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391356,585,774 - 56,620,180 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1356,586,168 - 56,622,052 (+)EnsemblGRCm39 Ensembl
GRCm381356,437,960 - 56,472,367 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1356,438,355 - 56,474,239 (+)EnsemblGRCm38mm10GRCm38
MGSCv371356,539,716 - 56,573,724 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361356,447,977 - 56,481,943 (+)NCBIMGSCv36mm8
Celera1357,498,851 - 57,536,050 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
SLC25A48
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385135,579,172 - 135,888,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5135,476,913 - 135,889,770 (+)EnsemblGRCh38hg38GRCh38
GRCh375134,914,862 - 135,224,326 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365135,198,264 - 135,236,335 (+)NCBINCBI36Build 36hg18NCBI36
Celera5131,295,101 - 131,349,055 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5130,358,467 - 130,412,795 (+)NCBIHuRef
CHM1_15134,602,986 - 134,656,957 (+)NCBICHM1_1
T2T-CHM13v2.05136,106,315 - 136,411,134 (+)NCBIT2T-CHM13v2.0
Slc25a48
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,113,134 - 8,172,376 (-)NCBIGRCr8
mRatBN7.2178,119,964 - 8,161,293 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,121,175 - 8,160,748 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0178,567,014 - 8,608,213 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,570,472 - 8,607,494 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01710,741,365 - 10,782,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera178,212,422 - 8,242,778 (-)NCBICelera
Cytogenetic Map17p14NCBI
Slc25a48
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540830,901,124 - 30,940,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540830,775,521 - 30,940,335 (+)NCBIChiLan1.0ChiLan1.0
SLC25A48
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24131,123,332 - 131,177,313 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15129,262,892 - 129,316,873 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05131,227,723 - 131,281,708 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15137,108,442 - 137,421,754 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5137,367,729 - 137,421,754 (+)Ensemblpanpan1.1panPan2
SLC25A48
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11123,754,223 - 23,808,172 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1123,761,858 - 23,852,384 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1122,509,857 - 22,562,237 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01124,578,420 - 24,630,593 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1124,578,231 - 24,669,380 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11123,265,817 - 23,306,502 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01123,131,538 - 23,183,916 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01123,781,666 - 23,834,067 (+)NCBIUU_Cfam_GSD_1.0
Slc25a48
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213123,899,751 - 123,940,624 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365972,925,021 - 2,962,437 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365972,924,814 - 2,965,529 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A48
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2137,986,828 - 138,035,578 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12137,979,811 - 138,035,582 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22143,578,973 - 143,634,938 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A48
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12338,580,380 - 38,633,232 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603439,275,845 - 39,326,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a48
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473311,237,609 - 11,280,774 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473311,240,090 - 11,280,573 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc25a48
1092 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:717
Count of miRNA genes:473
Interacting mature miRNAs:537
Transcripts:ENSMUST00000021971
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132047761259821605Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132791846961918560Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2583652959836529Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132821737962217515Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132821044262210544Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132821737962217515Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse

Markers in Region
AU042651  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381356,472,115 - 56,472,276UniSTSGRCm38
MGSCv371356,573,476 - 56,573,637UniSTSGRCm37
Celera1357,535,802 - 57,535,963UniSTS
Cytogenetic Map13B1UniSTS
Whitehead/MRC_RH13578.74UniSTS
RH125293  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381356,472,795 - 56,472,886UniSTSGRCm38
MGSCv371356,574,156 - 56,574,247UniSTSGRCm37
Celera1357,536,384 - 57,536,475UniSTS
Cytogenetic Map13B1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000021971   ⟹   ENSMUSP00000021971
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,586,168 - 56,622,052 (+)Ensembl
GRCm38.p6 Ensembl1356,438,355 - 56,474,239 (+)Ensembl
RefSeq Acc Id: NM_177809   ⟹   NP_808477
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,586,168 - 56,620,176 (+)NCBI
GRCm381356,438,355 - 56,472,363 (+)NCBI
MGSCv371356,539,716 - 56,573,724 (+)RGD
Celera1357,498,851 - 57,536,050 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006517278   ⟹   XP_006517341
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,585,778 - 56,620,180 (+)NCBI
GRCm381356,437,965 - 56,472,367 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011244532   ⟹   XP_011242834
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,585,778 - 56,619,720 (+)NCBI
GRCm381356,437,965 - 56,471,907 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030247304   ⟹   XP_030103164
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,585,774 - 56,620,180 (+)NCBI
GRCm381356,437,960 - 56,472,367 (+)NCBI
Sequence:
RefSeq Acc Id: NP_808477   ⟸   NM_177809
- UniProtKB: Q8BW66 (UniProtKB/Swiss-Prot),   Q3KNJ4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006517341   ⟸   XM_006517278
- Peptide Label: isoform X1
- UniProtKB: Q8BW66 (UniProtKB/Swiss-Prot),   Q3KNJ4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242834   ⟸   XM_011244532
- Peptide Label: isoform X1
- UniProtKB: Q8BW66 (UniProtKB/Swiss-Prot),   Q3KNJ4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030103164   ⟸   XM_030247304
- Peptide Label: isoform X2
Ensembl Acc Id: ENSMUSP00000021971   ⟸   ENSMUST00000021971

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BW66-F1-model_v2 AlphaFold Q8BW66 1-306 view protein structure

Promoters
RGD ID:8680582
Promoter ID:EPDNEW_M18281
Type:initiation region
Name:Slc25a48_1
Description:Mus musculus solute carrier family 25, member 48 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381356,438,362 - 56,438,422EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2145373 AgrOrtholog
Ensembl Genes ENSMUSG00000021509 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000021971 ENTREZGENE
  ENSMUST00000021971.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.50.40.10 UniProtKB/Swiss-Prot
InterPro Mitochondrial_Carrier UniProtKB/Swiss-Prot
  Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:328258 UniProtKB/Swiss-Prot
MGD MGI:2145373 ENTREZGENE
NCBI Gene Slc25a48 ENTREZGENE
PANTHER MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED UniProtKB/Swiss-Prot
  SOLUTE CARRIER FAMILY 25 MEMBER 48 UniProtKB/Swiss-Prot
Pfam Mito_carr UniProtKB/Swiss-Prot
PhenoGen Slc25a48 PhenoGen
PROSITE SOLCAR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot
UniProt Q3KNJ4 ENTREZGENE
  Q8BW66 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3KNJ4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Slc25a48  solute carrier family 25, member 48  AU042651  expressed sequence AU042651  Symbol and/or name change 5135510 APPROVED
2024-08-21 AU042651  expressed sequence AU042651  Slc25a48  solute carrier family 25, member 48  Symbol and/or name change 5135510 APPROVED
2011-07-27 Slc25a48  solute carrier family 25, member 48  AU042651  expressed sequence AU042651  Symbol and/or name change 5135510 APPROVED