Greb1 (gene regulated by estrogen in breast cancer protein) - Rat Genome Database

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Gene: Greb1 (gene regulated by estrogen in breast cancer protein) Mus musculus
Analyze
Symbol: Greb1
Name: gene regulated by estrogen in breast cancer protein
RGD ID: 1618016
MGI Page MGI
Description: Predicted to be involved in morphogenesis of an epithelium. Predicted to be located in membrane. Is expressed in several structures, including central nervous system; genitourinary system; incisor; retina nuclear layer; and tail unsegmented mesenchyme. Orthologous to human GREB1 (growth regulating estrogen receptor binding 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 5730583K22Rik; 9130004E13; AF180470; AU023194; Kiaa0575; mKIAA0575
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391216,720,616 - 16,851,395 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1216,720,616 - 16,850,887 (-)EnsemblGRCm39 Ensembl
GRCm381216,670,615 - 16,801,394 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1216,670,615 - 16,800,886 (-)EnsemblGRCm38mm10GRCm38
MGSCv371216,677,421 - 16,807,692 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361216,764,663 - 16,851,042 (-)NCBIMGSCv36mm8
MGSCv361216,697,105 - 16,782,721 (-)NCBIMGSCv36mm8
Celera1216,991,168 - 17,123,379 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map128.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-linalyl acetate  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,8-cineole  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3'-diindolylmethane  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-terpineol  (ISO)
4-tert-Octylphenol  (ISO)
afimoxifene  (EXP,ISO)
aflatoxin B1  (ISO)
alpha-terpineol  (ISO)
apigenin  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
chlordecone  (EXP,ISO)
chrysene  (EXP)
chrysin  (ISO)
cisplatin  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
cyproterone  (ISO)
cyproterone acetate  (ISO)
daidzein  (ISO)
dapsone  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
enzalutamide  (ISO)
ethisterone  (ISO)
ethylparaben  (ISO)
fenvalerate  (ISO)
fipronil  (ISO)
flutamide  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gamma-terpinene  (ISO)
genistein  (ISO)
glyphosate  (ISO)
hexestrol  (ISO)
Isobutylparaben  (ISO)
ivermectin  (ISO)
kaempferol  (ISO)
ketoconazole  (ISO)
lead diacetate  (EXP)
levonorgestrel  (ISO)
limonene  (ISO)
linalool  (ISO)
linalyl acetate  (ISO)
lipopolysaccharide  (ISO)
Lynestrenol  (ISO)
megestrol acetate  (ISO)
mestranol  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methyltestosterone  (ISO)
mifepristone  (ISO)
molibresib  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nandrolone  (ISO)
nickel atom  (ISO)
nilutamide  (ISO)
norethisterone  (ISO)
Norethynodrel  (ISO)
O-methyleugenol  (ISO)
oxybenzone  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
picoxystrobin  (ISO)
pregnenolone  (ISO)
progesterone  (EXP,ISO)
propiconazole  (EXP)
raloxifene  (EXP,ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
spironolactone  (ISO)
tamoxifen  (EXP)
tea tree oil  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
testosterone undecanoate  (ISO)
tetraphene  (EXP)
titanium dioxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (EXP,ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7671812   PMID:8889548   PMID:10349636   PMID:10644441   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11103799   PMID:11217851   PMID:12466851   PMID:12477932  
PMID:15226823   PMID:16075367   PMID:16141072   PMID:16141073   PMID:18287559   PMID:19501082   PMID:21267068   PMID:21491433   PMID:21491542   PMID:21677750   PMID:21873635   PMID:23961710  
PMID:24194600   PMID:27626380   PMID:28911214   PMID:29100091   PMID:29555813   PMID:29955957   PMID:31462641   PMID:31988092   PMID:33731348   PMID:37516458   PMID:37528140   PMID:38355793  
PMID:38431630  


Genomics

Comparative Map Data
Greb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391216,720,616 - 16,851,395 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1216,720,616 - 16,850,887 (-)EnsemblGRCm39 Ensembl
GRCm381216,670,615 - 16,801,394 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1216,670,615 - 16,800,886 (-)EnsemblGRCm38mm10GRCm38
MGSCv371216,677,421 - 16,807,692 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361216,764,663 - 16,851,042 (-)NCBIMGSCv36mm8
MGSCv361216,697,105 - 16,782,721 (-)NCBIMGSCv36mm8
Celera1216,991,168 - 17,123,379 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map128.0NCBI
GREB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38211,482,888 - 11,642,788 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl211,482,341 - 11,642,788 (+)EnsemblGRCh38hg38GRCh38
GRCh37211,674,171 - 11,782,914 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36211,591,693 - 11,700,363 (+)NCBINCBI36Build 36hg18NCBI36
Celera211,591,030 - 11,699,842 (+)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef211,524,429 - 11,634,440 (+)NCBIHuRef
CHM1_1211,603,825 - 11,712,536 (+)NCBICHM1_1
T2T-CHM13v2.0211,514,740 - 11,675,937 (+)NCBIT2T-CHM13v2.0
Greb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8645,169,289 - 45,321,973 (-)NCBIGRCr8
mRatBN7.2639,440,522 - 39,562,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl639,440,504 - 39,581,633 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0641,932,941 - 42,002,770 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl641,932,244 - 42,002,819 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0651,661,849 - 51,735,066 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4640,356,449 - 40,406,966 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera638,750,684 - 38,822,218 (-)NCBICelera
Cytogenetic Map6q16NCBI
Greb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554876,062,326 - 6,112,856 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554876,032,774 - 6,112,715 (+)NCBIChiLan1.0ChiLan1.0
GREB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212114,887,051 - 115,052,191 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A114,891,023 - 115,056,110 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A11,467,884 - 11,629,834 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A11,690,252 - 11,776,480 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A11,690,475 - 11,774,155 (+)Ensemblpanpan1.1panPan2
GREB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1178,250,941 - 8,327,398 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl178,252,134 - 8,325,886 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha178,168,172 - 8,258,445 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0178,340,333 - 8,430,410 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl178,339,665 - 8,429,548 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1178,225,077 - 8,315,326 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0178,228,411 - 8,318,693 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0178,247,815 - 8,338,321 (+)NCBIUU_Cfam_GSD_1.0
Greb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629252,637,359 - 52,760,217 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365327,451,348 - 7,515,259 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365327,392,705 - 7,515,242 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GREB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3125,099,935 - 125,171,036 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13125,099,352 - 125,233,965 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23133,942,984 - 133,972,487 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103220800
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11495,967,736 - 96,174,324 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1495,967,699 - 96,019,165 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604516,298,085 - 16,344,537 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Greb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248654,318,920 - 4,366,976 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248654,317,592 - 4,367,615 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Greb1
4656 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2285
Count of miRNA genes:767
Interacting mature miRNAs:962
Transcripts:ENSMUST00000048064, ENSMUST00000159044, ENSMUST00000159120, ENSMUST00000159573, ENSMUST00000160347, ENSMUST00000160575, ENSMUST00000160627, ENSMUST00000160755, ENSMUST00000160851, ENSMUST00000161036, ENSMUST00000161998, ENSMUST00000162112
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301393Dyscalc3_mdystrophic cardiac calcinosis 3 (mouse)Not determined12122418579Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130433078Mouse
4141436Chldq7_mcholesterol and HDL QTL 7 (mouse)Not determined12127920733Mouse
1301655Bmd12_mbone mineral density 12 (mouse)Not determined12124662697Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133430339Mouse
1301143Skull17_mskull morphology 17 (mouse)Not determined12122418579Mouse
1301723Fcsa7_mfemoral cross-sectional area 7 (mouse)Not determined12949100443491112Mouse
11039525Tbbr2_mTrypanosoma brucei brucei response 2 (mouse)12122418579Mouse
4141296Femwf9_mfemur work to failure 9 (mouse)Not determined127920733Mouse
10043977Obq34_mobesity QTL 34 (mouse)Not determined121514733149147331Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
12792982Fbmd4_mfemoral bone mineral density 4, females only (mouse)121004319424365136Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
1357519Vtbt12_mvertebral trabecular bone trait 12 (mouse)Not determined12124662697Mouse
10402496Lmr22_mleishmaniasis resistance 22 (mouse)Not determined12122418579Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
26884410Bzwq15_mbi-zygomatic width QTL 15, 16 week (mouse)12365000029749999Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1234013434340302Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
13524843Ppiq8_mprepulse inhibition QTL 8 (mouse)121104319450945796Mouse
26884413Bzwq9_mbi-zygomatic width QTL 9, 10 week (mouse)121615000147746783Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12805000040049999Mouse
4141516slwr_mslowlearner (mouse)Not determined1239247546392614Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132758756Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12772315841723301Mouse
14746972Manh72_mmandible shape 72 (mouse)121061528144615281Mouse
1301037Cd4ts5_mCD4 T cell subset 5 (mouse)Not determined12835244442352581Mouse
10401249Bglu15_mblood glucose level 15 (mouse)Not determined121062064244620809Mouse

Markers in Region
AU023194  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381216,670,859 - 16,670,992UniSTSGRCm38
MGSCv371216,677,665 - 16,677,798UniSTSGRCm37
Celera1216,991,413 - 16,991,546UniSTS
Cytogenetic Map12A1.1UniSTS
Whitehead/MRC_RH12180.2UniSTS
D12Mit269  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381216,749,234 - 16,749,351UniSTSGRCm38
MGSCv371216,756,040 - 16,756,157UniSTSGRCm37
Celera1217,070,167 - 17,070,290UniSTS
Cytogenetic Map12A1.1UniSTS
cM Map126.0UniSTS
Whitehead Genetic125.5UniSTS
Whitehead/MRC_RH12180.2UniSTS
C5T7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381216,757,948 - 16,758,171UniSTSGRCm38
MGSCv371216,764,754 - 16,764,977UniSTSGRCm37
Celera1217,078,798 - 17,078,992UniSTS
Cytogenetic Map12A1.1UniSTS
cM Map12 UniSTS
UniSTS:236812  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381216,670,694 - 16,670,908UniSTSGRCm38
MGSCv371216,677,500 - 16,677,714UniSTSGRCm37
Celera1216,991,247 - 16,991,462UniSTS
Cytogenetic Map12A1.1UniSTS
UniSTS:236813  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381216,671,867 - 16,672,002UniSTSGRCm38
MGSCv371216,678,673 - 16,678,808UniSTSGRCm37
Celera1216,992,424 - 16,992,559UniSTS
Cytogenetic Map12A1.1UniSTS
D12Mit184  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381216,757,496 - 16,757,624UniSTSGRCm38
MGSCv371216,764,302 - 16,764,430UniSTSGRCm37
Celera1217,078,372 - 17,078,474UniSTS
Cytogenetic Map12A1.1UniSTS
cM Map126.0UniSTS
Whitehead Genetic125.5UniSTS
Whitehead_YAC12 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001252071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_015764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004937504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_381189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_381190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_381191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_872413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB093248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC157352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF180470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC160931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM932811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ098754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ099922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN533010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN536594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000048064   ⟹   ENSMUSP00000044454
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,720,616 - 16,807,242 (-)Ensembl
GRCm38.p6 Ensembl1216,670,615 - 16,757,241 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159044
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,756,140 - 16,758,455 (-)Ensembl
GRCm38.p6 Ensembl1216,706,139 - 16,708,454 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159120   ⟹   ENSMUSP00000125339
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,722,080 - 16,807,196 (-)Ensembl
GRCm38.p6 Ensembl1216,672,079 - 16,757,195 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159573
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,773,178 - 16,790,129 (-)Ensembl
GRCm38.p6 Ensembl1216,723,177 - 16,740,128 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160347   ⟹   ENSMUSP00000124897
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,756,151 - 16,758,595 (-)Ensembl
GRCm38.p6 Ensembl1216,706,150 - 16,708,594 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160575
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,752,367 - 16,758,024 (-)Ensembl
GRCm38.p6 Ensembl1216,702,366 - 16,708,023 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160627   ⟹   ENSMUSP00000124922
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,757,887 - 16,761,774 (-)Ensembl
GRCm38.p6 Ensembl1216,707,886 - 16,711,773 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160755
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,731,945 - 16,740,803 (-)Ensembl
GRCm38.p6 Ensembl1216,681,944 - 16,690,802 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160851
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,723,810 - 16,725,041 (-)Ensembl
GRCm38.p6 Ensembl1216,673,809 - 16,675,040 (-)Ensembl
Ensembl Acc Id: ENSMUST00000161036
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,740,532 - 16,790,255 (-)Ensembl
GRCm38.p6 Ensembl1216,690,531 - 16,740,254 (-)Ensembl
Ensembl Acc Id: ENSMUST00000161998   ⟹   ENSMUSP00000124275
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,783,279 - 16,850,887 (-)Ensembl
GRCm38.p6 Ensembl1216,733,278 - 16,800,886 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162112   ⟹   ENSMUSP00000124348
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1216,720,616 - 16,850,685 (-)Ensembl
GRCm38.p6 Ensembl1216,670,615 - 16,800,684 (-)Ensembl
RefSeq Acc Id: NM_001252071   ⟹   NP_001239000
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,807,240 (-)NCBI
GRCm381216,670,615 - 16,757,239 (-)NCBI
Celera1216,991,168 - 17,123,379 (-)ENTREZGENE
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_015764   ⟹   NP_056579
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,850,887 (-)NCBI
GRCm381216,670,615 - 16,800,886 (-)NCBI
MGSCv371216,677,421 - 16,807,692 (-)RGD
Celera1216,991,168 - 17,123,379 (-)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006515093   ⟹   XP_006515156
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,851,038 (-)NCBI
GRCm381216,670,615 - 16,801,038 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515094   ⟹   XP_006515157
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,850,610 (-)NCBI
GRCm381216,670,615 - 16,800,609 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515095   ⟹   XP_006515158
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,803,336 (-)NCBI
GRCm381216,670,615 - 16,753,335 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515096   ⟹   XP_006515159
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,851,038 (-)NCBI
GRCm381216,670,615 - 16,801,038 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515097   ⟹   XP_006515160
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,850,610 (-)NCBI
GRCm381216,670,615 - 16,800,609 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515099   ⟹   XP_006515162
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,851,038 (-)NCBI
GRCm381216,670,615 - 16,801,038 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515100   ⟹   XP_006515163
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,851,038 (-)NCBI
GRCm381216,670,615 - 16,801,038 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515101   ⟹   XP_006515164
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,851,039 (-)NCBI
GRCm381216,672,443 - 16,801,038 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515103   ⟹   XP_006515166
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,756,188 - 16,851,395 (-)NCBI
GRCm381216,706,187 - 16,801,394 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515104   ⟹   XP_006515167
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,756,188 - 16,851,395 (-)NCBI
GRCm381216,706,187 - 16,801,394 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515105   ⟹   XP_006515168
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,756,146 - 16,851,395 (-)NCBI
GRCm381216,706,145 - 16,801,394 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515106   ⟹   XP_006515169
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,756,146 - 16,851,395 (-)NCBI
GRCm381216,706,145 - 16,801,394 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006515107   ⟹   XP_006515170
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,756,146 - 16,851,395 (-)NCBI
GRCm381216,706,145 - 16,801,394 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246728   ⟹   XP_030102588
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,760,399 (-)NCBI
GRCm381216,670,615 - 16,710,398 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004937504
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,851,041 (-)NCBI
Sequence:
RefSeq Acc Id: XR_381189
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,720,616 - 16,851,041 (-)NCBI
GRCm381216,670,615 - 16,801,041 (-)NCBI
Sequence:
RefSeq Acc Id: XR_381190
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,756,135 - 16,851,394 (-)NCBI
GRCm381216,706,134 - 16,801,393 (-)NCBI
Sequence:
RefSeq Acc Id: XR_381191
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,756,151 - 16,851,394 (-)NCBI
GRCm381216,706,150 - 16,801,393 (-)NCBI
Sequence:
RefSeq Acc Id: XR_872413
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391216,732,261 - 16,851,380 (-)NCBI
GRCm381216,682,260 - 16,801,378 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001239000 (Get FASTA)   NCBI Sequence Viewer  
  NP_056579 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515156 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515157 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515158 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515159 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515160 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515162 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515163 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515164 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515166 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515167 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515168 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515169 (Get FASTA)   NCBI Sequence Viewer  
  XP_006515170 (Get FASTA)   NCBI Sequence Viewer  
  XP_030102588 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF44295 (Get FASTA)   NCBI Sequence Viewer  
  BAC28368 (Get FASTA)   NCBI Sequence Viewer  
  BAC41432 (Get FASTA)   NCBI Sequence Viewer  
  BAE27854 (Get FASTA)   NCBI Sequence Viewer  
  EDK98478 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000044454
  ENSMUSP00000044454.10
  ENSMUSP00000124275.2
  ENSMUSP00000124348
  ENSMUSP00000124348.2
  ENSMUSP00000124897.2
  ENSMUSP00000124922.2
  ENSMUSP00000125339
  ENSMUSP00000125339.2
GenBank Protein Q3UHK3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_056579   ⟸   NM_015764
- Peptide Label: isoform 1
- UniProtKB: Q9JLG7 (UniProtKB/Swiss-Prot),   Q8CHE7 (UniProtKB/Swiss-Prot),   Q8BZT6 (UniProtKB/Swiss-Prot),   Q3UHK3 (UniProtKB/Swiss-Prot),   E0CYB3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001239000   ⟸   NM_001252071
- Peptide Label: isoform 2
- UniProtKB: E0CXG4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515159   ⟸   XM_006515096
- Peptide Label: isoform X1
- UniProtKB: Q9JLG7 (UniProtKB/Swiss-Prot),   Q8CHE7 (UniProtKB/Swiss-Prot),   Q8BZT6 (UniProtKB/Swiss-Prot),   Q3UHK3 (UniProtKB/Swiss-Prot),   E0CYB3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006515163   ⟸   XM_006515100
- Peptide Label: isoform X3
- UniProtKB: E0CXG4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515162   ⟸   XM_006515099
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006515156   ⟸   XM_006515093
- Peptide Label: isoform X1
- UniProtKB: Q9JLG7 (UniProtKB/Swiss-Prot),   Q8CHE7 (UniProtKB/Swiss-Prot),   Q8BZT6 (UniProtKB/Swiss-Prot),   Q3UHK3 (UniProtKB/Swiss-Prot),   E0CYB3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006515160   ⟸   XM_006515097
- Peptide Label: isoform X1
- UniProtKB: Q9JLG7 (UniProtKB/Swiss-Prot),   Q8CHE7 (UniProtKB/Swiss-Prot),   Q8BZT6 (UniProtKB/Swiss-Prot),   Q3UHK3 (UniProtKB/Swiss-Prot),   E0CYB3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006515157   ⟸   XM_006515094
- Peptide Label: isoform X1
- UniProtKB: Q9JLG7 (UniProtKB/Swiss-Prot),   Q8CHE7 (UniProtKB/Swiss-Prot),   Q8BZT6 (UniProtKB/Swiss-Prot),   Q3UHK3 (UniProtKB/Swiss-Prot),   E0CYB3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006515158   ⟸   XM_006515095
- Peptide Label: isoform X1
- UniProtKB: Q8CHE7 (UniProtKB/Swiss-Prot),   Q8BZT6 (UniProtKB/Swiss-Prot),   Q3UHK3 (UniProtKB/Swiss-Prot),   E0CYB3 (UniProtKB/Swiss-Prot),   Q9JLG7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006515164   ⟸   XM_006515101
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006515170   ⟸   XM_006515107
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_006515169   ⟸   XM_006515106
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006515168   ⟸   XM_006515105
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006515167   ⟸   XM_006515104
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006515166   ⟸   XM_006515103
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_030102588   ⟸   XM_030246728
- Peptide Label: isoform X5
Ensembl Acc Id: ENSMUSP00000125339   ⟸   ENSMUST00000159120
Ensembl Acc Id: ENSMUSP00000044454   ⟸   ENSMUST00000048064
Ensembl Acc Id: ENSMUSP00000124897   ⟸   ENSMUST00000160347
Ensembl Acc Id: ENSMUSP00000124922   ⟸   ENSMUST00000160627
Ensembl Acc Id: ENSMUSP00000124348   ⟸   ENSMUST00000162112
Ensembl Acc Id: ENSMUSP00000124275   ⟸   ENSMUST00000161998
Protein Domains
GREB1 N-terminal   GREB1-like C-terminal   GREB1-like circularly permuted SF2 helicase   GREB1-like second   TET-Associated Glycosyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UHK3-F1-model_v2 AlphaFold Q3UHK3 1-1954 view protein structure

Promoters
RGD ID:8677948
Promoter ID:EPDNEW_M17005
Type:initiation region
Name:Greb1_2
Description:Mus musculus gene regulated by estrogen in breast cancer protein, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M17006  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381216,740,219 - 16,740,279EPDNEW
RGD ID:8677950
Promoter ID:EPDNEW_M17006
Type:initiation region
Name:Greb1_1
Description:Mus musculus gene regulated by estrogen in breast cancer protein, transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M17005  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381216,800,959 - 16,801,019EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2149712 AgrOrtholog
Ensembl Genes ENSMUSG00000036523 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000048064 ENTREZGENE
  ENSMUST00000048064.16 UniProtKB/Swiss-Prot
  ENSMUST00000159120 ENTREZGENE
  ENSMUST00000159120.8 UniProtKB/TrEMBL
  ENSMUST00000160347.2 UniProtKB/TrEMBL
  ENSMUST00000160627.2 UniProtKB/TrEMBL
  ENSMUST00000161998.3 UniProtKB/TrEMBL
  ENSMUST00000162112 ENTREZGENE
  ENSMUST00000162112.8 UniProtKB/Swiss-Prot
InterPro GREB1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GREB1-like_2nd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GREB1-like_cpSF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GREB1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GREB1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:268527 UniProtKB/Swiss-Prot
MGD MGI:2149712 ENTREZGENE
NCBI Gene Greb1 ENTREZGENE
PANTHER PROTEIN GREB1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam cpSF2-GREB1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GREB1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GREB1_2nd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GREB1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Greb1 PhenoGen
UniProt E0CXG4 ENTREZGENE, UniProtKB/TrEMBL
  E0CYB3 ENTREZGENE
  E0CYD8_MOUSE UniProtKB/TrEMBL
  F6TVY7_MOUSE UniProtKB/TrEMBL
  F6U5E3_MOUSE UniProtKB/TrEMBL
  GREB1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8BZT6 ENTREZGENE
  Q8CHE7 ENTREZGENE
  Q9JLG7 ENTREZGENE
UniProt Secondary E0CYB3 UniProtKB/Swiss-Prot
  Q8BZT6 UniProtKB/Swiss-Prot
  Q8CHE7 UniProtKB/Swiss-Prot
  Q9JLG7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Greb1  gene regulated by estrogen in breast cancer protein  5730583K22Rik  RIKEN cDNA 5730583K22 gene  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 5730583K22Rik  RIKEN cDNA 5730583K22 gene  Greb1  gene regulated by estrogen in breast cancer protein  Symbol and/or name change 5135510 APPROVED