B3glct (beta-3-glucosyltransferase) - Rat Genome Database

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Gene: B3glct (beta-3-glucosyltransferase) Mus musculus
Analyze
Symbol: B3glct
Name: beta-3-glucosyltransferase
RGD ID: 1617946
MGI Page MGI
Description: Predicted to enable acetylglucosaminyltransferase activity. Acts upstream of or within several processes, including cilium assembly; protein secretion; and roof of mouth development. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in cornea; hyaloid vascular plexus; lens; lens vesicle; and retina. Used to study Peters plus syndrome. Human ortholog(s) of this gene implicated in Peters plus syndrome. Orthologous to human B3GLCT (beta 3-glucosyltransferase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B3ga; B3galtl; beta 1,3-galactosyltransferase-like; beta 3-glucosyltransferase; beta-1,3-glucosyltransferase; beta-3-glycosyltransferase-like; beta3Glc-T; Gm1057
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395149,601,565 - 149,686,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5149,601,695 - 149,686,064 (+)EnsemblGRCm39 Ensembl
GRCm385149,678,100 - 149,762,599 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5149,678,230 - 149,762,599 (+)EnsemblGRCm38mm10GRCm38
MGSCv375150,480,832 - 150,565,174 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365149,946,636 - 150,030,978 (+)NCBIMGSCv36mm8
Celera5147,678,917 - 147,763,679 (+)NCBICelera
Cytogenetic Map5G3NCBI
cM Map589.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16899492   PMID:17967808  
PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:27687499   PMID:30550785   PMID:31600785   PMID:33909046   PMID:36596814  


Genomics

Comparative Map Data
B3glct
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395149,601,565 - 149,686,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5149,601,695 - 149,686,064 (+)EnsemblGRCm39 Ensembl
GRCm385149,678,100 - 149,762,599 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5149,678,230 - 149,762,599 (+)EnsemblGRCm38mm10GRCm38
MGSCv375150,480,832 - 150,565,174 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365149,946,636 - 150,030,978 (+)NCBIMGSCv36mm8
Celera5147,678,917 - 147,763,679 (+)NCBICelera
Cytogenetic Map5G3NCBI
cM Map589.18NCBI
B3GLCT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381331,199,975 - 31,332,276 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1331,199,975 - 31,332,276 (+)EnsemblGRCh38hg38GRCh38
GRCh371331,774,112 - 31,906,413 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361330,672,112 - 30,804,413 (+)NCBINCBI36Build 36hg18NCBI36
Celera1312,841,849 - 12,974,020 (+)NCBICelera
Cytogenetic Map13q12.3NCBI
HuRef1312,600,539 - 12,717,555 (+)NCBIHuRef
CHM1_11331,741,727 - 31,874,040 (+)NCBICHM1_1
T2T-CHM13v2.01330,422,990 - 30,555,445 (+)NCBIT2T-CHM13v2.0
B3glct
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,291,910 - 10,383,190 (-)NCBIGRCr8
mRatBN7.2125,255,521 - 5,346,807 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl125,255,740 - 5,346,810 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx125,940,750 - 6,024,322 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0126,564,180 - 6,647,748 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0125,591,696 - 5,675,262 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0126,403,118 - 6,476,010 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl126,403,940 - 6,473,321 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0128,485,545 - 8,576,783 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4125,695,579 - 5,706,396 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera127,034,312 - 7,117,929 (-)NCBICelera
Cytogenetic Map12p11NCBI
B3glct
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543114,507,184 - 14,633,351 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543114,507,184 - 14,621,376 (-)NCBIChiLan1.0ChiLan1.0
B3GLCT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21430,782,142 - 30,907,554 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11321,888,398 - 22,012,836 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01312,475,095 - 12,601,818 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11330,913,127 - 31,038,347 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1330,927,270 - 31,035,719 (+)Ensemblpanpan1.1panPan2
B3GLCT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,815,681 - 8,938,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,817,628 - 8,939,249 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha258,858,395 - 8,981,403 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0258,920,118 - 9,043,371 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl258,910,525 - 9,043,736 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1258,817,894 - 8,942,955 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0258,825,921 - 8,950,637 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,869,284 - 8,992,465 (-)NCBIUU_Cfam_GSD_1.0
B3glct
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945169,960,358 - 170,042,161 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647225,942,662 - 26,006,288 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647225,909,994 - 25,991,800 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
B3GLCT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl117,792,368 - 7,907,049 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1117,792,160 - 7,907,052 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2117,763,470 - 7,875,165 (+)NCBISscrofa10.2Sscrofa10.2susScr3
B3GLCT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1310,058,041 - 10,178,996 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl310,059,196 - 10,179,037 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605734,188,163 - 34,309,750 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
B3glct
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247766,825,204 - 6,922,791 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247766,823,388 - 6,954,114 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in B3glct
3052 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1080
Count of miRNA genes:616
Interacting mature miRNAs:736
Transcripts:ENSMUST00000100404, ENSMUST00000159581, ENSMUST00000161388
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
13504734Ifvrq4_minfluenza virus resistance QTL 4 (mouse)5139985755151658149Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
13504735Ifvrq7_minfluenza virus resistance QTL 7 (mouse)5139509801151658149Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5133925558151758149Mouse
13504737Ifvrq5_minfluenza virus resistance QTL 5 (mouse)5139509801151658149Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000100404   ⟹   ENSMUSP00000097972
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5149,601,695 - 149,686,064 (+)Ensembl
GRCm38.p6 Ensembl5149,678,230 - 149,762,599 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201088
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5149,677,407 - 149,684,072 (+)Ensembl
GRCm38.p6 Ensembl5149,753,942 - 149,760,607 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202302
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5149,662,997 - 149,674,600 (+)Ensembl
GRCm38.p6 Ensembl5149,739,532 - 149,751,135 (+)Ensembl
RefSeq Acc Id: NM_001081204   ⟹   NP_001074673
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395149,601,695 - 149,686,064 (+)NCBI
GRCm385149,678,230 - 149,762,599 (+)NCBI
MGSCv375150,480,832 - 150,565,174 (+)RGD
Celera5147,678,917 - 147,763,679 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030254627   ⟹   XP_030110487
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395149,601,565 - 149,686,064 (+)NCBI
GRCm385149,678,100 - 149,762,599 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030254628   ⟹   XP_030110488
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395149,601,565 - 149,667,296 (+)NCBI
GRCm385149,678,100 - 149,743,148 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001074673   ⟸   NM_001081204
- Peptide Label: precursor
- UniProtKB: Q0PCR7 (UniProtKB/Swiss-Prot),   E9QMK8 (UniProtKB/Swiss-Prot),   Q149S5 (UniProtKB/Swiss-Prot),   Q8BHT6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030110487   ⟸   XM_030254627
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030110488   ⟸   XM_030254628
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000097972   ⟸   ENSMUST00000100404

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BHT6-F1-model_v2 AlphaFold Q8BHT6 1-489 view protein structure

Promoters
RGD ID:6888880
Promoter ID:EPDNEW_M7891
Type:initiation region
Name:B3glct_1
Description:Mus musculus beta-3-glucosyltransferase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385149,678,230 - 149,678,290EPDNEW
RGD ID:6837148
Promoter ID:MM_KWN:44970
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000075772
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365150,480,816 - 150,481,316 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685903 AgrOrtholog
Ensembl Genes ENSMUSG00000051950 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000100404 ENTREZGENE
  ENSMUST00000100404.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.550.50 UniProtKB/Swiss-Prot
InterPro Fringe-like UniProtKB/Swiss-Prot
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot
KEGG Report mmu:381694 UniProtKB/Swiss-Prot
MGD MGI:2685903 ENTREZGENE
NCBI Gene 381694 ENTREZGENE
PANTHER BETA-1,3-GLUCOSYLTRANSFERASE UniProtKB/Swiss-Prot
  FRINGE-RELATED UniProtKB/Swiss-Prot
Pfam Fringe UniProtKB/Swiss-Prot
PhenoGen B3glct PhenoGen
PROSITE ER_TARGET UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53448 UniProtKB/Swiss-Prot
UniProt B3GLT_MOUSE UniProtKB/Swiss-Prot
  E9QMK8 ENTREZGENE
  Q0PCR7 ENTREZGENE
  Q149S5 ENTREZGENE
  Q8BHT6 ENTREZGENE
UniProt Secondary E9QMK8 UniProtKB/Swiss-Prot
  Q0PCR7 UniProtKB/Swiss-Prot
  Q149S5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-09 B3glct  beta-3-glucosyltransferase  B3galtl  beta 1,3-galactosyltransferase-like  Symbol and/or name change 5135510 APPROVED