Calhm1 (calcium homeostasis modulator 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Calhm1 (calcium homeostasis modulator 1) Mus musculus
Analyze
Symbol: Calhm1
Name: calcium homeostasis modulator 1
RGD ID: 1617884
MGI Page MGI
Description: Enables voltage-gated calcium channel activity. Involved in ATP transport; protein heterooligomerization; and sensory perception of taste. Located in basolateral plasma membrane. Is expressed in forebrain; gut; and male reproductive gland or organ. Orthologous to human CALHM1 (calcium homeostasis modulator 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calcium homeostasis modulator protein 1; EG546729
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Calhm3  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391947,129,474 - 47,132,613 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1947,129,348 - 47,132,693 (-)EnsemblGRCm39 Ensembl
GRCm381947,141,035 - 47,144,174 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1947,140,909 - 47,144,254 (-)EnsemblGRCm38mm10GRCm38
MGSCv371947,215,525 - 47,218,664 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361947,194,346 - 47,197,485 (-)NCBIMGSCv36mm8
Celera1947,910,334 - 47,913,457 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1939.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21873635   PMID:22711817   PMID:22723178   PMID:23300080   PMID:23345406   PMID:23467090   PMID:24194600   PMID:24384370   PMID:24846212   PMID:24912134   PMID:25855639   PMID:25999473  
PMID:27066908   PMID:28148491   PMID:28202574   PMID:28597712   PMID:28734079   PMID:28751666   PMID:29681531   PMID:29739879   PMID:29768036   PMID:30804437   PMID:32229307   PMID:33199024  
PMID:34998826   PMID:37045597   PMID:38355793   PMID:38761122  


Genomics

Comparative Map Data
Calhm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391947,129,474 - 47,132,613 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1947,129,348 - 47,132,693 (-)EnsemblGRCm39 Ensembl
GRCm381947,141,035 - 47,144,174 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1947,140,909 - 47,144,254 (-)EnsemblGRCm38mm10GRCm38
MGSCv371947,215,525 - 47,218,664 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361947,194,346 - 47,197,485 (-)NCBIMGSCv36mm8
Celera1947,910,334 - 47,913,457 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1939.36NCBI
CALHM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810103,453,240 - 103,458,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10103,453,240 - 103,458,900 (-)EnsemblGRCh38hg38GRCh38
GRCh3710105,212,997 - 105,218,657 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610105,203,134 - 105,208,635 (-)NCBINCBI36Build 36hg18NCBI36
Celera1098,953,076 - 98,958,583 (-)NCBICelera
Cytogenetic Map10q24.33NCBI
HuRef1098,843,915 - 98,849,422 (-)NCBIHuRef
CHM1_110105,497,261 - 105,502,768 (-)NCBICHM1_1
T2T-CHM13v2.010104,340,546 - 104,346,206 (-)NCBIT2T-CHM13v2.0
Calhm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81255,971,606 - 255,974,325 (-)NCBIGRCr8
mRatBN7.21246,030,269 - 246,032,988 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1246,030,269 - 246,032,988 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1254,156,999 - 254,159,718 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01260,850,555 - 260,853,274 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01253,499,070 - 253,501,789 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01266,916,312 - 266,919,031 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,916,312 - 266,919,031 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01274,346,723 - 274,349,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41252,462,890 - 252,465,609 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1241,802,794 - 241,805,513 (-)NCBICelera
Cytogenetic Map1q54NCBI
Calhm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554857,102,059 - 7,105,396 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554857,102,059 - 7,105,396 (+)NCBIChiLan1.0ChiLan1.0
CALHM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28115,330,822 - 115,342,992 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110115,342,398 - 115,348,321 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010100,048,560 - 100,056,483 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110103,511,873 - 103,517,376 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10103,511,873 - 103,517,376 (-)Ensemblpanpan1.1panPan2
CALHM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12815,821,121 - 15,826,029 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2815,814,429 - 15,825,924 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2815,993,041 - 15,997,318 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02816,297,314 - 16,301,591 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2816,290,589 - 16,301,471 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12815,846,318 - 15,850,594 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02815,874,149 - 15,878,424 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02816,012,767 - 16,017,044 (-)NCBIUU_Cfam_GSD_1.0
Calhm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721331,016,885 - 31,019,778 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366002,620,110 - 2,623,003 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366002,620,110 - 2,623,003 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100157433
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14114,380,479 - 114,385,694 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1 Ensembl14114,386,878 - 114,392,258 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114114,380,467 - 114,393,845 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CALHM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1996,500,716 - 96,507,439 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl996,502,577 - 96,506,072 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604857,616,922 - 57,622,415 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Calhm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248312,681,170 - 2,683,716 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248312,681,129 - 2,685,278 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Calhm1
120 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:103
Interacting mature miRNAs:112
Transcripts:ENSMUST00000111813
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192738559461385705Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192023431454234461Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193675259761420004Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193837605061420004Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191591260749912719Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192231332653911504Mouse
1302104Lfp1_mlong free running period 1 (mouse)Not determined193918406461420004Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191591260749912719Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193395195261420004Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192542691759427005Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193014122461420004Mouse
10043896Bw21_mbody weight QTL 21 (mouse)Not determined193959606661420004Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192137870555378928Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3459678661420004Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193014123161420004Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191492301648923138Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191829516252295381Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192498843958988439Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193089788061420004Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2814034861420004Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193788298261420004Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193014123161420004Mouse
12738419Lfibq11_mliver fibrosis QTL 11 (mouse)194713257847852757Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192023431454234461Mouse
1300585Pgia12_mproteoglycan induced arthritis 12 (mouse)Not determined194258685961420004Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191829516252295381Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193299215861420004Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000111813   ⟹   ENSMUSP00000107444
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1947,129,348 - 47,132,693 (-)Ensembl
GRCm38.p6 Ensembl1947,140,909 - 47,144,254 (-)Ensembl
RefSeq Acc Id: NM_001081271   ⟹   NP_001074740
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391947,129,474 - 47,132,613 (-)NCBI
GRCm381947,141,035 - 47,144,174 (-)ENTREZGENE
MGSCv371947,215,525 - 47,218,664 (-)RGD
Celera1947,910,334 - 47,913,457 (-)RGD
cM Map19 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001074740 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAX76677 (Get FASTA)   NCBI Sequence Viewer  
  D3Z291 (Get FASTA)   NCBI Sequence Viewer  
  EDL42030 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000107444
  ENSMUSP00000107444.2
RefSeq Acc Id: NP_001074740   ⟸   NM_001081271
- UniProtKB: D3Z291 (UniProtKB/Swiss-Prot),   A0A1Y1C8H8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000107444   ⟸   ENSMUST00000111813

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z291-F1-model_v2 AlphaFold D3Z291 1-348 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3643383 AgrOrtholog
Ensembl Genes ENSMUSG00000079258 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000111813 ENTREZGENE
  ENSMUST00000111813.3 UniProtKB/Swiss-Prot
InterPro CALHM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:546729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:3643383 ENTREZGENE
NCBI Gene 546729 ENTREZGENE
PANTHER PTHR32261 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR32261:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ca_hom_mod UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Calhm1 PhenoGen
UniProt A0A1Y1C8H8 ENTREZGENE, UniProtKB/TrEMBL
  CAHM1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE