Imported Disease Annotations - ClinVarObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Il20 | Mouse | autistic disorder | | ISO | IL20 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Autism | ClinVar | PMID:21681106 and PMID:30208311 | Il20 | Mouse | common variable immunodeficiency 7 | | ISO | IL20 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Immunodeficiency more ... | ClinVar | PMID:28492532 | Il20 | Mouse | gastrointestinal stromal tumor | | ISO | IL20 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Gastrointestinal stromal tumor | ClinVar | PMID:28492532 | Il20 | Mouse | Hypokalemic Periodic Paralysis, Type 1 | | ISO | IL20 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Hypokalemic periodic paralysis and type 1 | ClinVar | PMID:28492532 | Il20 | Mouse | inflammatory bowel disease | | ISO | IL20 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inflammatory bowel disease | ClinVar | PMID:28492532 | Il20 | Mouse | parathyroid carcinoma | | ISO | IL20 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Parathyroid carcinoma | ClinVar | PMID:28492532 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Watched Genes
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Imported Disease Annotations - CTD
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations Click to see Annotation Detail View
Imported Annotations - KEGG (archival)
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Molecular Function
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | The association between the IL-20-1723C-->G allele on the 1q chromosome and psoriasis triggered or exacerbated by an upper respiratory tract infection in the Chinese Han population. | Chen XY, etal., Dermatology. 2011 Feb;222(1):24-30. Epub 2010 Nov 27. |
| 2. | Interleukin-20 antibody is a potential therapeutic agent for experimental arthritis. | Hsu YH and Chang MS, Arthritis Rheum. 2010 Nov;62(11):3311-21. doi: 10.1002/art.27689. |
| 3. | Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis. | Hsu YH, etal., Arthritis Rheum. 2006 Sep;54(9):2722-33. |
| 4. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 6. | Interleukin-20 targets renal cells and is associated with chronic kidney disease. | Wei CC, etal., Biochem Biophys Res Commun. 2008 Sep 26;374(3):448-53. Epub 2008 Jul 17. |
Additional References at PubMed
| PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11163236 | PMID:11217851 | PMID:11470428 | PMID:12466851 | PMID:12477932 | PMID:12855566 | PMID:16141072 | PMID:16141073 | PMID:16778121 |
| PMID:17878297 | PMID:18771958 | PMID:20562862 | PMID:21844205 | PMID:22238453 | PMID:24194600 | PMID:26162095 | PMID:26176762 | PMID:27075747 | PMID:28125663 | PMID:33610678 | PMID:34403503 |
| PMID:34557075 | PMID:35486004 | PMID:35613844 | PMID:37884352 | PMID:38355793 |
Genomics
Comparative Map Data
| Il20 (Mus musculus - house mouse) |
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| IL20 (Homo sapiens - human) |
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| Il20 (Rattus norvegicus - Norway rat) |
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| Il20 (Chinchilla lanigera - long-tailed chinchilla) |
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| IL20 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| IL20 (Canis lupus familiaris - dog) |
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| Il20 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| IL20 (Sus scrofa - pig) |
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| IL20 (Chlorocebus sabaeus - green monkey) |
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| Il20 (Heterocephalus glaber - naked mole-rat) |
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miRNA Target Status
Predicted Target Of
| The detailed report is available here: |  | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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QTLs in Region (GRCm39)
| The following QTLs overlap with this region. | | Full Report | | CSV | | TAB | | Printer | | Gviewer |
Markers in Region
| D1Mit345 |
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Expression
RNA-SEQ Expression
Sequence
Nucleotide Sequences
| Ensembl Acc Id: | ENSMUST00000027673 ⟹ ENSMUSP00000027673 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSMUST00000188581 ⟹ ENSMUSP00000141088 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001311091 ⟹ NP_001298020 | ||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | NM_021380 ⟹ NP_067355 | ||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
Protein Sequences
| RefSeq Acc Id: | NP_067355 ⟸ NM_021380 |
| - Peptide Label: | isoform 1 precursor |
| - UniProtKB: | Q9JKV9 (UniProtKB/Swiss-Prot), Q2NKI0 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | NP_001298020 ⟸ NM_001311091 |
| - Peptide Label: | isoform 2 |
| - UniProtKB: | Q2THG5 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSMUSP00000027673 ⟸ ENSMUST00000027673 |
| Ensembl Acc Id: | ENSMUSP00000141088 ⟸ ENSMUST00000188581 |