Ttc24 (tetratricopeptide repeat domain 24) - Rat Genome Database

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Gene: Ttc24 (tetratricopeptide repeat domain 24) Mus musculus
Analyze
Symbol: Ttc24
Name: tetratricopeptide repeat domain 24
RGD ID: 1616584
MGI Page MGI
Description: Orthologous to human TTC24 (tetratricopeptide repeat domain 24).
Type: protein-coding (Ensembl: transcribed_unitary_pseudogene)
RefSeq Status: PROVISIONAL
Previously known as: A430025D11Rik; MGC58815; tetratricopeptide repeat protein 24; TPR repeat protein 24
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,976,717 - 87,985,611 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl387,976,717 - 87,985,611 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl387,977,334 - 87,982,824 (-)EnsemblGRCm39 Ensembl
GRCm38388,069,410 - 88,078,304 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,069,410 - 88,078,304 (-)EnsemblGRCm38mm10GRCm38
MGSCv37387,873,332 - 87,882,226 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,155,337 - 88,164,231 (-)NCBIMGSCv36mm8
Celera388,108,991 - 88,117,903 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073  


Genomics

Comparative Map Data
Ttc24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,976,717 - 87,985,611 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl387,976,717 - 87,985,611 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl387,977,334 - 87,982,824 (-)EnsemblGRCm39 Ensembl
GRCm38388,069,410 - 88,078,304 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,069,410 - 88,078,304 (-)EnsemblGRCm38mm10GRCm38
MGSCv37387,873,332 - 87,882,226 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36388,155,337 - 88,164,231 (-)NCBIMGSCv36mm8
Celera388,108,991 - 88,117,903 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.78NCBI
TTC24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,579,723 - 156,587,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,579,723 - 156,587,719 (+)EnsemblGRCh38hg38GRCh38
GRCh371156,549,515 - 156,557,511 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361154,818,481 - 154,823,526 (+)NCBINCBI36Build 36hg18NCBI36
Celera1129,620,311 - 129,627,354 (+)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1127,907,248 - 127,914,290 (+)NCBIHuRef
CHM1_11157,945,711 - 157,952,754 (+)NCBICHM1_1
T2T-CHM13v2.01155,716,091 - 155,724,195 (+)NCBIT2T-CHM13v2.0
Ttc24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82175,818,921 - 175,830,991 (-)NCBIGRCr8
mRatBN7.22173,525,204 - 173,533,182 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,524,600 - 173,533,107 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02187,426,432 - 187,438,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2187,430,767 - 187,435,323 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02206,833,574 - 206,841,478 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,138,735 - 180,143,501 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2167,468,325 - 167,480,376 (-)NCBICelera
Cytogenetic Map2q34NCBI
Ttc24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555452,670,629 - 2,679,093 (+)NCBIChiLan1.0ChiLan1.0
TTC24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2193,256,094 - 93,263,081 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1192,990,621 - 92,997,566 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01131,925,121 - 131,931,589 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11135,748,836 - 135,754,007 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,747,196 - 135,754,227 (+)Ensemblpanpan1.1panPan2
TTC24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,372,960 - 41,381,514 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha740,860,605 - 40,869,172 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,236,459 - 41,245,096 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1741,018,101 - 41,026,655 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,071,346 - 41,079,901 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0741,355,024 - 41,363,582 (-)NCBIUU_Cfam_GSD_1.0
Ttc24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505826,728,410 - 26,735,988 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365805,758,792 - 5,766,327 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,500,564 - 93,510,815 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,500,900 - 93,512,039 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24102,275,794 - 102,284,140 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTC24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1207,275,898 - 7,289,531 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl207,275,064 - 7,281,253 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660386,572,293 - 6,579,465 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttc24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248851,768,702 - 1,777,349 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ttc24
271 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:311
Count of miRNA genes:202
Interacting mature miRNAs:222
Transcripts:ENSMUST00000050258, ENSMUST00000064550
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
10043981Cia5a_mcollagen induced arthritis QTL 5a (mouse)Not determined38717045489140094Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000050258   ⟹   ENSMUSP00000061571
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl387,976,717 - 87,985,611 (-)Ensembl
GRCm38.p6 Ensembl388,069,410 - 88,078,304 (-)Ensembl
Ensembl Acc Id: ENSMUST00000064550
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl387,977,120 - 87,979,367 (-)Ensembl
GRCm38.p6 Ensembl388,069,813 - 88,072,060 (-)Ensembl
Ensembl Acc Id: ENSMUST00000238487
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl387,976,717 - 87,985,611 (-)Ensembl
GRCm38.p6 Ensembl388,069,410 - 88,078,304 (-)Ensembl
Ensembl Acc Id: ENSMUST00000238508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl387,977,334 - 87,982,824 (-)Ensembl
GRCm38.p6 Ensembl388,070,027 - 88,075,517 (-)Ensembl
RefSeq Acc Id: NM_172526   ⟹   NP_766114
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39387,976,717 - 87,985,611 (-)NCBI
GRCm38388,069,410 - 88,078,304 (-)NCBI
MGSCv37387,873,332 - 87,882,226 (-)RGD
Celera388,108,991 - 88,117,903 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_766114   ⟸   NM_172526
- UniProtKB: Q7TPM2 (UniProtKB/Swiss-Prot),   Q8BYG0 (UniProtKB/Swiss-Prot),   B9EJT8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000061571   ⟸   ENSMUST00000050258

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BYG0-F1-model_v2 AlphaFold Q8BYG0 1-334 view protein structure

Promoters
RGD ID:6881092
Promoter ID:EPDNEW_M3997
Type:initiation region
Name:Ttc24_1
Description:Mus musculus tetratricopeptide repeat domain 24 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38388,072,052 - 88,072,112EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2443841 AgrOrtholog
Ensembl Genes ENSMUSG00000051036 Ensembl
  ENSMUSG00000121872 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000238487 ENTREZGENE
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:214191 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2443841 ENTREZGENE
NCBI Gene 214191 ENTREZGENE
PANTHER PTHR47050 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TETRATRICOPEPTIDE REPEAT PROTEIN 24 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TPR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ttc24 PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B9EJT8 ENTREZGENE, UniProtKB/TrEMBL
  Q7TPM2 ENTREZGENE
  Q8BYG0 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q7TPM2 UniProtKB/Swiss-Prot