Alms1 (ALMS1, centrosome and basal body associated) - Rat Genome Database

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Gene: Alms1 (ALMS1, centrosome and basal body associated) Mus musculus
Analyze
Symbol: Alms1
Name: ALMS1, centrosome and basal body associated
RGD ID: 1616534
MGI Page MGI
Description: Enables alpha-actinin binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cholesterol homeostasis; neuron development; and ovulation. Predicted to be located in ciliary basal body. Predicted to be active in centriole; centrosome; and cytosol. Is expressed in several structures, including aorta; central nervous system; genitourinary system; gut; and sensory organ. Used to study Alstrom syndrome and obesity. Human ortholog(s) of this gene implicated in Alstrom syndrome. Orthologous to human ALMS1 (ALMS1 centrosome and basal body associated protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Alstrom syndrome 1; Alstrom syndrome 1 homolog; Alstrom syndrome protein 1 homolog; bbb; centrosome-associated protein ALMS1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Alms1-ps1   Alms1-ps2  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,564,482 - 85,698,973 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl685,564,513 - 85,679,735 (+)EnsemblGRCm39 Ensembl
GRCm38685,587,498 - 85,726,611 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,587,531 - 85,702,753 (+)EnsemblGRCm38mm10GRCm38
MGSCv37685,537,525 - 85,652,745 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36685,553,189 - 85,668,300 (+)NCBIMGSCv36mm8
Celera687,559,405 - 87,708,447 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centriole  (IBA,ISO)
centrosome  (IBA,ISO)
ciliary basal body  (ISO)
cytosol  (IBA)
spindle pole  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal circulating cholesterol level  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal eye physiology  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal locomotor behavior  (IEA)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal renal tubule epithelial cell primary cilium morphology  (IAGP)
abnormal retina outer nuclear layer morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
albuminuria  (IAGP)
crystalluria  (IAGP)
degranulated pancreatic beta cells  (IAGP)
dilated proximal convoluted tubule  (IAGP)
dilated renal tubule  (IAGP)
enlarged kidney  (IAGP)
enlarged liver  (IAGP)
hepatic steatosis  (IAGP)
hyperglycemia  (IAGP)
impaired glucose tolerance  (IEA)
impaired hearing  (IEA)
increased body size  (IEA)
increased body weight  (IAGP)
increased circulating amylase level  (IEA)
increased circulating cholesterol level  (IAGP)
increased circulating HDL cholesterol level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating leptin level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased fasting circulating glucose level  (IEA)
increased fat cell size  (IAGP)
increased food intake  (IAGP)
increased kidney apoptosis  (IAGP)
increased kidney cell proliferation  (IAGP)
increased kidney weight  (IAGP)
increased liver weight  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased susceptibility to age-related retinal degeneration  (IAGP)
increased susceptibility to weight gain  (IAGP)
increased total body fat amount  (IAGP)
increased urine protein level  (IAGP)
increased white adipose tissue amount  (IAGP)
insulin resistance  (IAGP)
liver fibrosis  (IAGP)
macrovesicular hepatic steatosis  (IAGP)
microvesicular hepatic steatosis  (IAGP)
obese  (IAGP)
pancreatic islet hyperplasia  (IAGP)
retina outer nuclear layer degeneration  (IAGP)
retina photoreceptor degeneration  (IAGP)
retina pigment epithelium atrophy  (IAGP)
seminiferous tubule degeneration  (IAGP)
small gonad  (IAGP)
tubulointerstitial nephritis  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Fat aussie--a new Alstrom syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis. Arsov T, etal., Mol Endocrinol. 2006 Jul;20(7):1610-22. Epub 2006 Mar 2.
2. Alms1-disrupted mice recapitulate human Alstrom syndrome. Collin GB, etal., Hum Mol Genet. 2005 Aug 15;14(16):2323-33. Epub 2005 Jul 6.
3. Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome. Collin GB, etal., Nat Genet. 2002 May;31(1):74-8. Epub 2002 Apr 8.
4. Novel ALMS1 mutations in Chinese patients with Alstrom syndrome. Liang X, etal., Mol Vis. 2013 Sep 7;19:1885-91. eCollection 2013.
5. Syndromic obesity and diabetes: changes in body composition with age and mutation analysis of ALMS1 in 12 United Kingdom kindreds with Alstrom syndrome. Minton JA, etal., J Clin Endocrinol Metab. 2006 Aug;91(8):3110-6. Epub 2006 May 23.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Common variations in the ALMS1 gene do not contribute to susceptibility to type 2 diabetes in a large white UK population. Patel S, etal., Diabetologia. 2006 Jun;49(6):1209-13. Epub 2006 Apr 7.
8. Molecular approach in the study of Alstrom syndrome: analysis of ten Spanish families. Pineiro-Gallego T, etal., Mol Vis. 2012;18:1794-802. Epub 2012 Jul 3.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15368895   PMID:16141072   PMID:16141073  
PMID:16516152   PMID:16602821   PMID:17015433   PMID:17206865   PMID:20381594   PMID:21071598   PMID:21267068   PMID:21873635   PMID:22581473   PMID:22693585   PMID:24194600   PMID:24595103  
PMID:25299671   PMID:25670793   PMID:26035863   PMID:27757953   PMID:27803297   PMID:28346477   PMID:28842428   PMID:28859131   PMID:29133593   PMID:29688375   PMID:30945293   PMID:31302159  
PMID:32290105   PMID:32325033   PMID:32994277   PMID:34062281   PMID:34106786   PMID:34147365   PMID:37252956   PMID:37712194   PMID:38355793   PMID:38583571   PMID:38756069   PMID:39172787  


Genomics

Comparative Map Data
Alms1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,564,482 - 85,698,973 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl685,564,513 - 85,679,735 (+)EnsemblGRCm39 Ensembl
GRCm38685,587,498 - 85,726,611 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,587,531 - 85,702,753 (+)EnsemblGRCm38mm10GRCm38
MGSCv37685,537,525 - 85,652,745 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36685,553,189 - 85,668,300 (+)NCBIMGSCv36mm8
Celera687,559,405 - 87,708,447 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.48NCBI
ALMS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38273,385,758 - 73,609,919 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl273,385,758 - 73,625,166 (+)EnsemblGRCh38hg38GRCh38
GRCh37273,612,886 - 73,837,046 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36273,466,394 - 73,690,554 (+)NCBINCBI36Build 36hg18NCBI36
Build 34273,524,540 - 73,748,701NCBI
Celera273,463,729 - 73,687,908 (+)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef273,348,377 - 73,572,081 (+)NCBIHuRef
CHM1_1273,543,709 - 73,767,862 (+)NCBICHM1_1
T2T-CHM13v2.0273,398,811 - 73,623,015 (+)NCBIT2T-CHM13v2.0
Alms1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84119,683,085 - 119,783,471 (+)NCBIGRCr8
mRatBN7.24118,125,581 - 118,226,005 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4118,125,607 - 118,226,005 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4123,606,944 - 123,707,620 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04119,382,049 - 119,482,408 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04117,995,664 - 118,095,939 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04117,371,544 - 117,472,310 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,371,659 - 117,472,198 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04181,947,469 - 182,048,235 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,846,037 - 119,946,085 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14120,087,754 - 120,190,647 (+)NCBI
Celera4107,106,971 - 107,206,695 (+)NCBICelera
Cytogenetic Map4q34NCBI
Alms1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542412,130,607 - 12,258,522 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542412,130,496 - 12,258,684 (-)NCBIChiLan1.0ChiLan1.0
ALMS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21252,762,287 - 52,994,559 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A52,765,040 - 52,997,312 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A73,438,657 - 73,671,313 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A74,926,650 - 75,158,734 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A74,926,650 - 75,152,139 (+)Ensemblpanpan1.1panPan2
ALMS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,301,397 - 49,513,729 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1749,301,606 - 49,513,625 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,945,100 - 49,160,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01750,163,595 - 50,379,703 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11749,179,726 - 49,395,827 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01749,247,116 - 49,462,601 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,806,151 - 50,021,717 (-)NCBIUU_Cfam_GSD_1.0
Alms1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,228,877 - 11,418,533 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493649117,152,759 - 17,342,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALMS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,253,750 - 69,417,189 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,253,742 - 69,417,043 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,455,187 - 72,619,961 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALMS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,571,894 - 33,795,404 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1433,573,296 - 33,789,549 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604578,295,878 - 78,526,188 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alms1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624762128,491 - 269,006 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624762129,349 - 268,945 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Alms1
2603 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:41
Interacting mature miRNAs:41
Transcripts:ENSMUST00000072018
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671958006105958152Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67707698389976982Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671958006105958152Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67797698396976961Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
12792979Fbmd2_mfemoral bone mineral density 2, females only (mouse)675026989115026943Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67552133992584431Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67552133994202936Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65842456692424693Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671552042105552160Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67129960593441074Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7129960586252701Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675424566104480516Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65851741692517416Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684099474118099474Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675584287109584431Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670402880104403016Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670402880104403016Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676440930110441074Mouse
15039373Adip28_madiposity 28 (mouse)65628519490285194Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65628519490285194Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675693484109693678Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666690851100691013Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670402880104403016Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681476981102176961Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67552133994202936Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66003466394034782Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678606487121092347Mouse

Markers in Region
Alms1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
cM Map6 UniSTS
Alms1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6C3UniSTS
cM Map6 UniSTS
Alms1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6C3UniSTS


Sequence


Ensembl Acc Id: ENSMUST00000072018   ⟹   ENSMUSP00000071904
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,564,513 - 85,679,735 (+)Ensembl
GRCm38.p6 Ensembl685,587,531 - 85,702,753 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201221
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,643,665 - 85,646,705 (+)Ensembl
GRCm38.p6 Ensembl685,666,683 - 85,669,723 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201244
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,616,445 - 85,619,173 (+)Ensembl
GRCm38.p6 Ensembl685,639,463 - 85,642,191 (+)Ensembl
Ensembl Acc Id: ENSMUST00000202809
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,623,712 - 85,628,529 (+)Ensembl
GRCm38.p6 Ensembl685,646,730 - 85,651,547 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213058   ⟹   ENSMUSP00000148796
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl685,564,628 - 85,679,620 (+)Ensembl
GRCm38.p6 Ensembl685,587,646 - 85,702,638 (+)Ensembl
RefSeq Acc Id: NM_145223   ⟹   NP_660258
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,564,513 - 85,679,733 (+)NCBI
GRCm38685,587,531 - 85,702,751 (+)NCBI
MGSCv37685,537,525 - 85,652,745 (+)RGD
Celera687,559,405 - 87,708,447 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006506050   ⟹   XP_006506113
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,564,496 - 85,679,737 (+)NCBI
GRCm38685,587,512 - 85,702,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006506053   ⟹   XP_006506116
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,564,496 - 85,698,973 (+)NCBI
GRCm38685,587,512 - 85,721,995 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001785126
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,564,482 - 85,654,889 (+)NCBI
GRCm38685,587,498 - 85,677,907 (+)NCBI
Sequence:
RefSeq Acc Id: XR_377445
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39685,564,482 - 85,628,359 (+)NCBI
GRCm38685,587,498 - 85,651,377 (+)NCBI
Sequence:
RefSeq Acc Id: NP_660258   ⟸   NM_145223
- UniProtKB: Q6A084 (UniProtKB/Swiss-Prot),   E9QKT8 (UniProtKB/Swiss-Prot),   Q8C9N9 (UniProtKB/Swiss-Prot),   Q8K4E0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006506116   ⟸   XM_006506053
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006506113   ⟸   XM_006506050
- Peptide Label: isoform X1
- UniProtKB: A0A1D5RMI8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000071904   ⟸   ENSMUST00000072018
Ensembl Acc Id: ENSMUSP00000148796   ⟸   ENSMUST00000213058
Protein Domains
ALMS motif

Promoters
RGD ID:6838926
Promoter ID:MM_KWN:46688
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000059068
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36685,537,459 - 85,537,959 (+)MPROMDB
RGD ID:6890238
Promoter ID:EPDNEW_M8570
Type:multiple initiation site
Name:Alms1_1
Description:Mus musculus ALMS1, centrosome and basal body associated , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38685,587,613 - 85,587,673EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1934606 AgrOrtholog
Ensembl Genes ENSMUSG00000063810 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000072018 ENTREZGENE
  ENSMUST00000072018.6 UniProtKB/Swiss-Prot
  ENSMUST00000213058 ENTREZGENE
  ENSMUST00000213058.2 UniProtKB/TrEMBL
InterPro ALMS_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALMS_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:236266 UniProtKB/Swiss-Prot
MGD MGI:1934606 ENTREZGENE
NCBI Gene 236266 ENTREZGENE
PANTHER ALMS1-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21553:SF22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ALMS_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALMS_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Alms1 PhenoGen
UniProt A0A1D5RMI8 ENTREZGENE, UniProtKB/TrEMBL
  ALMS1_MOUSE UniProtKB/Swiss-Prot
  E9QKT8 ENTREZGENE
  Q6A084 ENTREZGENE
  Q8C9N9 ENTREZGENE
  Q8K4E0 ENTREZGENE
UniProt Secondary E9QKT8 UniProtKB/Swiss-Prot
  Q6A084 UniProtKB/Swiss-Prot
  Q8C9N9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-21 Alms1  ALMS1, centrosome and basal body associated    Alstrom syndrome 1  Symbol and/or name change 5135510 APPROVED
2012-07-10 Alms1  Alstrom syndrome 1  Alms1  Alstrom syndrome 1 homolog (human)  Symbol and/or name change 5135510 APPROVED