Cdc20b (cell division cycle 20B) - Rat Genome Database

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Gene: Cdc20b (cell division cycle 20B) Mus musculus
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Symbol: Cdc20b
Name: cell division cycle 20B
RGD ID: 1616527
MGI Page MGI
Description: Predicted to enable anaphase-promoting complex binding activity and ubiquitin ligase activator activity. Involved in de novo centriole assembly. Located in deuterosome. Orthologous to human CDC20B (cell division cycle 20B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cell division cycle 20 homolog B; cell division cycle 20 homolog B (S. cerevisiae); cell division cycle protein 20 homolog B; EG238896; EG622422; predicted gene, EG622422
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913113,171,514 - 113,257,553 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13113,171,645 - 113,227,729 (+)EnsemblGRCm39 Ensembl
GRCm3813113,034,975 - 113,121,019 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13113,035,111 - 113,091,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713113,844,876 - 113,881,343 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613114,175,546 - 114,212,013 (+)NCBIMGSCv36mm8
Celera13117,372,711 - 117,401,874 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1363.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21873635   PMID:30405130   PMID:38355793  


Genomics

Comparative Map Data
Cdc20b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913113,171,514 - 113,257,553 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13113,171,645 - 113,227,729 (+)EnsemblGRCm39 Ensembl
GRCm3813113,034,975 - 113,121,019 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13113,035,111 - 113,091,195 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713113,844,876 - 113,881,343 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613114,175,546 - 114,212,013 (+)NCBIMGSCv36mm8
Celera13117,372,711 - 117,401,874 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1363.93NCBI
CDC20B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38555,112,971 - 55,173,177 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl555,112,971 - 55,173,177 (-)EnsemblGRCh38hg38GRCh38
GRCh37554,408,799 - 54,469,005 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36554,444,580 - 54,504,760 (-)NCBINCBI36Build 36hg18NCBI36
Celera551,361,686 - 51,421,844 (-)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef551,381,983 - 51,442,171 (-)NCBIHuRef
CHM1_1554,412,293 - 54,472,491 (-)NCBICHM1_1
T2T-CHM13v2.0555,940,297 - 56,000,463 (-)NCBIT2T-CHM13v2.0
Cdc20b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2244,688,349 - 44,738,056 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.0244,916,806 - 44,947,860 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0263,953,314 - 64,002,072 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4244,435,662 - 44,484,469 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera240,462,676 - 40,511,461 (+)NCBICelera
Cytogenetic Map2q14NCBI
Cdc20b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544612,494,735 - 12,553,130 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544612,494,176 - 12,551,397 (+)NCBIChiLan1.0ChiLan1.0
CDC20B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2458,767,265 - 58,829,371 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1556,920,913 - 56,982,996 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0558,856,370 - 58,918,463 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1560,478,977 - 60,538,264 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl560,478,977 - 60,538,264 (+)Ensemblpanpan1.1panPan2
CDC20B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,501,365 - 42,547,336 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,502,471 - 42,544,841 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,546,989 - 39,592,913 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0242,960,120 - 43,009,376 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl242,961,226 - 43,028,045 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1240,030,611 - 40,072,137 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0240,840,823 - 40,889,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0241,663,376 - 41,712,698 (-)NCBIUU_Cfam_GSD_1.0
Cdc20b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213203,656,675 - 203,704,624 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648012,593,216 - 12,640,661 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648012,593,216 - 12,640,661 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC20B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1634,294,272 - 34,349,242 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11634,294,486 - 34,354,588 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CDC20B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1451,349,486 - 51,408,437 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl451,351,574 - 51,406,488 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666049219,601 - 275,784 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc20b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247594,109,203 - 4,176,824 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247594,112,012 - 4,174,838 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdc20b
3607 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:841
Count of miRNA genes:281
Interacting mature miRNAs:303
Transcripts:ENSMUST00000109244, ENSMUST00000180543, ENSMUST00000181117, ENSMUST00000181568, ENSMUST00000181741
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142334Svtms_msurvival time modifier of Sod2 (mouse)Not determined13107613580119476372Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382739968116740106Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1479239045113239162Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393875267120883175Mouse
1357468Rplag_mreduced platelet aggregation (mouse)Not determined1395502130120883175Mouse
12879496Fexq2_mfear expression QTL 2 (mouse)13100741519120883175Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379239045113239162Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386148119120461536Mouse
4141704Hipq1_mhyperinsulin production QTL 1 (mouse)Not determined110409487119476372Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391383692120883175Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386341617120341758Mouse
1558763Gct9_mgranulosa cell tumorigenesis 9 (mouse)Not determined1395036824120883175Mouse
4142338Skmw18_mskeletal muscle weight 18 (mouse)Not determined1394528399120883175Mouse
4141826Tbqt5_mtibia bone quality traits 5 (mouse)Not determined13103341617117043216Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383876060117876256Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391965303120883175Mouse
14746974Manh75_mmandible shape 75 (mouse)1399386647120883175Mouse
4142400Tgq24_mtriglyceride QTL 24 (mouse)Not determined102602630120883175Mouse

Markers in Region
AW494114  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3813113,093,856 - 113,093,994UniSTSGRCm38
MGSCv3713113,884,064 - 113,884,202UniSTSGRCm37
Celera13117,414,523 - 117,414,661UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map13D2.2UniSTS
cM Map1364.0UniSTS
Whitehead/MRC_RH13973.44UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000109244   ⟹   ENSMUSP00000104867
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13113,171,913 - 113,227,729 (+)Ensembl
GRCm38.p6 Ensembl13113,035,379 - 113,091,195 (+)Ensembl
Ensembl Acc Id: ENSMUST00000180543   ⟹   ENSMUSP00000137651
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13113,171,645 - 113,174,858 (+)Ensembl
GRCm38.p6 Ensembl13113,035,111 - 113,038,324 (+)Ensembl
Ensembl Acc Id: ENSMUST00000181117   ⟹   ENSMUSP00000137915
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13113,171,913 - 113,227,729 (+)Ensembl
GRCm38.p6 Ensembl13113,035,379 - 113,091,195 (+)Ensembl
Ensembl Acc Id: ENSMUST00000181568   ⟹   ENSMUSP00000137849
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13113,171,913 - 113,227,729 (+)Ensembl
GRCm38.p6 Ensembl13113,035,379 - 113,091,195 (+)Ensembl
Ensembl Acc Id: ENSMUST00000181741   ⟹   ENSMUSP00000137759
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl13113,171,921 - 113,174,858 (+)Ensembl
GRCm38.p6 Ensembl13113,035,387 - 113,038,324 (+)Ensembl
RefSeq Acc Id: NM_001281487   ⟹   NP_001268416
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,913 - 113,227,669 (+)NCBI
GRCm3813113,035,379 - 113,091,135 (+)NCBI
Celera13117,353,405 - 117,401,870 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517653   ⟹   XP_006517716
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,531 - 113,229,616 (+)NCBI
GRCm3813113,034,993 - 113,093,082 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006517655   ⟹   XP_006517718
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,529 - 113,257,553 (+)NCBI
GRCm3813113,034,990 - 113,121,019 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011244659   ⟹   XP_011242961
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,527 - 113,222,294 (+)NCBI
GRCm3813113,034,988 - 113,085,760 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011244660   ⟹   XP_011242962
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,528 - 113,223,097 (+)NCBI
GRCm3813113,034,989 - 113,086,563 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011244661   ⟹   XP_011242963
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,528 - 113,222,294 (+)NCBI
GRCm3813113,034,989 - 113,085,760 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011244662   ⟹   XP_011242964
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,527 - 113,222,294 (+)NCBI
GRCm3813113,034,988 - 113,085,760 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030247263   ⟹   XP_030103123
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,525 - 113,222,294 (+)NCBI
GRCm3813113,034,986 - 113,085,760 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036158047   ⟹   XP_036013940
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,529 - 113,257,553 (+)NCBI
Sequence:
RefSeq Acc Id: XR_873755
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3913113,171,514 - 113,216,485 (+)NCBI
GRCm3813113,034,975 - 113,079,945 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001268416   ⟸   NM_001281487
- UniProtKB: D3Z3I0 (UniProtKB/TrEMBL),   M0QWN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517718   ⟸   XM_006517655
- Peptide Label: isoform X7
- UniProtKB: M0QWN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517716   ⟸   XM_006517653
- Peptide Label: isoform X3
- UniProtKB: M0QWN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011242962   ⟸   XM_011244660
- Peptide Label: isoform X2
- UniProtKB: M0QWN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011242961   ⟸   XM_011244659
- Peptide Label: isoform X1
- UniProtKB: M0QWN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011242963   ⟸   XM_011244661
- Peptide Label: isoform X4
- UniProtKB: M0QWN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011242964   ⟸   XM_011244662
- Peptide Label: isoform X5
- UniProtKB: M0QWN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030103123   ⟸   XM_030247263
- Peptide Label: isoform X8
- UniProtKB: M0QWN1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000104867   ⟸   ENSMUST00000109244
Ensembl Acc Id: ENSMUSP00000137759   ⟸   ENSMUST00000181741
Ensembl Acc Id: ENSMUSP00000137849   ⟸   ENSMUST00000181568
Ensembl Acc Id: ENSMUSP00000137915   ⟸   ENSMUST00000181117
Ensembl Acc Id: ENSMUSP00000137651   ⟸   ENSMUST00000180543
RefSeq Acc Id: XP_036013940   ⟸   XM_036158047
- Peptide Label: isoform X6
- UniProtKB: M0QWN1 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z3I0-F1-model_v2 AlphaFold D3Z3I0 1-519 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3644472 AgrOrtholog
Ensembl Genes ENSMUSG00000078926 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000109244 ENTREZGENE
  ENSMUST00000109244.9 UniProtKB/Swiss-Prot
  ENSMUST00000180543.8 UniProtKB/TrEMBL
  ENSMUST00000181117.8 UniProtKB/TrEMBL
  ENSMUST00000181568.8 UniProtKB/TrEMBL
  ENSMUST00000181741.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
InterPro Apc4-like_WD40_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cdc20/Fizzy UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:238896 UniProtKB/Swiss-Prot
MGD MGI:3644472 ENTREZGENE
NCBI Gene 238896 ENTREZGENE
PANTHER CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED UniProtKB/Swiss-Prot
  CELL DIVISION CYCLE PROTEIN 20 HOMOLOG B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19918 UniProtKB/TrEMBL
Pfam ANAPC4_WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cdc20b PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP WD40 repeat-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CD20B_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  M0QW47_MOUSE UniProtKB/TrEMBL
  M0QWC6_MOUSE UniProtKB/TrEMBL
  M0QWI6_MOUSE UniProtKB/TrEMBL
  M0QWN1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-04 Cdc20b  cell division cycle 20B  EG622422  predicted gene, EG622422  Data merged from RGD:1615423 737654 PROVISIONAL
2012-07-10 Cdc20b  cell division cycle 20B  Cdc20b  cell division cycle 20 homolog B (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED