Chd2 (chromodomain helicase DNA binding protein 2) - Rat Genome Database

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Gene: Chd2 (chromodomain helicase DNA binding protein 2) Mus musculus
Analyze
Symbol: Chd2
Name: chromodomain helicase DNA binding protein 2
RGD ID: 1616514
MGI Page MGI
Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and histone binding activity. Involved in gene expression and muscle organ development. Acts upstream of or within DNA damage response and hematopoietic stem cell differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study CHARGE syndrome. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 94. Orthologous to human CHD2 (chromodomain helicase DNA binding protein 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2810013C04Rik; 2810040A01Rik; 5630401D06Rik; AI851092; ATP-dependent helicase CHD2; BC029703; CHD-2; chromodomain-helicase-DNA-binding protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39773,076,400 - 73,191,494 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl773,076,386 - 73,191,578 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38773,426,652 - 73,541,746 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl773,426,638 - 73,541,830 (-)Ensemblmm10GRCm38
MGSCv37780,571,538 - 80,686,632 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36773,303,121 - 73,415,343 (-)NCBIMGSCv36mm8
Celera770,874,423 - 70,989,778 (-)NCBICelera
Cytogenetic Map7D1NCBI
cM Map741.85NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-citrinin  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
6-propyl-2-thiouracil  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (EXP)
carbon nanotube  (EXP)
carmustine  (ISO)
chrysene  (EXP)
clobetasol  (EXP)
clotrimazole  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
Dibutyl phosphate  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
erythromycin estolate  (ISO)
fenthion  (EXP)
fluoranthene  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (ISO)
glucose  (ISO)
hydralazine  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (EXP)
nicotine  (ISO)
nitrates  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
quercitrin  (ISO)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
tetraphene  (EXP)
thiram  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
troglitazone  (EXP)
tungsten  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (IBA)
nucleus  (IBA,IDA,IEA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood cell morphology/development  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal bone structure  (IEA)
abnormal cell cycle  (IAGP)
abnormal DNA repair  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal eye morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal liver morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal respiratory system physiology  (IAGP)
abnormal sinus arrhythmia  (IEA)
absent subcutaneous adipose tissue  (IAGP)
anophthalmia  (IAGP)
arteritis  (IAGP)
bile duct hyperplasia  (IAGP)
cardiac fibrosis  (IAGP)
cardiomyopathy  (IAGP)
cortical renal glomerulopathies  (IAGP)
dark spleen  (IAGP)
decreased birth body size  (IAGP)
decreased body length  (IEA)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IEA)
decreased erythrocyte cell number  (IEA)
decreased erythroid progenitor cell number  (IAGP)
decreased fetal size  (IAGP)
decreased hemoglobin content  (IEA)
decreased lymphocyte cell number  (IAGP)
decreased mean platelet volume  (IEA)
decreased prepulse inhibition  (IEA)
decreased subcutaneous adipose tissue amount  (IAGP)
decreased survivor rate  (IAGP)
decreased white adipose tissue amount  (IAGP)
disheveled coat  (IAGP)
endometrium hyperplasia  (IAGP)
enlarged heart  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
fetal growth retardation  (IAGP)
heart inflammation  (IAGP)
hemorrhage  (IAGP)
hepatic necrosis  (IAGP)
increased CD4-positive, alpha-beta T cell number  (IAGP)
increased cellular sensitivity to methylmethanesulfonate  (IAGP)
increased cellular sensitivity to ultraviolet irradiation  (IAGP)
increased cellular sensitivity to X-ray irradiation  (IAGP)
increased circulating alanine transaminase level  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased grip strength  (IEA)
increased heart atrium size  (IAGP)
increased lymphoma incidence  (IAGP)
increased megakaryocyte cell number  (IAGP)
increased spleen red pulp amount  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
interstitial pneumonia  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
lethargy  (IAGP)
lipidosis  (IAGP)
liver inflammation  (IAGP)
lordokyphosis  (IAGP)
lordosis  (IAGP)
lymphoid hyperplasia  (IAGP)
myocardial fiber degeneration  (IAGP)
myocarditis  (IAGP)
no abnormal phenotype detected  (IAGP)
pale kidney  (IAGP)
pallor  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
pulmonary alveolar edema  (IAGP)
pulmonary alveolar hemorrhage  (IAGP)
short tibia  (IEA)
tachypnea  (IAGP)
uterus cyst  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:14681479  
PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16810678   PMID:17967808   PMID:18386809   PMID:18799693   PMID:19137022   PMID:19142019   PMID:21267068   PMID:21873635  
PMID:22223433   PMID:22569126   PMID:23920106   PMID:25786798   PMID:26244796   PMID:26611327   PMID:27626380   PMID:27783602   PMID:28549158   PMID:29459677   PMID:30111840   PMID:30186101  
PMID:30277262   PMID:30344048   PMID:30550785   PMID:31541165   PMID:31704914   PMID:33230847   PMID:34043941   PMID:34321999   PMID:38355793  


Genomics

Comparative Map Data
Chd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39773,076,400 - 73,191,494 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl773,076,386 - 73,191,578 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38773,426,652 - 73,541,746 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl773,426,638 - 73,541,830 (-)Ensemblmm10GRCm38
MGSCv37780,571,538 - 80,686,632 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36773,303,121 - 73,415,343 (-)NCBIMGSCv36mm8
Celera770,874,423 - 70,989,778 (-)NCBICelera
Cytogenetic Map7D1NCBI
cM Map741.85NCBI
CHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381592,900,324 - 93,027,996 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1592,886,203 - 93,027,996 (+)Ensemblhg38GRCh38
GRCh371593,443,554 - 93,571,226 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361591,244,555 - 91,372,241 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341591,244,422 - 91,366,396NCBI
Celera1569,855,404 - 69,982,772 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1569,580,061 - 69,707,674 (+)NCBIHuRef
CHM1_11593,284,562 - 93,411,895 (+)NCBICHM1_1
T2T-CHM13v2.01590,662,587 - 90,790,268 (+)NCBIT2T-CHM13v2.0
Chd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81136,597,993 - 136,726,874 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1136,599,900 - 136,710,335 (-)EnsemblGRCr8
mRatBN7.21127,188,146 - 127,317,041 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1127,190,059 - 127,300,502 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1135,179,350 - 135,289,183 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01142,349,455 - 142,459,293 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,177,391 - 135,286,853 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01134,757,934 - 134,873,053 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,757,934 - 134,871,167 (-)Ensemblrn6Rnor6.0
Rnor_5.01135,782,462 - 135,897,354 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41128,609,727 - 128,720,325 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1119,322,047 - 119,431,932 (-)NCBICelera
RGSC_v3.11128,688,083 - 128,798,804 (-)NCBI
Cytogenetic Map1q31NCBI
Chd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541621,085,570 - 21,210,321 (+)Ensembl
ChiLan1.0NW_00495541621,085,570 - 21,210,321 (+)NCBIChiLan1.0ChiLan1.0
CHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21682,430,058 - 82,574,809 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11586,128,120 - 86,272,854 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01571,568,560 - 71,713,330 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11590,780,220 - 90,906,863 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1590,781,169 - 90,903,569 (+)EnsemblpanPan2panpan1.1
CHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1347,101,789 - 47,221,473 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl347,105,046 - 47,221,385 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha349,802,181 - 49,921,599 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0347,511,193 - 47,631,121 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl347,511,205 - 47,631,054 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1347,029,130 - 47,148,452 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0347,260,475 - 47,380,113 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0347,591,992 - 47,711,357 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Chd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640136,403,356 - 136,530,590 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364839,803,623 - 9,931,272 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364839,803,887 - 9,931,132 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl785,983,837 - 86,106,938 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1785,980,759 - 86,107,886 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2791,874,318 - 92,002,341 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12911,436,170 - 11,579,468 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2911,450,799 - 11,579,594 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605935,081,933 - 35,228,711 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476810,785,815 - 10,922,790 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476810,786,139 - 10,922,558 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Chd2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12126,955,367 - 127,067,636 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Chd2
5307 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:3041
Count of miRNA genes:913
Interacting mature miRNAs:1275
Transcripts:ENSMUST00000026895, ENSMUST00000038366, ENSMUST00000169922, ENSMUST00000172704, ENSMUST00000173785, ENSMUST00000181971
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76644974898349207Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74919327883193390Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7285710592582163Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74915922783235415Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74838446182384607Mouse
13506750Tbthq2_mtrabecular bone thickness QTL 2 (mouse)76565974877549748Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
12801463Rta1_mretinal aging 1 (mouse)76716802789089989Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
25314302Vmm2_mvariable multisystem mineralization 2, heart (mouse)74714974874149748Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse

Markers in Region
BB375928  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38773,523,857 - 73,523,996UniSTSGRCm38
MGSCv37780,668,743 - 80,668,882UniSTSGRCm37
Celera770,971,850 - 70,971,989UniSTS
Cytogenetic Map7D1UniSTS
Whitehead/MRC_RH7828.42UniSTS
AI851092  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38773,426,965 - 73,427,065UniSTSGRCm38
MGSCv37780,571,851 - 80,571,951UniSTSGRCm37
Celera770,874,736 - 70,874,836UniSTS
Cytogenetic Map7D1UniSTS
Whitehead/MRC_RH7828.72UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000026895   ⟹   ENSMUSP00000026895
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,150,728 - 73,191,493 (-)Ensembl
GRCm38.p6 Ensembl773,500,980 - 73,541,745 (-)Ensembl
Ensembl Acc Id: ENSMUST00000038366
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,101,561 - 73,111,481 (-)Ensembl
GRCm38.p6 Ensembl773,451,813 - 73,461,733 (-)Ensembl
Ensembl Acc Id: ENSMUST00000169922   ⟹   ENSMUSP00000126352
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,076,386 - 73,191,494 (-)Ensembl
GRCm38.p6 Ensembl773,426,638 - 73,541,746 (-)Ensembl
Ensembl Acc Id: ENSMUST00000172704   ⟹   ENSMUSP00000134484
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,157,608 - 73,187,369 (-)Ensembl
GRCm38.p6 Ensembl773,507,860 - 73,537,621 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173785   ⟹   ENSMUSP00000133714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,079,736 - 73,096,981 (-)Ensembl
GRCm38.p6 Ensembl773,429,988 - 73,447,233 (-)Ensembl
Ensembl Acc Id: ENSMUST00000181971   ⟹   ENSMUSP00000137985
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,098,992 - 73,105,340 (-)Ensembl
GRCm38.p6 Ensembl773,449,244 - 73,455,592 (-)Ensembl
Ensembl Acc Id: ENSMUST00000197642   ⟹   ENSMUSP00000142408
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,157,638 - 73,191,484 (-)Ensembl
GRCm38.p6 Ensembl773,507,890 - 73,541,736 (-)Ensembl
Ensembl Acc Id: ENSMUST00000197800
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,187,838 - 73,191,578 (-)Ensembl
GRCm38.p6 Ensembl773,538,090 - 73,541,830 (-)Ensembl
Ensembl Acc Id: ENSMUST00000198225
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,124,331 - 73,128,576 (-)Ensembl
GRCm38.p6 Ensembl773,474,583 - 73,478,828 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199601   ⟹   ENSMUSP00000143203
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,147,455 - 73,151,865 (-)Ensembl
GRCm38.p6 Ensembl773,497,707 - 73,502,117 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199641   ⟹   ENSMUSP00000142848
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,149,390 - 73,151,784 (-)Ensembl
GRCm38.p6 Ensembl773,499,642 - 73,502,036 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199809   ⟹   ENSMUSP00000142959
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,076,442 - 73,118,335 (-)Ensembl
GRCm38.p6 Ensembl773,426,694 - 73,468,587 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199831
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,124,324 - 73,130,750 (-)Ensembl
GRCm38.p6 Ensembl773,474,576 - 73,481,002 (-)Ensembl
Ensembl Acc Id: ENSMUST00000200218
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,189,546 - 73,191,273 (-)Ensembl
GRCm38.p6 Ensembl773,539,798 - 73,541,525 (-)Ensembl
Ensembl Acc Id: ENSMUST00000200423   ⟹   ENSMUSP00000142885
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,124,330 - 73,130,752 (-)Ensembl
GRCm38.p6 Ensembl773,474,582 - 73,481,004 (-)Ensembl
Ensembl Acc Id: ENSMUST00000200492
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,189,102 - 73,191,494 (-)Ensembl
GRCm38.p6 Ensembl773,539,354 - 73,541,746 (-)Ensembl
Ensembl Acc Id: ENSMUST00000206665
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,151,686 - 73,153,317 (-)Ensembl
GRCm38.p6 Ensembl773,501,938 - 73,503,569 (-)Ensembl
Ensembl Acc Id: ENSMUST00000208458   ⟹   ENSMUSP00000147180
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl773,079,390 - 73,093,999 (-)Ensembl
GRCm38.p6 Ensembl773,429,642 - 73,444,251 (-)Ensembl
RefSeq Acc Id: NM_001081345   ⟹   NP_001074814
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39773,076,400 - 73,191,494 (-)NCBI
GRCm38773,426,652 - 73,541,746 (-)ENTREZGENE
MGSCv37780,571,538 - 80,686,632 (-)RGD
Celera770,874,423 - 70,989,778 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001074814 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAE21274 (Get FASTA)   NCBI Sequence Viewer  
  BAE21396 (Get FASTA)   NCBI Sequence Viewer  
  BAE21742 (Get FASTA)   NCBI Sequence Viewer  
  E9PZM4 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000126352
  ENSMUSP00000126352.3
RefSeq Acc Id: NP_001074814   ⟸   NM_001081345
- UniProtKB: E9PZM4 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000026895   ⟸   ENSMUST00000026895
Ensembl Acc Id: ENSMUSP00000142408   ⟸   ENSMUST00000197642
Ensembl Acc Id: ENSMUSP00000134484   ⟸   ENSMUST00000172704
Ensembl Acc Id: ENSMUSP00000142959   ⟸   ENSMUST00000199809
Ensembl Acc Id: ENSMUSP00000143203   ⟸   ENSMUST00000199601
Ensembl Acc Id: ENSMUSP00000142848   ⟸   ENSMUST00000199641
Ensembl Acc Id: ENSMUSP00000147180   ⟸   ENSMUST00000208458
Ensembl Acc Id: ENSMUSP00000133714   ⟸   ENSMUST00000173785
Ensembl Acc Id: ENSMUSP00000137985   ⟸   ENSMUST00000181971
Ensembl Acc Id: ENSMUSP00000126352   ⟸   ENSMUST00000169922
Ensembl Acc Id: ENSMUSP00000142885   ⟸   ENSMUST00000200423
Protein Domains
ATP-dependent helicase CHD1-2/hrp3 HTH   Chromo   Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PZM4-F1-model_v2 AlphaFold E9PZM4 1-1827 view protein structure

Promoters
RGD ID:8664435
Promoter ID:EPDNEW_M10248
Type:initiation region
Name:Chd2_1
Description:Mus musculus chromodomain helicase DNA binding protein 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38773,541,746 - 73,541,806EPDNEW
RGD ID:6840826
Promoter ID:MM_KWN:51113
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   MEF_B6
Transcripts:ENSMUST00000038366
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36780,606,266 - 80,607,267 (-)MPROMDB
RGD ID:6840830
Promoter ID:MM_KWN:51115
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:UC009HRC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36780,682,021 - 80,683,262 (-)MPROMDB
RGD ID:6840829
Promoter ID:MM_KWN:51116
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001081345,   UC009HRD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36780,686,296 - 80,687,632 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2448567 AgrOrtholog
Ensembl Genes ENSMUSG00000078671 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000169922 ENTREZGENE
  ENSMUST00000169922.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.50.40 UniProtKB/Swiss-Prot
  3.40.50.10810 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  6.10.140.1440 UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
InterPro CDH1_2_SANT_HL1 UniProtKB/Swiss-Prot
  Chromo-like_dom_sf UniProtKB/Swiss-Prot
  Chromo/chromo_shadow_dom UniProtKB/Swiss-Prot
  Chromo_domain UniProtKB/Swiss-Prot
  Chromodomain_CS UniProtKB/Swiss-Prot
  DUF4208 UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  Hrp3-like_HTH UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  SNF2-like_sf UniProtKB/Swiss-Prot
  SNF2/RAD54-like_C UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
KEGG Report mmu:244059 UniProtKB/Swiss-Prot
MGD MGI:2448567 ENTREZGENE
NCBI Gene 244059 ENTREZGENE
PANTHER CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 2 UniProtKB/Swiss-Prot
  CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED UniProtKB/Swiss-Prot
Pfam CDH1_2_SANT_HL1 UniProtKB/Swiss-Prot
  Chromo UniProtKB/Swiss-Prot
  DUF4208 UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  Hrp3 UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
PhenoGen Chd2 PhenoGen
PROSITE CHROMO_1 UniProtKB/Swiss-Prot
  CHROMO_2 UniProtKB/Swiss-Prot
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
SMART CHROMO UniProtKB/Swiss-Prot
  DEXDc UniProtKB/Swiss-Prot
  DUF4208 UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
  SSF54160 UniProtKB/Swiss-Prot
UniProt A0A0G2JDK8_MOUSE UniProtKB/TrEMBL
  A0A0G2JEP1_MOUSE UniProtKB/TrEMBL
  A0A0G2JES5_MOUSE UniProtKB/TrEMBL
  A0A0G2JEZ3_MOUSE UniProtKB/TrEMBL
  A0A0G2JFK1_MOUSE UniProtKB/TrEMBL
  A0A140LJE4_MOUSE UniProtKB/TrEMBL
  CHD2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  F7CDZ7_MOUSE UniProtKB/TrEMBL
  G3UXJ4_MOUSE UniProtKB/TrEMBL
  G3UZG2_MOUSE UniProtKB/TrEMBL
  M0QWT0_MOUSE UniProtKB/TrEMBL
  Q3UZW3_MOUSE UniProtKB/TrEMBL
  Q3V0V7_MOUSE UniProtKB/TrEMBL
  Q3V177_MOUSE UniProtKB/TrEMBL