Chd7 (chromodomain helicase DNA binding protein 7) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Community Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Chd7 (chromodomain helicase DNA binding protein 7) Mus musculus
Analyze
Symbol: Chd7
Name: chromodomain helicase DNA binding protein 7
RGD ID: 1616427
MGI Page MGI
Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and promoter-specific chromatin binding activity. Acts upstream of or within several processes, including circulatory system development; embryonic morphogenesis; and nervous system development. Located in nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; lung; nervous system; and sensory organ. Used to study CHARGE syndrome. Human ortholog(s) of this gene implicated in CHARGE syndrome and hypogonadotropic hypogonadism 5 with or without anosmia. Orthologous to human CHD7 (chromodomain helicase DNA binding protein 7).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: A730019I05Rik; ATP-dependent helicase CHD7; CHD-7; chromodomain-helicase-DNA-binding protein 7; Cy; Cyc; Cycn; Cyn; Dz; Edy; F; Flo; GENA 47; Gena 52; GENA 60; L; Lda; metis; Mt; Ob; Obt; RP23-464N23.1; To; Todo; WBE1; Wh; Whi
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3948,690,345 - 8,868,449 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl48,690,406 - 8,867,659 (+)EnsemblGRCm39 Ensembl
GRCm3848,690,402 - 8,868,449 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl48,690,406 - 8,867,659 (+)EnsemblGRCm38mm10GRCm38
MGSCv3748,618,068 - 8,793,957 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3648,617,551 - 8,793,957 (+)NCBIMGSCv36mm8
Celera48,587,948 - 8,703,577 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult heart development  (IMP)
adult walking behavior  (IMP)
aorta development  (IMP)
aorta morphogenesis  (IMP)
artery morphogenesis  (IGI)
atrioventricular canal development  (IMP)
blood circulation  (IMP)
blood vessel development  (IMP)
blood vessel remodeling  (IMP)
camera-type eye development  (IMP)
cardiac septum morphogenesis  (IMP)
central nervous system development  (IBA,ISO)
chordate embryonic development  (IBA)
chromatin organization  (IEA)
chromatin remodeling  (IBA,IMP)
cognition  (ISO)
cranial nerve development  (IBA,ISO)
ear morphogenesis  (IMP)
embryonic hindlimb morphogenesis  (IMP)
epithelium development  (IMP)
face development  (ISO)
female genitalia development  (IMP)
genitalia development  (ISO)
heart morphogenesis  (IBA,IMP,ISO)
in utero embryonic development  (IMP,ISO)
inner ear morphogenesis  (IBA,IMP,ISO)
innervation  (IMP)
limb development  (ISO)
locomotory behavior  (IMP)
nose development  (IMP,ISO)
olfactory behavior  (IMP)
olfactory bulb development  (IMP)
olfactory nerve development  (IMP)
positive regulation of multicellular organism growth  (IMP)
positive regulation of transcription by RNA polymerase II  (IMP)
regulation of gene expression  (IBA)
regulation of growth hormone secretion  (ISO)
regulation of neurogenesis  (IMP)
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum  (IMP)
response to bacterium  (IEP)
retina development in camera-type eye  (ISO)
right ventricular compact myocardium morphogenesis  (IMP)
roof of mouth development  (IMP)
rRNA processing  (IEA)
secondary palate development  (ISO)
semicircular canal morphogenesis  (IGI)
sensory perception of sound  (IMP)
skeletal system development  (ISO)
T cell differentiation  (ISO)
tissue remodeling  (IMP)
transcription by RNA polymerase II  (IMP)
ventricular trabecula myocardium morphogenesis  (IMP)

Cellular Component
chromatin  (IBA)
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IDA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal atrioventricular cushion morphology  (IAGP)
abnormal auditory tube morphology  (IAGP)
abnormal behavior  (IEA)
abnormal bone marrow cell physiology  (IAGP)
abnormal brain development  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebellar hemisphere morphology  (IAGP)
abnormal cerebellar lobule formation  (IAGP)
abnormal cerebellum fissure morphology  (IAGP)
abnormal cerebellum hemisphere lobule morphology  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cerebellum vermis lobule IV morphology  (IAGP)
abnormal cerebellum vermis lobule IX morphology  (IAGP)
abnormal cerebellum vermis lobule morphology  (IAGP)
abnormal cerebellum vermis lobule V morphology  (IAGP)
abnormal cerebellum vermis lobule VIII morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal circulating enzyme level  (IAGP)
abnormal circulating lipid level  (IAGP)
abnormal circulating lipoprotein level  (IAGP)
abnormal circulating mineral level  (IAGP)
abnormal circulating protein level  (IAGP)
abnormal CNS glial cell morphology  (IAGP)
abnormal cochlea morphology  (IAGP)
abnormal cochlear hair cell morphology  (IAGP)
abnormal cochlear sensory epithelium morphology  (IAGP)
abnormal common carotid artery morphology  (IAGP)
abnormal common crus morphology  (IAGP)
abnormal compact bone morphology  (IAGP)
abnormal conotruncal ridge morphology  (IAGP)
abnormal coronary vein morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal cranial nerve morphology  (IAGP)
abnormal cranial neural crest cell migration  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal crista ampullaris morphology  (IAGP)
abnormal crista ampullaris neuroepithelium morphology  (IAGP)
abnormal digit development  (IAGP)
abnormal distortion product otoacoustic emission  (IAGP)
abnormal ear development  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal embryonic tissue physiology  (IAGP)
abnormal epigenetic regulation of gene expression  (IAGP)
abnormal estrous cycle  (IAGP)
abnormal external female genitalia morphology  (IAGP)
abnormal eye development  (IAGP)
abnormal eye morphology  (IAGP)
abnormal fetal cardiomyocyte physiology  (IAGP)
abnormal fourth pharyngeal arch artery morphology  (IAGP)
abnormal frontal lobe morphology  (IAGP)
abnormal glenoid fossa morphology  (IAGP)
abnormal glucose tolerance  (IAGP)
abnormal heart development  (IAGP)
abnormal heart morphology  (IAGP)
abnormal hindlimb morphology  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal hypothalamus physiology  (IAGP)
abnormal incudomalleolar joint morphology  (IAGP)
abnormal incus long process morphology  (IAGP)
abnormal incus morphology  (IAGP)
abnormal incus short process morphology  (IAGP)
abnormal induced morbidity/mortality  (IAGP)
abnormal inferior colliculus morphology  (IAGP)
abnormal inner ear canal fusion  (IAGP)
abnormal inner ear vestibule morphology  (IAGP)
abnormal innervation  (IAGP)
abnormal internal nares morphology  (IAGP)
abnormal lateral semicircular canal morphology  (IAGP)
abnormal lens development  (IAGP)
abnormal lobule simplex morphology  (IAGP)
abnormal malleus manubrium morphology  (IAGP)
abnormal malleus morphology  (IAGP)
abnormal maternal nurturing  (IAGP)
abnormal middle ear epithelium morphology  (IAGP)
abnormal middle ear ossicle morphology  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal myocardium compact layer morphology  (IAGP)
abnormal nasal pit morphology  (IAGP)
abnormal nasal placode morphology  (IAGP)
abnormal neocortex morphology  (IAGP)
abnormal neural crest cell migration  (IAGP)
abnormal neurohypophysis median eminence morphology  (IAGP)
abnormal neuron differentiation  (IAGP)
abnormal neuron number  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal neuronal precursor cell number  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal neuronal stem cell morphology  (IAGP)
abnormal olfactory bulb morphology  (IAGP)
abnormal olfactory epithelium cilium morphology  (IAGP)
abnormal olfactory epithelium morphology  (IAGP)
abnormal olfactory epithelium physiology  (IAGP)
abnormal olfactory lobe morphology  (IAGP)
abnormal olfactory sensory neuron morphology  (IAGP)
abnormal olfactory sensory neuron physiology  (IAGP)
abnormal olfactory system physiology  (IAGP)
abnormal oligodendrocyte apoptosis  (IAGP)
abnormal oligodendrocyte physiology  (IAGP)
abnormal optic cup morphology  (IAGP)
abnormal optic eminence morphology  (IAGP)
abnormal optic fissure closure  (IAGP)
abnormal otic capsule morphology  (IAGP)
abnormal otic vesicle development  (IAGP)
abnormal outer ear morphology  (IAGP)
abnormal oval window morphology  (IAGP)
abnormal palatal shelf fusion at midline  (IAGP)
abnormal parietal lobe morphology  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal pharyngeal arch morphology  (IAGP)
abnormal pituitary gland physiology  (IAGP)
abnormal placing response  (IAGP)
abnormal posterior semicircular canal morphology  (IAGP)
abnormal pulmonary trunk morphology  (IAGP)
abnormal pupil morphology  (IAGP)
abnormal Purkinje cell morphology  (IAGP)
abnormal response to stress-induced hyperthermia  (IAGP)
abnormal retina cone cell outer segment morphology  (IAGP)
abnormal retina rod cell outer segment morphology  (IAGP)
abnormal retrosplenial granular cortex morphology  (IAGP)
abnormal round window morphology  (IAGP)
abnormal secondary palate development  (IAGP)
abnormal semicircular canal morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal sixth pharyngeal arch artery morphology  (IAGP)
abnormal stapes crus morpholgy  (IAGP)
abnormal stapes footplate morphology  (IAGP)
abnormal stapes head morphology  (IAGP)
abnormal stapes morphology  (IAGP)
abnormal stationary movement  (IAGP)
abnormal subclavian artery morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal superior semicircular canal morphology  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal telencephalon morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal trigeminal ganglion morphology  (IAGP)
abnormal truncus arteriosus septation  (IAGP)
abnormal uterine horn morphology  (IAGP)
abnormal uterus morphology  (IAGP)
abnormal vagus nerve morphology  (IAGP)
abnormal vein morphology  (IAGP)
abnormal vestibular nerve morphology  (IAGP)
abnormal vestibulocochlear ganglion morphology  (IAGP)
absent cerebellum vermis  (IAGP)
absent cochlear microphonics  (IAGP)
absent distortion product otoacoustic emissions  (IAGP)
absent fourth pharyngeal arch artery  (IAGP)
absent hippocampus  (IAGP)
absent lateral semicircular canal  (IAGP)
absent nasal pit  (IAGP)
absent olfactory bulb  (IAGP)
absent optic cup  (IAGP)
absent posterior semicircular canal  (IAGP)
absent superior semicircular canal  (IAGP)
absent utricle  (IAGP)
absent vestibular saccule  (IAGP)
aorta coarctation  (IAGP)
aortic arch coarctation  (IAGP)
aortopulmonary window  (IAGP)
atrial septal defect  (IAGP)
atrioventricular cushion hypoplasia  (IAGP)
atrioventricular septal defect  (IAGP)
behavioral developmental delay  (IAGP)
bidirectional circling  (IAGP)
blepharitis  (IAGP)
cataract  (IAGP)
cerebellum hypoplasia  (IAGP)
cerebellum vermis hypoplasia  (IAGP)
choanal atresia  (IAGP)
circling  (IAGP)
cleft palate  (IAGP)
cleft secondary palate  (IAGP)
clitoris hypoplasia  (IAGP)
cochlear inner hair cell degeneration  (IAGP)
cochlear outer hair cell degeneration  (IAGP)
coloboma  (IAGP)
common atrioventricular valve  (IAGP)
conductive hearing impairment  (IAGP)
congestive heart failure  (IAGP)
conjunctivitis  (IAGP)
decreased apoptosis  (IAGP)
decreased body fat mass  (IAGP)
decreased body length  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mass  (IAGP)
decreased bone mineral content  (IAGP)
decreased bone mineral density  (IAGP)
decreased bone mineralization  (IAGP)
decreased bone ossification  (IAGP)
decreased bone trabecula number  (IAGP)
decreased brain internal capsule size  (IAGP)
decreased brain size  (IAGP)
decreased cell proliferation  (IAGP)
decreased cerebellar granule cell number  (IAGP)
decreased cerebellar granule cell precursor proliferation  (IAGP)
decreased circulating alanine transaminase level  (IAGP)
decreased circulating aspartate transaminase level  (IAGP)
decreased circulating calcium level  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating follicle stimulating hormone level  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating glycerol level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating luteinizing hormone level  (IAGP)
decreased circulating magnesium level  (IAGP)
decreased circulating potassium level  (IAGP)
decreased circulating serum albumin level  (IAGP)
decreased circulating total protein level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased cochlea coiling  (IAGP)
decreased cochlear nerve compound action potential  (IAGP)
decreased embryonic neuroepithelium thickness  (IAGP)
decreased femur compact bone thickness  (IAGP)
decreased fetal cardiomyocyte proliferation  (IAGP)
decreased grip strength  (IAGP)
decreased hematocrit  (IAGP)
decreased hemoglobin content  (IAGP)
decreased lateral semicircular canal size  (IAGP)
decreased lean body mass  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased long bone epiphyseal plate size  (IAGP)
decreased lumbar vertebrae number  (IEA)
decreased monocyte cell number  (IAGP)
decreased myelin sheath thickness  (IAGP)
decreased neuron number  (IAGP)
decreased neuronal precursor cell number  (IAGP)
decreased olfactory sensory neuron number  (IAGP)
decreased oligodendrocyte number  (IAGP)
decreased oligodendrocyte progenitor number  (IAGP)
decreased osteoblast cell number  (IAGP)
decreased oval window size  (IAGP)
decreased ovary weight  (IAGP)
decreased palatal rugae number  (IAGP)
decreased percent body fat/body weight  (IAGP)
decreased posterior semicircular canal size  (IAGP)
decreased primary ovarian follicle number  (IAGP)
decreased primordial ovarian follicle number  (IAGP)
decreased Purkinje cell number  (IAGP)
decreased red blood cell distribution width  (IAGP)
decreased retina cone cell number  (IAGP)
decreased round window size  (IAGP)
decreased secondary ovarian follicle number  (IAGP)
decreased startle reflex  (IAGP)
decreased superior semicircular canal size  (IAGP)
decreased susceptibility to noise-induced hearing loss  (IAGP)
decreased tertiary ovarian follicle number  (IAGP)
decreased testis weight  (IAGP)
decreased total body fat amount  (IAGP)
decreased trabecular bone thickness  (IAGP)
decreased volumetric bone mineral density  (IAGP)
delayed embryo turning  (IAGP)
delayed estrous cycle  (IAGP)
delayed fertility  (IAGP)
delayed sexual maturation  (IAGP)
delayed vaginal opening  (IAGP)
dilated lateral ventricle  (IAGP)
dilated third ventricle  (IAGP)
double inlet heart left ventricle  (IAGP)
double outlet right ventricle  (IAGP)
dry eyes  (IAGP)
dysmyelination  (IAGP)
ectopic cerebellar granule cells  (IAGP)
ectopic thymus  (IAGP)
edema  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enlarged third ventricle  (IAGP)
eyelid edema  (IAGP)
facial asymmetry  (IAGP)
fusion of glossopharyngeal and vagus nerve  (IAGP)
head bobbing  (IAGP)
head shaking  (IAGP)
head tilt  (IAGP)
head tossing  (IAGP)
hemorrhage  (IAGP)
hydrocephaly  (IAGP)
hyperactivity  (IAGP)
hypermyelination  (IAGP)
impaired coordination  (IAGP)
impaired cranial neural crest cell differentiation  (IAGP)
impaired hearing  (IAGP)
impaired olfaction  (IAGP)
impaired ovarian folliculogenesis  (IAGP)
impaired righting response  (IAGP)
impaired swimming  (IAGP)
increased atretic ovarian follicle number  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased blood uric acid level  (IAGP)
increased bone marrow adipose tissue amount  (IAGP)
increased bone trabecular spacing  (IAGP)
increased carbon dioxide production  (IAGP)
increased cardiomyocyte apoptosis  (IAGP)
increased cellular sensitivity to oxidative stress  (IAGP)
increased circulating alkaline phosphatase level  (IAGP)
increased cochlear hair cell number  (IAGP)
increased cochlear inner hair cell number  (IAGP)
increased cochlear outer hair cell number  (IAGP)
increased cranium height  (IAGP)
increased granulosa cell apoptosis  (IAGP)
increased habenula size  (IAGP)
increased locomotor activity  (IAGP)
increased mammillothalamic tract size  (IAGP)
increased middle ear goblet cell number  (IAGP)
increased neuron apoptosis  (IAGP)
increased neuron number  (IAGP)
increased neuronal precursor cell number  (IAGP)
increased neuronal stem cell self-renewal  (IAGP)
increased NK T cell number  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased oxygen consumption  (IAGP)
increased periosteum thickness  (IAGP)
increased susceptibility to otitis media  (IAGP)
increased thermal nociceptive threshold  (IAGP)
interrupted aortic arch  (IAGP)
interrupted aortic arch, type b  (IAGP)
keratoconjunctivitis sicca  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
lethality, complete penetrance  (IAGP)
long snout  (IAGP)
narrow eye opening  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neuron degeneration  (IAGP)
ocular hypertelorism  (IAGP)
olfactory bulb hypoplasia  (IAGP)
otosclerosis  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
premature neuronal precursor differentiation  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
pulmonary trunk hypoplasia  (IAGP)
Rathke's pouch hypoplasia  (IAGP)
reduced female fertility  (IAGP)
reduced fertility  (IAGP)
reduced male fertility  (IAGP)
retina coloboma  (IAGP)
sensorineural hearing impairment  (IAGP)
sex reversal  (IAGP)
short limbs  (IAGP)
short snout  (IAGP)
small cerebellum  (IAGP)
small endolymphatic duct  (IAGP)
small frontal bone  (IAGP)
small hippocampus  (IAGP)
small lens  (IAGP)
small mandible  (IAGP)
small maxilla  (IAGP)
small olfactory bulb  (IAGP)
small otic vesicle  (IAGP)
small ovary  (IAGP)
small stapes  (IAGP)
small stapes obturator foramen  (IAGP)
small thymus  (IAGP)
testis hypoplasia  (IAGP)
thin myocardium  (IAGP)
thin ventricle myocardium compact layer  (IAGP)
thin ventricular wall  (IAGP)
thymus hypoplasia  (IAGP)
trunk curl  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Complete screening of 50 patients with CHARGE syndrome for anomalies in the CHD7 gene using a denaturing high-performance liquid chromatography-based protocol: new guidelines and a proposal for routine diagnosis. Bilan F, etal., J Mol Diagn. 2012 Jan;14(1):46-55. doi: 10.1016/j.jmoldx.2011.08.003. Epub 2011 Oct 25.
2. Multiple mutations in mouse Chd7 provide models for CHARGE syndrome. Bosman EA, etal., Hum Mol Genet. 2005 Nov 15;14(22):3463-76. Epub 2005 Oct 5.
3. Genetic analysis of the CHD7 gene in Korean patients with CHARGE syndrome. Cho HJ, etal., Gene. 2013 Apr 1;517(2):164-8. doi: 10.1016/j.gene.2013.01.010. Epub 2013 Jan 17.
4. CHD7 deficiency in "Looper", a new mouse model of CHARGE syndrome, results in ossicle malformation, otosclerosis and hearing impairment. Ogier JM, etal., PLoS One. 2014 May 19;9(5):e97559. doi: 10.1371/journal.pone.0097559. eCollection 2014.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Molecular analysis of the CHD7 gene in CHARGE syndrome: identification of 22 novel mutations and evidence for a low contribution of large CHD7 deletions. Vuorela P, etal., Genet Med. 2007 Oct;9(10):690-4.
10. Novel CHD7 mutations contributing to the mutation spectrum in patients with CHARGE syndrome. Wessels K, etal., Eur J Med Genet. 2010 Sep-Oct;53(5):280-5. doi: 10.1016/j.ejmg.2010.07.002. Epub 2010 Jul 30.
11. CHD7 mutation spectrum in 28 Swedish patients diagnosed with CHARGE syndrome. Wincent J, etal., Clin Genet. 2008 Jul;74(1):31-8. doi: 10.1111/j.1399-0004.2008.01014.x. Epub 2008 Apr 28.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10512203   PMID:10922068   PMID:10932191   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:11919684   PMID:12466851   PMID:12477932  
PMID:12520002   PMID:14610273   PMID:14691545   PMID:15353999   PMID:15782199   PMID:15840001   PMID:15916118   PMID:16104381   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17334657  
PMID:17701983   PMID:17967808   PMID:18554416   PMID:18799693   PMID:18973680   PMID:19251738   PMID:19279158   PMID:19809474   PMID:19855134   PMID:20507341   PMID:20591827   PMID:20657823  
PMID:20736290   PMID:21267068   PMID:21532573   PMID:21596839   PMID:21677750   PMID:21873635   PMID:21875659   PMID:22539951   PMID:22658483   PMID:22705977   PMID:23012479   PMID:23285124  
PMID:23319608   PMID:23827709   PMID:23892456   PMID:24026680   PMID:24293546   PMID:24368733   PMID:24457600   PMID:24728844   PMID:24975120   PMID:25119037   PMID:25183173   PMID:25859222  
PMID:25985275   PMID:26102480   PMID:26584622   PMID:26670829   PMID:26928066   PMID:27174565   PMID:27955690   PMID:28165338   PMID:28317875   PMID:28373172   PMID:28671696   PMID:28931573  
PMID:29018080   PMID:29168327   PMID:29212025   PMID:29311329   PMID:29467333   PMID:29615807   PMID:30108144   PMID:30277262   PMID:30459807   PMID:30595499   PMID:30973865   PMID:31444215  
PMID:32325033   PMID:32610082   PMID:32883883   PMID:33060836   PMID:33127760   PMID:33846320   PMID:34004180   PMID:34124068   PMID:34321999   PMID:34474245   PMID:34588434   PMID:34732824  
PMID:35129866   PMID:35132236   PMID:35402599   PMID:35418650   PMID:36232804   PMID:36288662   PMID:36343670   PMID:37052590   PMID:37668839  


Genomics

Comparative Map Data
Chd7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3948,690,345 - 8,868,449 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl48,690,406 - 8,867,659 (+)EnsemblGRCm39 Ensembl
GRCm3848,690,402 - 8,868,449 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl48,690,406 - 8,867,659 (+)EnsemblGRCm38mm10GRCm38
MGSCv3748,618,068 - 8,793,957 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3648,617,551 - 8,793,957 (+)NCBIMGSCv36mm8
Celera48,587,948 - 8,703,577 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.68NCBI
CHD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38860,678,740 - 60,868,028 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl860,678,740 - 60,868,028 (+)EnsemblGRCh38hg38GRCh38
GRCh37861,591,299 - 61,780,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36861,753,893 - 61,942,019 (+)NCBINCBI36Build 36hg18NCBI36
Celera857,580,946 - 57,769,196 (+)NCBICelera
Cytogenetic Map8q12.2NCBI
HuRef857,078,404 - 57,267,234 (+)NCBIHuRef
CHM1_1861,643,239 - 61,832,394 (+)NCBICHM1_1
T2T-CHM13v2.0861,102,480 - 61,291,800 (+)NCBIT2T-CHM13v2.0
Chd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2521,812,007 - 21,995,358 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl521,812,070 - 21,995,358 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx524,042,693 - 24,226,869 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0525,632,041 - 25,815,380 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0525,412,324 - 25,595,635 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0521,769,087 - 21,952,036 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl521,830,882 - 21,950,696 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0526,520,706 - 26,702,242 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4522,549,237 - 22,710,257 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1522,591,442 - 22,710,257 (+)NCBI
Celera521,141,679 - 21,262,470 (+)NCBICelera
Cytogenetic Map5q13NCBI
Chd7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544417,858,771 - 18,067,248 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544417,859,999 - 18,067,623 (-)NCBIChiLan1.0ChiLan1.0
CHD7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1851,986,509 - 52,178,169 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0857,091,002 - 57,282,471 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1858,816,836 - 58,945,186 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl858,816,840 - 58,945,186 (+)Ensemblpanpan1.1panPan2
CHD7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12911,115,865 - 11,284,713 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2911,156,340 - 11,283,627 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2911,408,517 - 11,599,846 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02911,188,422 - 11,379,518 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2911,188,394 - 11,379,154 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12911,181,435 - 11,372,486 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02911,318,005 - 11,509,173 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02911,586,964 - 11,778,508 (+)NCBIUU_Cfam_GSD_1.0
Chd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530362,220,800 - 62,404,249 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649612,381,126 - 12,505,150 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649612,381,225 - 12,505,121 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHD7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl472,573,453 - 72,694,146 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1472,572,455 - 72,754,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2479,030,873 - 79,152,740 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHD7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1856,654,939 - 56,782,803 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl856,657,826 - 56,785,804 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603984,886,490 - 85,079,954 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chd7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474431,103,059 - 31,235,623 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474431,103,053 - 31,302,314 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chd7
5677 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1101
Count of miRNA genes:489
Interacting mature miRNAs:595
Transcripts:ENSMUST00000039267, ENSMUST00000051558, ENSMUST00000127476, ENSMUST00000129655, ENSMUST00000130709, ENSMUST00000170391, ENSMUST00000170457
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11049579Lmr9b_mleishmaniasis resistance 9b (mouse)4120657234Mouse
11049580Lmr9a_mleishmaniasis resistance 9 (mouse)4120657234Mouse
1301274Lmr9_mleishmaniasis resistance 9 (mouse)Not determined4120657234Mouse
10412079Sm1_msusceptibility to Schistosoma mansoni infection 1 (mouse)Not determined4122955614Mouse
1301510Bbaa13_mB.burgdorferi-associated arthritis 13 (mouse)Not determined4126395649Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse

Markers in Region
Chd7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A1UniSTS
cM Map41.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001277149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003954972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK035953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL805903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD540105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ102897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN717040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000039267   ⟹   ENSMUSP00000043903
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl48,690,921 - 8,866,810 (+)Ensembl
GRCm38.p6 Ensembl48,690,921 - 8,866,810 (+)Ensembl
RefSeq Acc Id: ENSMUST00000051558   ⟹   ENSMUSP00000059079
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl48,691,365 - 8,867,659 (+)Ensembl
GRCm38.p6 Ensembl48,691,365 - 8,867,659 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127476   ⟹   ENSMUSP00000118711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl48,690,470 - 8,785,591 (+)Ensembl
GRCm38.p6 Ensembl48,690,470 - 8,785,591 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129655   ⟹   ENSMUSP00000123241
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl48,710,340 - 8,751,562 (+)Ensembl
GRCm38.p6 Ensembl48,710,340 - 8,751,562 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130709
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl48,840,322 - 8,844,721 (+)Ensembl
GRCm38.p6 Ensembl48,840,322 - 8,844,721 (+)Ensembl
RefSeq Acc Id: ENSMUST00000170391   ⟹   ENSMUSP00000127007
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl48,751,438 - 8,867,224 (+)Ensembl
GRCm38.p6 Ensembl48,751,438 - 8,867,224 (+)Ensembl
RefSeq Acc Id: ENSMUST00000170457
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl48,690,406 - 8,755,906 (+)Ensembl
GRCm38.p6 Ensembl48,690,406 - 8,755,906 (+)Ensembl
RefSeq Acc Id: ENSMUST00000222546   ⟹   ENSMUSP00000152166
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl48,855,231 - 8,858,618 (+)Ensembl
GRCm38.p6 Ensembl48,855,231 - 8,858,618 (+)Ensembl
RefSeq Acc Id: NM_001277149   ⟹   NP_001264078
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,406 - 8,868,449 (+)NCBI
GRCm3848,690,406 - 8,868,449 (+)NCBI
Celera48,587,958 - 8,705,208 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001355382   ⟹   NP_001342311
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,751,324 - 8,868,449 (+)NCBI
GRCm3848,751,324 - 8,868,449 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538004   ⟹   XP_006538067
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,691,075 - 8,867,652 (+)NCBI
GRCm3848,691,258 - 8,867,654 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538005   ⟹   XP_006538068
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,345 - 8,867,654 (+)NCBI
GRCm3848,690,402 - 8,867,654 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538006   ⟹   XP_006538069
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,785,446 - 8,867,654 (+)NCBI
GRCm3848,785,446 - 8,867,654 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003954972
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,345 - 8,864,283 (+)NCBI
GRCm3848,690,402 - 8,864,034 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004941924
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,345 - 8,866,797 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004941925
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,345 - 8,864,289 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001264078   ⟸   NM_001277149
- Peptide Label: isoform 1
- UniProtKB: Q8C986 (UniProtKB/Swiss-Prot),   Q3TBU4 (UniProtKB/Swiss-Prot),   Q3TAG7 (UniProtKB/Swiss-Prot),   Q3TA86 (UniProtKB/Swiss-Prot),   Q8K244 (UniProtKB/Swiss-Prot),   A2AJK6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006538068   ⟸   XM_006538005
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006538067   ⟸   XM_006538004
- Peptide Label: isoform X1
- UniProtKB: Q8C986 (UniProtKB/Swiss-Prot),   Q3TBU4 (UniProtKB/Swiss-Prot),   Q3TAG7 (UniProtKB/Swiss-Prot),   Q3TA86 (UniProtKB/Swiss-Prot),   Q8K244 (UniProtKB/Swiss-Prot),   A2AJK6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006538069   ⟸   XM_006538006
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001342311   ⟸   NM_001355382
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000127007   ⟸   ENSMUST00000170391
RefSeq Acc Id: ENSMUSP00000152166   ⟸   ENSMUST00000222546
RefSeq Acc Id: ENSMUSP00000059079   ⟸   ENSMUST00000051558
RefSeq Acc Id: ENSMUSP00000118711   ⟸   ENSMUST00000127476
RefSeq Acc Id: ENSMUSP00000123241   ⟸   ENSMUST00000129655
RefSeq Acc Id: ENSMUSP00000043903   ⟸   ENSMUST00000039267
Protein Domains
BRK   Chromo   Helicase ATP-binding   Helicase C-terminal

Promoters
RGD ID:6835056
Promoter ID:MM_KWN:36616
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000039267,   ENSMUST00000051558,   UC008RXY.1,   UC008RXZ.1,   UC008RYB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3648,617,141 - 8,618,402 (+)MPROMDB
RGD ID:6835054
Promoter ID:MM_KWN:36617
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Spleen
Transcripts:OTTMUST00000010007
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3648,636,521 - 8,637,882 (+)MPROMDB
RGD ID:6882778
Promoter ID:EPDNEW_M4840
Type:initiation region
Name:Chd7_1
Description:Mus musculus chromodomain helicase DNA binding protein 7 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4841  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3848,690,437 - 8,690,497EPDNEW
RGD ID:6882780
Promoter ID:EPDNEW_M4841
Type:single initiation site
Name:Chd7_2
Description:Mus musculus chromodomain helicase DNA binding protein 7 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4840  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3848,714,444 - 8,714,504EPDNEW
RGD ID:6835055
Promoter ID:MM_KWN:36618
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000010008
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3648,766,476 - 8,766,976 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444748 AgrOrtholog
Ensembl Genes ENSMUSG00000041235 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000039267 UniProtKB/Swiss-Prot
  ENSMUST00000051558 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000127476.8 UniProtKB/TrEMBL
  ENSMUST00000129655.2 UniProtKB/TrEMBL
  ENSMUST00000170391.2 UniProtKB/TrEMBL
  ENSMUST00000222546.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/Swiss-Prot
  3.40.5.120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
InterPro BRK_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRK_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chromo-like_dom_sf UniProtKB/Swiss-Prot
  Chromo/chromo_shadow_dom UniProtKB/Swiss-Prot
  Chromo_domain UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  SNF2-like_sf UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
KEGG Report mmu:320790 UniProtKB/Swiss-Prot
MGD MGI:2444748 ENTREZGENE
NCBI Gene 320790 ENTREZGENE
PANTHER CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 UniProtKB/Swiss-Prot
  CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 UniProtKB/Swiss-Prot
  CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 UniProtKB/TrEMBL
  CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9 UniProtKB/TrEMBL
Pfam BRK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chromo UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
PhenoGen Chd7 PhenoGen
PROSITE CHROMO_2 UniProtKB/Swiss-Prot
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
SMART BRK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CHROMO UniProtKB/Swiss-Prot
  DEXDc UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF160481 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot
  SSF54160 UniProtKB/Swiss-Prot
UniProt A0A0R4J1U9_MOUSE UniProtKB/TrEMBL
  A0A1Y7VIV0_MOUSE UniProtKB/TrEMBL
  A2AJK6 ENTREZGENE
  A2AJK7_MOUSE UniProtKB/TrEMBL
  CHD7_MOUSE UniProtKB/Swiss-Prot
  E9PV74_MOUSE UniProtKB/TrEMBL
  Q3TA86 ENTREZGENE
  Q3TAG7 ENTREZGENE
  Q3TBU4 ENTREZGENE
  Q8C986 ENTREZGENE
  Q8K244 ENTREZGENE
UniProt Secondary Q3TA86 UniProtKB/Swiss-Prot
  Q3TAG7 UniProtKB/Swiss-Prot
  Q3TBU4 UniProtKB/Swiss-Prot
  Q8C986 UniProtKB/Swiss-Prot
  Q8K244 UniProtKB/Swiss-Prot