Myrf (myelin regulatory factor) - Rat Genome Database

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Gene: Myrf (myelin regulatory factor) Mus musculus
Analyze
Symbol: Myrf
Name: myelin regulatory factor
RGD ID: 1615698
MGI Page MGI
Description: Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including central nervous system myelin maintenance; positive regulation of myelination; and regulation of DNA-templated transcription. Located in endoplasmic reticulum membrane and nucleus. Is expressed in pigmented retinal epithelium; spinal cord; and spinal cord marginal layer. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; hyperopia; nanophthalmos; and primary angle-closure glaucoma. Orthologous to human MYRF (myelin regulatory factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6030439E18; Gm1804; Gm98; KIAA0954; Mrf; myelin gene regulatory factor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,185,635 - 10,218,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,185,636 - 10,218,112 (-)EnsemblGRCm39 Ensembl
GRCm381910,208,271 - 10,240,777 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,208,272 - 10,240,748 (-)EnsemblGRCm38mm10GRCm38
MGSCv371910,282,761 - 10,315,238 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,275,316 - 10,307,793 (-)NCBIMGSCv36mm8
Celera1910,904,189 - 10,936,740 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice. Garnai SJ, etal., PLoS Genet. 2019 May 2;15(5):e1008130. doi: 10.1371/journal.pgen.1008130. eCollection 2019 May.
2. Oligodendroglia Are Particularly Vulnerable to Oxidative Damage after Neurotrauma In Vivo. Giacci MK, etal., J Neurosci. 2018 Jul 18;38(29):6491-6504. doi: 10.1523/JNEUROSCI.1898-17.2018. Epub 2018 Jun 18.
3. Truncation mutations in MYRF underlie primary angle closure glaucoma. Ouyang J, etal., Hum Genet. 2023 Jan;142(1):103-123. doi: 10.1007/s00439-022-02487-0. Epub 2022 Sep 21.
4. De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders. Qi H, etal., PLoS Genet. 2018 Dec 10;14(12):e1007822. doi: 10.1371/journal.pgen.1007822. eCollection 2018 Dec.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Large-Scale Targeted Sequencing Study of Ischemic Stroke in the Han Chinese Population. Shi M, etal., J Am Heart Assoc. 2022 Oct 4;11(19):e025245. doi: 10.1161/JAHA.122.025245. Epub 2022 Oct 4.
9. Co-transplantation of MRF-overexpressing oligodendrocyte precursor cells and Schwann cells promotes recovery in rat after spinal cord injury. Xie XM, etal., Neurobiol Dis. 2016 Oct;94:196-204. doi: 10.1016/j.nbd.2016.06.016. Epub 2016 Jun 29.
10. Downregulation of microRNA-199a-5p alleviated lidocaine-induced sensory dysfunction and spinal cord myelin lesions in a rat model. Zhang Z, etal., Toxicol Lett. 2021 Jan 1;336:1-10. doi: 10.1016/j.toxlet.2020.11.001. Epub 2020 Nov 6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17967808   PMID:18799693  
PMID:19596243   PMID:21267068   PMID:21873635   PMID:21938520   PMID:22365546   PMID:22956843   PMID:23332759   PMID:23575864   PMID:23966833   PMID:24204311   PMID:24257626   PMID:25324381  
PMID:25568100   PMID:25680202   PMID:25789755   PMID:26395480   PMID:26525805   PMID:26928066   PMID:27149841   PMID:27455109   PMID:27532821   PMID:28160598   PMID:28336932   PMID:28441531  
PMID:28695847   PMID:29361054   PMID:29472293   PMID:29500351   PMID:29556912   PMID:30076300   PMID:30166609   PMID:30249802   PMID:30996143   PMID:31081019   PMID:31753579   PMID:31828317  
PMID:32042175   PMID:32075970   PMID:32236127   PMID:32266943   PMID:32290105   PMID:33472075   PMID:33646289   PMID:34260928   PMID:34615523   PMID:36730342   PMID:36739968   PMID:36779010  
PMID:37371026   PMID:38246987   PMID:38355793  


Genomics

Comparative Map Data
Myrf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,185,635 - 10,218,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,185,636 - 10,218,112 (-)EnsemblGRCm39 Ensembl
GRCm381910,208,271 - 10,240,777 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,208,272 - 10,240,748 (-)EnsemblGRCm38mm10GRCm38
MGSCv371910,282,761 - 10,315,238 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,275,316 - 10,307,793 (-)NCBIMGSCv36mm8
Celera1910,904,189 - 10,936,740 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.54NCBI
MYRF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,752,636 - 61,788,518 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,752,636 - 61,788,518 (+)EnsemblGRCh38hg38GRCh38
GRCh371161,520,108 - 61,555,990 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,279,437 - 61,312,565 (+)NCBINCBI36Build 36hg18NCBI36
Build 341161,279,436 - 61,312,565NCBI
Celera1158,855,535 - 58,891,401 (+)NCBICelera
Cytogenetic Map11q12.2NCBI
HuRef1157,848,377 - 57,884,223 (+)NCBIHuRef
CHM1_11161,403,340 - 61,439,204 (+)NCBICHM1_1
T2T-CHM13v2.01161,741,556 - 61,777,435 (+)NCBIT2T-CHM13v2.0
Myrf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,279,057 - 216,311,155 (-)NCBIGRCr8
mRatBN7.21206,854,175 - 206,886,276 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1206,854,175 - 206,886,157 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,232,584 - 215,264,503 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,287,795 - 222,319,653 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,982,795 - 215,014,652 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,260,558 - 226,292,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,260,558 - 226,292,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,205,242 - 233,237,579 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,699,254 - 212,726,526 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11212,857,689 - 212,887,553 (-)NCBI
Celera1204,350,584 - 204,382,768 (-)NCBICelera
Cytogenetic Map1q43NCBI
Myrf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555115,927,698 - 5,942,242 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555115,927,103 - 5,949,289 (-)NCBIChiLan1.0ChiLan1.0
MYRF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,920,967 - 62,956,861 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,964,615 - 64,000,503 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01157,052,219 - 57,088,105 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,412,780 - 60,448,579 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1160,412,780 - 60,448,579 (+)Ensemblpanpan1.1panPan2
MYRF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,690,073 - 54,723,046 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,692,453 - 54,723,085 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1853,264,908 - 53,297,870 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01855,736,923 - 55,769,914 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1855,736,923 - 55,771,756 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,797,500 - 54,830,489 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01854,419,143 - 54,452,067 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01855,299,419 - 55,332,436 (-)NCBIUU_Cfam_GSD_1.0
Myrf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,222,574 - 11,270,024 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365811,338,762 - 1,367,104 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365811,335,969 - 1,367,104 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYRF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.129,761,230 - 9,795,873 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.229,314,215 - 9,345,474 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYRF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,066,277 - 12,103,091 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038109,440,246 - 109,477,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myrf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624926617,303 - 636,080 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624926615,991 - 636,167 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myrf
1023 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1083
Count of miRNA genes:520
Interacting mature miRNAs:643
Transcripts:ENSMUST00000088013
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
38455997Cdtm2_mCD62L+ CD8 TM cells 2 (mouse)19997736419977364Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001404113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006526934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011247222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036161543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036161545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC026761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW455580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC157942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX565711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000088013   ⟹   ENSMUSP00000085329
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,185,636 - 10,218,112 (-)Ensembl
GRCm38.p6 Ensembl1910,208,272 - 10,240,748 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186056   ⟹   ENSMUSP00000140871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,187,068 - 10,218,109 (-)Ensembl
GRCm38.p6 Ensembl1910,209,704 - 10,240,745 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186854   ⟹   ENSMUSP00000140838
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,187,664 - 10,194,892 (-)Ensembl
GRCm38.p6 Ensembl1910,210,300 - 10,217,528 (-)Ensembl
Ensembl Acc Id: ENSMUST00000189439
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,203,382 - 10,218,112 (-)Ensembl
GRCm38.p6 Ensembl1910,226,018 - 10,240,748 (-)Ensembl
Ensembl Acc Id: ENSMUST00000189897   ⟹   ENSMUSP00000139601
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,187,749 - 10,217,968 (-)Ensembl
GRCm38.p6 Ensembl1910,210,385 - 10,240,604 (-)Ensembl
Ensembl Acc Id: ENSMUST00000190922
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,186,669 - 10,218,112 (-)Ensembl
GRCm38.p6 Ensembl1910,209,305 - 10,240,748 (-)Ensembl
RefSeq Acc Id: NM_001033481   ⟹   NP_001028653
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,095 (-)NCBI
GRCm381910,208,271 - 10,240,748 (-)NCBI
MGSCv371910,282,761 - 10,315,238 (-)RGD
Celera1910,904,189 - 10,936,740 (-)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001404113   ⟹   NP_001391042
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,202,619 (-)NCBI
RefSeq Acc Id: XM_006526927   ⟹   XP_006526990
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,134 (-)NCBI
GRCm381910,208,271 - 10,240,777 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006526928   ⟹   XP_006526991
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,133 (-)NCBI
GRCm381910,208,271 - 10,240,777 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006526929   ⟹   XP_006526992
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,133 (-)NCBI
GRCm381910,208,271 - 10,240,777 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006526930   ⟹   XP_006526993
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,134 (-)NCBI
GRCm381910,208,271 - 10,240,777 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006526931   ⟹   XP_006526994
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,134 (-)NCBI
GRCm381910,208,271 - 10,240,777 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006526932   ⟹   XP_006526995
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,133 (-)NCBI
GRCm381910,208,271 - 10,240,776 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006526934   ⟹   XP_006526997
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,133 (-)NCBI
GRCm381910,208,271 - 10,240,777 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011247222   ⟹   XP_011245524
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,134 (-)NCBI
GRCm381910,208,271 - 10,240,777 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036161543   ⟹   XP_036017436
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,202,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036161545   ⟹   XP_036017438
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,185,635 - 10,218,132 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001028653   ⟸   NM_001033481
- Peptide Label: isoform 1
- UniProtKB: Q3UR85 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006526994   ⟸   XM_006526931
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006526992   ⟸   XM_006526929
- Peptide Label: isoform X4
- UniProtKB: F8WJJ9 (UniProtKB/Swiss-Prot),   B2RXQ7 (UniProtKB/Swiss-Prot),   Q3V3K4 (UniProtKB/Swiss-Prot),   Q3UR85 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006526995   ⟸   XM_006526932
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006526993   ⟸   XM_006526930
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006526990   ⟸   XM_006526927
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006526997   ⟸   XM_006526934
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006526991   ⟸   XM_006526928
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011245524   ⟸   XM_011247222
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSMUSP00000140838   ⟸   ENSMUST00000186854
Ensembl Acc Id: ENSMUSP00000085329   ⟸   ENSMUST00000088013
Ensembl Acc Id: ENSMUSP00000140871   ⟸   ENSMUST00000186056
Ensembl Acc Id: ENSMUSP00000139601   ⟸   ENSMUST00000189897
RefSeq Acc Id: XP_036017438   ⟸   XM_036161545
- Peptide Label: isoform X11
RefSeq Acc Id: XP_036017436   ⟸   XM_036161543
- Peptide Label: isoform X8
RefSeq Acc Id: NP_001391042   ⟸   NM_001404113
- Peptide Label: isoform 2
Protein Domains
Peptidase S74

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UR85-F1-model_v2 AlphaFold Q3UR85 1-1138 view protein structure

Promoters
RGD ID:13678894
Promoter ID:EPDNEW_M23596
Type:initiation region
Name:Myrf_1
Description:Mus musculus myelin regulatory factor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381910,240,720 - 10,240,780EPDNEW
RGD ID:6830094
Promoter ID:MM_KWN:26375
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:UC008GPK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361910,293,876 - 10,294,376 (-)MPROMDB
RGD ID:6830097
Promoter ID:MM_KWN:26376
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver,   Lung
Transcripts:ENSMUST00000088013,   ENSMUST00000096230,   NM_001033481,   UC008GPL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361910,314,859 - 10,315,359 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2684944 AgrOrtholog
Ensembl Genes ENSMUSG00000036098 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000088013 ENTREZGENE
  ENSMUST00000088013.12 UniProtKB/Swiss-Prot
  ENSMUST00000186056 ENTREZGENE
  ENSMUST00000186056.7 UniProtKB/Swiss-Prot
  ENSMUST00000186854.7 UniProtKB/TrEMBL
  ENSMUST00000189897 ENTREZGENE
  ENSMUST00000189897.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.1390 UniProtKB/Swiss-Prot
InterPro MRF-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRF_C1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRF_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDT80_DNA-bd_dom UniProtKB/Swiss-Prot
  NDT80_DNA-bd_dom_sf UniProtKB/Swiss-Prot
  p53-like_TF_DNA-bd UniProtKB/Swiss-Prot
  S74_ICA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:225908 UniProtKB/Swiss-Prot
MGD MGI:2684944 ENTREZGENE
NCBI Gene 225908 ENTREZGENE
PANTHER PTHR13029:SF16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MRF_C1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRF_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDT80_PhoG UniProtKB/Swiss-Prot
  Peptidase_S74 UniProtKB/Swiss-Prot
PhenoGen Myrf PhenoGen
PROSITE ICA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDT80 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49417 UniProtKB/Swiss-Prot
UniProt A0A087WRZ9_MOUSE UniProtKB/TrEMBL
  B2RXQ7 ENTREZGENE
  F8WJJ9 ENTREZGENE
  MYRF_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3V3K4 ENTREZGENE
UniProt Secondary B2RXQ7 UniProtKB/Swiss-Prot
  F8WJJ9 UniProtKB/Swiss-Prot
  Q3V3K4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-08 Myrf  myelin regulatory factor  Gm98  predicted gene 98  Symbol and/or name change 5135510 APPROVED