Krt26 (keratin 26) - Rat Genome Database

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Gene: Krt26 (keratin 26) Mus musculus
Analyze
Symbol: Krt26
Name: keratin 26
RGD ID: 1615562
MGI Page MGI
Description: Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Is expressed in vibrissa epidermal component. Orthologous to human KRT26 (keratin 26).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4732407F15Rik; CK-26; cytokeratin-26; K26; keratin 25B; keratin, type I cytoskeletal 26; keratin-26; Krt25b; type I inner root sheath-specific keratin-K25irs2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,219,310 - 99,228,791 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,219,376 - 99,228,792 (-)EnsemblGRCm39 Ensembl
GRCm381199,328,484 - 99,337,965 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,328,550 - 99,337,966 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,189,798 - 99,199,279 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,103,480 - 100,112,965 (-)NCBIMGSCv36mm8
MGSCv361199,144,572 - 99,154,057 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1162.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16831889   PMID:21267068   PMID:21873635   PMID:38355793  


Genomics

Comparative Map Data
Krt26
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,219,310 - 99,228,791 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,219,376 - 99,228,792 (-)EnsemblGRCm39 Ensembl
GRCm381199,328,484 - 99,337,965 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,328,550 - 99,337,966 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,189,798 - 99,199,279 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,103,480 - 100,112,965 (-)NCBIMGSCv36mm8
MGSCv361199,144,572 - 99,154,057 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1162.92NCBI
KRT26
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381740,766,238 - 40,772,201 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1740,766,238 - 40,772,201 (-)EnsemblGRCh38hg38GRCh38
GRCh371738,922,490 - 38,928,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,176,016 - 36,181,937 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,157,799 - 36,181,937NCBI
Celera1735,584,037 - 35,589,958 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1734,716,863 - 34,722,780 (-)NCBIHuRef
CHM1_11739,157,819 - 39,163,738 (-)NCBICHM1_1
T2T-CHM13v2.01741,630,552 - 41,636,512 (-)NCBIT2T-CHM13v2.0
Krt26
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81084,777,137 - 84,791,756 (-)NCBIGRCr8
mRatBN7.21084,280,965 - 84,295,575 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1084,281,162 - 84,292,466 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1089,225,468 - 89,234,501 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01088,723,585 - 88,732,619 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01084,115,575 - 84,124,603 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01087,239,722 - 87,248,589 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1087,238,723 - 87,248,632 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01087,035,420 - 87,044,512 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41088,232,055 - 88,240,699 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11088,246,424 - 88,255,069 (-)NCBI
Celera1083,021,282 - 83,029,760 (-)NCBICelera
Cytogenetic Map10q31NCBI
Krt26
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545115,230,780 - 15,236,784 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545115,230,834 - 15,236,699 (-)NCBIChiLan1.0ChiLan1.0
KRT26
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21924,176,817 - 24,186,349 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11726,067,258 - 26,076,789 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01716,512,055 - 16,517,973 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11716,737,108 - 16,743,025 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1716,737,108 - 16,743,025 (+)Ensemblpanpan1.1panPan2
KRT26
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,924,248 - 21,929,809 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,924,248 - 21,929,809 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha921,397,517 - 21,402,890 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0922,717,338 - 22,722,912 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl922,717,338 - 22,722,912 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1921,492,178 - 21,497,521 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0921,750,781 - 21,756,349 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0921,875,167 - 21,880,734 (+)NCBIUU_Cfam_GSD_1.0
Krt26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560221,326,477 - 21,332,961 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649015,742,328 - 15,748,494 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649015,742,328 - 15,748,494 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRT26
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1221,689,145 - 21,695,847 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11221,689,150 - 21,696,096 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,792,911 - 21,799,834 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRT26
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11665,412,225 - 65,413,931 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1665,412,753 - 65,418,344 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607736,294,422 - 36,300,065 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Krt26
215 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:432
Count of miRNA genes:302
Interacting mature miRNAs:352
Transcripts:ENSMUST00000100482, ENSMUST00000148770
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1301153Estq3_mestradiol regulated response QTL 3 (mouse)Not determined119689769399327028Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000100482   ⟹   ENSMUSP00000098051
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1199,219,440 - 99,228,792 (-)Ensembl
GRCm38.p6 Ensembl1199,328,614 - 99,337,966 (-)Ensembl
Ensembl Acc Id: ENSMUST00000148770
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1199,219,376 - 99,228,791 (-)Ensembl
GRCm38.p6 Ensembl1199,328,550 - 99,337,965 (-)Ensembl
RefSeq Acc Id: NM_001033397   ⟹   NP_001028569
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391199,219,310 - 99,228,791 (-)NCBI
GRCm381199,328,484 - 99,337,965 (-)NCBI
MGSCv371199,189,798 - 99,199,279 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001028569 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI16673 (Get FASTA)   NCBI Sequence Viewer  
  BAE21173 (Get FASTA)   NCBI Sequence Viewer  
  BAE37035 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000098051
  ENSMUSP00000098051.3
GenBank Protein Q3TRJ4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001028569   ⟸   NM_001033397
- UniProtKB: Q3V1H8 (UniProtKB/Swiss-Prot),   Q3TRJ4 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000098051   ⟸   ENSMUST00000100482
Protein Domains
IF rod

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3TRJ4-F1-model_v2 AlphaFold Q3TRJ4 1-462 view protein structure

Promoters
RGD ID:8676562
Promoter ID:EPDNEW_M16311
Type:initiation region
Name:Krt26_1
Description:Mus musculus keratin 26 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381199,337,965 - 99,338,025EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444913 AgrOrtholog
Ensembl Genes ENSMUSG00000075570 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000100482 ENTREZGENE
  ENSMUST00000100482.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
  Single helix bin UniProtKB/Swiss-Prot
  Vasodilator-stimulated phosphoprotein UniProtKB/Swiss-Prot
InterPro IF_rod_dom UniProtKB/Swiss-Prot
  Keratin_I UniProtKB/Swiss-Prot
KEGG Report mmu:320864 UniProtKB/Swiss-Prot
MGD MGI:2444913 ENTREZGENE
NCBI Gene 320864 ENTREZGENE
PANTHER KERATIN, TYPE I CYTOSKELETAL 26 UniProtKB/Swiss-Prot
  PTHR23239 UniProtKB/Swiss-Prot
Pfam Filament UniProtKB/Swiss-Prot
PhenoGen Krt26 PhenoGen
PRINTS TYPE1KERATIN UniProtKB/Swiss-Prot
PROSITE IF_ROD_2 UniProtKB/Swiss-Prot
SMART Filament UniProtKB/Swiss-Prot
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/Swiss-Prot
UniProt K1C26_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3V1H8 ENTREZGENE
UniProt Secondary Q3V1H8 UniProtKB/Swiss-Prot